IMD3 Faculty - University of Louisville



IMD3 Faculty

Paula J. Bates, Oncology/Brown Cancer Center

Douglas Borchman, Ophthalmology

Gabino Rafael Fernandez-Botran, Pathology

Sven-Ulrik Gorr, Biology

Thomas R. Hanley, Dean/Speed School

Kyung A. Kang, Chemical Engineering

Nancy C. Martin, Biochemistry & Molecular Biology

Muriel C. Maurer, Chemistry

Donald M. Miller, Brown Cancer Center

George R. Pack, Chemistry

William M. Pierce, Pharmacology

John F. Richardson, Chemistry

James W. Snyder, Pathology

Arno F. Spatola, Chemistry/ Biochemistry

K. Grant Taylor, Chemistry

John O. Trent, Brown Cancer Center

Roland Valdes, Jr., Pathology/Brown Cancer Center

James L. Wittliff, Biochemistry/ Brown Cancer Center

M. Cecilia Yappert, Chemistry

Organizing Committee

Arno F. Spatola

K. Grant Taylor

James L. Wittliff

Melody Grapperhaus

Institute for Molecular

Diversity and Drug Design

First Annual F3

Friday Fall Fest

November 8, 2002

The Cardinal Club

Simpsonville, KY

8:00 CONTINENTAL BREAKFAST

8:30 Welcome

8:45 IMD3: A Progress Report – Arno F. Spatola

9:15 Dr. Roland Valdes, Jr.

Saeed A. Jortani “Discovering New Biomarkers of CHF”

Mark W. Linder “Pharmacogenetics: New Developments”

9:45 Dr. Muriel C. Maurer

Giulia Isetti “Substitutions and Truncations Within the Factor XIII Activation Peptide Segment (28-41) Affect Interactions With the Thrombin Active Site”

Brian Turner “Evidence of Conformational Changes Upon Activation of Factor XIII”

10:15 BREAK

10:45 Dr. Douglas Borchman

Daxin Tang, Ph.D. “Lipids, the Lens and Cataract”

Li (Grace) Huang “Lipids and Dry Eyes”

11:15 Dr. James L. Wittliff

Sarah A. Andres “Assessment of xenoestrogen recognition by recombinant human estrogen receptors using ligand titration arrays”

Andrei S. Smolenkov “Estrogen receptor association with response element sequences of genes influenced by estrogens and their mimics”

11:45 DISCUSSION

12:00 LUNCH

1:00 Dr. Arno F. Spatola

Florence M. Brunel “Making drigs more soluble: Examination of alkylated C-sugars as bioconjugates”

Amit Galande “Targeting transcription factors with helicomimetics for cancer therapy”

1:30 Dr. Sven-Ulrik Gorr

Brigitte H. Fasciotto Dunn, Ph.D. “Drug abuse, neurogenesis and chromagranin A”

S. G. Venkatesh, Ph.D. “A new model for the pathogenesis of Sjogren’s syndrome”

2:00 Dr. Paula Bates

Allicia Girvan (Bates) “Mechanistic Studies of G-rich Oligonucleotides”

David Willson (Trent) “Structure Based Drug Design of Nucleolin Inhibitors”

2:30 DISCUSSION

2:45 BREAK

3:00 Instruments – Jortani, Maurer, Spatola,

and Wittliff

3:45 Closing – Dr. James L. Wittliff

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Afternoon Program

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