Health Services Research
But hot off the presses, we have Erin Krebs’ SPACE trial, which is the very first yearlong pragmatic randomized trial of opioids versus nonopioids for chronic back, hip, or knee pain, published two weeks ago in JAMA, showing that nonopioid medications were equivalent to opioids for pain-related functional interference, superior to opioids in terms of pain severity with fewer side effects. ................
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