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Ariel Mucha

Post-doc

Marie Curie Individual Intra-European Fellowship (IEF)

Research Interests

Novel Supramolecular cylinders and their interaction with DNA; probing

effects of cylinder structure and targeting DNA junctions

Education

|• 29.01.2009 | |defence of the Ph.D. thesis with suma cum laude |

|• 2004-2008 | |Ph.D. studies in Bioinorganic and Biomedical Chemistry Research Group, Faculty of Chemistry, University of Wrocław, (Ph.D. thesis: |

| | |Complexes of nickel(II) ions with adenine nucleotide. Influence of the metal ion on the damage of nucleic acids and their structural|

| | |elements) |

| | | |

|• 1999-2004 | |M.Sc. studies (Environmental Chemistry), Faculty of Chemistry, University of Wrocław |

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Professional Experience

|10/2009-03/2010 | |Post-Doctoral Research Fellow (Marie Curie Action Transfer of Knowledge programme on "Lipidomics in Human Development, Health |

| | |and Chronic Diseases (LIPHEALTH)", Institute of Brain Chemistry and Human Nutrition (IBCHN) London Metropolitan University |

|• 2009 | |Assistant Professor (adjunct), Wrocław Research Center EIT+, Wrocław |

|• 08/2007-02/2008 | |Ph.D. Student Research Fellow in the group of Prof. Roland K.O. Sigel, Institute of Inorganic Chemistry, University of Zurich,|

| | |Switzerland. Fellowship from the International Relations Office of the University of Zurich |

Publications

|A. Mucha, B. Knobloch, M. Jeżowska-Bojczuk, H. Kozłowski, R.K.O. Sigel, Comparison of the acid-base properties of ribose and 2'-deoxyribose nucleotides, |

|Chem. Eur. J., 2008, 14, 6663-6671. |

|A. Mucha, B. Knobloch, M. Jeżowska-Bojczuk, H. Kozłowski, R.K.O. Sigel, Effect of the ribose versus 2'-deoxyribose residue on the metal ion-binding |

|properties of purine nucleotides, Dalton Trans., 2008, 5368-5377. |

|A. Mucha, W. Bal, M. Jeżowska-Bojczuk, Comparative studies of coordination properties of puromycin and puromycin aminonucleoside towards copper(II) ion, |

|J. Inorg. Biochem., 2008, 102, 46-52. |

|M. Cappanelli, E. Gaggelli, M. Jeżowska-Bojczuk, E. Molteni, A. Mucha, E. Porciatti, D. Valensin, G. Valensin, 1H- and 13C-NMR study of the complex |

|formed by copper (II) with the nucleoside antibiotic - sinefungin, J. Inorg. Biochem., 2007, 101, 1005-1012. |

|M. Jaworska, P. Lodowski, A. Mucha, W. Szczepanik, M. Cappanelli, G. Valensin, M. Jeżowska-Bojczuk, Characterization of copper(II) interactions with |

|sinefungin, a nucleoside antibiotic. Combined potentiometric, spectroscopic and DFT studies, Bioinorg. Chem. Applications, 2007, doi:10.1155/2007/53521. |

|A. Mucha, M. Cappanelli, W. Szczepanik, P. Kaczmarek, J. Skała, M. Jeżowska-Bojczuk, Influence of the physiologically widespread substances on the |

|oxidative activity of copper(II) complexes with sinefungin, a nucleoside antibiotic, J. Inorg. Biochem., 2006, 100, 178-185. |

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