Nordic Summer School of Cancer Epidemiology



Nordic Summer School of Cancer Epidemiology, phase III

Virrat Winter Symposium 2016

Virrat, Finland, 29-31 January 2016

Coordinated by Eero Pukkala

Finnish Cancer Registry (cancerregistry.fi) &

School of Health Sciences, University of Tampere (uta.fi/hes/en)

Program

Nordic Summer School of Cancer Epidemiology

Phase III: Virrat Winter Symposium 2016

Virrat, Finland, 29-31 January 2016

PROGRAM

FRIDAY, 29 January

16:00 Bus from Tampere Railway station at 16:00 => Airport at about 16:25

18:15 Arrival to Virrat, Room occupation

18:45 Welcome meal (restaurant)

19:15 OPENING SESSION (priest house)

Eero Pukkala: Opening of the Virrat Winter Symposium;

practical information

Solveig Hofvind: Results of chairperson election; tasks of a chairman of a scientific symposium (max 5 minute presentation)

19:30-21:00 SESSION I – Descriptive epidemiology

Chairperson: Petra Makkonen (co-chair: Gerda Engholm)

Student presentations: 15 minutes plus 5 minutes discussion time

Mithila Shrestha: INCIDENCE TRENDS OF GLIOMAS IN FINLAND, 1970-2013

Christiana Opokuaah Appiah: CERVICAL CANCER IN NORWAY AND FINLAND: A COMPARISON OF INCIDENCE RATES AND TRENDS

Gerda Engholm: What else you can do with NORDCAN?

21:00 Poster hanging

SATURDAY, 30 January

8.00 Breakfast (restaurant)

8.30-10:10 SESSION II – Aetiology of cancer

Chairperson: Gunvor Gipling Wåde (co-chair: Bendix Carstensen)

Adalbjorg Kristbjornsdottir: CANCER INCIDENCE AND USE OF GEOTHERMAL HOT WATER FOR HEATING AND BATHING

Sofie Have Hoffmann: RISK OF TESTICULAR CANCER WITH CRYPTORCHIDISM - A DANISH COHORT STUDY

Eva María Guðmundsdóttir: CANCER INCIDENCE AMONG ICELANDIC PILOTS

Shadi Azam: THE ASSOCIATION OF PHYSICAL ACTIVITY WITH MAMMOGRAPHIC DENSITY

Lene Lerche: PHYSICAL FITNESS IN THE DANISH COHORT “DIET, CANCER AND HEALTH – NEXT GENERATIONS” – A VALIDATION STUDY

Jadwiga Buchwald: NICOTINE METABOLISM RATE AND TOBACCO CONSUMPTION AS RISK FACTORS OF LUNG CANCER

10:30 Coffee break

10:45-11:30 SESSION III – Poster highlights

Guided walk and discussions in the poster room

Chairperson: Þórdís Jónsdóttir

(co-chair: Hans Storm)

Deependra Singh: FALSE-POSITIVE RESULTS IN RELATION TO BREAST SYMPTOMS IN FINNISH MAMMOGRAPHY SCREENING PROGRAM

Lovísa Kristín Sigurjónsdóttir: AN ESTIMATION OF COMPLETENESS IN NORDIC CANCER REGISTRIES

Sushmita Katuwal: CASE CONTROL STUDIES ON RISK FACTORS OF BREAST CANCER

Viivi Seppänen: INDUCED ABORTIONS IN FINNISH CHILDHOOD CANCER SURVIVORS

11:45 Lunch (restaurant)

12.50-14:50 SESSION IV – Screening

Chairperson: Anne Mohr Drewes (co-chair: Solveig Hofvind)

Maiju Pankakoski: CUMULATIVE PROBABILITY OF ABNORMALITIES IN ORGANIZED CERVICAL CANCER SCREENING

Petra Makkonen: EFFECT OF ORGANIZED SCREENING AND OPPORTUNISTIC TESTING IN CERVICAL CANCER IN FINLAND AMONG YOUNG WOMEN

Nataliia Moshina: MAMMOGRAPHIC DENSITY AND PERFORMANCE MEASURES IN THE NORWEGIAN BREAST CANCER SCREENING PROGRAM

Gunvor Gipling Waade: COMPRESSION FORCE USED IN THE NORWEGIAN BREAST CANCER SCREENING PROGRAM

Linda Werner Hartman: RISK-REDUCING SURGERY AND CANCER INCIDENCE IN A BRCA1/2-POSITIVE COHORT IN SWEDEN

Þórdís Jónsdóttir: ATTITUDES OF ICELANDIC WOMEN TOWARDS GENETIC COUNSELING AND GENETIC TESTING REGARDING HEREDITARY CANCER

14:50 Coffee break

15:30 Multicultural deeply scientific discussions & outdoor games

Main organiser: Ivalu Katajavaara Sørensen

18:00 Dinner (Mikontalo, built 1892)

20:00 SAUNA SESSION – (river shore sauna)

Sauna, ice-hole swimming, sauna disco, fire place sausages

SUNDAY, 31 January

8.50 Breakfast (restaurant)

9:20-10:50 SESSION V – Events after cancer diagnosis

Chairperson: Linda Hartman (co-chair: Esa Läärä)

Annemarie Brusen Jensen: VENOUS THROMBOEMBOLISM IN SMALL CELL LUNG CANCER

Anne M. Drewes & Maria E. Møller: RISK OF GETTING A SECOND PRIMARY BRAIN TUMOUR IN A PRIMARY BREAST CANCER POPULATION (20 min)

Melanie Poganitsch: PROBABILITY OF FATHERHOOD AND MARRIAGE STATUS AFTER CHILDHOOD CANCER

Mette Vestergaard Jensen: ENDOCRINE LATE EFFECTS IN SURVIVORS OF ADOLESCENT AND YOUNG ADULT CANCER: A DANISH POPULATION-BASED COHORT STUDY

11:00 Lunch

11:30 CLOSURE SESSION

Esa Läärä: Guidelines for article writing

Eero Pukkala: How to submit a paper and get it published: what happens the journal editorial process

Hans Storm: Future of cancer epidemiology

Certificates and closing remarks

Packing, leaving the rooms

13:00 Bus leaves towards Tampere. Stops at Railway Station at 14:45, then makes city sightseeing and finally reaches Tampere Airport at about 16.

ABSTRACTS

(in alphabetical order according to the first name)

CANCER INCIDENCE AND USE OF GEOTHERMAL HOT WATER FOR HEATING AND BATHING

Adalbjorg Kristbjornsdottir, MPH, Centre of Public Health Sciences, University of Iceland, Stapi, Reykjavik, Iceland.

Vilhjalmur Rafnsson, MD, Department of Preventive Medicine, University of Iceland, Stapi Hringbraut, Reykjavik, Iceland.

Background: Residents of geothermal areas have increased incidence and excess mortality of non-Hodgkin’s lymphoma, breast, prostate, and kidney cancers. These populations are exposed to chronic low level ground gas emissions and various pollutants from the geothermal hot water. The aim was to assess whether utilization of geothermal hot water is associated with risk of cancer according to length of residence.

Methods: Those 5-64 years of age were obtained from the census 1981 and followed through 1981-2013. Personal identifier was used in record linkage with nation-wide emigration, death and cancer registries. The exposed population was defined as inhabitants of communities with geothermal hot-water supply systems since 1972. Reference populations were defined according to different degree of volcanic/geothermal activity. Hazard ratio (HR), 95% confidence intervals (CI), without and with stratification on cumulative years of residence, was estimated in Cox-model.

Results: Adjusted HRs for all cancer was 1.17 (95%CI 1.09-1.26) without stratification on residence and 1.21 (95%CI 1.12-1.30) with stratification. Analyses of corresponding HRs for breast cancer was 1.42 (1.18-1.72) and 1.49 (1.23-1.80); for prostate cancer 1.43 (1.19-1.72); and 1.48 (1.23-1.78), and for lymphoid and haematopoietic tissue 1.49 (1.17-1.91), and 1.55 (1.21-1.98). These patterns of positive dose-response relationship were observed between all incidences of cancers and length of residence.

Conclusion: The increased cancer incidence is consistent with previous findings in geothermal area. Positive dose-response relationship between incidence of cancers, length of residence, and gradient of geothermal/volcanic activity need urgent consideration. More information on water and air pollution is needed in further studies.

Title: RISK OF GETTING A SECOND PRIMARY BRAIN TUMOUR IN A PRIMARY BREAST CANCER POPULATION

Authors: Anne M. Drewes1, Maria E. Møller2, Gerda Engholm3, Rasmus Hertzum-Larsen3 & Hans Storm3

1. University of Aarhus, Aarhus, Denmark, 2. University of Copenhagen, Denmark, 3. The Danish Cancer Society, Denmark.

Affiliation: The Danish Cancer Society, Copenhagen, Denmark.

Introduction: In the USA, a trend indicated that women under the age of 40, who have had a primary breast cancer, have an increased risk of a new primary tumour within the brain. On the contrary, a protecting effect was observed in women over the age of 50 years with a previous history of breast cancer. This is likely due to a different hormonal status with a lower oestrogen level in postmenopausal women.

Purpose: In a primary breast cancer population in Denmark, the aim of this study were to compare premenopausal women ( ................
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