Jordan University of Science & Technology



Jordan University of Science & Technology

Faculty of Dentistry

Dent 353 Oral Pathology

Second Semester 2008/2009

Course Description

This course consists of 3 credit hours taught in the second semester to third year dental student.

Course Objectives:

1. To acquire a basic understanding of main diseases in the following topics:

a) Infections of the oral mucosa.

b) Oral ulcerations and vesiculobullous diseases.

c) Diseases of the salivary glands.

d) Miscellaneous Disorders of Oral mucosa

e) Diseases of the temporomandibular joint.

f) Disorders of bone.

g) Odontomes and odontogenic tumors.

2. To be able to classify diseases according to the basic pathologic process.

3. To be familiar with the clinical, radiographic, and main histopathologic features of significant diseases of the oral and maxillofacial region in the above-mentioned topics.

4. To be able to make a differential diagnosis of oral lesions based on the knowledge received in the above-mentioned topics.

5. To be aware of the relative significance and basic management of each disease process.

Course Content:

a. Infections of the Oral Mucosa (3 lectures).

Viral Infections:

Herpetic stomatitis

Chickenpox and herpes zoster (shingles)

Herpangina

Hand, foot, and mouth disease

Infectious mononucleosis (glandular fever)

Measles

Cytomegalovirus

Bacterial Infections:

Necrotizing ulcerative gingivitis (NUG)

Noma (cancrum oris)

Actinomycosis

Syphilis

Tuberculosis

Fungal Infections:

Candida species and opportunistic infection

Classification of oral and perioral candidosis

Pseudomembranous candidosis (acute and chronic)

Erythematous candidosis (acute and chronic)

Chronic hyperplastic candidosis (candidal leukoplakia)

Candida-associated denture stomatitis chronic atrophic candidosis)

Candida-associated and other forms of angular cheilitis

Median rhomboid glossitis

Chronic mucocutaneous candidosis and oral manifestations of deep visceral mycoses

Zygomycosis (mucormycosis)*

Aspergillosis*

Human Immunodeficiency virus (HIV) and AIDS

Oral manifestations of HIV infection (oral candidosis, HIV-associated periodontal diseases, viral infections, hairy leukoplakia, Kaposi’s sarcoma, non-Hodgkin’s lymphoma, neurological disturbances, atypical ulceration, idiopathic thrombocytopenic purpura, HIV-associated salivary gland disease, oral pigmentation)

b. Oral Ulcerations and Vesiculobullous Diseases (3 lectures).

Classification of Oral Ulceration

Traumatic Ulceration

Recurrent Aphthous Stomatitis (RAS)

Clinical features of RAS

Etiology of RAS

Histopathological and immunological features of RAS

Behçet syndrome

Vesiculobullous Diseases

Classification

Pemphigus vulgaris

Erythema multiforme

Pemphigoid

Mucous membrane pemphigoid

Dermatitis herpetiformis

Linear IgA disease

Epidermolysis bullosa

Oral blood blisters (angina bullosa hemorrhagica)

c. Diseases of the Salivary Glands (3 lectures):

Developmental Anomalies

Aplasia

Atresia

Hetertopia

Sialadenitis

Bacterial sialadenitis

Viral sialadenitis

Postirradiation sialadenitis

Sarcoidosis

Sialadenitis of minor glands

Obstructive and Traumatic Lesions

Salivary calculi (sialoliths)

Necrotizing sialometaplasia

Sjögren’s Syndrome and Related Disorders

Sialadenosis

HIV-Associated Salivary Gland Disease

Salivary Gland Tumors

Classification

Adenomas (pleomorphic adenoma, Warthin tumor, basal cell adenoma, oncocytoma, canalicular adenoma, ductal papillomas)

Carcinomas (mucoepidermoid carcinoma, acinic cell carcinoma, adenoid cystic carcinoma, carcinoma ex pleomorhic adenoma and malignant mixed tumor, polymorphous low grade adenocarcinoma)

Age Changes in Salivary Glands

d. Miscellaneous Disorders of Oral mucosa

Fordyce’s Granules

Sublingual Varices

Lingual Tonsil, Foliate Papillitis

Geographic Tongue (Migratory Glossitis)

Orofacial Granulomatosis

Crohn’s Disease

Sarcoidosis

Pyostomatitis Vegetans

Progressive Systemic Sclerosis (Scleroderma)

Verruciform Xanthoma

Oral Submucous Fibrosis

Amyloidosis

Oral Pigmentation

Superficial staining of the mucosa

Black hairy tongue

Foreign bodies

Amalgam tattoo Melanin pigmentation-developmental causes

Heavy metal salts

Melanin pigmentation-acquired causes (Addison’s disease, pulmonary disease, HIV infection, chronic inflammation & lichen planus, drug-induced, idiopathic oral melanotic macule, lentigo simplex) sialadenitis

Neoplastic causes (melanoma in situ and melanoma)

Other endogenous pigments

Age Changes in the Oral Mucose.

e. Diseases of the temporomandibular joint:

Developmental disorders

Inflammatory disorders

Traumatic arthritis

Infective arthritis

Rheumatoid arthritis

Osteoarthritis

Functional disorders

Myofascial pain-dysfunction syndrome

Disc displacement

Loose bodies

Neoplasms

Age changes in the jaws and the temporomandibular joint

Trismus and dislocation

f. Disorders of Bone (6 lectures)

Inherited and Developmental Disorders of Bone

Osteogenesis imperfecta

Osteopetrosis (marble bone disease)

Cleidocranial dysplasia

Achondroplasia

Fibro-osseous lesions

Fibrous dysplasia of bone

Cemento-osseous dysplasia

Cherubism

Healing of Bone

Healing of an extraction socket

Osseointegrated implants

Inflammatory Diseases of Bone

Alveolar osteitis (dry socket)

Focal scelrosing osteitis

Osteomyelitis

Radiation injury and osteoradionecrosis

Metabolic and Endocrine Disorders of Bone

Osteoporosis

Primary hyperparathyroidism

Secondary hyperparathyroidism

Rickets and osteomalacia

Acromegaly

Paget’s Disease of Bone

Central Giant Cell Granuloma

Tori and Exostoses

Dense bone island

Tumors of Bone

Osteoma

Osteoblastoma

Osteosarcoma

Chondroma

Chondrosarcoma

Myeloma

Cemento-ossifying fibroma

Langerhans Cell Histiocytosis

Hemangioma of Bone

Metastatic Tumor

g. Odontomes and Odontogenic Tumors (2 lectures).

Classification

Odontomes

Invaginated odontome

Evaginated odontome

Enamel pearl

Complex odontome

Compound odontome

Odontogenic Tumors

Ameloblastoma

Unicystic ameloblastoma

Peripheral ameloblastoma

Squamous odontogenic tumor

Calcifying epithelial odontogenic tumor

Ameloblastic fibroma

Adenomatoid odontogenic tumor

Calcifying cystic odontogenic tumor (calcifying odontogenic cyst)

Odontogenic fibroma and myxoma

Cementoblastoma

Malignant odontogenic tumors (malignant ameloblastoma, ameloblastic carcinoma, primary intraosseous squmaous cell carcinoma, clear cell odontogenic carcinoma, malignant change in odontogenic cysts, odontogenic sarcomas)

Tumors of Debatable Origin

Congenital epulis

Laboratory Sessions:

In the form of discussion with students on computerized images of clinical, radiographic and histopathologic features.

Lab 1: Infections of Oral Mucosa

Lab 2: Oral Ulcerations & Vesiculobullous Diseases

Lab 3: Diseases of Salivary Glands Disorders of Bone II

Lab 4: Miscellaneous Disorders of Oral mucosa

Lab 5: Disorders of Bone I

Lab 6: Disorders of Bone II

Lab 7: Odontomes and Odontogenic Tumors

References:

Textbook:

1. Oral Pathology by Soames & Southam, Oxford University Press, 4rth edition, 2005

2. Useful websites:





















Jordan University of Science & Technology

Faculty of Dentistry

Dent 356 Oral Pathology 2

Second Semester 2008-2009

Course Outline

Course coordinator: Dr. Rima Safadi

Lecturers: Dr. Rima Safadi and Dr. Huda Hammad.

Textbook: Oral Pathology by Soames & Southam, Oxford University Press, 4th Edition 2005.

Time: Monday and Wednesday: 12:45- 2:15 pm

Place: Nursing Hall.

Office Hours: Wednesday: 2:15- 3:15 pm after each lecture for each lecturer, Post graduate clinics

Students are not allowed to miss more than 10% of the total hours of the course without an excuse accepted by the dean.

If the student missed more than 10% of the total course hours without an excuse accepted by the dean, he/she will not be allowed to take the rest of the exams in the course.

10% of course hours= 2.6 sessions

Grading:

Midterm exam: 40/100 divided as follows: 13 online practical, 27 theory.

Final exam: 60/100, including 20/100 online practical.

|ٌLecturer |Lecture |Date |Day |Week |

|Dr. Safadi |Introduction |16/2 |Mon |1 |

| |No Lab |18/2 |Wed | |

|Dr. Safadi |Infections of the Oral Mucosa |23/2 |Mon |2 |

|Dr. Safadi |Infections of the Oral Mucosa |25/2 |Wed | |

|Dr. Safadi |Infections of the Oral Mucosa |2/3 |Mon |3 |

|Dr. Safadi |LAB 1 |4/3 |Wed | |

|Dr. Safadi |Oral Ulcerations& Vesiculobullous Diseases |9/3 |Mon |4 |

|Dr. Safadi |Oral Ulcerations& Vesiculobullous Diseases |11/3 |Wed | |

|Dr. Safadi |Oral Ulcerations& Vesiculobullous Diseases |16/3 |Mon |5 |

|Dr. Safadi |LAB 2 |18/3 |Wed | |

|Dr. Hammad |Miscellaneous disorders |23/3 |Mon |6 |

|Dr. Hammad |LAB 3 |25/3 |Wed | |

|Dr. Hammad |Disorders of Salivary Glands |30/3 |Mon |7 |

|Dr. Hammad |Disorders of Salivary Glands |1/4 |Wed | |

| |No lecture |6/4 |Mon |8 |

| |Midterm exam |8/4 |Wed | |

|Dr. Hammad |Disorders of Salivary Glands |13/4 |Mon |9 |

|Dr. Hammad |LAB 4 |15/4 |Wed | |

|Dr. Hammad |Odontomes and Odontogenic Tumors |20/4 |Mon | |

| | | | |10 |

|Dr. Hammad |Odontomes and Odontogenic Tumors |22/4 |Wed | |

|Dr. Hammad |LAB 5 |27/4 |Mon |11 |

|Dr. Hammad |Disorders of Bone |29/4 |Wed | |

|Dr. Hammad |Disorders of Bone |4/5 |Mon |12 |

|Dr. Hammad |Disorders of Bone |6/5 |Wed | |

|Dr.Hammad |LAB 6 |11/5 |Mon |13 |

|Dr. Safadi |Disorders of Bone |13/5 |Wed | |

|Dr. Safadi |Disorders of Bone |18/5 |Mon |14 |

|Dr. Safadi |Disorders of Bone |20/5 |Wed | |

|Holiday |Holiday |25/5 |Mon |15 |

|Dr. Safadi |LAB 7 |27/5 |Wed | |

|Dr. Hammad |Disorders of TMJ |1/6 |Mon |16 |

Dent 356 Oral Pathology 2 syllabus, second semester 2009

Grading

Midterm exam: 40/100 divided as 13 online practical, 27 theory.

Final exam: 60/100, including 20/100 online practical.

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