National PBM Monograph Template

The incidence of VTE was significantly lower in the fondaparinux group, occurring in 5.6% (18/321) vs. 10.5% (34/323) in the placebo group. Major bleeding occurred in one patient in each group, while minor bleeding was reported more frequently with fondaparinux (2.6% vs. 1%). The use of fondaparinux in this population remains off-label. ................
................