VA Drug Class Review: Phosphodiesterase Type 5 Inhibitors ...

All the PDE5 inhibitors selectively inhibit PDE5, thus preventing the breakdown of cGMP and enhancing or restoring the natural erectile response. Other types of PDE, 1 – 11, are found through out the body and provide a number of different functions (see Table 2). The 3 PDE5 inhibitors differ in their selectivity as shown in Table 3. ................
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