Complex Inheritence/Human Genetics Study Guide (Chapter 12)
Complex Inheritence/Human Genetics Study Guide (Chapter 12)
• Understand the following modes of inheritance, and examples of each:
1) Incomplete dominance
2) Codominance
3) Simple Recessive Inheritance
4) Simple Dominant Inheritance
5) X-linked traits
6) Multiple alleles
7) Polygenic Inheritance
*Know how to complete Punnett squares and determine probabilities for #1-#5.
• What diseases have both genetic and environmental factors that can cause them? What are the environmental factors?
• Expect problems concerning: snapdragons, blood types, Fruit Fly eye color, or any of the following diseases/conditions:
1) Hemophilia (A.K.A. Royal Hemophilia)
2) Cystic Fibrosis
3) Huntington’s Disease
4) Color Blindness
5) Sickle Cell Anemia
6) Down’s Syndrome
*Know the basic symptoms and modes of inheritance for all of the above
• What is nondisjunction? How is this related to Trisomy 21 (A.K.A. Down’s Syndrome)?
• Why is the trait for Sickle Cell so prevalent in African Americans? What is the link between Sickle Cell and Malaria?
• Which disease can be recognized by a karyotype?
• What is a pedigree? Be able to interpret a pedigree, including:
1) Male/Female, relationships of individuals using the Roman Numeral and number
2) Predict genotypes of individuals
3) Predict the mode of inheritance
4) Predict the probability of offspring genotypes
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