INTRODUCTION .tw

The most commonly targeted checkpoints for cancer immunotherapy are CTLA-4, PD-1, TIM-3 and LAG-3. Ipilimumab (CTLA-4 blocker), nivolumab and pembrolizumab (two PD-1 blockers) and atezolizumab, avelumab and durvalumab (three PD-L1 blockers) are approved for the treatment of different solid tumors such as melanoma, lung cancer, head and neck ... ................
................