Renal Dosing of Common Oral Antibiotics Updated 1/18/2019 ...

Renal Dosing of Common Oral Antibiotics

Updated 1/18/2019 Page 1

Generic Name [Brand] Macrolides Azithromycin [Zithromax, Zmax] Clarithromycin

Adult Dosing

250-500 mg/day ER* suspension: 2g as single dose 250-500 mg every 12 hours

[Biaxin, Biaxin XL]

ER* two 500mg tablets

Erythromycin [E.E.S., Ery- 500-800 mg every 6-12 hours Tab, Erythrocin, Romycin]

Penicillins Ampicillin [Apo-Ampi, 250-500mg every 6 hours Novo-Ampicillin, Nu-Ampi]

Amoxicillin [Amoxil]

500mg to 1g every 8-12 hours

Amoxicillin ER

ER*: 775mg daily

Amoxicillin/Clavulanate 250-500 mg every 8 hours or 875 mg

[Augmentin,

every 12 hours

Augmentin XR]

ER*: 2g every 12 hours

Penicillin VK [ApoPen VK] 125-500mg every 6-8 hours

Tetracyclines

Doxycycline [Adoxa,Doryx, Oral, IV: 100-200 mg/day in 1-2 Monodox, Vibramycin] divided doses

Minocycline [Dynacin, Minocin PAC]

200 mg followed by 100 mg every 12 hours (max 400 mg/day)

Tetracycline [ApoTetra, Nu-Tetra]

250-500 mg every 6 hours

1st Generation Cephalosporins

Cefadroxil [Duricef]

250-1000 mg every 8-12 hours

Cephalexin [Keflex]

250-1000 mg every 6-12 hours (max 4

g/day)

UTI: 500mg every 12 hours

2nd Generation Cephalosporins

Cefaclor [Raniclor]

250-500 mg every 8 hours

Renal Adjusted Dose

Use caution in patients with CrCl ................
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