CONTINUING HOMOEOPATHY MEDICAL - LMHI
Inhibitors of this enzyme enhance vascular smooth muscle relaxation and are used for treatment of male impotence. Following is an outline for a synthesis of sildenafil. (a) Propose a mechanism for Step 1. The mechanism for this step involves formation of a hydrazone (Section 16.8) followed by tautomerization to give the fully conjugated system, then another C=N bond forming process. Step 1 ... ................
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