Paper One: MACVSc
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Australian College of Veterinary Scientists
Fellowship Examination
June/July 2009
Veterinary Clinical Pathology (Principles)
Paper 1
Perusal time: twenty (20) minutes
Time allowed: three (3) hours after perusal
Answer five (5) from the seven questions only
All questions are of equal value
Subsections of questions are of equal value unless stated otherwise
Commence each question on a new page
Paper 1: Veterinary clinical pathology
Answer five (5) from the seven questions only.
1. Write notes on four (4) of following:
a) cell counting and sizing technologies in automatic haematology analysers
b) osmometry
c) heterogeneous enzyme immunoassays (ELISA)
d) the use of polymerase chain reaction (PCR) technology in the commercial laboratory
e) immunocytological techniques.
2. You are asked to establish an exciting new biochemical test that has implications for detecting early renal disease in dogs and cats. Outline your approach to establishing this test within your laboratory. Include in your answer quality assurance issues and the process of establishing a reference interval.
3. Discuss the factors that affect the measurement of serum enzymes. Give examples of each factor using a species and enzyme of your choice.
4. Discuss the use of serum protein electrophoresis (SPE) in disease investigation. Include specific examples in your answer.
5. Describe the classification and pathogenesis of, and laboratory findings for, haemolytic anaemia. Include in your answer examples of type and causation in dogs, cats, horses and cattle.
6. Describe the mechanisms or kinetics and laboratory findings associated with each of the following. In your answer, include any significant species differences or characteristics, with reference to the dog, cat, horse or ruminant, where applicable.
a) physiologic neutrophilia
b) corticosteroid-induced neutrophilia
c) inflammatory demand neutrophilia.
7. Discuss the pathophysiology of proteinuria. Include in your answer the types of laboratory tests that can be used to investigate proteinuria in animals, any species limitations for the tests, and how other tests may help to localise the particular causes of proteinuria.
End of paper
[pic]
Australian College of Veterinary Scientists
Fellowship Examination
June/July 2009
Veterinary Clinical Pathology (Applied)
Paper 2
Perusal time: twenty (20) minutes
Time allowed: three (3) hours after perusal
Answer both part A and part B
All questions are of equal value
Subsections of questions are of equal value unless stated otherwise
Paper 2: Veterinary clinical pathology
Part A
Cases with clinical pathology data for interpretation
All questions are of equal value.
Answer two (2) out of the three cases with associated clinical pathology data below.
CASE 1:
A 24-month-old Friesian bull was presented recumbent with sunken eyes, anorexia and lethargy of two-three days duration. Physical examination revealed a distended abdomen, normal temperature, absence of ruminal contractions and lack of faeces upon rectal palpation. No other abnormalities were detected upon rectal palpation.
Comment on the blood results and provide a report for the clinician that includes your interpretation and conclusions. Discuss the implications of these results with regard to how they may impact on the management of the patient. Outline any further laboratory investigation that could be undertaken to assist with the diagnosis and justify your suggestions.
| | | | |% |x 109/L | |
|Hb |123 g/L |(80-150) |WBC | |20.1 |(4.0-12.0) |
|RBC |7.44 x 1012/L |(5.00-10.00) |Neut |76 |15.3 |(0.6-4.0) |
|HCT |0.33 |(0.24-0.45) |Lymp |19 |3.8 |(2.5-7.5) |
|MCV |44 fL |(40-60) |Mono |3 |0.6 |(0.0-0.8) |
|MCH |17 pg |(11-17) |Eos |1 |0.2 |( ................
................
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