PDF Cardiovascular Disease Prevention in Women
CARDIOVASCULAR DISEASE PREVENTION IN WOMEN
Kerunne S. Ketlogetswe MD, MHS MedStar Heart and Vascular Institute
1
Objectives
? Discuss strategies to assess and stratify women into high risk, at risk, and ideal health categories for cardiovascular disease (CVD)
? Summarize lifestyle approaches to the prevention of CVD in women
? Review American Heart Association (AHA) 2011 Guidelines approaches to CVD prevention for patients with hypertension, lipid abnormalities, and diabetes, with a focus on effectiveness in practice
? Review AHA 2011 Guidelines approach to pharmacological intervention for women at risk for cardiovascular events
? Summarize commonly used therapies that should not be initiated for the prevention or treatment of CVD, because they lack benefit, or because risks outweigh benefits
2
The Scope of the Problem
? Heart disease is the leading killer of women
? Cardiovascular disease is BY FAR the biggest killer of women
? Roughly 401,000 deaths/year from CVD (vs. 386,000 men)
? 176,255 deaths/year from CAD ? Vs 39,520 deaths from breast cancer
Heart Disease and Stroke Statistics - 2013 Update, AHA
The Scope of the Problem
One woman dies every minute from cardiovascular
disease in the U.S.!
Heart Disease and Stroke Statistics - 2013 Update, AHA
Age-adjusted Death Rates for American Women: U.S. 2006
150.0
130.0
100.0 Per 100,000 Population
50.0
0.0
101.5 84.5 58.9
57.0
41.0 32.3 34.9
Black/African American White Hispanic Asian
39.0 41.3 18.1
14.1
32.2 23.0 14.8 11.7
CHD
Stroke
Lung Cancer* Breast Cancer*
Sources: Adapted from Lloyd-Jones, Adams, et al (2010).
* Centers for Disease Control and Prevention, National Center for Health Statistics, Health
5
Data Interactive, 2005-2007.
Number
Annual Number of U.S. Adults Diagnosed with Myocardial Infarction and Fatal CHD by
Age and Sex Categories: 1987-2004
Age in Years
6
Source: Adapted from Rosamond 2008
550,000
Number of Cardiovascular Disease Deaths:
U.S. Men and Women 1980-2007
500,000 450,000
Men Women
Number
400,000
350,000
1980
1985
1990
1995
2000
2007
Year
7
Source: Adapted Rosamond 2008 and Roger 2011
Women Receive Fewer Interventions to Prevent and
Treat Heart Disease
? Less cholesterol screening ? Fewer lipid-lowering therapies ? Less use of heparin, beta-blockers and
aspirin during myocardial infarction ? Less antiplatelet therapy for secondary
prevention ? Fewer referrals to cardiac rehabilitation ? Fewer implantable cardioverter-defibrillators
compared to men with the same recognized indications
8
Sources: Chandra 1998, Nohria 1998, Scott 2004, O'Meara 2004, Hendrix 2005, Chou 2007, Hernandez 2007, Cho 2008
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