DILAUDID® ORAL LIQUID and DILAUDID® TABLETS …

Metabolism Hydromorphone is extensively metabolized via glucuronidation in the liver, with greater than 95% of the dose metabolized to hydromorphone-3-glucuronide along with minor amounts of 6-hydroxy reduction metabolites. Elimination Only a small amount of the hydromorphone dose is excreted unchanged in the urine. Most ................
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