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Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive studyLi Tan1,#, Qi Wang2,#, Duanyang Zhang1, Jinya Ding3, Qianchuan Huang3, Yi-Quan Tang4, Qiongshu Wang1*, Hongming Miao5*1Department of Disease Control and Prevention, General Hospital of Central Theater Command, Wuhan, Hubei province, 430015, People’s Republic of China2General Hospital of Central Theater Command, Wuhan, Hubei province, 430015, People’s Republic of China3Department of Laboratory, General Hospital of Central Theater Command, Wuhan, Hubei province, 430015, People’s Republic of China4MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK5Department of Biochemistry and Molecular Biology, Third Military Medical University (Army Medical University), Chongqing, 400038, People’s Republic of China#These authors contributed equally to this work*Correspondence to:Hongming Miao, No. 30 Gaotanyan Street, Shapingba, Chongqing 400038, People’s Republic of China, hongmingmiao@, Tel: 86-13678484686;Qiongshu Wang, No. 627 Wuluo Road, Wuchang District, Wuhan, Hubei province, 430015, People’s Republic of China, whzyywqs@, Tel: 86-13871162270Supplementary tablesSupplementary Table 1. Basic information of 12 death cases of COVID-19 patientsCodeAge(year)GenderTreatment time (day)Initial symptomsMaximum temperature (°C)CT imageMedical historyP179male24fever; hypertension 38.2ground-glass shadow of both lungs hypertension;diabetes ;renal insufficiencyP293male20fever;cough40ground-glass shadow of both lungsdiabetes;hypertension;coronary heart diseaseP396male10diarrhea38.9Inflammation in both lungshypertension;cardiac insufficiency;renal insufficiencyP490male15cough; expectoration39not detectedhypertension;cardiac insufficiency;renal insufficiencyP596male17fever;fear of cold;cough39.3ground-glass shadow of both lungsdiabetes;hypertension;coronary heart diseaseP631female25muscular soreness39.5ground-glass shadow of both lungshealthyP791male15fever;cough38.6ground-glass shadow of both lungshypertension;coronary heart diseaseP876male15fever;muscular soreness38.5ground-glass shadow of both lungsliver?cirrhosis;osteoporosis;P940male20fever;cough40.2ground-glass shadow of both lungsfatty liverP1073male26fever;cough38.7Infection of both lungsfatty liverP1167male28fever;muscular soreness38inflammation in lower right lungcholecystectomy;hepatic nodule resectionP1284male28fever38.2ground-glass shadow of both lungsdiabetes;hypertension;coronary heart disease n=12; male/female ratio=11:1; average age =76 years; average treatment time: 20 daysSupplementary Table 2. Basic information of 7 cases of severe-cured patients with COVID-19codeAge(year)GenderTreatment time(day)Initial symptomsMaximum temperature (°C)CT imageMedical historyP177female37fever;cough38.2ground-glass shadow of both lungshypertensionP262female41fever;fear of cold40ground-glass shadow of both lungsdiabetes;hypertensionP348male34fever;fear of cold38.9ground-glass shadow of both lungshypertension;fatty liverP456male37fever39ground-glass shadow of both lungstuberculosisP529female39fever;fear of cold39.3ground-glass shadow of both lungshealthyP631male30fever;cough39.5ground-glass shadow of both lungshealthyP741male27fever;cough38.6ground-glass shadow of both lungshealthy n=7; male/female ratio=4:3; average age =35 years; average treatment time: 35 days; severe-cured patients: the severe type of patients with a cured outcomeSupplementary Table 3. Basic information of 11 cases of moderate-cured patients with COVID-19CodeAge(year)GenderTreatment time (day)Initial symptomsMaximum temperature (°C)CT imageMedical historyP140female24fever;cough;fatigue37.5infections in lower right lungshealthyP269female24fever38ground-glass shadow of both lungshealthyP351female29fever38.5ground-glass shadow of both lungshypertensionP431male26muscular?soreness?38.5ground-glass shadow of both lungshealthyP555male32fever;muscular?soreness37.7ground-glass shadow of both lungshealthyP656female23fever;muscular?soreness38.5ground-glass shadow of both lungspyelonephritis P761female27fever;cough;muscular?soreness38ground-glass shadow of both lungshealthyP854female23fever;cough;fatigue37.4ground-glass shadow of both lungshealthyP950female27fever;cough;fatigue38ground-glass shadow of both lungsgynopathy?P1017male23fever;muscular?soreness38.5ground-glass shadow of both lungsobesityP1153female28cough;muscular?soreness? 37.8ground-glass shadow of both lungshealthy n=11; male/female ratio=3:8; average age =49 years; average treatment time: 26 days; moderate-cured patients: the moderate type of patients with a cured outcome ................
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