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Drug Interactions. Drug-Drug Interactions. Dexlansoprazole DDR is metabolized by CYP2C19 and CYP3A4 and has the potential for drug interactions mediated by these enyzmes. Dexlansoprazole DDR may increase serum levels of tacrolimus by inhibition of CYP3A4. Clopidogrel is a pro-drug that is converted to its active metabolite by two main metabolic ... ................
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