LEARN MORE ABOUT 20 MILLION AND ONE



LEARN MORE ABOUT 20 MILLION AND ONE | |

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|Dear valued patient, |

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|We are excited to share with you a new offer on both Restylane* and Dysport® (abobotulinumtoxinA). Restylane is the #1 filler patients rely on with over 20 million treatments |

|received worldwide.1† |

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|Now you have the chance to make it 20 MILLION AND ONE—at a discounted price. |

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|20 MILLION AND ONE |

|starts with you |

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|In celebration of this milestone 20 million treatments, Galderma is offering a new promotion—20 MILLION AND ONE. For a limited time only, you can get a discount off your total |

|treatment cost when you receive both Restylane and Dysport by the end of the year. |

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|Here’s the deal |

|Receive a discount off of the total cost of Restylane and Dysport treatments. Both treatments must be received between October 1 and December 31, 2014 |

|Discount is available via mail-in rebate (proof of purchase required for both products) |

|Promotion runs from October 1 through December 31, 2014 |

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|20 MILLION AND ONE reasons to choose Restylane |

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|Millions of people rely on Restylane. Here’s why you can, too. |

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|• Trusted by millions |

|- 20 million treatments received worldwide1 |

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|• Tailored to you |

|Different gel particle sizes in each Restylane product help achieve your desired results2 |

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|• Natural by design |

|Patented gel technology preserves natural skin structure—delivering consistent lift and support3 |

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|Don’t miss out! |

|Book your 20 MILLION AND ONE |

|appointments today. |

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|See you soon, |

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|Cory Yeh MD |

|Yeh Facial Plastic Surgery |

|*Treatment applies to both Restylane and Perlane. |

|†20 million treatments includes the entire Restylane family of products. |

|References: 1. Data on file, Galderma Laboratories. 2. Öhrlund Å et al. Size and Shape of Gel Particles in Hyaluronic Acid Dermal Fillers. 18th Congress of the European Academy of |

|Dermatology and Venereology (EADV). Berlin, October 7-11, 2009. 3. Edsman K, Nord L, et al. Gel properties of hyaluronic acid dermal fillers. Dermatol Surg. 2012;38:1170-1179. |

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|See Important Safety Information including Distant Spread of Toxin Effect |

|Boxed Warning and full Prescribing Information |

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|Restylane |

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|The Restylane family of products includes Restylane®, Restylane-L®, Perlane®, and Perlane-L®. These products can be used to add volume and fullness to the skin to correct moderate |

|to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds). Restylane and Restylane-L may also be used for lip enhancement|

|in patients over 21 years. Ask your doctor which is right for you. |

|Important Safety Considerations for the Restylane family of products
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|Products in the Restylane family should not be used by people with previous bad allergies, particularly to microorganisms known as gram-positive bacteria, or by people with serious |

|allergies to drugs that have previously required in-hospital treatment. These products should not be used by people with bleeding disorders. Products should not be injected anywhere|

|except the skin, just under the skin (Perlaneand Perlane-L only), or in the lips (Restylane and Restylane-L only). Restylane-L and Perlane-L should not be used by anyone with a |

|known allergy to lidocaine. |

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|Use at the site of skin sores, pimples, rashes, hives, cysts, or infection should be postponed until healing is complete. In these instances, product use could delay healing or make|

|your skin problems worse. After treatment, you might have some swelling, redness, pain, bruising, or tenderness. These are typically mild in severity and normally last less than 7 |

|days in nasolabial folds and less than 14 days in lips. Swelling may be more likely in patients under 36 years, and bruising may be more likely in patients over 35 years. Rarely, |

|the doctor may inject into a blood vessel, which can damage the skin. Although rare, red or swollen small bumps may occur. If you have had facial cold sores before, an injection can|

|cause an outbreak. To avoid bruising and bleeding, you should not use the products if you have recently used drugs that thin your blood or prevent clotting. Products should not be |

|used during pregnancy, when breastfeeding, or in patients under 18 years for nasolabial folds. |

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|Treatment volume should be limited to 6.0 mL in wrinkles and folds, such as nasolabial folds, and limited to 1.5 mL per lip (Restylane and Restylane-L only), as greater amounts |

|significantly increase moderate and severe injection site reactions. The safety or effectiveness of treatment in areas other than nasolabial folds and lips (Restylane and |

|Restylane-L only) has not been established in controlled clinical studies. |

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|The Restylane family of products is available only through a licensed practitioner. |

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|Dysport |

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|IMPORTANT SAFETY INFORMATION |

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|Indication: Dysport for Injection (abobotulinumtoxinA) is a prescription injection for temporary improvement in the look of moderate to severe frown lines between the eyebrows |

|(glabellar lines) in adults less than 65 years of age. |

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|Warnings/Precautions: |

|Distant Spread of Toxin Effect: The effects of Dysport and all botulinum toxin products may spread from the area of injection to produce symptoms consistent with botulinum toxin |

|effects. Symptoms of botulism can happen hours, days, or weeks after injection. Symptoms may include swallowing or breathing problems, generalized muscle weakness, double or blurred|

|vision, drooping eyelids, hoarseness, voice changes, trouble speaking clearly, or loss of bladder control. Swallowing and breathing difficulties can be life threatening and there |

|have been reports of death. The risk of symptoms is probably greatest in children treated for spasticity but symptoms can also occur in adults, particularly in those patients who |

|have underlying conditions that would predispose them to these symptoms. |

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|The toxic effects have been reported at doses similar to those used to treat muscle spasms in the neck. Lower doses, in both approved and unapproved uses, have also caused toxic |

|effects. This includes treatment of children and adults for muscle spasms. |

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|The potency Units of Dysport are not interchangeable with other preparations of botulinum toxin products and, therefore, units of biological activity of Dysport cannot be compared |

|to or converted into units of any other botulinum toxin products. |

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|Recommended dose and frequency of administration should not be exceeded. Immediate medical attention may be required in cases of respiratory, speech or swallowing difficulties. |

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|Dysport may not be right for you if: you have surgical changes to your face, very weak muscles in the treatment area, your face looks very different from side to side, the injection|

|site is inflamed, you have droopy eyelids or sagging eyelid folds, deep facial scars, thick oily skin, or if your wrinkles can't be smoothed by spreading them apart. |

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|Adverse Events: The most common side effects (≥ 2%) are nose and throat irritation, headache, injection site pain, injection site skin reaction, upper respiratory tract infection, |

|eyelid swelling, eyelid drooping, sinus inflammation and nausea. |

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|Ask your doctor if Dysport is right for you. |

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|You are encouraged to report negative side effects of prescription drugs to the FDA. Visit medwatch or call 1-800-FDA-1088. |

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