Science - perry.k12.ia.us
BiotechnologyStandard 1: What is BiotechnologyLearning Target 1.1: Describe the science of biotechnology and identify its product domains. Learning Target 1.2: Give examples of careers and job responsibilities associated with biotechnology.Learning Target 1.3: Outline steps in producing and delivering a product made through recombinant DNA technology.Learning Target 1.4: Describe how scientific methodologies are used to conduct experiments and develop products.Learning Target 1.5: Apply the strategy for values clarification to bioethical issues.Standard 2: The Raw Materials of BiotechnologyLearning Target 2.1: Identify the levels of biological organization and explain their relationships.Learning Target 2.2: Discuss the types of organisms researched and the types of cells grown and studied in biotechnology facilities.Learning Target 2.3: List the four main classes of macromolecules and describe their structure and function.Learning Target 2.4: Define genetic engineering an identify products created with this technology.Learning Target 2.5: Explain the Central Dogma of Biology and its importance in genetic engineering.Standard 3: The Basic Skills of the Biotechnology WorkplaceLearning Target 3.1: Determine the most appropriate tool for measuring specific volumes or masses.Learning Target 3.2: Describe how to select, set, and use a variety of micropipets within their designated ranges to accurately measure small volumes.Learning Target 3.3: Recognize the different expressions for units of concentration measurements and use their corresponding equations to calculate the amount of solute needed to make a specific solution. Learning Target 3.4: Convert between units of measurement using the B S rule and appropriate conversion factors.Learning Target 3.5: Define the term buffer and calculate a specified dilution from a concentrated stock solution or buffer.Standard 4: Introduction to Studying DNALearning Target 4.1: Describe the structure and function of DNA and explain the process by which it encodes for proteins.Learning Target 4.2: Differentiate between eukaryotic and prokaryotic chromosomal structure and explain how this difference impacts gene regulation in the two cell types.Learning Target 4.3: Discuss the characteristics of viruses and their importance in genetic engineering.Learning Target 4.4: Explain the fundamental process of genetic engineering and give examples of the following applications: recombinant DNA technology, site-specific mutagenesis, and gene therapy.Learning Target 4.5: Describe the process of gel electrophoresis and discuss how the characteristics of molecules affect the migration though a gel.Biotechnology continuedStandard 5: Introduction to Studying Proteins.Learning Target 5.1: Describe the structure of proteins, including the significance of amino acid R-groups and their impact on the three-dimensional structure of proteins.Learning Target 5.2: Explain the steps of transcription and translation in protein synthesis.Learning Target 5.3: Differentiate proteins that function as part of structure, as antibodies, and as enzymes.Learning Target 5.4: Discriminate among the classes of enzymes and discuss the effect of reaction conditions on enzyme activity.Learning Target 5.5: Summarize polyacrylamide gel electrophoresis and identify its usefulness for studying proteins.Standard 6: Identifying a Potential Biotechnology ProductLearning Target 6.1: Give examples of biotechnology products derived from plant and animal sources and discuss the challenges of extracting compounds from plants as well as the strategies for overcoming them.Learning Target 6.2: Explain how scientists test the effectiveness of antibiotics and antimicrobials and discuss the significance of antibiotic resistance.Learning Target 6.3: Identify the steps in a Comprehensive Product Development Plan and use it to determine whether a potential biotechnology product is worth manufacturing.Learning Target 6.4: Discuss the types of assays done as potential products move through process development and identify the additional assays required for pharmaceutical development.Learning Target 6.5: Describe the typical recombinant DNA protein product pipeline, additional steps required by the FDA for pharmaceutical proteins, and possible formulations of the final product. ................
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