IMD3 Faculty - University of Louisville
IMD3 Faculty
Paula J. Bates, Oncology/Brown Cancer Center
Douglas Borchman, Ophthalmology
Gabino Rafael Fernandez-Botran, Pathology
Sven-Ulrik Gorr, Biology
Thomas R. Hanley, Dean/Speed School
Kyung A. Kang, Chemical Engineering
Nancy C. Martin, Biochemistry & Molecular Biology
Muriel C. Maurer, Chemistry
Donald M. Miller, Brown Cancer Center
George R. Pack, Chemistry
William M. Pierce, Pharmacology
John F. Richardson, Chemistry
James W. Snyder, Pathology
Arno F. Spatola, Chemistry/ Biochemistry
K. Grant Taylor, Chemistry
John O. Trent, Brown Cancer Center
Roland Valdes, Jr., Pathology/Brown Cancer Center
James L. Wittliff, Biochemistry/ Brown Cancer Center
M. Cecilia Yappert, Chemistry
Organizing Committee
Arno F. Spatola
K. Grant Taylor
James L. Wittliff
Melody Grapperhaus
Institute for Molecular
Diversity and Drug Design
First Annual F3
Friday Fall Fest
November 8, 2002
The Cardinal Club
Simpsonville, KY
8:00 CONTINENTAL BREAKFAST
8:30 Welcome
8:45 IMD3: A Progress Report – Arno F. Spatola
9:15 Dr. Roland Valdes, Jr.
Saeed A. Jortani “Discovering New Biomarkers of CHF”
Mark W. Linder “Pharmacogenetics: New Developments”
9:45 Dr. Muriel C. Maurer
Giulia Isetti “Substitutions and Truncations Within the Factor XIII Activation Peptide Segment (28-41) Affect Interactions With the Thrombin Active Site”
Brian Turner “Evidence of Conformational Changes Upon Activation of Factor XIII”
10:15 BREAK
10:45 Dr. Douglas Borchman
Daxin Tang, Ph.D. “Lipids, the Lens and Cataract”
Li (Grace) Huang “Lipids and Dry Eyes”
11:15 Dr. James L. Wittliff
Sarah A. Andres “Assessment of xenoestrogen recognition by recombinant human estrogen receptors using ligand titration arrays”
Andrei S. Smolenkov “Estrogen receptor association with response element sequences of genes influenced by estrogens and their mimics”
11:45 DISCUSSION
12:00 LUNCH
1:00 Dr. Arno F. Spatola
Florence M. Brunel “Making drigs more soluble: Examination of alkylated C-sugars as bioconjugates”
Amit Galande “Targeting transcription factors with helicomimetics for cancer therapy”
1:30 Dr. Sven-Ulrik Gorr
Brigitte H. Fasciotto Dunn, Ph.D. “Drug abuse, neurogenesis and chromagranin A”
S. G. Venkatesh, Ph.D. “A new model for the pathogenesis of Sjogren’s syndrome”
2:00 Dr. Paula Bates
Allicia Girvan (Bates) “Mechanistic Studies of G-rich Oligonucleotides”
David Willson (Trent) “Structure Based Drug Design of Nucleolin Inhibitors”
2:30 DISCUSSION
2:45 BREAK
3:00 Instruments – Jortani, Maurer, Spatola,
and Wittliff
3:45 Closing – Dr. James L. Wittliff
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[pic][pic]
Afternoon Program
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