PDF Testosterone, Calculated Free, Bioavailable, and Total
globulin (SHBG). Free testosterone is the small amount of testosterone circulating unbound. Blood testosterone levels are dependent on rates of production, interconversion, metabolic clearance, and SHBG concentration. SHBG levels are altered by medications, disease, sex steroids, and insulin. SHBG increases with age in men and decreases with ... ................
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