Evidence Report/Technology Assessment

This report is based on research conducted by the University of Ottawa Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (Contract No. 290-02-0021). The findings and conclusions in this document are those of the author(s), who are responsible for its content, and do not necessarily represent the views of AHRQ. No statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.

The information in this report is intended to help clinicians, employers, policymakers, and others make informed decisions about the provision of health care services. This report is intended as a reference and not as a substitute for clinical judgment.

This report may be used, in whole or in part, as the basis for the development of clinical practice guidelines and other quality enhancement tools, or as a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied.

Evidence Report/Technology Assessment

Number 171

Diagnosis and Treatment of Erectile Dysfunction

Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road Rockville, MD 20850

Contract No. 290-02-0021

Prepared by:

University of Ottawa Evidence-based Practice Center, Ottawa, Canada

Investigators Alexander Tsertsvadze, M.D., M.Sc.

Fatemeh Yazdi, M.Sc.

Howard A. Fink, M.D., Ph.D.

Roderick MacDonald, M.S.

Tim J.Wilt, M.D.

Karla Soares-Weiser, M.D., Ph.D.

Anthony J. Bella, M.D.

Dan Deforge, M.D.

Chantelle Garritty, M.Sc.(c)

Mohammed Ansari, M.D., M.Sc.

Margaret Sampson, M.L.I.S.

Raymond Daniel, B.A.

David Moher, Ph.D.

AHRQ Publication No. 08(09)-E016 May 2009

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This document is in the public domain and may be used and reprinted without permission except those copyrighted materials noted for which further reproduction is prohibited without the specific permission of copyright holders. Suggested Citation: Tsertsvadze A, Yazdi F, Fink HA, MacDonald R, Wilt TJ, Soares-Weiser K, Bella AJ, Deforge D, Garritty C, Ansari M, Sampson M, Daniel R, Moher D. Diagnosis and Treatment of Erectile Dysfunction. Evidence Report/Technology Assessment No.171 (Prepared by the University of Ottawa Evidence-based Practice Centre (UO-EPC) under Contract No. 290-02-0021). AHRQ Publication No. 08(09)-E016, Rockville, MD: Agency for Healthcare Research and Quality. May 2009.

No investigators have any affiliations or financial involvement (e.g. employment, consultancies, honoraria, stock options, expert testimony, grants or patents received or pending, or royalties) that conflict with material presented in this report.

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Preface

The Agency for Healthcare Research and Quality (AHRQ), through its Evidence-Based Practice Centers (EPCs), sponsors the development of evidence reports and technology assessments to assist public- and private-sector organizations in their efforts to improve the quality of health care in the United States. The American College of Physicians requested and provided funding for this report. The reports and assessments provide organizations with comprehensive, science-based information on common, costly medical conditions and new health care technologies. The EPCs systematically review the relevant scientific literature on topics assigned to them by AHRQ and conduct additional analyses when appropriate prior to developing their reports and assessments.

To bring the broadest range of experts into the development of evidence reports and health technology assessments, AHRQ encourages the EPCs to form partnerships and enter into collaborations with other medical and research organizations. The EPCs work with these partner organizations to ensure that the evidence reports and technology assessments they produce will become building blocks for health care quality improvement projects throughout the Nation. The reports undergo peer review prior to their release.

AHRQ expects that the EPC evidence reports and technology assessments will inform individual health plans, providers, and purchasers as well as the health care system as a whole by providing important information to help improve health care quality.

We welcome comments on this evidence report. They may be sent by mail to the Task Order Officer named below at: Agency for Healthcare Research and Quality, 540 Gaither Road, Rockville, MD 20850, or by e-mail to epc@.

Carolyn M. Clancy, M.D. Director Agency for Healthcare Research and Quality

Jean Slutsky, P.A., M.S.P.H. Director, Center for Outcomes and Evidence Agency for Healthcare Research and Quality

David C. Dale, M.D., F.A.C.P. President American College of Physicians

Beth A. Collins Sharp, Ph.D. Acting Director, EPC Program Agency for Healthcare Research and Quality

Steven Fox, M.D., M.P.H. EPC Program Task Order Officer Agency for Healthcare Research and Quality

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Acknowledgments

The authors would like to thank numerous individuals for their support of the present project. Investigators thank Nathalie Lapierre, Gloria Baker, and Dorothey Ann Curran for their assistance with screening articles and helping with data abstraction; David Mackie and Mary Ocampo for helping with the evidence tables and appendices; and Tanya Horsley and Kasey Parker, both of whom helped to coordinate the process. Investigators would also like to thank Anne Marie Todkill, who assisted in the editing of the report.

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