Theranostics
Statins lower cholesterol levels by inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA), the main regulatory step in the cholesterol biosynthesis pathway. Applied statins to lower brain cholesterol are thought to require lipophilic properties to be able to cross the BBB and affect brain cholesterol metabolism (Thelen et al. 2005). ................
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