ISMP Medication Safety Alert



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|10/15 |

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|10/15 |

|11/15 |

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|11/15 |

|09/15 |

|09/15 |

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|11/15 |

|09/15 |

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|10/15 |

11/15

[pic]A number of regulatory and product changes that occurred years ago may still be contributing to mix-ups between HYDROcodone-acetaminophen and oxyCODONE-acetaminophen combination products. For example, all approved opioid-acetaminophen combination products are now limited to 325 mg of acetaminophen or less. Avoid storing these next to each other. Consider tall man letters, bolding, or highlighting to differentiate the drug names. If the prescribed combination product is not available, the pharmacist should contact the prescriber. Review the prescription with the patient at the point-of-sale to help prevent mix-ups. 

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