New Zealand Practice Guidelines for Opioid Substitution ...

Omeprazole reduces noxious effects of reflux via its actions as a proton pump inhibitor. Ranitidine can be used as second line, but can give problems with rebound nocturnal acid secretion. ... This should be encouraged as this will help to wean the patient off ventilation for periods of time, this will also help with feeding, communication etc. ... ................
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