UKMi Q&A xx - SPS
Therefore for every 5mg of oral prednisolone, 20mg of IV hydrocortisone, can be given. The biological half-life of prednisolone is 12 to 36 hours (5,7), which allows once-daily dosing. Hydrocortisone has a shorter biological half-life ranging from 8 to 12 hours (5,7). ................
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