Gastroesophageal Reflux Disease: Introduction - Hopkins Medicine

Mechanism of gastroesophageal reflux disease. A weak antireflux barrier causes reflux in the majority of patients (Figure 4). Gastroesophageal reflux disease most often occurs when LES pressure (measured manometrically) is low or the normal angulation of the EG junction is lost (as occurs when a hiatus hernia is present) (Figure 5). Figure 5. ................
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