Title: Gastroesophageal Reflux Disease

Common side effects include: diarrhea, constipation, abdominal pain and headache. In addition long-term PPIs may result in hypergastrinemia, hypochlorhydria and malabsorption. Some evidence suggests that long-term use of PPIs increases the risk of vitamin B-12 deficiency, but there is limited evidence to support this claim11. ................
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