Department of Veterans Affairs Outpatient Pharmacy ...
Lomitapide is metabolized primarily by CYP 3A4 and therefore is vulnerable to interactions involving drugs that inhibit or induce metabolism of CYP 3A4. Lomitapide is an inhibitor of P-glycoprotein (P-gp) and therefore concomitant administration of lomitapide may increase exposure of the P-gp substrate drug. ... and cetirizine four days prior ... ................
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