Compatibility of Commonly Used Intravenous Drugs
PRINTER-FRIENDLY VERSION AT
Compatibility of
ll
A
s
ite
d.
ib
te
oh
no
pr
e
is
is
rw
on
si
he
is
ot
m
er
ss
le
tp
un ou
up
ith
ro
w
G
rt
ng
pa
hi
in
is
bl
or
Pu
le
ho
on
ah in w
cM
n
M
tio
11
uc
20
od
?
pr
ht
Re
rig ed.
py
rv
se
re
ht
Co
rig
Commonly Used
Intravenous
Drugs
LISA CAYO, PHARMD
Clinical Pharmacy Coordinator
Garden City Hospital
Garden City, Michigan
T
he number of available IV
medications continues to expand.
Many institutions have observed an
increase in patient acuity and a rise in the
number of medications administered to
each patient. This increases the likelihood
that multiple IV medications will need
to be administered concurrently.
medication is combined or added to an IV fluid. It is
important to recognize that compatibility is not just
a function of the drugs themselves, but also can be
dependent on a variety of factors including the concentration, temperature, storage vehicle, infusion solution,
order of mixing, and administration technique. Compatibility differences even have been reported for different
brands of the same drug.
Three types of incompatibilities are commonly discussed: physical, chemical, and therapeutic. Physical
d.
These factors contribute to the escalating complexity of IV drug administration and have resulted in an
ever-increasing number of possible incompatibilities.
The potential for serious and life-threatening adverse
drug events exists when incompatible medications are
infused together. Therefore, it is important to verify drug
compatibility prior to coadministration. A clear and concise compatibility chart can be a useful tool in helping to
deliver safe, high-quality IV therapy to patients.
A chance of incompatibility exists whenever any
Text continues on page 6
I N D E P E N D E N T LY D E V E L O P E D B Y M C M A H O N P U B L I S H I N G
P H A R M AC Y P R AC T I C E N E WS ? S E P T E M B E R 2 0 1 1
1
I
C
C
C
N
C
I
C
C
C
C
C
C
I
C
I
C
C
I
N
N
I
I
C
C
C
I
I
I
N
C
C
C
C
N
C
C
C
C
C
C
H
C
C
C
C
C
C
C
C
C
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
N
C
N
N
N
N
C
I
C
C
C
C
C
N
N
N
C
N
C
C
C
C
N
C
N
C
ll
rig
N
C
I
C
C
C
C
N
C
N
I
N
N
N
N
C
I
N
C
N
C
I
N
N
N
N
N
N
I
N
N
S
C
N
I
I
N
I
I
I
N
I
N
N
C
N
N
N
N
I
S
I
C
N
N
N
C
N
N
I
N
C
I
I
N
N
N
N
I
N
C
N
A
I
N
N
I
N
N
I
N
N
C
N
N
N
N
N
N
N
C
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
N
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
N
N
C
N
N
N
N
N
N
N
N
N
N
N
N
N
C
N
C
N
C
C
C
C
N
N
N
N
C
N
N
N
C
N
C
N
I
C
N
N
N
N
N
I
N
C
I
N
I
I
I
C
N
C
N
N
C
N
N
C
N
N
N
C
N
N
I
I
N
I
I
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
C
I
C
N
C
C
N
C
C
C
C
C
N
C
C
C
C
C
C
C
I
C
C
C
C
N
C
C
C
C
C
C
C
C
I
C
C
N
C
N
C
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
I
C
C
N
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
C
C
I
A
C
C
I
C
I
C
C
N
C
C
C
C
C
C
C
N
C
C
N
C
C
I
I
I
I
I
I
C
I
C
I
C
I
N
I
C
C
C
C
C
C
I
C
N
C
N
C
C
C
I
C
N
I
C
N
C
C
C
N
C
C
C
C
I
C
I
I
I
N
I
C
C
C
C
N
N
C
C
C
N
N
N
N
N
N
N
I
C
C
C
C
I
I
I
N
N
N
N
I
N
C
N
N
I
N
C
C
N
C
N
I
I
C
N
C
C
C
C
I
C
I
N
C
N
C
C
C
C
C
N
C
C
N
C
N
N
C
I
C
N
C
C
C
C
I
C
I
I
C
N
I
C
C
C
C
N
N
C
C
C
C
N
N
N
C
C
N
C
C
I
C
C
N
C
C
N
C
N
N
N
C
C
C
C
C
C
C
C
C
C
C
C
C
I
C
I
N
C
N
I
C
C
C
C
N
C
C
N
C
N
C
N
C
C
C
C
I
C
C
N
C
N
I
C
C
C
C
N
N
C
C
C
C
N
I
C
C
C
I
C
I
I
C
N
C
C
C
C
C
N
N
C
N
C
N
I
C
I
C
N
C
C
C
C
C
N
N
N
C
N
N
N
N
C
I
C
C
C
C
I
C
C
N
C
N
C
C
C
C
C
N
C
C
N
C
C
C
I
C
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
I
C
I
I
C
C
I
C
C
C
I
N
C
C
C
C
I
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
I
I
N
I
I
I
I
I
I
I
N
I
N
I
I
I
ite
d.
ib
te
oh
no
pr
e
is
is
rw
on
si
he
is
ot
m
er
ss
le
tp
un ou
up
ith
ro
w
G
rt
ng
pa
hi
in
is
bl
or
Pu
le
ho
on
ah in w
cM
n
M
tio
11
uc
20
od
?
pr
ht
Re
rig ed.
py
rv
se
re
ht
N
C
N
I
N
Anidulafungin
C
C
C
C
C
C
N
I
N
N
C
N
I
N
N
N
C
N
I
C
N
N
N
C
N
I
C
C
I
C
C
C
C
C
C
C
C
C
N
N
C
N
N
C
C
C
C
C
N
N
C
N
N
C
C
C
N
C
C
I
I
C
N
N
C
I
C
C
C
C
N
N
N
C
N
N
C
C
C
C
I
I
H
N
N
C
C
N
N
C
C
C
C
I
N
C
C
N
N
I
C
N
I
C
C
C
C
I
I
N
C
C
N
N
I
C
N
N
C
C
C
C
I
C
N
C
C
C
C
N
N
N
N
C
N
N
C
C
I
N
N
N
N
C
C
I
N
N
C
N
I
C
C
C
C
I
C
N
I
C
N
C
C
C
I
N
C
N
N
C
C
C
C
C
C
N
I
I
N
C
C
C
C
N
N
C
N
I
C
C
C
I
I
C
N
C
C
N
C
C
I
C
C
N
I
C
N
I
C
C
N
A
C
N
I
N
N
C
C
N
N
C
C
C
S
N
C
N
I
C
C
C
C
I
C
C
C
C
C
C
C
I
I
I
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
N
N
N
C
N
N
C
C
C
I
I
C
C
C
C
C
C
C
C
I
C
C
C
C
N
I
A
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
I
C
I
I
N
I
I
I
N
N
I
I
I
I
I
I
I
I
I
I
I
I
I
N
I
C
I
N
C
C
N
N
C
C
N
C
C
C
C
C
C
I
C
C
C
C
C
C
C
C
C
C
C
I
N
C
N
I
N
C
C
C
N
C
C
C
C
I
I
I
I
C
I
C
I
C
C
C
I
C
I
C
I
C
C
I
I
C
C
N
C
N
N
N
C
I
N
N
I
N
N
N
I
C
N
C
I
C
N
C
C
I
C
C
I
N
C
C
N
C
C
C
C
C
I
N
C
C
C
C
C
C
C
C
C
C
C
I
C
C
C
C
C
C
N
N
C
N
C
N
N
C
C
C
N
N
N
N
C
N
N
N
C
N
C
C
C
I
C
C
C
C
C
C
C
I
I
C
N
N
C
C
C
C
C
I
N
C
I
N
I
I
C
N
C
C
I
C
I
C
C
C
C
N
C
C
N
N
N
C
N
N
C
C
C
C
I
C
I
C
C
C
C
C
C
N
C
C
C
C
I
C
C
C
C
C
C
I
C
C
N
N
C
N
N
C
C
C
C
C
C
N
C
C
N
C
C
C
N
C
C
C
C
I
C
C
C
C
N
C
C
I
C
N
C
C
C
C
C
C
C
C
C
N
C
C
C
C
N
C
C
C
C
C
C
C
C
I
C
C
C
N
N
C
C
C
I
C
C
N
N
C
N
N
C
C
C
C
C
C
N
C
C
N
C
C
C
N
C
C
I
C
I
C
C
C
C
C
C
C
C
C
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
C
N
N
N
N
N
N
N
C
N
N
N
N
N
C
N
N
N
N
N
C
C
C
N
N
C
N
I
C
C
C
C
C
N
I
C
N
C
C
N
N
N
C
C
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
N
N
C
C
I
C
C
C
C
C
C
N
C
C
C
C
C
C
N
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
N
s
Bumetanide
Calcium gluconate
Caspofungin
Cefazolin
Cefepime
Cefotaxime
Cefoxitin
Ceftaroline
Ceftazidime
Ceftizoxime
Ceftriaxone
Ciprofloxacin
Clindamycin
Daptomycin
Dexamethasone
D5W
Diazepam
Diltiazem
Diphenhydramine
Dobutamine
Dopamine
Doripenem
Doxycycline
Enalaprilat
Epinephrine
Eptifibatide
Esmolol
Esomeprazole
Famotidine
Fentanyl
N
N
C
C
C
C
C
C
C
C
C
N
C
C
C
I
C
C
C
C
C
C
C
C
C
N
C
C
C
I
C
C
C
C
C
C
C
C
N
C
C
C
I
C
C
C
C
C
N
C
N
C
C
C
N
C
N
C
N
N
C
C
C
C
C
C
C
C
C
C
C
N
C
C
C
I
C
C
C
C
N
C
C
C
C
C
C
C
N
C
C
C
C
C
C
N
C
C
C
I
C
N
C
C
C
I
C
N
N
N
N
N
C
C
N
C
C
C
C
Protect from light. b Testing was performed with ethylenediaminetetra-acetic acid (EDTA)-free formulation.
d.
KEY
A = Physically compatible for at least 2 hours
H = Physically compatible for at least 1 hour
C = Physically compatible
I = Incompatible
D = Physically compatible in dextrose 5% in water
N = Information on compatibility is not available or not adequate
E = Physically compatible for at least 5 minutes
R = Physically compatible for 24 hours under refrigeration
G = Physically compatible in glass bottle only
S = Physically compatible in 0.9% sodium chloride
2
Gentamicin
N
I
I
Bivalirudin
Furosemide
C
N
Ampicillin-sulbactam
Aztreonam
Fluconazole
C
C
N
Azithromycin
Fentanyl
I
N
N
Argatroban
Famotidine
Esomeprazole
Esmolol
Eptifibatide
Epinephrine
Enalaprilat
Doxycycline
Doripenem
Dopamine
Dobutamine
Diphenhydramine
Diltiazem
Diazepam
Dextrose 5% in water
Dexamethasone
Daptomycin
Clindamycin
Ciprofloxacin
Ceftriaxone
Ceftizoxime
Ceftazidime
Ceftaroline
Cefoxitin
Cefotaxime
Cefepime
Cefazolin
Caspofungin
Calcium gluconate
Bumetanide
Bivalirudin
Aztreonam
Azithromycin
Argatroban
Anidulafungin
Ampicillin-sulbactam
Ampicillin
C
N
C
Ampicillin
a
Amiodarone
N
C
C
Amiodarone
(continued)
Co
A
C
Acyclovir
Amikacin
Amikacin
Acyclovir
Table. Compatibility of Selected IV Drugs
I N D E P E N D E N T LY D E V E L O P E D B Y M C M A H O N P U B L I S H I N G
C
Labetalol
Levofloxacin
Linezolid
Lorazepam
Magnesium sulfate
Mannitol
Meropenem
Methylprednisolone sod. Succ.
Metoclopramide
Metronidazole
Micafungin
Midazolam
Morphine sulfate
Nafcillin
Nitroglycerin
Nitroprussidea
Norepinephrine
Ondansetron
Palonosetron
Pantoprazoleb
Penicillin G Potassium
Phenylephrine
Phenytoin
Piperacillin-tazobactam
Potassium chloride
Prochlorperazine
Propofol
Ringer¡¯s, lactated
Sodium bicarbonate
Sodium chloride 0.9%
Tacrolimus
Tigecycline
Tobramycin
TMP-SMX
Vancomycin
Vasopressin
Voriconazole
C
N
C
N
C
N
I
N
C
C
I
N
I
I
N
C
I
I
I
C
I
C
N
C
C
I
C
C
C
C
C
C
Acyclovir
C
C
N
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
I
C
C
C
I
C
C
C
C
C
C
I
C
C
C
Amikacin
C
I
C
C
N
C
N
C
I
C
C
N
C
N
C
N
C
N
C
C
N
I
C
N
N
N
I
N
C
I
C
N
C
C
C
Amiodarone
C
C
C
C
C
I
N
N
I
C
C
S
N
N
N
N
N
C
N
N
C
N
N
N
C
C
C
C
C
C
C
C
C
C
N
N
C
C
N
N
N
N
N
N
N
N
N
I
N
N
N
N
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
N
C
N
C
C
C
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
N
I
C
C
C
C
C
C
H
N
C
C
C
C
C
C
C
C
I
N
C
C
C
C
C
C
I
I
I
C
C
C
C
C
N
C
I
C
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
I
C
I
C
N
C
I
I
C
N
N
N
N
C
C
C
C
C
C
C
N
C
C
C
C
C
C
I
C
C
C
C
C
C
C
N
C
C
I
C
C
C
N
C
C
N
C
C
C
C
I
I
I
N
I
I
I
I
I
C
N
N
C
C
N
C
C
C
C
N
N
C
C
I
C
C
C
C
N
I
C
N
N
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
N
C
C
C
C
C
I
I
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
C
N
C
C
C
C
N
N
C
C
C
C
C
C
N
N
N
N
N
N
N
N
N
C
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
C
Insulin, regular
C
I
Imipenem-cilastatin
Hydromorphone
C
C
Hydrocortisone Sod. Succ.
C
C
Heparin
C
C
Granisetron
I
C
C
C
A
C
C
ll
rig
N
C
I
N
N
N
N
N
N
C
N
I
N
I
N
I
N
I
C
C
I
N
I
N
N
I
C
I
I
C
N
C
N
I
N
N
C
Ampicillin
I
N
N
N
I
N
C
N
I
N
N
N
N
N
I
C
C
N
N
I
N
N
I
N
R
N
C
N
C
N
I
N
N
C
Ampicillin-sulbactam
C
I
C
C
C
C
C
N
C
C
C
C
C
C
C
C
C
N
C
I
C
C
C
N
N
I
C
C
N
C
C
C
C
C
Anidulafungin
C
N
N
N
N
N
N
N
C
C
N
C
C
C
C
N
N
N
C
N
N
N
N
N
C
N
C
N
C
N
N
N
C
N
Argatroban
N
N
N
N
N
N
N
N
N
I
N
N
N
N
C
C
C
N
N
N
I
I
N
N
C
N
C
N
C
I
N
N
C
C
Azithromycin
I
C
C
N
C
C
I
N
C
C
N
C
C
C
C
C
I
C
C
I
C
C
I
C
C
C
C
C
C
C
N
N
C
C
Aztreonam
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
C
N
N
C
I
C
C
I
N
N
C
C
C
C
C
C
I
C
C
Bivalirudin
C
C
C
N
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
I
C
C
N
C
C
C
C
C
C
C
I
C
C
C
Bumetanide
C
N
C
N
I
C
C
C
C
C
C
C
C
C
C
C
C
C
C
I
C
C
N
C
C
I
C
C
C
C
I
C
C
C
Calcium gluconate
N
C
C
C
I
C
N
N
C
C
I
C
I
C
C
C
N
N
C
I
I
C
C
N
N
I
C
C
C
C
I
C
C
C
Caspofungin
C
N
C
N
C
C
C
N
C
C
C
C
C
C
C
C
N
C
C
I
N
C
I
C
C
C
C
C
C
N
I
N
C
C
Cefazolin
C
I
I
N
C
I
C
N
I
N
N
N
N
N
I
C
I
N
N
I
C
C
I
N
N
C
C
I
C
N
C
N
C
I
Cefepime
C
C
C
N
I
C
C
N
C
C
C
C
C
C
C
C
I
C
C
I
N
C
I
C
C
I
C
C
C
C
I
N
C
C
Cefotaxime
C
C
C
N
I
C
C
N
C
C
C
C
C
C
C
C
C
C
C
I
N
C
I
C
C
I
C
C
C
C
I
N
C
C
Cefoxitin
C
N
C
N
C
C
C
N
C
C
N
N
N
C
C
N
C
N
N
N
N
C
N
C
C
C
C
N
N
C
C
N
C
C
Ceftaroline
C
C
C
N
C
C
C
N
I
C
C
C
I
C
N
C
N
C
C
I
N
C
I
N
C
C
C
C
C
C
I
N
C
C
Ceftazidime
C
C
C
N
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
I
N
C
I
C
C
C
C
C
C
C
I
N
C
C
Ceftizoxime
C
I
C
N
C
C
C
N
C
C
C
C
C
C
N
C
C
C
C
I
N
C
I
C
I
C
C
C
C
I
I
N
C
C
Ceftriaxone
C
I
N
N
I
C
C
N
C
N
N
N
N
C
C
C
I
N
N
I
I
C
N
I
C
I
C
C
C
C
N
N
C
C
Ciprofloxacin
C
C
C
N
C
C
C
N
N
C
C
C
C
C
C
C
N
C
C
I
C
C
I
C
C
C
C
C
C
N
I
C
C
C
Clindamycin
C
C
C
C
C
C
I
N
C
C
C
I
C
C
C
C
I
N
C
I
C
C
C
N
C
C
C
C
C
C
C
I
C
C
Daptomycin
C
I
C
C
C
C
C
N
I
C
C
C
C
C
C
C
I
C
C
I
C
C
I
C
C
C
C
C
C
I
I
N
C
C
Dexamethasone
N
C
N
I
N
C
N
C
C
C
C
G
C
C
C
C
C
C
C
I
C
C
N
C
C
C
C
N
C
C
N
C
N
C
D5W
N
I
I
I
I
I
I
N
I
N
N
I
I
I
N
I
I
I
I
I
C
I
I
I
I
I
N
I
I
I
I
I
I
I
Diazepam
C
C
C
C
N
C
C
I
C
C
N
C
C
C
C
C
I
C
C
I
I
C
C
N
N
N
C
C
C
C
C
C
C
C
Diltiazem
C
C
C
C
I
C
C
N
C
C
N
C
I
C
C
C
I
C
C
I
C
C
C
C
C
I
C
C
C
C
I
C
C
C
Diphenhydramine
C
N
C
C
C
C
C
I
N
C
C
C
N
C
C
C
I
I
C
I
I
C
C
C
C
I
C
C
C
C
I
C
C
C
Dobutamine
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
N
C
C
I
C
C
C
C
C
N
C
C
C
C
I
C
C
C
Dopamine
C
C
C
N
C
C
C
C
C
C
N
N
N
C
C
N
C
N
C
N
N
C
N
I
N
C
C
C
C
C
N
C
N
C
Doripenem
C
C
C
N
I
C
C
N
C
C
I
C
C
C
C
I
C
I
C
I
I
C
C
C
N
I
C
C
N
C
I
C
C
C
Doxycycline
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
C
N
C
C
I
C
C
C
C
N
C
C
C
C
C
N
C
C
C
Enalaprilat
C
C
C
N
C
C
C
I
C
C
C
C
C
C
C
C
C
C
C
I
C
C
C
C
C
I
C
C
C
C
I
C
C
C
Epinephrine
C
C
C
C
C
C
C
C
C
C
N
C
N
C
C
C
N
N
C
I
C
C
C
N
N
C
C
N
C
C
C
C
N
N
Eptifibatide
C
C
C
N
N
C
C
C
C
C
N
C
C
C
C
C
I
C
C
N
C
C
C
C
C
C
C
C
C
C
N
C
C
C
Esmolol
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
N
C
N
C
I
N
N
N
N
N
N
Esomeprazole
C
C
C
N
C
C
C
N
C
C
C
C
C
C
C
C
I
C
C
N
I
C
C
C
C
C
C
C
C
C
I
C
C
C
Famotidine
C
C
C
N
C
C
C
N
C
C
C
C
C
C
C
C
I
C
C
I
C
C
C
C
N
C
C
C
C
C
I
C
C
C
Fentanyl
s
C
N
ite
d.
ib
te
oh
no
pr
e
is
is
rw
on
si
he
is
ot
m
er
ss
le
tp
un ou
up
ith
ro
w
G
rt
ng
pa
hi
in
is
bl
or
Pu
le
ho
on
ah in w
cM
n
M
tio
11
uc
20
od
?
pr
ht
Re
rig ed.
py
rv
se
re
ht
C
Co
I
N
Table continues on page 4
d.
I N D E P E N D E N T LY D E V E L O P E D B Y M C M A H O N P U B L I S H I N G
3
Bivalirudin
Bumetanide
Calcium gluconate
Caspofungin
Cefazolin
Cefepime
Cefotaxime
Cefoxitin
Ceftaroline
Ceftazidime
Ceftizoxime
Ceftriaxone
Ciprofloxacin
Clindamycin
Daptomycin
Dexamethasone
Dextrose 5% in water
Diazepam
Diltiazem
Diphenhydramine
Dobutamine
Dopamine
Doripenem
Doxycycline
Enalaprilat
C
C
N
C
C
C
N
C
C
N
C
N
C
N
C
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
I
C
C
C
C
C
C
C
C
I
C
C
C
C
I
I
I
I
N
C
I
C
C
I
I
N
N
C
N
Gentamicin
Co
I
N
C
N
I
C
C
C
C
C
N
N
N
C
C
N
C
N
C
C
C
I
C
I
C
C
C
C
C
C
C
C
C
C
ll
rig
N
s
Heparin
Hydrocortisone
Hydromorphone
Imipenem-cilastatin
Insulin, regular
Labetalol
Levofloxacin
Linezolid
Lorazepam
Magnesium sulfate
Mannitol
Meropenem
Methylprednisolone
Metoclopramide
Metronidazole
Micafungin
Midazolam
Morphine sulfate
Nafcillin
Nitroglycerin
Nitroprussidea
Norepinephrine
Ondansetron
Palonosetron
Pantoprazoleb
Penicillin G
Phenylephrine
Phenytoin
C
C
C
N
Esmolol
N
C
C
C
N
C
C
C
C
C
N
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
I
I
S
N
C
N
N
C
C
C
C
I
C
C
C
C
C
C
C
C
I
C
C
C
N
I
N
N
N
C
C
I
C
C
C
N
N
C
C
C
C
I
C
C
N
N
N
C
C
N
C
C
C
N
C
C
C
C
C
C
C
C
C
I
C
C
C
C
I
N
N
I
C
C
I
C
C
C
N
N
C
C
C
C
N
C
C
N
N
C
C
C
N
C
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
N
C
N
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
I
N
N
C
N
I
N
C
C
N
C
C
C
C
C
N
C
C
I
N
C
I
C
N
I
C
C
N
C
N
C
C
C
C
C
N
C
C
N
C
C
C
N
C
N
N
C
N
N
C
C
C
C
C
C
H
C
I
C
C
C
C
N
C
C
C
C
I
N
I
N
N
C
C
C
N
N
C
N
N
C
C
C
N
I
C
C
N
N
C
N
N
C
C
C
C
C
N
N
I
I
I
C
C
I
N
N
C
I
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
N
C
I
C
I
C
C
C
N
N
C
C
C
C
C
I
C
N
I
C
C
C
C
N
C
C
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
I
C
C
C
C
C
C
C
N
N
C
C
C
C
C
C
C
C
C
N
C
C
N
C
C
C
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
C
I
I
C
C
N
I
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
C
N
N
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
N
N
N
I
N
N
C
C
C
N
C
N
I
C
C
N
C
C
I
I
C
C
I
C
I
C
C
N
C
C
C
C
C
C
C
N
C
C
C
N
C
C
C
N
N
N
C
N
N
C
C
C
C
C
C
I
C
C
C
C
C
C
N
C
C
C
N
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
N
N
N
N
N
C
N
N
N
C
N
N
C
N
N
N
N
N
N
N
N
N
N
C
C
I
I
C
C
C
C
N
N
C
N
C
N
N
N
N
C
C
C
C
C
C
N
I
C
N
N
C
C
C
I
I
C
C
I
I
C
C
C
C
I
C
C
C
N
I
N
I
C
C
C
I
C
C
C
N
N
C
C
C
C
C
N
C
N
N
N
C
N
N
C
C
C
C
C
C
I
C
C
C
C
C
C
C
C
C
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
N
C
C
C
C
C
C
C
N
N
I
C
C
C
N
C
C
C
C
C
C
C
C
C
C
I
C
N
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
N
N
I
N
N
N
N
N
N
N
C
C
N
N
N
N
N
N
N
N
N
N
N
N
N
C
N
I
N
I
C
C
N
N
I
C
C
N
N
N
N
C
N
I
C
C
I
I
C
C
N
C
C
N
C
C
C
I
C
C
C
I
C
C
C
N
C
I
C
I
C
C
N
C
C
C
C
C
C
C
N
C
C
C
I
C
N
C
C
N
N
C
C
I
C
C
C
C
C
C
N
C
C
C
C
C
C
N
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
N
C
C
C
N
C
C
C
N
I
N
C
N
N
N
C
C
C
I
C
N
C
C
N
C
C
C
N
C
C
C
C
N
N
N
C
C
N
I
C
C
N
N
N
C
C
C
C
N
C
C
C
N
N
C
C
N
C
C
C
C
C
C
N
C
C
N
C
C
C
N
C
I
C
G
I
C
C
C
C
N
C
C
C
C
C
N
C
C
C
N
C
I
C
N
I
N
C
C
N
C
C
C
C
I
C
N
C
C
N
I
C
C
N
C
C
C
C
I
C
I
N
C
N
C
C
C
N
C
N
C
C
C
C
C
N
C
C
N
N
C
C
N
C
C
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
N
C
I
C
N
I
I
C
C
C
C
C
C
C
C
C
I
C
C
C
N
C
N
C
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
N
C
C
C
I
C
I
C
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
C
I
C
C
C
C
N
I
C
C
C
C
N
C
C
C
C
C
N
C
N
C
C
C
N
C
I
N
C
C
N
N
I
I
C
C
N
C
C
I
N
I
I
C
I
I
I
I
N
C
C
N
C
N
I
N
I
I
I
N
C
C
C
C
I
N
N
N
N
C
N
C
C
N
C
N
C
C
N
C
C
C
N
C
N
C
C
I
C
C
I
C
N
I
C
C
N
C
N
C
C
C
C
C
I
C
C
N
N
C
C
N
C
C
C
C
C
C
N
C
C
N
C
C
C
N
C
C
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
I
C
I
I
N
I
I
I
N
N
I
I
I
I
I
I
I
I
I
N
I
I
I
I
I
I
I
I
I
I
I
I
I
N
I
I
I
I
N
N
N
I
N
I
I
ite
d.
ib
te
oh
no
pr
e
is
is
rw
on
si
he
is
ot
m
er
ss
le
tp
un ou
up
ith
ro
w
G
rt
ng
pa
hi
in
is
bl
or
Pu
le
ho
on
ah in w
cM
n
M
tio
11
uc
20
od
?
pr
ht
Re
rig ed.
py
rv
se
re
ht
Granisetron
N
Gentamicin
Aztreonam
C
I
Furosemide
Azithromycin
N
C
Fluconazole
Argatroban
N
C
Fentanyl
Anidulafungin
C
N
Famotidine
Ampicillin-sulbactam
N
S
Esomeprazole
Ampicillin
I
N
Eptifibatide
Amiodarone
C
C
Epinephrine
Amikacin
C
C
A
C
Furosemide
Fluconazole
N
C
I
N
N
C
N
I
C
C
C
C
I
N
C
N
N
N
N
N
N
I
C
C
C
C
C
I
C
I
C
N
I
C
C
C
C
N
I
C
C
C
N
C
C
C
N
N
C
N
I
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
I
C
N
I
I
C
N
N
I
I
N
N
C
I
I
I
I
N
I
I
I
N
I
C
I
N
I
C
C
C
C
N
C
C
C
C
C
N
C
C
C
I
C
C
I
N
C
N
N
N
N
C
N
C
C
N
C
N
C
C
C
N
C
C
I
C
N
C
C
I
N
C
C
C
I
C
C
C
N
C
N
C
C
C
C
I
N
C
N
I
R
N
C
C
C
N
C
C
N
C
N
C
C
C
C
C
I
C
C
C
C
C
I
N
C
C
C
N
N
N
C
N
C
C
C
N
C
C
C
C
C
I
I
N
I
N
N
C
C
C
I
I
C
C
I
I
C
C
C
C
I
C
C
C
C
I
N
I
I
N
C
I
C
I
C
C
N
C
C
C
C
C
Sodium chloride 0.9%
C
C
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
Tacrolimus
I
C
C
N
N
C
N
N
C
C
C
C
C
C
I
C
C
N
C
C
C
C
C
C
C
N
I
C
C
C
C
C
C
C
C
N
C
I
C
C
C
N
C
C
C
I
C
C
N
C
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
C
I
C
C
C
C
C
N
C
C
C
C
N
C
C
C
C
C
Tobramycin
C
C
C
N
N
C
N
I
C
C
C
C
C
N
N
C
C
C
C
C
I
C
N
C
I
C
I
C
C
C
C
C
C
C
C
d.
Piperacillan-tazobactam I
C
C
N
C
C
C
C
C
TMP-SMX
C
I
N
I
I
C
N
N
N
C
I
I
I
I
C
I
I
C
I
I
I
N
I
C
I
N
I
C
I
I
I
N
I
N
I
C
N
N
I
I
I
I
I
Vancomycin
C
C
C
N
N
C
N
N
N
I
C
C
C
N
N
N
N
N
N
N
N
N
C
I
N
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
I
C
Vasopressin
C
C
C
N
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
N
I
C
C
C
C
N
C
C
C
N
C
N
C
C
C
N
C
Voriconazole
C
C
C
C
C
C
N
C
C
C
C
C
C
C
I
C
C
C
C
C
C
C
C
C
C
C
I
C
C
C
C
C
C
C
C
N
C
N
C
C
C
C
C
Potassium chloride
Prochlorperazine
Propofol
Ringer¡¯s, lactated
Sodium bicarbonate
Tigecycline
a
(continued)
Acyclovir
Table. Compatibility of Selected IV Drugs
Protect from light. b Testing was performed with ethylenediaminetetra-acetic acid (EDTA)-free formulation.
4
I N D E P E N D E N T LY D E V E L O P E D B Y M C M A H O N P U B L I S H I N G
Magnesium sulfate
Mannitol
Meropenem
Methylprednisolone sod. Succ.
Metoclopramide
Metronidazole
Micafungin
Midazolam
Morphine sulfate
Nafcillin
Nitroglycerin
Nitroprussidea
Norepinephrine
Ondansetron
Palonosetron
Pantoprazoleb
Penicillin G Potassium
Phenylephrine
Phenytoin
Piperacillin-tazobactam
Potassium chloride
Prochlorperazine
Propofol
Ringer¡¯s, lactated
Sodium bicarbonate
Sodium chloride 0.9%
Tacrolimus
Tigecycline
Tobramycin
TMP-SMX
Vancomycin
Vasopressin
Voriconazole
C
C
C
C
N
C
C
C
C
C
C
C
C
I
C
C
N
C
C
C
C
C
C
C
C
C
C
I
C
C
C
Fluconazole
C
C
C
N
C
C
I
N
C
N
C
N
I
C
N
C
I
I
C
C
I
C
C
C
C
N
C
C
I
I
N
C
Furosemide
C
C
C
C
C
C
C
C
N
C
C
N
C
C
C
C
C
C
C
C
I
N
C
C
I
C
C
C
C
C
C
I
C
C
C
Gentamicin
C
I
N
C
C
N
C
C
C
C
C
C
N
N
C
C
N
I
C
C
C
I
C
C
C
C
C
C
C
C
C
C
C
I
N
C
C
C
A
C
ll
Linezolid
rig
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
N
N
C
N
C
I
C
C
C
C
N
C
C
C
C
C
C
C
C
C
Granisetron
s
C
C
ite
d.
ib
te
oh
no
pr
e
is
is
rw
on
si
he
is
ot
m
er
ss
le
tp
un ou
up
ith
ro
w
G
rt
ng
pa
hi
in
is
bl
or
Pu
le
ho
on
ah in w
cM
n
M
tio
11
uc
20
od
?
pr
ht
Re
rig ed.
py
rv
se
re
ht
C
C
C
Levofloxacin
C
N
Labetalol
C
Insulin, regular
C
C
Imipenem-cilastatin
C
C
Co
C
C
Lorazepam
C
N
Hydromorphone
C
C
Hydrocortisone Sod. Succ.
C
C
Heparin
C
I
Granisetron
C
N
C
C
C
C
C
N
C
C
C
C
N
C
C
C
C
C
C
C
C
C
I
C
C
N
C
N
C
C
C
C
I
E
I
C
C
Heparin
C
N
C
N
N
C
C
N
N
C
N
C
C
C
C
C
N
C
C
I
C
C
N
C
C
C
C
C
C
N
I
N
C
C
Hydrocortisone
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
N
C
C
I
C
C
N
C
C
I
C
C
C
C
C
C
C
N
Hydromorphone
I
C
I
N
C
C
C
N
N
C
C
C
N
C
C
I
C
C
C
I
N
N
I
C
I
I
R
C
C
C
I
C
C
C
Imipenem-cilastatin
C
C
C
C
C
C
C
I
N
N
N
C
C
N
N
C
N
C
I
I
I
C
I
C
G
C
N
C
C
N
I
C
N
C
Insulin, regular
C
C
C
N
C
C
C
I
C
C
N
C
C
C
C
C
I
N
C
I
I
C
C
C
C
N
C
C
C
C
N
C
C
C
Labetalol
N
N
C
N
C
C
C
N
C
C
N
I
I
N
C
C
I
N
C
I
I
C
I
I
N
C
C
C
C
C
C
C
C
C
Levofloxacin
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
C
I
N
C
I
C
C
C
N
C
C
C
C
C
C
N
C
C
C
Linezolid
C
C
C
C
C
C
C
C
C
C
C
C
C
I
C
I
N
C
I
C
C
N
C
N
C
N
C
C
C
C
C
C
C
Lorazepam
C
C
I
C
C
C
C
C
C
C
C
C
C
C
N
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
C
Magnesium sulfate
I
C
C
C
N
C
C
C
C
C
C
C
C
N
C
C
I
C
C
C
C
N
C
N
C
C
C
I
C
C
C
Mannitol
N
C
C
N
N
C
N
N
N
C
N
C
N
N
N
N
N
N
N
N
I
I
R
C
C
N
N
C
C
C
Meropenem
C
C
N
N
C
N
C
C
C
N
N
I
C
C
I
C
N
C
I
N
C
C
C
N
C
I
C
C
C
Methylprednisolone
C
N
C
C
C
C
C
C
C
C
N
C
C
I
C
C
C
I
C
C
C
C
C
C
I
C
C
C
Metoclopramide
N
C
C
C
C
C
C
C
C
I
N
C
I
C
C
C
N
N
C
N
C
C
C
C
C
C
C
Metronidazole
I
I
N
C
C
C
I
N
N
N
C
I
N
C
N
N
C
N
C
C
N
N
N
N
C
N
Micafungin
C
N
C
C
C
C
C
I
C
C
I
I
C
I
N
N
I
C
C
C
C
I
C
C
C
Midazolam
C
C
C
C
C
C
N
C
C
I
C
C
C
N
C
N
C
C
C
C
N
C
C
C
Morphine sulfate
C
C
C
C
I
C
C
C
I
N
C
C
C
C
C
C
C
C
N
I
N
C
C
Nafcillin
C
C
C
C
N
C
C
I
C
C
C
C
G
C
G
C
C
C
I
C
C
C
Nitroglycerin
C
C
C
N
C
C
I
C
C
I
C
C
C
C
C
C
C
I
C
C
I
Nitroprussidea
C
C
N
C
N
C
C
C
C
C
C
C
C
C
C
C
N
I
C
C
I
C
I
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
C
C
I
C
C
N
C
C
C
N
C
C
C
C
C
C
C
C
C
C
I
C
C
C
C
C
C
N
C
N
C
N
N
C
C
N
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
N
C
N
C
N
I
I
N
N
C
C
N
C
N
N
C
C
C
C
N
C
C
C
N
C
C
C
C
C
N
C
C
N
N
N
C
C
C
C
C
C
C
C
I
C
C
C
C
C
N
C
C
I
C
C
C
C
C
C
N
C
N
C
N
C
C
C
C
N
C
C
C
N
C
C
C
I
C
C
C
C
C
C
N
N
C
N
I
I
I
C
C
C
C
C
C
N
N
N
C
C
C
C
C
I
C
C
C
I
I
I
I
I
I
I
I
I
C
C
C
C
N
I
I
I
C
C
C
C
C
N
C
C
C
C
C
N
N
N
I
I
C
I
C
C
C
C
C
C
C
C
I
N
N
N
C
C
I
G
C
N
C
C
C
C
I
I
C
N
C
C
C
C
C
C
R
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
I
N
C
C
N
C
C
C
E
I
C
I
I
N
C
I
N
C
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
I
C
I
C
N
C
C
C
C
C
C
C
C
C
C
C
C
C
N
N
N
N
N
C
C
C
N
N
C
C
I
C
C
C
C
C
C
C
I
C
C
C
C
N
N
C
C
N
N
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
I
C
C
N
N
C
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
N
C
C
I
C
C
C
N
I
N
N
N
I
N
I
N
I
N
C
N
N
N
I
I
C
C
N
C
C
I
C
C
C
C
C
I
C
C
C
C
I
C
C
C
Norepinephrine
N
I
C
C
I
C
C
C
C
C
I
C
C
C
C
I
C
C
C
Ondansetron
I
N
C
I
C
C
C
C
N
C
C
C
C
C
C
C
C
C
Palonosetron
N
C
I
N
C
I
N
C
N
C
N
C
N
N
N
C
I
Pantoprazoleb
C
I
N
C
C
N
C
N
N
C
N
C
I
N
C
N
Penicillin G
I
C
C
C
N
C
C
C
C
C
C
I
C
C
C
Phenylephrine
I
I
I
I
I
I
I
I
I
I
I
I
I
I
Phenytoin
C
I
N
C
C
C
C
C
I
C
N
C
C
Piperacillin-tazobactam
C
C
C
C
C
C
C
C
I
C
C
C
Potassium chloride
C
C
N
N
C
C
C
I
C
C
N
Prochlorperazine
C
C
N
N
N
I
N
N
N
N
Propofol
N
N
N
C
C
N
C
N
N
Ringer¡¯s, lactated
C
C
C
C
I
N
C
C
Sodium bicarbonate
N
N
C
N
C
N
C
Sodium chloride 0.9%
C
C
N
C
C
C
Tacrolimus
C
C
C
C
N
Tigecycline
I
C
C
C
Tobramycin
I
N
C
TMP-SMX
C
C
Vancomycin
C
Vasopressin
N
C
C
N
C
C
N
N
C
C
C
C
C
C
C
N
N
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
I
I
I
N
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
C
C
C
N
C
C
C
N
I
C
N
C
C
C
C
C
N
N
C
I
C
C
C
N
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
I
C
N
C
C
N
C
C
C
N
I
C
C
C
I
C
C
C
I
C
C
I
I
C
C
C
C
N
I
I
N
N
N
N
C
C
C
C
C
C
N
N
N
I
N
C
C
N
C
N
I
N
C
N
C
N
C
C
G
C
C
C
N
C
C
C
I
C
C
C
C
C
C
C
I
C
C
C
N
I
N
C
C
C
I
I
C
N
N
C
I
C
C
N
C
N
N
C
N
R
C
C
N
C
C
C
C
G
C
C
C
C
C
N
C
I
C
C
N
N
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
N
C
C
I
C
C
C
N
N
C
N
C
C
C
C
N
C
C
N
C
C
C
C
C
C
C
C
C
N
C
I
C
C
C
N
C
C
N
C
C
C
C
C
N
C
C
C
N
C
C
N
C
C
C
C
C
N
C
C
I
I
C
C
I
C
C
C
C
C
C
N
C
N
I
N
I
I
C
N
I
N
I
I
I
I
I
C
N
I
I
I
C
I
I
N
N
I
N
N
C
I
C
C
C
C
C
C
C
C
C
C
N
C
C
N
C
C
C
C
C
N
N
C
I
N
C
C
N
C
N
C
C
C
C
I
N
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
I
C
C
C
N
N
C
N
C
C
C
N
C
C
C
C
C
C
C
C
C
C
C
C
N
C
C
C
C
I
C
C
C
I
N
C
I
C
C
N
N
N
C
C
C
N
C
C
C
C
d.
N
C
Voriconazole
I N D E P E N D E N T LY D E V E L O P E D B Y M C M A H O N P U B L I S H I N G
5
................
................
In order to avoid copyright disputes, this page is only a partial summary.
To fulfill the demand for quickly locating and searching documents.
It is intelligent file search solution for home and business.
Related download
- medicines management pharmacy services mmps ltht
- critical care intravenous drug administration guide
- compatibility of commonly used intravenous drugs
- thames valley y site intravenous drugs compatibility chart
- neonatal medication guideline y site iv
- printer friendly version available at
- parenteral nutrition pn and drug compatibility
- iv drug compatibility chart weebly
Related searches
- 500 most commonly used words
- list of commonly used words
- most commonly used languages in the world
- words not commonly used anymore
- the most commonly used words
- 1000 most commonly used english words
- commonly used words list
- commonly used english words list
- most commonly used words in english
- most commonly used words list
- 4000 most commonly used words
- 1000 commonly used words