Weill Cornell Medical College



Weill Cornell Medical College Curriculum Vitae FORMGENERAL INFORMATIONRequired Information:Name: First, Middle, LastMonica Girotra, M.D.Office address:Memorial Sloan-Kettering Cancer Center1275 York Avenue, New York NY 10065 Office telephone:646-888-2712Office fax:646-888-2737EDUCATIONAL BACKGROUNDAcademic Degree(s): B.A. and higher; institution name and location; dates attended; date of award. Expand the table as needed.Degree(abbreviation)Institution Name and LocationDates attendedYear AwardedB.S. with distinction BiopsychologyCornell UniversityIthaca, NY1991-19951995MD with honors in research Weill Cornell Medical CollegeNew York, NY1995-20002000Post-doctoral training (include residency/fellowships): In chronological order beginning with post-doctoral training positions; include full titles, ranks and inclusive dates held. Expand the tables as needed.TitleInstitution name and locationDates held Internal Medicine ResidencyNew York-Presbyterian Hospital/ Cornell Medical Center; New York, NY2000-20003Endocrinology Fellowship (Clinical & Research Fellow under NIH training grant)New York-Presbyterian Hospital/ Columbia Presbyterian Medical Center; New York, NY2003-2006Continuing Medical Education Courses/CertificatesCertificate or Course Institution Name and LocationDates attendedEndocrine Grand RoundsMemorial Sloan-Kettering Cancer CenterNew York NY2007- presentPituitary & Skull Base Tumor Board ConferenceMemorial Sloan-Kettering Cancer CenterNew York NY2014- presentEndocrine Society Annual MeetingBoston, MA4/2016Fourteenth International Pituitary CongressSan Diego, CA4/2015Board CertificationFull Name of BoardCertificate #Dates of Certification (mm/dd/yyyy) – Start and End DatesAmerican Board of Internal Medicine8/13/03-12/31/13Endocrinology, Diabetes, & Metabolism10/28/05-presentPROFESSIONAL POSITIONS AND EMPLOYMENTAcademic positions (teaching and research)TitleInstitution name and locationDates heldAssistant Professor of MedicineUniversity of Medicine & Dentistry of NJ, NJ Medical School, Newark, NJ2006-2007Assistant Clinical MemberMemorial Sloan Kettering Cancer CenterNew York, NY2007- 2014Assistant Professor of Clinical MedicineWeill Cornell Medical CollegeNew York, NY2007-Associate Clinical MemberMemorial Sloan Kettering Cancer CenterNew York, NY2015 -Hospital positions (e.g., attending physician)TitleInstitution name and locationDates heldAssistant Attending PhysicianUniversity of Medicine & Dentistry of New Jersey University Hospital, Newark, NJ2006-2007Assistant Attending PhysicianMemorial Hospital for Cancer & Allied Diseases, NY, NY2007- 2014Assistant Attending PhysicianMemorial Hospital for Cancer & Allied Diseases, NY, NY2015 -Other EmploymentTitleInstitution name and locationDates heldHealth Promotion and Disease Prevention FellowThe National Health Service Corps and the American Medical Student Association5/96-8/96Molecular Medicine Research FellowWeill Cornell Medical CollegeNew York, NY1/99-1/00International Fellow, India(provision of medical care in impoverished rural and urban communities) Weill Cornell Medical College & New York-Presbyterian Hospital/Weill Cornell Medical CenterNY, NY (sponsored)5/00-6/00 & 11-12/03EMPLOYMENT STATUS (current )Name of Employer(s): Memorial Sloan Kettering Cancer CenterINSTITUTIONAL/HOSPITAL AFFILIATION1. Primary Hospital Affiliation:Memorial Hospital for Cancer and Allied Diseases3. Other Institutional Affiliations:Weill Cornell Medical College INSTITUTIONAL RESPONSIBILITIESTeaching (e.g., specific teaching functions, courses taught, dates:Didactic teaching: (e.g., lectures, continuing medical education courses, grand rounds, professional development programs, seminars, tutorials)Lectures on Pituitary Adenomas/Imaging for MSKCC and Weill Cornell Endocrine fellows, residents, medical students and MSK RNsMSKCC & NYPH/WCMC Endocrinology ServiceFellows and Resident Endocrine Emergency Lecture Series:Pituitary Apoplexy Mentorship: (e.g., mentor for medical student, graduate student, resident, clinical or postdoctoral research fellow or junior faculty projects; service as graduate student thesis advisor or committee member)Clinical and Research mentor for Anna Gorelick, MD (MSK Internal Medicine Resident): Examining the psychiatric side effects of dopamine agonist therapy for hyperprolactinemia Clinical mentor for medical students Anam Khan (1/2010); Carole Douriez (4/2011); Taha Al-Juhaishi Weill Cornell Medical College -Qatar (5/2013)Mentor for Jane Meisel, MD MSKCC oncology fellow during preparation for chapters on Sellar Tumors & Pheochromocytoma/Multiple Endocrine Neoplasia for Pocket Oncology. In press. Lippincott Williams & Wilkins.Research mentor for 2nd year joint MSKCC & NYPH/WCMC Endocrine fellow: Developed a retrospective protocol to examine changes in trabecular bone score (a measurement of bone microarchitecture derived from DXA) in women with breast cancer before and after aromatase inhibitor therapy Research mentor for 1st year joint MSKCC & NYPH/WCMC Endocrine fellow: Clinical Presentation and Outcomes of Patients with Metastatic Disease to the Sella Research mentor for Weill Cornell Medical College medical student: Clinical Presentation and Outcomes of Patients with Metastatic Disease to the Sella Research mentor for Weill Cornell Medical College medical student and MSK/WMC Endocrine fellows examining immunotherapy-induced endocrine dysfunction Dates20102010-20131/2013-7/2013 & 11-12/20176/2013-6/20143/2014-6/20152015-present7/2014- presentClinical teaching: (e.g., teaching in the clinic or hospital including bedside teaching, teaching in the operating room, preceptor in clinic)Teach MSKCC and Weill Cornell fellows, residents, and medical students during endocrine outpatient clinic, inpatient rotations, and divisional conferencesAdvances in the Care of Acromegaly: Endocrine Grand Rounds, MSKCC/ Weill Cornell Medical CollegeDates9/07— present4/2014Administrative teaching leadership role: (e.g., residency or fellowship director,course or seminar director or co-director)PBL facilitator for Human Structure and Function, Weill Cornell Medical CollegeOral Examiner: Human Structure and Function Exam,Weill Cornell Medical College Reviewed Written Exams: Human Structure and Function Course, Weill Cornell Medical College Medical Housestaff Conference: Multiple Endocrine Neoplasia, MSKCCWeill Medical College of Cornell University, Endocrine Grand Rounds: Weight Loss, Leptin, and Bone Mineral Metabolism Continuing Education Program for MSK Nurses: Endocrine Effects of CanerCaring for Cancer Survivors: Managing Late Effects of Cancer Treatment seminar Cancer Treatment Effects on the Thyroid Gland, MSKCCOffice of Graduate Medical Education and Office of Diversity Programs in Clinical Care, Research and Training: faculty sponsor in the 2010 Summer Fellowship Program for visiting student, MSKCC Internal Medicine Morning Report MSKCC: Metastatic PheochromocytomaPituitary and Skull Base Tumor ConferenceMultidisciplinary conference with neurosurgery, neuroradiology, ophthalmology, and radiation oncology presenting challenging cases and literature review; a component of NYPH-WCMC/MSKCC joint Endocrinology Fellowship Core Curriculum Conferences with MSK/Weill Cornell fellows & medical studentsIntroduction to Medicine Course, Weill Cornell Medical College. Inpatient Session leader guiding students on presenting inpatient cases and preparing admission and progress notes with Weill Cornell Medical StudentsIntroduction to Medicine Course, Weill Cornell Medical College. Small Group Clinical Case Session leader with Weill Cornell Medical StudentsEssential Principles of Medicine, Weill Cornell Medical College, Small Group Session LeaderIntroductory Clerkship, Weill Cornell Medical College, Small Group Session Leader on chest pain,?abdominal pain, dyspnea, and mental status changes.Dates2/08-4/084/084/086/0810/0812/084/097/10-9/104/201112/2013—6/20146/201411/2014-12/20144/2015Clinical care (duties, dates: To document clinical activities use the table below or, to document extensive clinical activities use the Clinical Portfolio template (strongly encouraged). Refer to it here as an attachment and attach it to the CV.Outpatient Endocrinology PracticeSpecialized care to patients with pituitary disorders, metabolic bone disease, adrenal masses/disorders, thyroid cancer, endocrine complications of cancer/cancer treatment and general endocrine conditionsInpatient Endocrinology Consult Service, 2-3 months/yearInpatient treatment of endocrine disorders and endocrine complications of cancer/cancer treatment, for example immunotherapy-induced hypophysitis, steroid-induced hyperglycemia, thyroid cancer treatment with radioactive iodine Pituitary and Skull Base Tumor BoardMonthly multidisciplinary clinical case conference with neurosurgery, neuroradiology, ophthalmology, and radiation oncology to provide a comprehensive multidisciplinary approach to patient care.9/07- present9/07- present12/2016- presentResearch (duties, dates):.Research Activity / Key ContributionsDatesCost-effectiveness of fracture prevention in men who receive androgen deprivation therapy for localized prostate cancer. Co-Investigator; PI Kouta Ito Determining the effect of weight loss and subsequent leptin administration (to restore leptin levels to baseline concentrations before weight loss) on bone mineral metabolism in obese and lean individuals. Co-PI; PI Judith Korner Presentations and Outcomes of Metastatic lesions to the SellaPI, Endocrine Dysfunction assoicated with the CTLA-4-blocking antibody ipilimumab and PD-1 or PD-L1–blocking antibodies during the treatment of malignancy. PI An Open Label, Multi-center Pasireotide Roll-over Protocol For Patients Who Have Completed a Previous Novartis-Sponsored Pasireotide Study and Are Judged By The Investigator To Benefit From Continued Pasireotide Treatment.Co-PI A Phase III, MultiCenter, Double-Blind, Randomized Withdrawal Study of LCI699 Following a 24 Week, Single-Arm, Open-Label Dose Titration and Treatment Period to Evaluate the Safety and Efficacy of LCI699 for the Treatment of Patients with Cushing's DiseaseCo-PI An Open Label Study to Assess the Safety and Efficacy of COR-003 (2S, 4RKetoconazole) in the Treatment of Endogenous Cushing's SyndromeCo-PI 2/2009-5/20108/2004-2/20111/2014-6/2014-9/2016 -9/2016 –11/2016-Administrative Activities (duties, dates): Administrative ActivityDateDeveloping the Pituitary Program and Conferences at MSKCC: developing the MSK pituitary program website and revising educational/background materials regarding pituitary tumors/hormonal presentations; structuring triage system for visits and clinical care including coordination of care with neurosurgery, radiation oncology, neuroradiology, WCMC neuro-ophthalmology; planning/organization of multidisciplinary hospital-wide Pituitary and Skull Base Tumor Board Reviewed and /revised Bisphosphonate and& Osteonecrosis of the Jaw Patient Fact Card Revised Nursing Protocol for Cosyntropin Stimulation Testing.Multidisciplinary Committee to Improve Bone Health and Muscle Function in Stem Cell Transplant Patients (Members include individuals from the BMT Service, Endocrine, Gynecology, Physical Therapy, and Quality Assessment Department.)Joint Weill Cornell/MSK/HSS Endocrine Grand Rounds Organization CommitteeCaring for Cancer Survivors: Cancer Treatment Effects on the Thyroid GlandPresentation posted on MSKCC websiteAdult Bone Marrow Transplant Survivorship Working Group (Members include individuals from the BMT, Endocrine, Renal, Pulmonary, Gynecology, Infectious Disease, Cardiology. Dermatology, Physical Therapy Services) Goal is to optimize their post-transplant medical careMSK Committee for the development of the MSKCC adrenal tumor program with surgery, oncology, radiology; development of patient-centerededucational/background materials on adrenal tumors/hormonal presentations on the MSK websiteDevelopment of pituitary clinical visit forms (to be used to assess new and follow-up patients)Development and implementation of a Quest interface for endocrine labs done at outside Quest facilities to be uploaded directly into MSK’s clinical information system.Develop and revise materials on adrenal insufficiency for our patients and RNs; resources utilized by other services as well as inpatient staff.Development and updating of patient educational materials regarding calcium supplementation/osteoporosisCase reviewer for the MSKCC Department of Medicine Quality Assurance CommitteeUpdated/ and revised MSKCC online/PDF resource: Osteonecrosis of the Jaw resourceDevelopment of guidelines for hormonal monitoring after immunotherapy for cancer treatmentMultidisciplinary Immunotherapy Adverse Event Management Team, MSKCC9/079/0712/072008-20109/08-9/094/098/09201020102010201020104/201311/20137/201412/2015EXTRAMURAL PROFESSIONAL RESPONSIBILITIESi.e. - Journal Reviewer, Editorial Boards, Study Sections, Invited PresentationsActivity / Responsibility National Activities:The Pituitary Society, Digital Communications and Website Design CommitteeLead endocrinologist in the National Cancer Institute Investigational Drug Steering Committee (IDSC) Working Group examining the Endocrine Effects from ImmunotherapyInvited lectures:Cancer Immunotherapy-Induced Autoimmune Diabetes and Endocrinopathies—The Memorial Sloan-Kettering Cancer Center Experience. American Diabetes Association 78th Scientific Sessions. Orlando, FL June 2018An Overview of Autoimmune-Related Endocrinopathies Associated with Cancer Immunotherapy. National Cancer Institute Conference on Cancer, Autoimmunity, and Immunology. NIH Campus. March 2018Endocrinopathies Associated With Immune Checkpoint Inhibitors. MSK 2018 Annual Cancer Treatment-Related Adverse Events Symposium. NY, NY. October 2018. Endocrinopathies Associated With Immune Checkpoint Inhibitors. Medical Grand Rounds. MSKCC. NY, NY. February 2019Endocrinopathies Associated With Immune Checkpoint Inhibitors. MSK Immunotherapeutics Conference. NY, NY. September 2018. Endocrinopathies associated with immunotherapy. 35th National Congress of the Mexican Society of Oncology (SMeO). México. October 2017. CA209-915 Presentation at Investigator Meeting. Bristol-Myers Squibb. Title: Immune Checkpoint Blockade and Associated EndocrinopathiesMSKCC Regional-wide Presentation Title: Immune Checkpoint Blockade and Associated Endocrinopathies 2017 and 2018. Presentation for BMS TV Title: Management of Endocrine Events with the Nivolumab + Ipilimumab Combination in Advanced Melanoma 2017.Location: Advanced Melanoma Advisory Board Meeting on best practices in managing immune-mediated adverse events for the nivolumab and ipilimumab combination regimen. Bristol-Myers Squibb. Title: Immune Checkpoint Blockade and Associated Endocrinopathies 2017.Advances in the Care of Acromegaly. Endocrine Grand Rounds, St. Luke’s-Roosevelt Hospital, NY, NY, Journal Review:Endocrine-Related CancerThe Medical LetterPROFESSIONAL MEMBERSHIPSInclude medical and scientific societies.Member/Officer/Fellow/RoleOrganizationDatesMemberEndocrine Society10/2000– -6858038163500MemberMemberAmerican Society of Bone & Mineral ResearchAmerican Society of Bone & Mineral Research01/2010– 12/2010–HONORS AND AWARDSName of awardDate awardedCornell Merrill Presidential Scholar: Undergraduate Award for individual intop 1% in academic standing, leadership, and community service1995National Health Service Corps & AMA Health Promotion and Disease Prevention Summer Grant1996Molecular Medicine Research Fellowship, Weill Cornell Medical College1999The Dean William Mecklenburg Polk Research Prize2000The Endocrine Society Medical Student Achievement Award2000Swanson Fellow in Diabetes at Columbia P&Sto honor strong commitment to patient care and research in diabetes2005BIBLIOGRAPHYPeer-Reviewed Articles 1. Jeremias J, Korneeva I, Girotra M, Caputo T, Witkin SS. Polymorphism in the gene encoding for the inducible 70 kDa heat shock protein (HSP70) and ovarian cancer. Infectious Diseases in Obstetrics and Gynecology. 1999; 7: 121-122.? 2. Korneeva I, Bongiovanni AM, Girotra M, Caputo T, Witkin SS. IgA antibodies to the 27 kDa heat shock in the genital tracts of women with gynecologic cancers. International Journal of Cancer. 2000; 87 (6): 824-828.?3. Korneeva I, Bongiovanni AM, Girotra M, Caputo TA, Witkin SS. Serum Antibodies to the 27 kDa heat shock protein in women with gynecological cancers. American Journal of Obstetrics and Gynecology. 2000; 183 (1):18-21.4. Slomovitz B, Girotra M, Aledo A, Saqi A, Soslow RA, Spigland NA, Caputo TA. Desmoplastic small round cell tumor with primary ovarian involvement: a case report and review. Gynecological Oncology. 2000; 79 (1):124-128.5. Ito K, Elkin MS, Girotra M, Morris MJ. Cost-effectiveness of fracture prevention in men who receive androgen deprivation therapy for localized prostate cancer. Ann Intern Med. 2010 May 18;152(10):621-9.6. Szerlip NJ, Zhang YC, Placantonakis DG, Goldman M, Colevas KB, Rubin DG, Kobylarz EJ, Karimi S, Girotra M, Tabar V. Transsphenoidal resection of sellar tumors using high-field intraoperative magnetic resonance imaging. Skull Base. 2011 Jul;21(4):223-32. 7. Conroy R, Girotra M, Shane E, McMahon DJ, Pavlovich KH, Leibel RL, Rosenbaum M, Korner J. Leptin administration does not prevent the bone mineral metabolism changes induced by weight loss. Metabolism. 2011;60 (9):1222-6.8. Berman E, Girotra M, Cheng C, Chanel S, Maki R, Shelat M, Strauss HW, Fleisher M, Heller G, Farooki A. Effect of long term imatinib on bone in adults with chronic myelogenous leukemia and gastrointestinal stromal tumors. Leuk Res. 2013 Jul;37(7):790-4.9. Erin E. Salo-Mullen, Jinru Shia, Isaac Brownell, Peter Allen, Girotra M, Mark E. Robson, Kenneth Offit, Jose G. Guillem, Arnold J. Markowitz, Zsofia K. Stadler. Mosaic partial deletion of the PTEN gene in a patient with Cowden syndrome. Familial Cancer. 2014 Sep;13(3):459-67.10. Mariotti V, Page DB, Davydov O, Hans D, Hudis CA, Patil S, Kunte S, Girotra M,Farooki A, Fornier MN. Assessing fracture risk in early stage breast cancerpatients treated with aromatase-inhibitors: An enhanced screening approachincorporating trabecular bone score. J Bone Oncol. 2016 Oct 18;7:32-37.Books, book chapters and reviews1. Girotra M, Bluestone J, Herold KC. Chapter 39: Immunologic Mechanisms Causing Autoimmune Endocrine Disease. Endocrinology. Fifth Edition. Editor: DeGroot L. Elsevier. 2005.?? ?2. Girotra M, Rubin MR, Bilezikian JP. Anabolic Agents for Osteoporosis. Treatments in Endocrinology. 2006; 5(6):347-58.?3. Girotra M, Rubin MR, Bilezikian JP. Anabolic skeletal therapy for osteoporosis. Arq Bras Endocrinol Metabol. 2006 Aug;50(4):745-54. ?4. Girotra M, Rubin MR, Bilezikian JP. Use of Parathyroid Hormone in the Treatment of Osteoporosis. Review in Endocrine and Metabolic Disorders. 2006; 7(1-2):113-21.5. Farooki A, Fornier M, Girotra M. Anabolic therapies for osteoporosis [Letter]. N Engl J Med. 2007 Dec 6;357(23):2410.6. Primary Author of the manuscript for The Medical Letter. Treatment Guidelines: Drugs for the Prevention and Treatment of Postmenopausal Osteoporosis. October 2008 (6): 67-74. Invited to devleop and update treatment guidelines for The Medical Letter. 7. Girotra M, Cosman F, Bilezikian JP. Treatment of Male Osteoporosis with Parathyroid Hormone. Osteoporosis in Men. 2nd Edition. 2010. 8. Primary Author of the manuscript for The Medical Letter. Treatment Guidelines: Drugs for the Prevention and Treatment of Postmenopausal Osteoporosis. November 2011 (9). 67-74. Invited to devleop and update treatment guidelines for The Medical Letter.9. Meisel J, Girotra M. De Braganca KC, Kaley TJ. Sellar Tumors. Pocket Oncology. Editors: Drilon A, Postow M. Lippincott Williams & Wilkins. 2014. 10. Meisel J, Girotra M. Pheochromocytoma and Multiple Endocrine Neoplasia. Pocket Oncology. Editors: Drilon A, Postow M. Lippincott Williams & Wilkins. 2014. 11. Alemán JO, Farooki A, Girotra M. Tyrosine kinase inhibition in bone metabolism: untargeted consequences of targeted therapies. Invited Review for Endocrine Related Cancer. 2014 May 8;21(3):R247-59.12. Primary Author of the manuscript for The Medical Letter. Treatment Guidelines: Drugs for the Prevention and Treatment of Postmenopausal Osteoporosis. In press. Invited to devleop and update treatment guidelines for The Medical Letter.13. Byun DJ, Wolchok JD, Rosenberg LM, Girotra M. Cancer immunotherapy - immunecheckpoint blockade and associated endocrinopathies. Nat Rev Endocrinol. 2017 Jan20.14. Girotra M, Hansen A, Farooki A, Byun DJ, Min L, Creelan BC, Callahan MK,Atkins MB, Sharon E, Antonia SJ, West P, Gravell AE; Investigational DrugSteering Committee (IDSC) Immunotherapy Task Force collaboration. The CurrentUnderstanding of the Endocrine Effects From Immune Checkpoint Inhibitors andRecommendations for Management. JNCI Cancer Spectr. 2018 Jul;2(3)Abstracts1. Girotra M, Korner J, Shane E, McMahon D, Heymsfield S, Gallager D, Pavlovich K,? Leibel RL, Rosenbaum M. Maintenance of Reduced Weight is Associated with Decreased Bone Formation and Increased Bone Resorption and Is Not Reversed by Low-Dose Leptin Administration.? The 28th Annual Meeting of the American Society for Bone and Mineral Research 2006 (Poster)2. Crosson JC, Tseng C, Schmittdiel J, Onyemere K, Ross S, Swain B,? Heisler M, Davis G, Girotra M, Lasser N. A typology of primary-care physician styles in diabetes care: results from the Translating Research into Action for Diabetes (TRIAD) Study.? The 35th Annual Meeting of the North American Primary Care Research Group (NAPCRG) 2007.3. Berman E, Maki RG, Farooki A, Girotra M, Chanel S, Cheng C, Strauss W, Fleisher M. Effect of Long term Imatinib on Bone Mineral Density in Patients with Chronic Myelogenous Leukemia (CML) or Gastrointestinal Stromal Tumors (GIST). Abstract presented for American Society of Hematology Annual Meeting 2010.4. Page DB, Mariotti V, Davydov O, Girotra M, Patil S, Hans D, Hudis CA, Farooki A, Fornier MN. A combined screening approach of Fracture Risk Assessment (FRAX) tool and Trabecular Bone Score to identify osteoporotic-range fracture risk in breast cancer patients treated with adjuvant aromatase inhibitor. The American Society of Clinical Oncology Annual Meeting 2015 (Poster).5. Patel KR, Kim, S, Zheng J, Tabar V, Cohen M, Girotra M. Pituitary Metastases: Clinical Features, Management and Outcomes. Poster Presentation. Endocrine Society Annual Meeting 2016. Article in preparation for submission.Presentations1. Girotra M, Korner J, Shane E, McMahon D, Heymsfield S, Gallager D, Pavlovich K,? Leibel RL, Rosenbaum M. Maintenance of Reduced Weight Is Associated with Decreased Bone Formation and Increased Bone Resorption and Is Not Reversed by Low-Dose Leptin Administration. The 88th Annual Meeting of the Endocrine Society 2006 (oral plenary presentation).6. Sinha AG, Zheng J, Girotra M. Pituitary Dysfunction After CTLA-4 Blockade: Time Course and Hypothalamic-Pituitary-Adrenal (HPA) Axis Recovery. Oral Presentation. 100th Annual Meeting of the Endocrine Society. March 17 - March 20, 2018, Chicago. Endocrine Reviews, Volume 39, Issue 2 Supplement, April 2018 ................
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