وزارة الصحة الفلسطينية - الإدارة العامة للصيدلة



Choose the correct answer for questions (1-90:Question 1-4:M.A. 35 years old female, her medical history include ongoing asthma, allergic rhinitis, gastroesophageal reflex disease (GERD), and juvenile arthritis.Her medication history indicates that she is currently taking the following medications:Celecoxib 200 mg cap.Cisapride 10 mg cap.Ratadine 150 mg tab.Cetirizine tab.Montelukast 10 mg tab.Which of medication should be taken with food, to enhance their absorption?CisaprideCetirizineCelecoxibRatadineNone of the aboveWhich medications are being taken for asthma and allergic reaction?CisaprideCetirizineMontelukast RatadineB & CWhich drugs are being used to treat her arthritis?CisaprideCetirizineCelecoxibRatadineNone of the aboveWhich drugs are being used to treat her (GERD)?CisaprideCetirizineMontelukast RatadineA & DWhich of the following cardiovascular agent is classified as a glycoside?NifedipineDigoxinFlecainideChlestyramineWarfarinMyopathy is an adverse effect of all the following agents except:Atorvastatin.SimvastatineRosuvastatineGemfibrozilColestipolRectal suppositories intended for adult use usually weight approximately:1 g2 g3 g4 g5 gWhich of the following insulins can be administered intravenously?Regular insulinIsophane insulin (NPH)Protamine zinc insulin (PZT)Semilent insulinUltralente insulinAll of the following drugs may enhance breast milk production by increasing prolactinHaloperidolMethyldopaMetoclopramideBromocriptineTheophyllineIn the emergency department, the preferred first line therapy for asthma exacerbation is:TheophyllineBeta-agonistCorticosteroidCromolyn sodiumAntihistamine The active ingredient in Rizalt tablet is:RizatriptanPregabalinAmlodipineDuloxetineTinidazoleThe manufacturer of Rizalt is:MSDPfizerNovartisLeoLillyRizalt is indicated in:HypertensionDiabetes mellitusHypothyroidismHeart failure Migraine attacksThe medicine which have same active ingredient of cialis is:ViagraSiafilSinagraV-careA & C& DDiclofenac-sodium is the active ingredient of:AnaflamVoltarenMesulidTramalNone of the aboveUsed in the treatment of herpes zoster:AcyclovirDimethindeneLoratidineZinc oxideNone of the above Used for the treatment of anaerobic bacterial infectionGentamicinFucidic acidMetronidazole CephalexinNone of the aboveOne of the following substances is soluble in water:TetracyclineParacetamolAscorbic acidVitamin KIndomethacin Used in alopecia treatment:EnalaprilClonidineHydralazineAtenololMinoxidilClassified as controlled drug:IndomethacinEtodalacNimesulidRivotrilLamotrigine Used in fungal infection treatment:Atorvastatin MetronidazoleItraconazoleClindamycinNeomycinUsed in polycystic ovarian syndrome (POS)GlimeprideExenatideMetforminGlibenclamideNone of the abovePantinol plus ? cream is manufactured by:Beirzeit (BPC)GamaSandozPharmacareNovartisContains bromocriptine as active ingredient:LactoparParilacParlodelA & B & CNone of the aboveAll of these statements about (Pred-forte?) eye drops are true except:Used in fungal infection treatmentContains prednisolone as an active ingredientUsed with caution in glaucoma patientNot to be used more than 2 weeksManufactured by allergen companyAll of these statements about Trufen are true except:Can cause peptic ulcer Must be used with caution in hypertensive patients Can cause addictionAvailable as 200, 400, 600 mg strengths Manufactured by Jepharm(-40) Celsius degree is equal to – 60 Fahrenheit60 Fahrenheit80 Fahrenheit100 Fahrenheit40 FahrenheitAll of these statements about paracetamol is true except:Category B drugs, so it is safe during pregnancy150 mg strength is used for infantsHepatitis is the main complication from paracetamol overdose Has anti-inflammatory effectAcetylcysteine is the antidote for paracetamol overdose The medicine used to treat heparin overdose is:High dose of aspirinAtropine sulfateVitamin KParacetamolProtamin sulfateOne of these following antibiotics can be used in pregnancy:TetracyclineSulfamethoxazole-trimethoprimCiprofloxacinGentamicinCefuroxime Opioids are used as all of the following agents exceptAntitussivesAnalgesics Anti-inflammatory Antidiarrheals Preanesthetic medications Which of the following choices would be most appropriate in treating nausea and vomiting associated with motion sickness?Diphenhydramine BrompheniramineOndansetronOmeprazoleRanitidine Which of the following antiulcer medications is most likely to cause drug interaction and endocrine side effectsRanitidine OmeprazoleLansoprazoleCimetidineFamotidineThe selective cyclooxygenase (COX) 2 inhibitors have been associated with which of the following adverse drug reactions?Severe ischemic colitisTorsade des pointes Cardiovascular thrombotic eventsAcute liver failure Churg-Strauss syndromeBC has an upper respiratory infection. Two years ago she experienced an episode of bronchospasm after penicillin therapy. Current cultures are positive for a strain of Streptococcus pneumonia that is sensitive to all of the following drugs. Which of these drugs would be the best choice for this patient? Amoxicillin/ clavulanateAzithrimycinAmpicillinCefaclorCefdinir Which of the following medications would be considered first-line monotherapy for an acute episode of mania?GabapentinLithiumLamotrigineHaloperidolSertralineOsteoporosis is associated with the use of which of the following drugs used in rheumatoid arthritis (RA).Leflunomide PrednisoneMethotrexate PenicillamineHydroxychloroquine Potential adverse effects associated with aspirin include all of the following except:Gastrointestinal ulcerationRenal dysfunction Enhanced methotrexate toxicity Cardiac arrhythmiasHypersensitivity asthma.All of the following are correct regarding infection prophylaxis in an organ transplant patient except:Trimethoprime-sulfamethoxazole for pneumocytiscarinii pneumonia prophylaxisNystatin for fungal infectionOral acyclovir for herpes simplexClotrimazole troche for oral thrushLevofloxacin for urinary tract infectionTwo most important sites for drug elimination:Pulmonary and liverLiver and GITKidney and liverSkin and liverPulmonary and kidneyFactors which affect a drug’s volume of distributionPatient’s genderPatient’s ageDrug pkaExtent of drug-plasma protein bindingAll of the aboveEC 50 mainly reflexes a drugs:Maximal effectPotencyLethalityEase of eliminationSafetyXerostomia can result from the following drugs side effectsAntidepressantsAntihistaminesAntihypertensive A & BAll of the aboveReceptors are usually made up ofLipidsProteinsDNAEstersAminesFactors affecting renal drug secretion ratesCarrier saturationDrug transfer rates across tubular membraneDegree of drug-plasma protein bindingRate of drug delivery to secretory sitesAll of the aboveAbnormalities in blood clotting may be associated with a deficiency of vitaminB12CEB6KIn acute allergic reaction, the first drug that should be administered isPenicillinAdrenalineMorphine sulfateDiclifenac NaAll of the aboveFactors influencing osteoporosis developmentCalcium intakeDegree of physical activitySmokingA & BA & B & CPrimarily used to promote ovulation in patients wishing to become pregnantDanazoleMedroxyprogesteroneClomipheneL-NorgestrelTamoxifenMost common complication of insulin therapy:LipodystrophiesHypotensionGallstonesHypoglycemiaRetinopathySecond generic sulfonylureaChloropromideTolazamideAcetohexamideGlipizideTolbutamideMethylparaben is used in the drug formulation as aDiluentsBuffering agentDisintegrantPreservativeLubricantBeta-receptor antagonist primarily used for the treatment of glaucomaPropranoloEsmololNadololTimololPilocarpineDrugs used to manage allergic reactionsGlucocorticoidsAntihistaminesSubcutaneous epinephrineNone of the aboveAll of the aboveMost current opioid analgesics act at this opioid receptor subtypeSigmaKappaDeltaEpsilonMuMajor adverse effect of heparinOsteoporosisAlopeciaBleedingSpontaneous fracturesReduced glomerular filtrationTo dispense an order calling for:Prednisone 5 mg, one t.i.dx3 days, one b.i.dx3 days , one q.d.x3 daysThe total medication needed is15 tab.18 tab.21 tab.24 tab.27 tab.The drug Adeef contains the following active ingredientCefazolinCefiximeCefdinirCefonicidCefotaximeThe drug Adeef is classified as First generation cephalosporinSecond generation cephalosporinThird generation cephalosporinFourth generation cephalosporinFifth generation cephalosporinMechanism of action for cochicine Direct membrane stabilization Binds to intracellular tubulin-preventing/ reducing microtubule formationDecreases purine synthesis directly Prevents IL-1 release directly None of the aboveA locally manufacture drug that contains the same active ingredient as celebraCelexMovalisBelaraLozarMepralThe active ingredient in Pantover isPanthenolPantoprazoleParoxetineOmeprazoleEsomeprazoleThe manufacturer of Pantover isBirzeitJerusalemPharmacareBeit JalaNone of the aboveThe active ingredient in Effient isPravastatinPraziquantelPremethrinPrasugrelPhenylphrineThe drug Elocom contains the following active ingredientClobetasol propionateMometasonefuroateBuserelinBupropionBudesonThe drug Elocom is manufactured byMSDSchring-PloughNovartisDanpharmBayerA drug that inhibits ADP-induced platelet aggregation is AspirinEptifibatideClopidexTirofibanAbciximabPlavix is manufactured byMSDSchring-PloughNovartisSanofi-aventis BayerThiazides are known to reduce exertion ofDiazepamFluoxetineImipramineLithiumPotasiumThe active ingredient in Amicor drug isAmlodioineIsosorbide mononitrateEnalaprilVerapamilNifedipineThe most likely cause of death associated with an overdose of acetaminophen isArrhythmiaHemorrhage stroke Liver failureNoncardiogenic pulmonary edemaVentilator failureAll of the following belong to macrolides exceptRovamycinErythromycinClarithromycinAzithromycinOfloxacinThe active ingredient in cytotec isCimetidineFamotidineCelecoxibOmeprazoleMisoprostolThe active ingredient in Flucan isFluconazoleItracanazoleDicanazoleMicanazoleBifenazoleA patient allergic to penicillin group antibiotics has to avoideZitrocinKlacidLevoxTaricinDrypenClomiphene citrate is used clinically in the treatment ofPsoriasisDepressionInfertilityDysmenorrhealNauseaLescol 40 mg capsules containsFluvaststin as sodimLevofloxacin hemihydratesAtorvastatinTerbinafine hydrochlorideLoperamide hydrochlorideAll of the following are B antagonists exceptsSalbutamolMetoprololNadololAtenololC & DThe USP content uniformity test for tablets is used to ensure which quality?BioequivalencyDissolutionPotencyPurityToxicity Monitoring of INR is essential in monitoring patients usingHeparinLamotrigineWarfarineGlimepirideAcarbose(81- 90) answer with yes or no:?? ???? ??????? ?? ???? ????? ????? ?? ????? ???????? ???????? ?? ?? ??? ????? ???????? ?? 40 ??? ?????????? ??????? ???? ???? ??????? ??????? ? ?????? ??? ????????? ?????? ?????? ???? 12 ???? ??? ??? ?????? ???? ???? ??? ?????? ? ????? ??? ?? ???? ?????? ???????? ? ?????? ???????? ?? ???? ????? ?????? ?????? ?????? ?????? ?? ?????? ?? ??? ?????? ??????????? ?? ???? ???????? ?????? ??? ???? ??? ???? ????? ????????? ??????????? ??? ????? ?? ???????? ?? ??? ?? ????? ???? ?? ???? ??? ???????? ?????? ??????? ?????? ????? ??? ?????? ????????? ????????? ?????? ?? ??????? ?? ???????? ????? ?????? ????? ???????? ??? ???? ?? ???????????? ????? ???????? ??????? ?? ??????? ?? ??? ?? ??? ???????? ??? ??? ? ?????? ??????? ................
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