Jordan University of Science & Technology
Jordan University of Science & Technology
Faculty of Dentistry
Dent 353 Oral Pathology
Second Semester 2008/2009
Course Description
This course consists of 3 credit hours taught in the second semester to third year dental student.
Course Objectives:
1. To acquire a basic understanding of main diseases in the following topics:
a) Infections of the oral mucosa.
b) Oral ulcerations and vesiculobullous diseases.
c) Diseases of the salivary glands.
d) Miscellaneous Disorders of Oral mucosa
e) Diseases of the temporomandibular joint.
f) Disorders of bone.
g) Odontomes and odontogenic tumors.
2. To be able to classify diseases according to the basic pathologic process.
3. To be familiar with the clinical, radiographic, and main histopathologic features of significant diseases of the oral and maxillofacial region in the above-mentioned topics.
4. To be able to make a differential diagnosis of oral lesions based on the knowledge received in the above-mentioned topics.
5. To be aware of the relative significance and basic management of each disease process.
Course Content:
a. Infections of the Oral Mucosa (3 lectures).
Viral Infections:
Herpetic stomatitis
Chickenpox and herpes zoster (shingles)
Herpangina
Hand, foot, and mouth disease
Infectious mononucleosis (glandular fever)
Measles
Cytomegalovirus
Bacterial Infections:
Necrotizing ulcerative gingivitis (NUG)
Noma (cancrum oris)
Actinomycosis
Syphilis
Tuberculosis
Fungal Infections:
Candida species and opportunistic infection
Classification of oral and perioral candidosis
Pseudomembranous candidosis (acute and chronic)
Erythematous candidosis (acute and chronic)
Chronic hyperplastic candidosis (candidal leukoplakia)
Candida-associated denture stomatitis chronic atrophic candidosis)
Candida-associated and other forms of angular cheilitis
Median rhomboid glossitis
Chronic mucocutaneous candidosis and oral manifestations of deep visceral mycoses
Zygomycosis (mucormycosis)*
Aspergillosis*
Human Immunodeficiency virus (HIV) and AIDS
Oral manifestations of HIV infection (oral candidosis, HIV-associated periodontal diseases, viral infections, hairy leukoplakia, Kaposi’s sarcoma, non-Hodgkin’s lymphoma, neurological disturbances, atypical ulceration, idiopathic thrombocytopenic purpura, HIV-associated salivary gland disease, oral pigmentation)
b. Oral Ulcerations and Vesiculobullous Diseases (3 lectures).
Classification of Oral Ulceration
Traumatic Ulceration
Recurrent Aphthous Stomatitis (RAS)
Clinical features of RAS
Etiology of RAS
Histopathological and immunological features of RAS
Behçet syndrome
Vesiculobullous Diseases
Classification
Pemphigus vulgaris
Erythema multiforme
Pemphigoid
Mucous membrane pemphigoid
Dermatitis herpetiformis
Linear IgA disease
Epidermolysis bullosa
Oral blood blisters (angina bullosa hemorrhagica)
c. Diseases of the Salivary Glands (3 lectures):
Developmental Anomalies
Aplasia
Atresia
Hetertopia
Sialadenitis
Bacterial sialadenitis
Viral sialadenitis
Postirradiation sialadenitis
Sarcoidosis
Sialadenitis of minor glands
Obstructive and Traumatic Lesions
Salivary calculi (sialoliths)
Necrotizing sialometaplasia
Sjögren’s Syndrome and Related Disorders
Sialadenosis
HIV-Associated Salivary Gland Disease
Salivary Gland Tumors
Classification
Adenomas (pleomorphic adenoma, Warthin tumor, basal cell adenoma, oncocytoma, canalicular adenoma, ductal papillomas)
Carcinomas (mucoepidermoid carcinoma, acinic cell carcinoma, adenoid cystic carcinoma, carcinoma ex pleomorhic adenoma and malignant mixed tumor, polymorphous low grade adenocarcinoma)
Age Changes in Salivary Glands
d. Miscellaneous Disorders of Oral mucosa
Fordyce’s Granules
Sublingual Varices
Lingual Tonsil, Foliate Papillitis
Geographic Tongue (Migratory Glossitis)
Orofacial Granulomatosis
Crohn’s Disease
Sarcoidosis
Pyostomatitis Vegetans
Progressive Systemic Sclerosis (Scleroderma)
Verruciform Xanthoma
Oral Submucous Fibrosis
Amyloidosis
Oral Pigmentation
Superficial staining of the mucosa
Black hairy tongue
Foreign bodies
Amalgam tattoo Melanin pigmentation-developmental causes
Heavy metal salts
Melanin pigmentation-acquired causes (Addison’s disease, pulmonary disease, HIV infection, chronic inflammation & lichen planus, drug-induced, idiopathic oral melanotic macule, lentigo simplex) sialadenitis
Neoplastic causes (melanoma in situ and melanoma)
Other endogenous pigments
Age Changes in the Oral Mucose.
e. Diseases of the temporomandibular joint:
Developmental disorders
Inflammatory disorders
Traumatic arthritis
Infective arthritis
Rheumatoid arthritis
Osteoarthritis
Functional disorders
Myofascial pain-dysfunction syndrome
Disc displacement
Loose bodies
Neoplasms
Age changes in the jaws and the temporomandibular joint
Trismus and dislocation
f. Disorders of Bone (6 lectures)
Inherited and Developmental Disorders of Bone
Osteogenesis imperfecta
Osteopetrosis (marble bone disease)
Cleidocranial dysplasia
Achondroplasia
Fibro-osseous lesions
Fibrous dysplasia of bone
Cemento-osseous dysplasia
Cherubism
Healing of Bone
Healing of an extraction socket
Osseointegrated implants
Inflammatory Diseases of Bone
Alveolar osteitis (dry socket)
Focal scelrosing osteitis
Osteomyelitis
Radiation injury and osteoradionecrosis
Metabolic and Endocrine Disorders of Bone
Osteoporosis
Primary hyperparathyroidism
Secondary hyperparathyroidism
Rickets and osteomalacia
Acromegaly
Paget’s Disease of Bone
Central Giant Cell Granuloma
Tori and Exostoses
Dense bone island
Tumors of Bone
Osteoma
Osteoblastoma
Osteosarcoma
Chondroma
Chondrosarcoma
Myeloma
Cemento-ossifying fibroma
Langerhans Cell Histiocytosis
Hemangioma of Bone
Metastatic Tumor
g. Odontomes and Odontogenic Tumors (2 lectures).
Classification
Odontomes
Invaginated odontome
Evaginated odontome
Enamel pearl
Complex odontome
Compound odontome
Odontogenic Tumors
Ameloblastoma
Unicystic ameloblastoma
Peripheral ameloblastoma
Squamous odontogenic tumor
Calcifying epithelial odontogenic tumor
Ameloblastic fibroma
Adenomatoid odontogenic tumor
Calcifying cystic odontogenic tumor (calcifying odontogenic cyst)
Odontogenic fibroma and myxoma
Cementoblastoma
Malignant odontogenic tumors (malignant ameloblastoma, ameloblastic carcinoma, primary intraosseous squmaous cell carcinoma, clear cell odontogenic carcinoma, malignant change in odontogenic cysts, odontogenic sarcomas)
Tumors of Debatable Origin
Congenital epulis
Laboratory Sessions:
In the form of discussion with students on computerized images of clinical, radiographic and histopathologic features.
Lab 1: Infections of Oral Mucosa
Lab 2: Oral Ulcerations & Vesiculobullous Diseases
Lab 3: Diseases of Salivary Glands Disorders of Bone II
Lab 4: Miscellaneous Disorders of Oral mucosa
Lab 5: Disorders of Bone I
Lab 6: Disorders of Bone II
Lab 7: Odontomes and Odontogenic Tumors
References:
Textbook:
1. Oral Pathology by Soames & Southam, Oxford University Press, 4rth edition, 2005
2. Useful websites:
Jordan University of Science & Technology
Faculty of Dentistry
Dent 356 Oral Pathology 2
Second Semester 2008-2009
Course Outline
Course coordinator: Dr. Rima Safadi
Lecturers: Dr. Rima Safadi and Dr. Huda Hammad.
Textbook: Oral Pathology by Soames & Southam, Oxford University Press, 4th Edition 2005.
Time: Monday and Wednesday: 12:45- 2:15 pm
Place: Nursing Hall.
Office Hours: Wednesday: 2:15- 3:15 pm after each lecture for each lecturer, Post graduate clinics
Students are not allowed to miss more than 10% of the total hours of the course without an excuse accepted by the dean.
If the student missed more than 10% of the total course hours without an excuse accepted by the dean, he/she will not be allowed to take the rest of the exams in the course.
10% of course hours= 2.6 sessions
Grading:
Midterm exam: 40/100 divided as follows: 13 online practical, 27 theory.
Final exam: 60/100, including 20/100 online practical.
|ٌLecturer |Lecture |Date |Day |Week |
|Dr. Safadi |Introduction |16/2 |Mon |1 |
| |No Lab |18/2 |Wed | |
|Dr. Safadi |Infections of the Oral Mucosa |23/2 |Mon |2 |
|Dr. Safadi |Infections of the Oral Mucosa |25/2 |Wed | |
|Dr. Safadi |Infections of the Oral Mucosa |2/3 |Mon |3 |
|Dr. Safadi |LAB 1 |4/3 |Wed | |
|Dr. Safadi |Oral Ulcerations& Vesiculobullous Diseases |9/3 |Mon |4 |
|Dr. Safadi |Oral Ulcerations& Vesiculobullous Diseases |11/3 |Wed | |
|Dr. Safadi |Oral Ulcerations& Vesiculobullous Diseases |16/3 |Mon |5 |
|Dr. Safadi |LAB 2 |18/3 |Wed | |
|Dr. Hammad |Miscellaneous disorders |23/3 |Mon |6 |
|Dr. Hammad |LAB 3 |25/3 |Wed | |
|Dr. Hammad |Disorders of Salivary Glands |30/3 |Mon |7 |
|Dr. Hammad |Disorders of Salivary Glands |1/4 |Wed | |
| |No lecture |6/4 |Mon |8 |
| |Midterm exam |8/4 |Wed | |
|Dr. Hammad |Disorders of Salivary Glands |13/4 |Mon |9 |
|Dr. Hammad |LAB 4 |15/4 |Wed | |
|Dr. Hammad |Odontomes and Odontogenic Tumors |20/4 |Mon | |
| | | | |10 |
|Dr. Hammad |Odontomes and Odontogenic Tumors |22/4 |Wed | |
|Dr. Hammad |LAB 5 |27/4 |Mon |11 |
|Dr. Hammad |Disorders of Bone |29/4 |Wed | |
|Dr. Hammad |Disorders of Bone |4/5 |Mon |12 |
|Dr. Hammad |Disorders of Bone |6/5 |Wed | |
|Dr.Hammad |LAB 6 |11/5 |Mon |13 |
|Dr. Safadi |Disorders of Bone |13/5 |Wed | |
|Dr. Safadi |Disorders of Bone |18/5 |Mon |14 |
|Dr. Safadi |Disorders of Bone |20/5 |Wed | |
|Holiday |Holiday |25/5 |Mon |15 |
|Dr. Safadi |LAB 7 |27/5 |Wed | |
|Dr. Hammad |Disorders of TMJ |1/6 |Mon |16 |
Dent 356 Oral Pathology 2 syllabus, second semester 2009
Grading
Midterm exam: 40/100 divided as 13 online practical, 27 theory.
Final exam: 60/100, including 20/100 online practical.
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