MRS. MCINTYRE



Genetics Part (B) ReviewDefine the following. Give an example where possible:EpistasisPolygenic inheritanceLinkageLethal genesModifier genesAutosomesSex chromosomesPedigreeKaryotypeUse the following information for the next two questions:Human blood type is determined by co-dominant alleles. There are three different alleles, known as IA, IB, and i. The IA and IB alleles are co-dominant, and the i allele is recessive. List all possible phenotypes and genotypes. How many are there of each?A woman with type A blood and a man with type B blood could potentially have offspring with which of the following blood types?Type AType BType OType ABAll of the aboveWhat are the possible blood types of the offspring of a cross between individuals that are type AB and type O? (Hint: blood type O is recessive)AB or OA, B, or OA or BA, B, AB, or OA, B, or ABWhat blood type is the universal donor? Which is the universal recipient? (not in notes)In mice, color is dominant (C) and no pigment is recessive (c). A black coat in mice is dominant (B) to a brown coat (b). What is the F1 phenotype ratio if a heterozygous black mouse is mated to a white mouse (bbcc)?How do we account for the variation in skin colors in humans?Red-green color-blindness is a sex-linked recessive disorder. Determine the expected genotypic and phenotypic ratios from crossing a normal male and a female who is a carrier of color-blindness.Hemophilia is a sex-linked recessive disorder that prevents the blood from clotting. Determine the genotypic and phenotypic rations from crossing a male with hemophilia and a female who is a carrier for hemophilia.A male who is color-blind marries a normal female (homozygous). The male is homozygous for hanging free earlobes and the female has attached earlobes. What would the F1 and F2 phenotypic ratios be?Why are sex-linked recessive disorders more common in males than in females? Explain with reference to the X chromosome.Draw a possible pedigree chart for autosomal dominant and autosomal recessive inheritance.Using the Pedigree below, determine the following:What type of inheritance pattern is displayed by the pedigree below?List the possible genotypes for each individual.What are the 6 types of chromosomal mutations? List and draw each.What are the 2 tests used to examine the chromosomes of fetal cells? What are the risks?List 4 syndrome’s caused by Non-disjunction. Be sure to mention the genotype’s of each.What disorder does the person’s karyotype below indicate?1076325170561000 ................
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