Dove Medical Press



Supplementary Material TABLE S1, S2, S3

Supplementary Material TABLE S1. Microbiologic identification for XueBiJing group vs placebo group using descriptive statistics for the intention-to-treat populations

| |Elderly ≥65 |Nonelderly＜65 |

|Characteristics |

|Characteristics |Elderly ≥65 |Nonelderly＜65 |

| |Placebo Group |

|Day 4 |

|Day 4 |5.3 (2.88) |

|Day 4 |

|Day 4 |

|Day 4 |

|Day 4 |

|Day 4 |

|Day 4 |

|Day 4 |65.2 (61.37) |

|Day 4 |

|Day 4 |2.0 (1.08) |1.6 (1.11) |

| |Placebo Group |XBJ Group |Placebo Group |XBJ Group |

|Clinically Significant Laboratory Abnormalities |64 (43.54) |55 (38.19) |68 (37.78) |61 (33.89) |

|Elevated alanine aminotransferase |18 (12.24) |12 ( 8.33) |12 ( 6.67) |18 (10.00) |

|Elevated aspartate amino transferase |13 ( 8.84) |11 ( 7.64) |5 ( 2.78) |10 ( 5.56) |

|Elevated blood urea nitrogen |8 ( 5.44) |12 ( 8.33) |11 ( 6.11) |8 ( 4.44) |

|Elevated glucose |8 ( 5.44) |7 ( 4.86) |7 ( 3.89) |11 ( 6.11) |

|Low red blood cell count |6 ( 4.08) |8 ( 5.56) |10 ( 5.56) |13 ( 7.22) |

|High white blood cell count |6 ( 4.08) |6 ( 4.17) |8 ( 4.44) |10 ( 5.56) |

|Elevated total bilirubin |8 ( 5.44) |4 ( 2.78) |4 ( 2.22) |5 ( 2.78) |

|Elevated serum creatinine |6 ( 4.08) |5 ( 3.47) |4 ( 2.22) |2 ( 1.11) |

|Elevated prothrombin time |6 ( 4.08) |3 ( 2.08) |5 ( 2.78) |1 ( 0.56) |

|Elevated plasma fibrinogen |6 ( 4.08) |3 ( 2.08) |7 ( 3.89) |4 ( 2.22) |

| Low white blood cell count |4 ( 2.72) |4 ( 2.78) |2 ( 1.11) |1 ( 0.56) |

|Elevated activated partial thromboplastin time |5 ( 3.40) |1 ( 0.69) |3 ( 1.67) |2 ( 1.11) |

|Low hemoglobin count |4 ( 2.72) |1 ( 0.69) |7 ( 3.89) |1 ( 0.56) |

|High platelet count |3 ( 2.04) |2 ( 1.39) |4 ( 2.22) |3 ( 1.67) |

|Decreased K+ |1 ( 0.68) |3 ( 2.08) |10 ( 5.56) |4 ( 2.22) |

|Elevated Na+ |2 ( 1.36) |2 ( 1.39) |3 ( 1.67) |2 ( 1.11) |

|Decreased Na+ |2 ( 1.36) |2 ( 1.39) |2 ( 1.11) |0 ( 0.00) |

|Elevated fibrin D-dimer |3 ( 2.04) |1 ( 0.69) |3 ( 1.67) |4 ( 2.22) |

|Decreased serum creatinine |2 ( 1.36) |2 ( 1.39) |5 ( 2.78) |3 ( 1.67) |

|Low white blood cell count |1 ( 0.68) |2 ( 1.39) |2 ( 1.11) |1 ( 0.56) |

|Elevated K+ |1 ( 0.68) |2 ( 1.39) |/ |/ |

|High urine white blood cell count |2 ( 1.36) |1 ( 0.69) |1 ( 0.56) |2 ( 1.11) |

|Positive protein in urine |1 ( 0.68) |2 ( 1.39) |0 ( 0.00) |1 ( 0.56) |

|High urine red blood cell count |2 ( 1.36) |1 ( 0.69) |1 ( 0.56) |2 ( 1.11) |

|Elevated urine glucose |3 ( 2.04) |0 ( 0.00) |1 ( 0.56) |2 ( 1.11) |

|Decreased AST |1 ( 0.68) |2 ( 1.39) |0 ( 0.00) |1 ( 0.56) |

|Decreased blood urea nitrogen |2 ( 1.36) |1 ( 0.69) |/ |/ |

|Abnormal alanine aminotransferase |2 ( 1.36) |0 ( 0.00) |/ |/ |

|High red blood cell count |2 ( 1.36) |0 ( 0.00) |1 ( 0.56) |1 ( 0.56) |

|Decreased plasma fibrinogen |1 ( 0.68) |1 ( 0.69) |2 ( 1.11) |1 ( 0.56) |

|Decreased total bilirubin |0 ( 0.00) |2 ( 1.39) |1 ( 0.56) |0 ( 0.00) |

|Positive fecal occult blood test |/ |/ |1 ( 0.56) |0 ( 0.00) |

| Elevated C reactive protein |1 ( 0.68) |0 ( 0.00) |/ |/ |

|Decreased activated partial thromboplastin time |1 ( 0.68) |0 ( 0.00) |/ |/ |

|Elevated procalcitonin |1 ( 0.68) |0 ( 0.00) |/ |/ |

|Decreased prothrombin time |0 ( 0.00) |1 ( 0.69) |/ |/ |

|High hemoglobin count |1 ( 0.68) |0 ( 0.00) |/ |/ |

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