National PBM Drug Monograph
Tetrabenazine is metabolized through the CYP2D6 P450 liver enzyme. This enzyme is highly polymorphic which affects the metabolism of medications going through this pathway. ... 12.4) (range 37-76 years). The mean final duration of treatment at post-TBZ evaluation was 5.9 (3.3) months (range 2-11 months) with a mean final dose of 62.5 (37.4) mg ... ................
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