Abstract - Imperial College London

A fundamental property of many cancers is the ability to avoid the host immune response and allow cell proliferation and metastasis. Harnessing the immune system to target cancer has been a strategy employed in oncology for many decades.1 A major advance in the last 10 years is the use of immune checkpoint inhibitors (ICIs) to block the inhibitory receptors such at cytotoxic lymphocyte ... ................
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