Treating Non-Hodgkin Lymphoma

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Treating Non-Hodgkin Lymphoma

If you've been diagnosed with non-Hodgkin lymphoma (NHL), your cancer care team will discuss your options with you. It's important to weigh the benefits of each treatment option against the possible risks and side effects. How is non-Hodgkin lymphoma treated? Depending on the type and stage (extent) of the lymphoma and other factors, treatment options for people with NHL might include:

q Chemotherapy for Non-Hodgkin Lymphoma q Immunotherapy for Non-Hodgkin Lymphoma q Targeted Drug Therapy for Non-Hodgkin Lymphoma q Radiation Therapy for Non-Hodgkin Lymphoma q High-Dose Chemotherapy and Stem Cell Transplant for Non-Hodgkin Lymphoma q Surgery for Non-Hodgkin Lymphoma

Common treatment approaches Treatment approaches for NHL depend on the type of lymphoma and how advanced it is, as well as your health and other factors. Another important part of treatment for many people is palliative or supportive care. This can help prevent or treat problems such as infections, low blood cell counts, or some symptoms caused by the lymphoma.

q Treating B-Cell Non-Hodgkin Lymphoma q Treating T-Cell Non-Hodgkin Lymphoma q Treating HIV-Associated Lymphoma

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q Palliative and Supportive Care for Non-Hodgkin Lymphoma

Who treats non-Hodgkin lymphoma? You may have different types of doctors on your treatment team. These doctors could include:

q A medical oncologist or hematologist: a doctor who treats lymphoma with chemotherapy, immunotherapy, and targeted therapy

q A radiation oncologist: a doctor who treats cancer with radiation therapy q A bone marrow transplant doctor: a doctor who specializes in treating cancer or

other diseases with bone marrow or stem cell transplants

You might have many other specialists on your treatment team as well, including physician assistants (PAs), nurse practitioners (NPs), nurses, nutrition specialists, pharmacists, social workers, and other health professionals.

q Health Professionals Who Are Part of a Cancer Care Team

Making treatment decisions It's important to discuss all of your treatment options, including their goals and possible side effects, with your doctors to help make the decision that best fits your needs. In choosing a treatment plan, consider your health and the type and stage of the lymphoma. It's also very important to ask questions if there is anything you're not sure about. If time permits, it is often a good idea to seek a second opinion. A second opinion can give you more information and help you feel more confident about the treatment plan you choose.

q Questions to Ask About Non-Hodgkin Lymphoma q Seeking a Second Opinion

Thinking about taking part in a clinical trial Clinical trials are carefully controlled research studies that are done to get a closer look at promising new treatments or procedures. Clinical trials are one way to get state-of-

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the art cancer treatment. In some cases they may be the only way to get access to newer treatments. They are also the best way for doctors to learn better methods to treat cancer.

If you would like to learn more about clinical trials that might be right for you, start by asking your doctor if your clinic or hospital conducts clinical trials.

q Clinical Trials

Considering complementary and alternative methods

You may hear about alternative or complementary methods to relieve symptoms or treat your cancer that your doctors haven't mentioned. These methods can include vitamins, herbs, and special diets, or other methods such as acupuncture or massage, to name a few.

Complementary methods are treatments that are used along with your regular medical care. Alternative treatments are used instead of standard medical treatment. Although some of these methods might be helpful in relieving symptoms or helping you feel better, many have not been proven to work. Some might even be harmful.

Be sure to talk to your cancer care team about any method you are thinking about using. They can help you learn what is known (or not known) about the method, which can help you make an informed decision.

q Complementary and Integrative Medicine

Help getting through cancer treatment

People with cancer need support and information, no matter what stage of illness they may be in. Knowing all of your options and finding the resources you need will help you make informed decisions about your care.

Whether you are thinking about treatment, getting treatment, or not being treated at all, you can still get supportive care to help with pain or other symptoms. Communicating with your cancer care team is important so you understand your diagnosis, what treatment is recommended, and ways to maintain or improve your quality of life.

Different types of programs and support services may be helpful, and they can be an important part of your care. These might include nursing or social work services, financial aid, nutritional advice, rehab, or spiritual help.

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The American Cancer Society also has programs and services - including rides to treatment, lodging, and more - to help you get through treatment. Call our Cancer Knowledge Hub at 1-800-227-2345 and speak with one of our caring, trained cancer helpline specialists. Or, if you prefer, you can use our chat feature on to connect with one of our specialists.

q Palliative Care q Programs & Services

Choosing to stop treatment or choosing no treatment at all

For some people, when treatments have been tried and are no longer controlling the cancer, it could be time to weigh the benefits and risks of continuing to try new treatments. Whether or not you continue treatment, there are still things you can do to help maintain or improve your quality of life.

Some people, especially if the cancer is advanced, might not want to be treated at all. There are many reasons you might decide not to get cancer treatment, but it's important to talk to your doctors as you make that decision. Remember that even if you choose not to treat the cancer, you can still get supportive care to help with pain or other symptoms.

q If Cancer Treatments Stop Working

The treatment information given here is not official policy of the American Cancer Society and is not intended as medical advice to replace the expertise and judgment of your cancer care team. It is intended to help you and your family make informed decisions, together with your doctor. Your doctor may have reasons for suggesting a treatment plan different from these general treatment options. Don't hesitate to ask your cancer care team any questions you may have about your treatment options.

Chemotherapy for Non-Hodgkin Lymphoma

Chemotherapy (chemo) is the use of anti-cancer drugs that are usually injected into a

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vein (IV) or taken by mouth. Chemo enters the bloodstream and reaches almost all areas of the body, making this treatment very useful for lymphoma.

q When might chemo be used? q Which chemo drugs are used to treat non-Hodgkin lymphoma? q Intrathecal chemo q Possible side effects q Other drugs used to treat lymphoma q More information about chemotherapy

When might chemo be used?

Chemo is the main treatment for most people with non-Hodgkin lymphoma (NHL). Depending on the type1 and the stage2 of the lymphoma, chemo may be used alone or combined with other treatments, such as immunotherapy drugs or radiation therapy.

Which chemo drugs are used to treat non-Hodgkin lymphoma?

Many chemo drugs are useful in treating lymphoma. Often, several drugs are combined. The number of chemo drugs, their doses, and the length of treatment depend on the type and stage of the lymphoma. Here are some of the drugs more commonly used to treat lymphoma (divided into groups based on how they work):

Alkylating agents

q Cyclophosphamide q Chlorambucil q Bendamustine q Ifosfamide

Corticosteroids

q Prednisone q Dexamethasone

Platinum drugs

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