Systemic Lupus Erythematosus Overview
[Pages:44]Systemic Lupus
Erythematosus Overview
Clinical presentation, pathophysiology, and therapeutic strategies over the course of disease
Systemic Lupus Erythematosus (SLE)
? An inflammatory, multisystem, autoimmune disease of unknown etiology with protean clinical and laboratory manifestations and a variable course and prognosis
? Lupus can be a mild disease, a severe and life-threatening illness, or anything in between
Clinical Manifestations of SLE-- Important Concepts
? The diversity of clinical symptoms in SLE is great, and all organ systems are vulnerable
? Different ethnic backgrounds are associated with differences in disease prevalence and severity
? Disease is characterized by periods of flare and remission and can culminate in irreversible end-organ damage
Video of Dr. Graciela Alarc?n
The University of Alabama at Birmingham
Introduction
? Epidemiology ? Diagnosis ? Pathogenesis ? Mortality ? Therapeutic principles
Epidemiology
? Prevalence: 2?140/100,000 worldwide but as high as 207/100,000
? Incidence: 1?10/100,000 worldwide
? Population at highest risk:
? Women in their reproductive years
? Female:male ratio is approximately 9:1 postpuberty and premenopausal
? Variation in race/ethnicity: More common in Black (3-6x), Hispanic and Native American (2?3x), and Asian (2x) populations
? Cost: There are direct costs associated with treatment (eg, $100 billion in healthcare cost associated with autoimmune diseases) and indirect cost related to lost productivity and wages
Video of Dr. Graciela Alarc?n
The University of Alabama at Birmingham
................
................
In order to avoid copyright disputes, this page is only a partial summary.
To fulfill the demand for quickly locating and searching documents.
It is intelligent file search solution for home and business.
Related download
- systemic lupus erythematosus overview
- the progressive systemic sclerosis systemic lupus
- undifferentiated connective tissue disease and
- rehab 401 study guide exam 2
- ultraviolet light mediated induction of systemic lupus
- peripheral vascular disease musc
- gout and other crystal arthopathies
- patient care school of medicine
Related searches
- systemic polymyositis
- skin lupus vs systemic lupus
- systemic sclerosis polymyositis overlap
- systemic sclerosis polymyositis symptoms
- polymyositis systemic sclerosis overlap syndrome
- systemic lupus erythematosus diagnosis
- discoid lupus erythematosus symptoms
- discoid lupus erythematosus treatment
- drug induced systemic lupus erythematosus
- systemic lupus erythematosus
- systemic lupus symptoms
- systemic lupus erythematosus symptom