Breast Cancer
Breast Cancer
Title: CALGB 40502: A Randomized Phase III Trial of Weekly Paclitaxel Compared to Weekly Nanoparticle Albumin Bound
Nab-Paclitaxel or Ixabepilone Combined with Bevacizumab as First-Line Therapy for Locally Recurrent or Metastatic Breast
Cancer.
Purpose: To compare the anticancer effects and side effects of these three different chemotherapy drugs given on a weekly schedule in
combination with bevacizumab.
Eligibility Subjects must be 18 years or older with invasive breast cancer; Stage IV or Stage IIB, not agreeable to local therapy.
Principal Investigator: Truica, Cristina
Phase: III
For more information, contact: Hagy, Melissa
Telephone Number: 410-601-9083
Email mhagy@
Approved Enrollment Number: 10
Current Enrollment: 0
Breast Cancer
Title: SWOG S0622, Phase II Studies of Two Different Schedules of Dasatinib (NSC-732517) in Bone-Metastasis Predominant
Metastatic Breast Cancer.
Purpose: This study is investigational and is being done to find out if taking the drug dasatinib by mouth by either of two different
dosing schedules will help control cancer and whether it will affect the bones.
Eligibility Patients who have stage IV breast cancer which is bone-predominant. Patients may have 0 to 1 prior chemotherapy regimens
for metastatic disease. Patients who are ER and/or PgR+ must have progressed on at least one hormonal therapy in metastatic
setting. Measurable or non-measurable disease. Zubrod performance status 0-2. Only adults older than 18 can participate.
EKG with OTc ................
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