Northwestern Medicine Antimicrobial Stewardship
IDSA 2nd Line therapy in patient with underlying co-morbidities and recent antibiotic use. Due to overuse, 50% of all S. pneumoniae is now resistant to PCN. Cephalosporins are structurally similar to PCN and often share this resistance. Use only 2nd and 3rd generation cephalosporins and use only in combination in areas where PCN-resistance exists. ................
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