The - EMCDDA home page | www.emcdda.europa.eu

The oocytes were voltage clamped at -60 mV, near the resting potential of the cells, and the drugs were applied for 60 seconds at a concentration of 10 μM. MDPV generated a cocaine-like outward hyperpolarising current compared with baseline; this contrasted to the inward depolarising current seen with mephedrone, methamphetamine and methcathinone. ................
................