QUANTITATIVE RISK ASSESSMENT OF OXYTETRACYCLINE AND ...

Furthermore the important features for antibacterial activity of the tetracycline group include the maintenance of this linear fused tetracycle naturally occurring stereochemical configuration at A- B ring junction and 4 dimethyl positions, conservation of the keto – etol system, aminogroup conservation of the keto enol system (positions 11, 12 and 12a) in proximity to the phenolic D ring. ................
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