---May 1, 2001 - University of Maryland School of Medicine
Steven M Scharf MD PhD
Curriculum Vitae
8-15-2016
Personal Information
Division of Pulmonary and Critical Care
University of Maryland, Baltimore
100 N Greene Street, 2nd Floor
Baltimore, MD 21201-1192
Phone: 410-706-2010
Fax: 410-706-0345
E-mail: sscharf@medicine.umaryland.edu
Foreign Languages: Hebrew - Fluent
Education
1968 A.B. University of Rochester
1973 M.D. Johns Hopkins
1973 Ph.D. Johns Hopkins University School of Public Health
Ph.D. Thesis- "The influence of coronary flow and vascular pressure on cardiac function and coronary
vascular volume", Thesis advisor Dr. Baruch Bromberger-Barnea, February, 1973.
Post Graduate Education and Training
1970 US Public Health Service Fellowship in Jerusalem,
Laboratory of Environmental Medicine, Prof. H. Shuval,
Supervisor
1973-1974 Medical House Officer, (Medical Internship PGY-1) Peter Bent Brigham Hospital
1974-1975 Assistant Resident Physician, (Medical Residency PGY-2) Peter Bent Brigham Hospital
1975-1976 Research Fellow in Medicine, (PGY-3 First year of pulmonary fellowship) Peter Bent Brigham Hospital
1975-1978 Clinical Fellow in Medicine, Harvard Medical School
1975-1978 Research Fellow in Medicine, Harvard Medical School
1976-1978 Research/Clinical Fellow in Medicine, (PGY-4-5) Peter Bent Brigham
Hospital
1977-1978 Fellow in Pulmonary Diseases, VA Medical Center, West
Roxbury, MA
1978-1979 Junior Associate in Medicine, Peter Bent Brigham Hospital
Certifications
1974 National Board of Medical Examiners – Diplomate; certificate #127549
1977 American Board of Internal Medicine, Internal Medicine Specialty; certificate #56059
1978 American Board of Internal Medicine, Certification in Subspecialty of Pulmonary Diseases; certificate #56059
1980 Scientific Council of Israel, Certification in Specialty of Lung Diseases; certificate #54900
1989-1999 American Board of Internal Medicine, Certification in Critical Care; certificate #56059
2000 American Board of Sleep Medicine - Certification in Sleep Medicine (Diplomate); certificate #1482
Medical Licensures
1980- State of Israel #54900
1988 - New York State #175385 (inactive status since 2002)
2002 - State of Maryland #D0058344
Employment History
Academic Appointments
1978–1979 Instructor in Medicine Harvard Medical School, Boston, MA
1978-1980 Research Associate, VA Medical Center, West Roxbury, MA
1978-1980 Junior Associate in Medicine, Peter Bent Brigham Hospital,
Boston, MA
1979. Assistant Professor of Medicine, Harvard Medical School, Boston, MA
1980-1984 Senior Lecturer in Medicine, Ben-Gurion University of the
Negev, Faculty of Health Sciences, Beersheba, Israel
1986 Visiting Professor University of Toronto School of Medicine
1984-1988 Assistant Professor of Medicine, Harvard Medical School, Boston, MA
1989-1995 Associate Professor of Medicine, Albert Einstein College of Medicine, Bronx, NY
1992 Visiting Professor, University of Toronto School of Medicine
1994 Visiting Professor, Ben-Gurion University of the Negev,
Beersheba, Israel
1996 - 2002 Professor of Medicine, Albert Einstein College of Medicine
1996 Dozor Visiting Professorship, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev (1 month honorary visiting professorship)
1997 Adjunct Professor of Medicine, Columbia University
2002- Professor of Medicine with tenure – University of Maryland, School of Medicine
2008- Visiting Professor of International Medicine, Ben-Gurion University of the Negev
Professional Society Memberships
Examiner, Israel Medical Association Scientific Council,
Pulmonary Diseases Specialty Certification 1982 –1984
Member, Board of Directors, Israel Society for Clinical Investigation 1982 - 1984
American Thoracic Society 1978 -
American Physiological Society 1978 -
Israel Society of Chest Physicians 1980 - 1984
Israel Society for Physiology and Pharmacology 1982 - 1984
Israel Society for Clinical Investigation 1980 - 1984
American Heart Association- Cardiopulmonary Council 1984 -
American Association for the Advancement of Science 1988 -
Society for Critical Care Medicine 1988 -
American Academy of Sleep medicine – Fellow 1999 -
New York Society of Sleep Medicine 1999 -
Honors and Awards
1968 Phi Beta Kappa University of Rochester
1972 Alpha Omega Alpha Johns Hopkins Medical School
1978 Recipient of V.A. Career Development Award Veterans Administration
Clinical Activities
1978 -1980 Staff Physician, VA Medical Center, West Roxbury, MA
1979 -1980 Attending Physician, Pulmonary Section, West Roxbury, VA Medical Center
1980 -1984 Director, Division of Lung Diseases, Soroka Medical Center, Beersheba, Israel
1984 -1988 Attending Physician, Medical Service, West Roxbury VA Medical Center
1984 -1988 Attending Physician, Pulmonary Section, West Roxbury, VA Medical Center
1988 - 2002 Attending Physician, Division of Pulmonary and Critical Care Medicine; LIJMC
1989 - 2002 Section Head, Adult Pulmonary Research, Long Island Jewish Medical Center
1994. - 2002 Full Attending Physician, Long Island Jewish Medical Center
2002 - Director, Sleep Disorders Center, University of Maryland
2002 - Attending Physician, Pulmonary and Critical Care Division, University of Maryland
Administrative Service
Institutional Service
1979-1980 Research and Development Committee, VA Medical Center, West Roxbury, MA
1980-1984 Director, Division of Lung Diseases, Soroka Medical Center, Beersheba, Isreal
1981-1983 Animal House Committee, Ben-Gurion University of the Negev, Beersheba, Israel
1984-1985 Intensive Care Committee, VA Medical Center, West Roxbury, MA
1987-1988 Chairman, Research and Development Committee, VA Medical Center, West Roxbury, MA
2002. Research Committee, Long Island Jewish Medical Center
1989-2002 Section Head, Pulmonary and Critical Care Research Long Island Jewish Medical Center
1990-1993 Member - Pharmacy and Therapeutics Committee, Long Island Jewish Medical Center
1993-2002 Chairman Pharmacy and Therapeutics Committee, Long Island Jewish Medical Center
1996 -1999 Chairman, Research Committee, Long Island Jewish Medical Center
1997 -1999 Member, Professorial Promotion Committee, Albert Einstein College of Medicine
1998- 2002 Associate Chairman of Medicine for Academic Affairs, Long Island Jewish Medical Center
2000 -2002 Member Coordinating Committee, Dept of Medicine, Albert Einstein College of
Medicine
2002- Director, Sleep Disorders Center, University of Maryland
Local and National Service
1988-1990 Cardiopulmonary Council American Heart Association: Executive Committee
1995. Member of NIH Workshop on Lung Volume Reduction Surgery
1996- 2002 Member of Steering Committee, Clinical Trial of Lung Volume Reduction
Surgery, NHLBI
1999 - 2002 Member of Steering Committee, Feasibility studies on retinoid treatment in
emphysema (FORTE), NHLBI
1998 - 2002 Member of steering committee for Asthma Clinical Research Center
Network of American Lung Association
2002 - 2005 Member, Health Care Policy Committee of the American Academy of Sleep
Medicine
2003 Member, Research Committee, Maryland Lung Association
2003 - Member, Steering Committee, COPD Clinical Research Network, NHLBI
2005. Study Section, Rehabilitation, VA Merit Review
2005 - 2006 Member, Respiratory Neurobiology and Sleep assembly of the ATS Programming Committee
2005 - 2006 Member, Committee for polysomnographic technology standards, Am Academy of Sleep Medicine
2005 Session moderator: Sleep apnea from vessels to pump. Spring meeting of American Thoracic Society
2005 - 2007 Member, Program Planning Committee, Maryland Thoracic Society
2007 - Member, Steering Committee, Long-Term Oxygen Treatment Trial, NHLBI
2008 Member: Special Review Committee; NHLBI: SPIROMICS trial
2008 Session moderator, minisymposium at ATS meeting (May 2008): Lung Volume Reduction Surgery
2008 Session moderator, poster discussion session ATS meeting (May 2008): Animal models of intermittent hypoxia and sleep apnea.
2008 Member Special Review Committee for SPIROMICS trial, National Institutes of Health
2010 - Medical Director sleep technologists training program, Community College of Baltimore County.
Teaching Service
1984. Respiratory Physiology and Medicine, Third Year Course in the Medical School, Course organizer: Faculty of Health Sciences, Ben-Gurion University, Beersheba, Israel
A 6 week systems related course on the respiratory system: Included histology, anatomy, pathophysiology and clinical medicine for both adult and pediatric respiratory diseases and critical care medicine. I was course organizer, wrote the syllabus, and spent approximately 36 hours teaching over the 6 weeks (the amount per day varied). My direct teaching responsibilities included all of the basic physiology teaching, both didactic as well as in the form of lecture – demonstrations. I also participated in the teaching of the pathophysiology of certain respiratory diseases, e.g. COPD, asthma, and some of the clinical teaching – including lung cancer and infections. There were 45 – 50 students enrolled each year. I also supervised groups of students (5 – 8) per group for 2 hours per day, total of 3 days, for teaching rounds on respiratory patients. In addition to teaching, my duties included arranging the teaching schedule, reviewing student evaluations of the course and individual instructors, and organizing and grading the final exam. Feedback was provided to the Dean’s office and conferences were held with the instructors. I organized the administration of the final exam and make up exams. I also was responsible for counseling students during the course and providing feedback between students and faculty.
1984. Respiratory Physiology, First Year Course in the Medical School, Faculty of Health Sciences, Ben-Gurion University, Beersheba, Israel
My responsibilities included teaching most of the basic respiratory and some of the cardiovascular physiology to Year I students. These were geared more to general mammalian physiology rather than clinical medicine. I taught approximately 10 hours over a 5 week period. Teaching was primarily didactic. However, I also conducted groups of 4 – 5 students on clinical rounds that were meant to serve as an introduction to the clinic. Each year I spent approximately 6 hours (2 sessions with 2 groups of students).
1984. Advanced Cardiopulmonary Physiology to senior and graduate students in the Department of Biology, Ben-Gurion University, Beersheba, Israel
This was a course taught in the graduate school, and was listed in the graduate school. It was open to undergraduate seniors and graduate students. I was the course instructor and organizer. Teaching consisted of twice weekly sessions of 2 hours each for a semester. Teaching was in the form of lectures (half the sessions) and lecture demonstrations (in the physiology laboratory). There were 8 – 10 students in the course. In addition to teaching all the sessions, I created the syllabus, wrote and graded the final exam. I also supervised 2 graduate students who assisted with the lecture – demonstrations.
1991 - 1994 Advanced cardiopulmonary physiology to pulmonary and cardiology fellows: Course organizer, Long Island Jewish Medical Center
This course is taught every other summer for 10 weeks, one hour per week and is mandatory for fellows in the Pulmonary and Critical Division and open to Cardiology Fellows. Total enrollment approximately 10. The focus of the course is to review advanced principles in Cardiopulmonary physiology as they relate to clinical medicine and the treatment of critically ill patients. The material is based on my second book (Cardiopulmonary Physiology for Critical Care) and covered such diverse areas as: cardiac muscle contraction, concepts of pressure/flow and pressure volume relations, control of venous return and cardiac output, determination of maximum airflow, pulmonary mechanics, respiratory muscle function, and cardiopulmonary interactions.
1992- 1996 Yearly lectures in pulmonary pathophysiology, City University of New York
This was one lecture per year on pulmonary hypertension to second year students at the City University of New York Medical School. Number of students: 25
1993- 1997 Respiratory Physiology to MD PhD Students: course organizer: Albert Einstein College of Medicine
As part of the MD PhD program, in the first year students were given a physiology course over the first year. The respiratory section was 4 hours per week over 8 weeks (one day per week in the Spring). I was course organizer, was responsible for organizing the syllabus and final exam as well as grading the final exam. I was also responsible for feedback between the instructors and students. I personally taught half the sessions (total 16 hours). Our mission was to avoid the typical didactic basic physiology lecture and to focus on review of landmark papers in the field as a teaching tool. This was extremely challenging and necessitated a fair amount of adaptation on the part of both the instructors and the students.
1994 - 2002 Scientific Basis of research and practice of medical subspecialties - given to all clinical and research fellows in the Department of Internal Medicine: course organizer; Long Island Jewish Medical Center
This course was given within the framework of the Department of Medicine and is mandatory for all fellows for all divisions within the department. The course is given every other year for a semester, once per week for one hour per week. I am the originator and organizer of the course. I am responsible for developing the syllabus, obtaining instructors, and obtaining feedback from fellows and instructors. I personally teach 4 – 5 of the lectures. The premise of the course was that all subspecialty boards require didactic instruction in the scientific basis of advanced medical practice for certification. Review of the requirements revealed certain common trends, which formed the basis of the syllabus. Material covered includes: Introduction to research methodology, basic statistics, principles of clinical trials, molecular biologic basis of disease, cellular biology and disease, meta-analysis, signal
processing, immunology – principles and testing, and ethics and regulatory principles of medical research. Number of fellows: 16 – 20.
1988 - 2002 Instructor in Board Review Course to Medical Residents
Total of 2 – 4 hours of didactic lectures on respiratory topics - part of the board review course given to medical residents at Long Island Jewish Medical Center. I taught between 2 to 4 lectures each year. Topics included: pulmonary function testing, pulmonary hypertension, pulmonary thromboembolism, COPD. Each lecture was 1 hour long – requiring approximately 1 hour preparation time.
2000 - Respiratory Physiology/Pathophysiolgy (second year): Medical School for International Health, Ben-Gurion University, Beersheba, Israel, under the auspices of Columbia University, New York
This course is organized as part of the International MD Program at the Ben-Gurion University of the Negev in Israel. This program, developed in cooperation with Columbia University consists of an American style medical curriculum, taught in English to students from around the world. The respiratory section of the course is, interestingly, based on the original respiratory course I organized in 1980 for the Israeli program at BGU. I travel each year to Israel as guest lecturer to the Faculty of Health Sciences at BGU. I teach all of the respiratory physiology and a fair amount of the pathophysiology to second year students in the program. Over the 3 weeks I spend each year I spend approximately 30 hours in the classroom giving didactic lectures to the students. I also run a review session (ask me anything) in respiratory physiology and pathophysiology towards the end of the course (2 – 3 hours). I am responsible for writing the exam questions in respiratory physiology and much of pathophysiology. Number of students 40 - 50. I also round on the internal medicine service with students in year III on the internal medicine wards.
2002 - 2006 Member course coordinating committee: Pathophysiology and Therapeutics course for second year medical students, University of Maryland School of Medicine. Duties included curriculum planning for the entire course, as well as recruitment of instructors in the pulmonary topics (major lectures and small groups), and organizing the teaching cases for the pulmonary small groups sessions (see below). I also review the individual instructor evaluations for the pulmonary section of the course.
2003 - 2006 Instruction to 2nd year students in Pathophysiology and Therapeutics course – Small group organizer for COPD and asthma, lecture in sleep disordered breathing.
I organized the small group sessions on COPD and asthma in the 2nd year P&T course. As part of the reorganization of this part of the course, I introduced taped patient interviews for the asthma and COPD sections, which were coordinated with clinical, pathological and physiological data in the context of the small group sessions. The students gave excellent ratings to this. I was a small group instructor (15 – 20 students per group) for both the asthma and COPD small group sessions. I have been pushing for inclusion of more sleep-related lectures in the context of this and other courses. I have been informed that for the coming SY an additional hour will be given for understanding the role of sleep disturbances and sleep disorders in respiratory and other disease processes. I will be teaching this additional teaching hour.
2003 - Instruction to 2nd year students in Pathophysiology and Therapeutics Course – I lecture to the second year students on sleep apnea and sleep disturbances, and I am an instructor for small groups sessions in sleep apnea, asthma, COPD, and pulmonary function testing.
2002 - Clinical teaching responsibilities at University of Maryland.
I attend at the VA on the ICU/pulmonary consult service 1.5 months per year. I round with the medical house staff each morning for 2 – 3 hours in the ICU on this service. I try to incorporate teaching minilectures (20 – 30 minutes long) 2 – 3 morning per week. I also supervise the pulmonary fellow on rotation in consults and bronchoscopies.
I run the University of Maryland sleep clinic two mornings per week. There are always at least two fellows at each session. Residents also may elect to participate in this clinic from neurology, psychiatry, pulmonary and internal medicine for one month rotations. I supervise the residents and fellows in evaluation and management of sleep disorders.
Once a week, there is a teaching session on interpretation of sleep studies. This is attended by the sleep fellows and residents on rotation on rotation in the sleep service. Additionally, there is a teaching conference for the sleep medicine and pulmonary fellows called the “multidisciplinary” conference.
2003 - 2006 Lecturer and course co-organizer for Pulmonary Fellows for core curriculum: Cardiopulmonary physiology. The course was supplanted by an all-year lecture series in basic pulmonary biology, which I organized (see below).
This was part of the core curriculum given to pulmonary fellows. I organized the physiology part of the course. There were a total of 8 weekly 1-hour lectures for this part of the course. I delivered 5 of these. Preparation time for each is approximately 1 hour. Number of fellows/residents: 10.
2003 - 2006 Lecturer in basic research course for fellows in Dept. of Medicine: 2 lecturers given on 1) Research Methods; 2) The role of the Physician-Scientist. Each lecture lasted 1 hour.
This is a 2-week course on basic research techniques offered to fellows in the Dept. of Medicine who are engaged in laboratory research. The syllabus is available at . Number of fellows: 20
2004 - 2008 Course organizer: CME course; New Horizons in Sleep. This is a course given at the Univ of Maryland, University Specialty Hospital to focus on newer findings and viewpoints in sleep medicine. Number of attendees: approximately 35.
2005 - 2008 Pulmonary Biology: Weekly noontime course in basic pulmonary physiology. Course organizer and gives all of the physiology lectures. This is a course covering basic pulmonary biology including physiology, inflammation, molecular biology, and principles of physiological measurement, altitude and diving physiology, sleep, statistics and other such diverse topics. This course goes over a 2 year period. Number of fellows: 12.
2006 - Core Course in Sleep Medicine (“Sleep Boot camp”). Multidisciplinary course in sleep medicine. Participate in Organizing the course and deliver 4 of the lectures. Given to Fellows/residents/attendings in Pulmonary, Neurology, Pediatrics, ENT and others interested.
2007 - 2009 Course organizer of Respiratory System Section of Functional Systems (Physiology) Course to the first year medical students. Teaches half the lectures, organizes small groups sessions.
2007 PhD Thesis Committee: Derya Coursey, University of Maryland, College Park
2008 PhD Thesis Committee. Sonia Garcia, Capella University, CA.
2008 - 2012 Fellowship director: Sleep Medicine, an RRC approved fellowship in sleep medicine.
2010 - Participate in Small Groups Sessions in Respiratory System section of Functional Systems.
2010 - Lectures on Sleep Apnea in second year pathophysiology and therapeutics course.
Community/Other
2010, 2012, 2014 Named as one of Baltimore’s “Top Docs”
Guest Editor, Israel Journal of Medical Sciences Series on Basic Science and Application to Pulmonary Diseases 1982-1983
Editorial Board:
Journal of Critical Care 1988 – 1999
Sleep and Breathing 2005 - 2010
Journal Reviewer:
Acta Phys Scan
American J Resp Crit Care Med
Chest
Circulation
Circulation Research
Eur J Respiration
Eur Resp Journal
In J Obesity
Intensive Care Medicine
Israel Journal of Medical Sciences
J Auton Pharmacology
Journal of Applied Physiology
New England Journal of Medicine
Nutrition, Metabolism & Cardiovascular Disease
Pflugers Archiv
Sleep
Sleep and Breathing
Journal of COPD
Int J COPD
J Clin Sleep Med
S Scharf Supervision/sponsorships
84. PhD supervisor for Hilton Bark, DVM, Soroka Medical Center, Beersheba, Israel. "Effects of Diaphragm Fatigue on Blood Flow and Neural Transmission in the Canine Diaphragm." Current position: director animal hospital Rehovot, Israel, Professor of Veterinary Medicine on faculty at Hebrew University School of Veterinary Medicine.
84. Masters thesis supervision: Ariel Tarasiuk, Soroka Medical Center, Beersheba, Israel. "Respiratory respiratory muscle conditioning with chronic tracheal obstruction." Current Position: Professor of Medicine and Physiology, Ben-Gurion University of the Negev, Director of the Laboratory for Sleep Disturbances, Soroka Medical Center, Beersheba, Israel.
1991-93 Sponsor for Fogarty International Fellowship recipient,
Ariel Tarasiuk, Ph.D. " Effects of PEEP on Left Ventricular
Function and Metabolism.” See above for current position.
1993. I Salejee MD, Medical Resident. “Chronic upper airways obstruction produces right but not left ventricular hypertrophy in rats.” Current position: private practice.
1993. Nicole Kane, University of Rochester: “Effect of naloxone on long-term suppression of ventilatory control in rats.” Current position: unknown
1994. Michael Kupferman, Yeshiva University: “Nutritional and metabolic sequelae of chronic airway obstruction in rats”. Honors course for Dept of Biology, Yeshiva University. Current position: Associate Professor Head and Neck Surgery at The University of Texas, MD Anderson Hospital in Houston, Tx.
1995. J. Genovese MD, Pulmonary Fellow. “Effects of CPAP on cardiac output in normal hearts and congestive heart failure.” Currently in private practice.
1994 Udey Patel, Albert Einstein College of Medicine: “Mechanisms of cardiac effects of CPAP.” Current position unknown.
1994 RS Rao MD, Medical Resident. “Mechanisms of myocardial depression following bolus injection of sodium bicarbonate.” Current position: private practice.
96. S. Huberfeld MD, Pulmonary Fellow. “Effects of CPAP on respiratory mechanics and cardiac energetics.” Current position: private practice, Director Private Sleep Disorders Laboratory.
1996-98 Rubin I Cohen MD, Pulmonary Fellow: “Nitric Oxide Inhibition and Sepsis”. Current position: Associate Professor of medicine: Albert Einstein College of Medicine.
97. Ling Chen MD PhD. Post-doctoral studies: "Cardiovascular effects of apneas." International Fellow from Shanghai, PR China. Current Position: Assistant Professor of Medicine and Physiology, University of Maryland School of Medicine, director: Core Laboratory for Physiologic Genomics and Small Animal Physiology.
1997- 98 Ifediora F. Afulukwe, MD, Pulmonary Fellow: Mentor on Small grants program: “Role of Nitric Oxide as a myocardial depressant in endotoxemia.” Current position: private practice.
1998. Ayo Harris-Eze MD, Medical Resident, Mentor on resident research project: “Analysis of lack of agreement between FEV1 and PEFR in acute asthma.” Current position: unknown
1998 - 1999 Brian Benoff MD, Pulmonary Fellow: “Role of NO in blood pressure regulation with chronic intermittent hypoxia in rats.” Current position: private practice.
1998 - 2000 Maung Oo MD, Pulmonary Fellow: “Pulmonary hemodynamic changes with apneas in sedated pigs.” Current position: private practice.
1999 - 2001 Kamel Marzouk MD, Pulmonary research fellow: “Correlates of resting O2 consumption in severe emphysema.” Current position: private practice.
1999 - 2002 Mobeen Iqbal MD, Pulmonary Fellow: “Hemodynamic effects of severe emphysema.” Currently on the faculty of a teaching hospital in Pakistan.
1999-2001 Archana Mishra MD, Pulmonary Fellow: “Demographics of asthma in hospitalized patients”. Current position: unknown.
2003 Talia Landau: summer research intern: “Determinants of treatment modalities for obstructive sleep apnea.” Current position: Resident in family medicine, UCLA.
2003 - Heidi Abdelhady MD, Pulmonary Fellow, U of MD. “Infliximab in the treatment of COPD – a pilot study.” Current Position: private practice.
2003 Jennifer DeMore MD, Medical Resident, U of MD. “Comparison of primary care practitioners and sleep specialists in the treatment of obstructive sleep apnea.” Current position: unknown
2004 Abby Tubman: summer research intern: “Concomitant sleep disorders in sleep apnea.” Current position: medical student Howard University School of Medicine.
2005-6 Kevin Welch: ENT resident. “Context validity of HUI 2/3 in sleep disorders.” Current Position: unknown.
2005-6 Henry Tan: Pulmonary Fellow. “Error analysis in office spirometry.” Current Position: private practice.
2006 - Antoinette Williams MD: NIH fellow (completing studies at University of MD). “Oxidative stress in a rodent model of sleep apnea.” Current position: Assistant Professor of Medicine, University of South Carolina School of Medicine.
2006-2010 Janet Lam MD: Faculty, Dept of Pediatric Neurology. “Effects of sleep deprivation on neurocognitive function in children.” K-12 award. Current Position: Assistant Professor of Neurology, Johns Hopkins University School of Medicine, Kennedy Krieger Institute.
2006-2011 Jeanne Geiger-Brown, PhD, RN : Faculty, School of Nursing, “Sleep, sleepiness and neurocognition in 12 hour nurses.” K-12 award. Current position: Associate Professor of Nursing, University of Maryland School of Nursing.
2008-2009 Kathleen Sarmiento MD MPH: “Pulmonary Hypertension in Sleep Apnea”. Current position: Assistant Professor of Medicine, UCSD, California
2011-2012 Daniel King MD: “Nutritional aspects of COPD.” Current position: Lecturer in Medicine, Technion, Haifa, Israel
2013 - 2015 Robert Reed MD: “COPD in the Amish.” FAMRI. Current Position: Asst. Prof of Medicine, Univ of Maryland, Baltimore, MD.
2013 - 2014 Faculty Advisor, Capstone Project, University of Maryland, Dept. of Biomedical Engineering, College Park, MD. Project “Wireless Continuous Core Temperature Sensor for the Precise Tracking of Circadian Rhythm.”
2014 - Brian Johnson, PhD candidate in School of Occupational Therapy. Project: Memory reactivation during sleep to improve motor learning On adviser committee and mentor.
Note: publications from these mentees are listed in a separate document.
Teaching Award
2002, 2004 Outstanding Teacher in Oncology-Pulmonary-Epidemiology; Pathophysiology and Therapeutics Course
Grant Support
Current Funding
2008 - Various pharmaceutical funding (see list)
Past Support
1975 – 1977 American Thoracic Society Fellowship Grant: Cardiovascular effects of Positive End-Expiratory Pressure. Role on project: Principal investigator. Salary Support, Direct Costs $70,000.
1978 - 1980 Veterans Administration Career Development Award. Role on project: Principal investigator. Direct Costs $130,000.
1981 - 1983 Ministry of Health, Office of the Chief Scientist (Israel):“Mechanisms of Respiratory Muscle Fatigue.” Role on project: Principal investigator. Direct Costs: $35,000.
1983 - 1985 Ministry of Health, Office of the Chief Scientist (Israel): “Changes in Oxygen Supply to the Diaphragm with Normal and Abnormal Ventilation.” Role on project: Principal investigator. Direct Costs: $35,000.
1987 - 1988 Harvard Medical School, Proctor Fund: “Screening for Sleep Apnea Syndrome.” Direct Costs: $8,000. Role on project: Principal investigator.
1988 - 1990 Stony-Wold-Herbert Fund: “Effects of Respiratory Maneuvers of Global LV Function and Metabolism.” Role on project: Principal investigator. Direct Costs: $20,500.
1988 – 1990 Long Island Jewish Medical Center Competitive Pool Grant-in-Aid Funding: “Effects of Inspiratory Loading on Regional LV Function and Ischemia.” Role on project: Principal investigator. Direct Costs: $58,000.
1988-1989 Long Island Jewish Medical Center Competitive Pool Shared Instrumentation award: “Effects of Inspiratory Loading on Regional LV Function and Ischemia.” Role on project: Principal investigator. Direct Costs: $50,000.
1992 - 1994 American Heart Association, N.Y. State Affiliate: “Effects of CPAP on Cardiac Function.” Role on project: Principal investigator. Direct Costs: $58,000.
1994 - 1995 Long Island Jewish Medical Center Competitive Pool Funding: “Effects of Intrauterine Cocaine Administration on Ventilatory Control in Rats.” Role on project: Principal investigator. Direct Costs: $34,000.
1994 - 1997 National Institute of Health: “Cardiovascular Effects of Apneas and CPAP.” RO1 HL49808. Role on project: Principal investigator. Direct Costs: $316,891.
1998 - 2002 American Lung Association, Asthma Clinical Research Center: First Study: Safety of Inactivated Influenza Vaccine in Asthma. Role on project: Principal investigator. Direct Costs Awarded for Period: $745,430.
1992 - 1993 N.Y. Lung Association: “Mechanisms of Decreased Hypercapnic Ventilatory Control in Chronic Upper Airway Obstruction in Rats. Role on project: Investigator. P.I. Harly Greenberg, M.D. Direct Costs: $40,000.
1996 - 1998 American Lung Association: “Role of NO Synthase Inhibitors in Treatment of Endotoxic Shock.” Role on project: Investigator. Principal Investigator Rubin Cohen, M.D. Direct Costs: $40,000.
2000. National Institutes of Health: Multisite Study on the Effects of CPAP on Quality of Life in Sleep Apnea. Role on project: Investigator. Principal Investigator Terri Weaver, PhD (University of Pennsylvania). Because payment was capitated, income cannot be split into Direct and Indirect Costs. Approximate income was $40,000 at the LIJMC study site.
1996 - 2003 National Institute of Health: “Clinical Trial of Lung Volume Reduction Surgery.” RFP HR 97-02. Clinical Site (NETT). Joint contract, Columbia University – LIJMC. Role on project: Co-Principal investigator of Long Island Jewish – Columbia site. Currently continuing here at U Maryland as investigator; Principal Investigator Mark Ginsberg, M.D. Total Costs Awarded: $1,750,544. Current Annual Cost: $289,124.
1999 - 2003 National Institute of Health: Clinical Centers for Feasibility Studies on Retinoid Treatment in Emphysema (FORTE). RFP NHLBI HR 99 01. Joint contract Columbia University. Role on Project: Co-Principal investigator of LIJMC-Columbia study site. At U Maryland continuing on as investigator and member of the steering committee. Principal Investigator Neil Schluger, M.D. Direct: $1,588,501, Indirect Costs: $370,975. Total costs awarded: $1,959,476, Current Annual Cost: $851,679
2003 – 2004 Maryland Tobacco Restitution fund: Infliximab treatment in COPD. Role on project: Principal investigator. Direct costs: $75,000. No indirect costs.
2003 – 2004 American Lung Association: Effects of Chronic Intermittent Hypoxia on oxidative stress and proinflammatory cytokines in rats. Role on project: Principal Investigator. Direct costs: $10,000, Indirect Costs: NA
2002 - 2006: Cardiovascular Stress of Sleep Apnea and Heart Failure. HL071506 (Schwartz) Role on Project: Co-investigator. Direct Costs: $250,000
2003 – 2008: National Institutes of Health: Evaluation of Home Asthma Telemanagement in COPD. R01 HL071690. Role on Project: Co-investigator. Direct Costs: $425,958
2006-2008: American Heart Association: Oxidative Stress and Myocardial Function in a rodent model of sleep apnea. AHA 0655487U. Role on project: PI. Direct Costs: $120,000. Indirect costs: $12000.
2003 – 2011 National Institutes of Health: Clinical Center – COPD Clinical Research Network. HL074441, Role on project: Principal investigator. Direct Costs: $3,000,000, Indirect Costs: $957,875. Total Costs: $3,957,875
2007 - 2015 National Institutes of Health: Long-term oxygen treatment trial. HR76190; Role on project: Co-PI of the Mid-Atlantic LOTT consortium (Criner, Temple PI). Capitation
Publications - Journal (Refereed)
1. Scharf SM, Bromberger-Barnea B, Permutt S. Distribution of coronary venous flow. J Appl Physiol. 1971; 30:657-662. PMID: 5572788
2. Scharf SM, Bromberger-Barnea B. Influence of coronary flow and pressure on cardiac function and coronary vascular volume. Am J Physiol. 1973; 224:918-925. PMID: 4698809
1. Scharf SM, Thames M, Sargeant RK. Transmural myocardial infarction after exposure to carbon monoxide in coronary artery disease. N Eng J Med. 1974; 85-86. PMID: 4835888
2. Scharf SM, Permutt S, Bromberger-Barnea B. Effects of hypoxic and CO induced hypoxia on isolated hearts. J Appl Physiol. 1975; 39:752-758. PMID: 1184514
3. Scharf SM, Caldini P, Ingram RH. Cardiovascular effects of increasing airway pressure in dogs. Am J Physiol. 1977; 232:H35-H43. PMID: 319686
4. Scharf SM, Ingram RH. The effects of decreasing lung compliance on the cardiovascular response to PEEP. Am J Physiol. 1977; 233:H635-H641. PMID: 339748
5. Scharf SM, Ingram RH. Influence of abdominal pressure and sympathetic vasoconstriction on the cardiovascular response to PEEP. Am Rev Resp Dis. 1977; 116:661-670. PMID: 335933
6. Scharf SM, Feldman NT, Goldman M, Haut NA, Bruce E, Ingram RH. Vocal cord closure: A cause of upper airway obstruction during controlled vs assisted ventilation. Am Rev Resp Dis. 1978; 117:391-397. PMID: 273387
7. Scharf SM, Feldman NT, Grayboys T, Wellman JJ. Restrictive ventilatory defect in a patient with primary pulmonary hypertension. Am Rev Resp Dis. 1978; 118:409-413. PMID: 697189
8. Sylvester J, Scharf SM, Gilbert R, Fitzgerald R, Traystman R. Hypoxic and CO hypoxia in dogs: Hemodynamics, carotid reflexes and catecholamines. Am J Physiol. 1979; 236:H22-H28. PMID: 434170
9. Scharf SM, Brown R, Saunders N, Green LH. Changes in canine left ventricular size and configuration with positive end-expiratory pressure. Circ Res. 1979; 44:672-678. PMID: 371854
10. Scharf SM, Brown R, Tow DE, Parisi AF. Cardiac effects of increased lung volume and decreased pleural pressure in man. J Appl Physiol. 1979; 47:257-262. PMID: 468681
11. Scharf SM, Brown R, Saunders NA, Green LH. Effects of normal and loaded spontaneous inspiration on cardiovascular function. J Appl Physiol. 1979; 47:582-590. PMID: 533753
12. Scharf SM, Feldman NT. Pulmonary Cryptococcosus in and immuno- suppressed host. Clin Notes in Resp Dis. 1979; 18:12-13. PMID: 535192
13. Slutsky AS, Scharf SM, Brown R, Ingram RH. The effect of oleic acid induced pulmonary edema on lung and chest wall mechanics in dogs. Am Rev Resp Dis. 1980; 121:91-96. PMID: 7352717
14. Scharf SM, Brown R, Saunders NA, Green LH. Hemodynamic effects of positive pressure inflation. J Appl Physiol. 1980; 49:124-131. PMID: 6995414
15. Strohl KP, Hensley MJ, Saunders NA, Scharf SM, Brown R, Ingram RH. Progesterone administration and progressive sleep apneas. JAMA 1981; 245:1230-1232. PMID: 6451714
16. Brown R, Scharf SM, Ingram RH. Non-homogeneous alveolar pressure swings in the presence of airway closure. J Appl Physiol. 1980; 49:398 – 402. PMID: 6461622
17. Scharf SM, Bianco JA, Tow DE, Brown R. The effects of large negative intrathoracic pressure on left ventricular function in patients with coronary artery disease. Circulation 1981; 63:871-875. PMID: 7471344
18. Scharf SM, Heimer D, Goldstein J. Pathological and physiological effects of aspiration on hydrocarbons in the rat. Am Rev Resp Dis. 1981; 124:625-629. PMID: 7305118
19. Urmey WF, Scharf SM, Brown R, Carlson D, Song P. Effect of interstitial fluid (kerosene) on pressure volume characteristics of rat lung. J Appl Physiol. 1982; 52:260-266. PMID: 7061272
20. Scharf SM, Brown R. The influence of the right ventricle on canine left ventricular function with positive end-expiratory pressure (PEEP). J Appl Physiol. 1982; 52:254-259. PMID: 7037711
21. Brown R, Scharf SM, Ingram RH. Non-homogeneous alveolar pressure swings: Effect of different respiratory muscles. J Appl Physiol. 1982; 52:638-641.
22. Scharf SM, Prinsloo I. Pulmonary mechanics in dogs given different doses of intratracheal kerosene. Am Rev Resp Dis. 1982; 126:695-700. PMID: 7125363
23. Heimer D, Scharf SM, Lierberman A, Lavie P. Sleep apnea syndrome treated by repair of deviated nasal septum. Chest 1983; 84:184-185. PMID: 6872599
24. Scharf SM, Gardsbane A. Chest wall movements during inspiratory loading in dogs. Respiration 1984; 45:26-34. PMID: 6227963
25. Scharf SM, Bark H, Heimer D, Cohen A, Macklem PT. Second wind during inspiratory loading. Medicine and Science in Sports and Exercise. 1984; 26:87-93. PMID: 6708787
26. Scharf SM, Bark H. Function of the canine diaphragm with hypovolemic shock and beta adrenergic blockade. J Appl Physiol. 1984; 56:648-655. PMID: 6142877
27. Scharf SM, Bye P, Pardy R, Macklem PT. Dyspnea, fatigue, and second wind. Am Rev Resp Dis. 1984; 129:88-89.
28. Tal A, Aviram M, Bar-Ziv J, Scharf SM. Residual small airways lesion after kerosene pneumonitis in early childhood. Eu J Ped. 1984: 142:117-120. PMID: 6468426
29. Sofer S, Bar-Ziv J, Scharf SM. Pulmonary edema following relief of upper airway obstruction. Chest 1984; 86:401-403. PMID: 6432456
30. Heimer D, Bar-Ziv J, Scharf SM. Fiberoptic bronchoscopy in patients with hemoptysis and non-localizing chest x-ray. Arch Int Med. 1985; 145:1427-1428. PMID: 4026474
31. Scharf SM, Heimer D, Walters M. Bronchial challenge with room temperature isocapnic hyperventilation: Comparison with histamine challenge. Chest 1985; 88:586-593. PMID: 3930161
32. Scharf SM, Bark H, Einhorn S, Tarasiuk A. Blood flow to the canine diaphragm during hemorrhagic shock. Am Rev Resp Dis. 1986; 133:205-211. PMID: 3946919
33. Bark H, Scharf SM. Diaphragmatic blood flow in the dog. J Appl Physiol. 1986; 60:554-561. PMID: 3949660
34. Bark H, Scharf SM. Effect of phrenic nerve stimulation on neural transmission and diaphragmatic force generation in the dog. Resp Physiol. 1986; 63:1-13. PMID: 3008285
35. Scharf SM, Warner KG, Josa M, Khuri SF, Brown R. Load tolerance of the right ventricle: Effect of increased aortic pressure. J Crit Care. 1986; 1:163-173.
36. Goldsmith JR, Scharf SM, Israeli R. Pulmonary function screening and monitoring in occupational health. J Occ Med 1986; 28:656-663. PMID: 3746487
37. Strohl KP, Scharf SM, Brown R, Ingram RH. Cardiovascular performance during bronchospasm in dogs. Respiration 1987; 51:39-48. PMID: 3563122
38. McIntyre KM, Parisi AF, Brown R, Tow DE, Folland ED, Sharma GVRK, Scharf SM, Pietro D. Validation and application of a non-invasive Valsalva response recorder. J Appl Cardiol 1987; 2:137-169.
39. Scharf SM, O'B Woods B, Brown R, Parisi AF, Tow DE, Miller MM, McIntyre K. Mueller Maneuver and LV function in coronary artery disease. Ann Biomed Engin 1987; 15:297-310. PMID: 3662148
40. Scharf SM, O'Beirne Woods B, Brown R, Parisi AF, Miller MM, Tow DE. Effects of Mueller maneuver on global and regional left ventricular function in angina pectoris with or without previous myocardial infarction. Am J Cardiol 1987; 59:1305-1309. PMID: 3591684
41. Sobel R, Zabelle S, Scharf SM. Increased prevalence of strongly positive tuberculin skin reactions in children from a desert agricultural community in Israel. Ped Infect Dis 1987; 6:766-768. PMID: 3670942
42. Nichols DG, Scharf SM, Robotham JL, Traystman RJ. Correlation of left phrenic artery flow with regional diaphragmatic blood flow. J Appl Physiol 1988; 64:2230-2235. PMID: 3391923
43. Scharf SM, Tow DE, Miller MJ, Brown R, McIntyre K, Dilts C. Influence of posture and abdominal pressure on the hemodynamic effects of Mueller's maneuver. J Crit Care 1989; 4:26-34.
44. Pope A, Scharf SM, Brown R. Diaphragm metabolism during supramaximal phrenic nerve stimulation. J Appl Physiol 1989; 66:567-572. PMID: 2708189
45. Scharf SM, Brown R, Warner KG, Khuri S. Intrathoracic pressures and left ventricular configuration with respiratory maneuvers. J Appl Physiol. 1989; 66:481-491. PMID: 2645265
46. Scharf SM, Warner KG, Brown R, Khuri S. Pericardial closure decreases right ventricular load tolerance in the dog. J Crit Care, 1990; 5:20-26.
47. Scharf SM, Garshick E, Brown R, Tishler PV, Tosteson T, McCarley R. Screening for subclinical sleep-disordered breathing. Sleep, 1990:13:344-353. PMID: 2267477
48. Tarasiuk A, Scharf SM, Miller MJ. Effect of chronic resistive loading on inspiratory muscles in rats. J Appl Physiol, 1991: 70:216-222. PMID: 2010379
49. Khilnani S, Graver LM, Balaban K, Scharf SM. Effects of inspiratory loading on left ventricular myocardial blood flow and metabolism. J Appl Physiol. 1992; 72:1488-1492. PMID: 1592741
50. Scharf SM, Graver LM, Khilnani S, Balaban K. Respiratory phasic effects of inspiratory loading in left ventricular hemodynamics in vagotomized dogs. J Appl Physiol, 1992; 73:995-1003. PMID: 1400068
51. Manning HL, Brown R, Scharf SM, Leith DE, Weiss JW, Weinberger SE, Schwartzstein RM. ventilatory and P0.1 response to hypercapnia in quadriplegia. Resp Physiol, 1992; 89:97-112. PMID: 1518990
52. Manning HL, McCool D, Scharf SM, Brown R. Oxygen cost of resistive loaded breathing in quadriplegia. J Appl Physiol, 1992; 73:825-831. PMID: 1400044
53. Knaupp W, Khilnani S, Sherwood J, Scharf SM, Steinberg H. Erythropoietin response to acute normobaric hypoxia in humans. J Appl Physiol, 1992; 73:837-840.
54. Scharf SM, Graver LM, Balaban K. Cardiovascular effects of periodic upper airways occlusion in dogs. Am Rev Resp Dis 1992; 146:321-329. PMID: 1489119
55. Tarasiuk A, Scharf SM. Effects of periodic obstructive apneas on venous return in closed chest dogs. Am Rev Resp Dis 1993; 148 :323-329. PMID: 8342894
56. Greenberg H, Scharf SM, Green H. Nortryptyline induced depression of ventilatory control in a patient with chronic obstructive pulmonary disease. Am Rev Resp Dis 1993; 147:1303-1305. PMID: 8484648
57. Salejee I, Tarasiuk A, Reder I, Scharf SM. Chronic upper airways obstruction produces right but not left ventricular hypertrophy in rats. Am Rev Resp Dis 1993; 148: 1346 - 1350. PMID: 8239174
58. Greenberg HE, Scharf SM. Depressed ventilatory load compensation in sleep apnea: reversal by nasal CPAP. Am Rev Resp Dis 1993; 148:1610-1615. PMID: 8256910
59. Genovese J, Moskowitz M, Tarasiuk A, Graver LM, Scharf SM. Effects of CPAP on cardiac output in normal and hypervolemic unanesthetized pigs. Am J Resp Crit Care Med 1994; 150: 752 - 758. PMID: 8087348
60. Tarasiuk A, Scharf SM. Cardiovascular effects of periodic obstructive and central apneas in dogs. Am J Resp Crit Care Med 1994; 150:83-89. PMID: 8025778
61. Tarasiuk A, Sofer S, Huberfeld S, Scharf SM. Hemodynamic effects following injection of venom from the scorpion Leiuris Quinquestriatus. J Crit Care 1994; 9: 134-140. PMID: 7920980
62. Rao RS, Graver ML, Urivetsky M, Scharf SM. Mechanisms of myocardial depression following bolus injection of sodium bicarbonate. J Crit Care 1994; 9: 255-261. PMID: 7889135
63. Bloch H, Silverman R, Mancherje N, Arsove P, Grant S, Jagminas L, Scharf SM. Intravenous magnesium as an adjunct in the treatment of acute asthma. Chest 1995; 107:1576-1581. PMID: 7781349
64. Tarasiuk A, Scharf SM. Mechanism of circulatory depression during simulated central apneas in the anesthetized dog. J Basic and Clinical Physiol and Pharm 1994; 5: 253 - 67. PMID: 8736035
65. Huberfeld S, Genovese J, Tarasiuk A, Scharf SM. Effects of CPAP on pericardial pressure, transmural left ventricular pressures and respiratory mechanics in hypervolemic unanesthetized pigs. Am J Resp Crit Care Med 1995; 152: 142-7. PMID: 7599813
66. Pokala P, Llanera M, Sherwood J, Scharf SM, Steinberg H. Erythropoietin response in subjects with obstructive sleep apnea. Am J Resp Crit Care Med 1995;151:1862-5. PMID: 7767532
67. Greenberg HE, Tarasiuk A, Rao RS, Kupferman M, Kane N, Scharf SM. Effect of chronic resistive loading on ventilatory control in a rat model. Am J Resp Crit Care Med 1995; 152: 666 - 76. PMID: 7633724
68. Genovese J, Huberfeld S, Tarasiuk A, Moskowitz M, Scharf SM. Effects of CPAP on cardiac output in pigs with pacing induced congestive heart failure. Am J Resp Crit Care Med 1995; 152: 1847 - 53. PMID: 8520745
69. Weiss JR, Pietra GG, Scharf SM, Primary pulmonary hypertension and the human immunodeficiency virus: report of 2 cases and a review of the literature. Arch Int Med 1995; 155: 2350-54. PMID: 7487262
70. Greenberg HE, Ney G, Scharf SM, Ravdin L, Hilton E. Sleep quality in Lyme Disease. Sleep 1995; 18: 912-16. PMID: 8746401
71. Cohen R, Huberfeld S, Genovese J, Steinberg HN, Scharf SM. A comparison between the effects of nitric oxide synthase inhibition and fluid resuscitation on myocardial function and metabolism in endotoxemic dogs. J Crit Care 1996; 11:27 - 36. PMID: 8904281
72. Scharf SM, Chen L, Slamowitz D, Rao PS. Effects of continuous positive airway pressure on cardiac output and plasma norepinephrine in sedated pigs. J Crit Care 1996; 11: 57-64. PMID: 8727027
73. Huberfeld SI, Genovese J, Patel U, Scharf SM. Myocardial Mechanics and energetics during CPAP in sedated pigs. Crit Care Med 1996; 24: 2027 - 2034. PMID: 8968272
74. Cohen RI, Chen L, Scharf SM. The Effects of High Dose NG-Nitro-L-Arginine Methyl Ester On Myocardial Blood Flow and Left Ventricular Function In Dogs. J Crit Care 1996; 11: 206 - 213. PMID: 8977997
75. Sofer S, Cohen R, Shapir Y, Chen L, Colon A, Scharf SM. Scorpion venom leads to gastrointestinal ischemia in spite of increased oxygen delivery in pigs. Crit Care Med 1997; 25: 834 - 840. PMID: 9187604
76. Greenberg HE, Rao RS, Sica AL, Scharf SM. Effect of chronic resistive loading on hypoxic ventilatory responsiveness. J Appl Physiol 1997; 82: 500 - 507. PMID: 9049729
77. Greenberg HE, Scharf M, Mendelson W, Cook JM, Cox E, Scharf SM. Effect of β-Carboline, 3-carboxylate-t-butyl ester on ventilatory control. Life Sciences, 1997; 60: 485 - 492. PMID: 9042377
78. Rao RS, Greenberg HE, Sica AL, Scharf SM. Gamma-Aminobutyric acid modulates cardiorespiratory control during chronic ventilatory loading. Resp Physiol 1997; 108: 35 - 44. PMID: 9178375
79. Tarasiuk A, Chen L, Scharf SM. Effects of periodic obstructive apnoeas on superior and inferior venous return in dogs. Acta Phys Scan 1997; 161: 187 - 194. PMID: 9366961
80. Chen L, Scharf SM. Comparative hemodynamic effects of periodic obstructive and simulated central apneas in sedated pigs. J Appl Physiol 1997; 83: 485 - 494. PMID: 9262444
81. Scharf SM, Rossoff L, Graver LM, McKeon K, Graham C, Steinberg H. Changes in pulmonary mechanics following lung volume reduction surgery. Lung 1998; 176: 191 - 204. PMID: 9638639
82. Cohen RI, Shapir Y, Chen L, Scharf SM. Right ventricular overload causes the drop in cardiac output following nitric oxide synthesis inhibition in endotoxemia. Crit Care Med 1998; 26: 738-747. PMID: 9559613
83. Chen L, Sica AL,Greenberg H, Scharf SM. Role of hypoxemia and hypercapnia in acute cardiovascular response to simulated central apneas in sedated pigs. Resp Phys 1998; 111: 257 - 269. PMID: 9628231
84. Chen L, Scharf SM. Systemic and myocardial hemodynamics during periodic obstructive apneas in sedated pigs. J Appl Physiol 1998; 84: 1289-1298. PMID: 9516195
85. Multz AS, Chalfin DB, Samson I, Dantzker DR, Fein AM, Steinberg HN, Neiderman MS, Scharf SM. A “closed” medical intensive care unit (MICU) improves resource utilization whem compared to an “open” unit. Am J Resp Crit Care Med 1998; 157: 1468 - 1473. PMID: 9603125
86. Weg IL, Rossoff L, McKeon K, Graver LM, Scharf SM. Development of pulmonary hypertension after lung volume reduction surgery. Am J Resp Crit Care Med 1999; 159: 552 - 556. PMID: 9927372
87. Greenberg HE, Sica A, Batson D, Scharf SM. Chronic intermittent hypoxia increases sympathetic responsiveness to hypoxia and hypercapnia. J Appl Physiol 1999; 86: 298 - 305. PMID: 9887143
88. Greenberg HE, Sica AL, Scharf SM, Ruggiero DA. Expression of c-fos in the rat brainstem after chronic intermittent hypoxia. Brain Res 1999; 816: 638 - 645. PMID: 9878890
89. Chen L, Sica AL, Scharf SM. Mechanisms of acute cardiovascular response to periodic apneas in sedated pigs. J Appl Physiol 1999; 86: 1236 - 1246. PMID: 10194209
90. Slamowitz D, Chen L, Scharf SM. Effects of vagotomy on cardiovascular response to periodic apneas in sedated pigs. J Appl Physiol 1999; 86: 1890 - 1896. PMID: 10368353
91. Iqbal M, Rossoff L, McKeon K, Graver LM, Scharf SM. Development of a giant bulla after lung volume reduction surgery. Chest 1999; 116:1809-1811. PMID: 10593810
92. The National Emphysema Treatment Trial Research Group. Rationale and design of the national emphysema treatment trial (NETT): a prospective randomized trial of lung volume reduction surgery. J Thor Cardiovasc Surg 1999; 118: 518 - 528.
93. The National Emphysema Treatment Trial Research Group. Rationale and design of the national emphysema treatment trial. A Prospective randomized trial of lung volume reduction surgery. Chest 1999; 116: 1750 - 1761.
94. Chen L, Shi Q, Scharf SM. Hemodynamic effects of obstructive apneas in sedated pigs with congestive heart failure. J Appl Physiol 2000; 88: 1051 - 1060. PMID: 10710403
95. Afulukwe IF, Cohen RI, Zeballos GA, Iqbal M, Scharf SM. Selective NOS inhibition restores myocardial contractility in endotoxemic rats; however myocardial NO content does not correlate with myocardial dysfunction. Am J Resp Crit Care Med 2000; 162: 21 - 26. PMID: 10903214
96. Cohen RI, Shapir Y, Davis A, Loona R, Scharf SM. Comparison between selective, non-selective nitric oxide synthase inhibition and phenylephrine in normal and endotoxic swine. Crit Care Med 2000, 28: 3257 - 3267. PMID: 11008990
97. Chen L, Scharf SM. Effects of aortic nerve on hemodynamic response to obstructive apnea in sedated pigs. J Appl Physiol 2000; 89: 1455 - 1461. PMID: 11007582
98. Sica AL, Greenberg HE, Scharf SM, Ruggiero DA. Immediate-early gene expression in cerebral cortex following exposure to chronic-intermittent hypoxia. Brain Res 2000; 870: 204 - 210. PMID: 10869520
99. Sica AL, Greenberg HE, Scharf SM, Ruggiero DA. Chronic-intermittent hypoxia induces immediate early gene expression in the midline thalamus and epithalamus. Brain Res 2000; 883: 224 - 228. PMID: 11074051
100. The National Emphysema Treatment Trial Research Group. Rational and design of the National Emphysema Treatment Trial (NETT): A prospective randomized trial of lung volume reduction surgery. J Cardiopulm Rehab 2000; 20: 24 – 36.
101. Cohen RI, Hassell A-M, Marzouk K, Marini C, Liu S-F, Scharf SM. Renal effects of nitric oxide in endotoxemia. Am J Resp and Crit Care Med. 2001; 164: 1890 – 1895. PMID: 11734442
102. Castro M, Dozor A, Fish J, Irvin C, Scharf SM, Scheipeter ME, Holbrook J, Tonascia J, Wise R (Writing Committee for the American Lung Association Asthma Clinical Research Centers). Safety of inactivated influenza vaccine in children and adults with asthma. New Eng J Med 2001; 345: 1529 – 1536.
103. National Emphysema Treatment Trial Research Group: Patients at high risk after lung volume reduction surgery. N Engl J Med 2001; 345:1075-1083
104. Fessler, HE, Scharf SM, Permutt S. Improvement in spirometry following LVRS. Application of a physiologic model. Am J Resp Crit Care Med 2002; 165:34-40. PMID: 11779727
105. Scharf SM, Iqbal M, Keller C, Criner G, Lee S, Fessler HE. Hemodynamic characterization of patients with severe emphysema. Am J Resp Crit Care Med 2002;166: 314-322. PMID: 12153963
106. Silverman R, Osborn H, Runge J, Gallagher EJ, Chiang W, Feldman J, Gaeta T, Freeman K, Levin B, Mancherje N, Scharf SM. Intravenous magnesium sulfate in the treatment of acute severe asthma: A multicenter randomized controlled trial. Chest 2002; 122: 489-497.
107. Cohen RI, Marzouk K, Berkoski P, O’Donnell CP, Polotsky VP, Scharf SM. Body composition and resting energy expenditure in clinically stable, non-weight losing patients with severe emphysema. Chest 2003; 124:1365 – 1372. PMID: 14555567
108. Tarasiuk A, Afulukwe IF, Scharf SM. The effect of scorpion venom on isolated rat papillary muscle. Cardiovascular forum online. August 2003: 0029-0036. (ehi.at).
109. Scharf SM, Seiden L, DeMore J, Carter-Pokras O. Racial differences in clinical presentation of patients with sleep disordered breathing. Sleep and Breathing 2004; 8: 173-183. PMID: 15611892
110. Scharf SM, DeMore J, Landau T, Smale P. Comparison of Primary Care Practitioners and sleep specialists in the treatment of obstructive sleep apnea. Sleep and Breathing 2004; 8: 111 - 124. PMID: 15389385
111. Scharf SM, Tubman A, Smale P. Prevalence of Concomitant Sleep Disorders in Patients with Obstructive Sleep Apnea. Sleep and Breathing 2005; 9: 50-56. An editorial on this paper was published in the same issue. PMID: 15803318
112. Chen L, Einbinder E, Zhang Q, Hasday J, Balke WC, Scharf SM. Oxidative Stress and Left Ventricular Function with chronic intermittent hypoxia in rats. Am J Resp Crit Care Med 2005; 172: 915-920. PMID: 15976378
113. Finkelstein J, Shaya FT, Arora M, Joshi A, Samant N, Scharf SM. Automated Survey collector (ASC): A Universal Platform for Interactive Collection of Clinical Data. J Systemics, Cybernetics and Informatics 2006; Vol 3 (1). Online journal.
114. Roth MD, Connett JE, D’Armiento JM, Foronjy Rf, Friedman PJ, Goldin JG, Louis TA, Mao JT, Muindi JR, O’Connor GT, Ransdell JW, Ries AL, Scharf SM, Schluger NW, Sciurba FC, Skeans MA, Walter RE, Wendt CH, Wise RA. Feasibility of Retinoids for the Treatment of Emphysema (FORTE) Study. CHEST 2006; 130: 1334 – 1345. PMID: 17099008
115. Shaya FT, El Khoury AC, Samant ND, Scharf SM. Utilization of Health Care Resources in a high-risk Medicaid population with chronic obstructive pulmonary disease. P&T 2006; 31: 261-268. (online journal).
116. Shaya FT, Samant ND, Pradel FG, Mullins CD, Scharf SM, Britt EJ. Health-related quality of life as potential predictor in COPD patients. Expert Review of Pharmacoeconomics & Outcomes Research, April 2007; 7: 129-135. PMID: 20528439
117. Welch K, Scharf SM. Construct Validity for the Health Utilities Index in a Sleep Center. Sleep and Breathing 2007; 11: 295 – 303. PMID: 17457630
118. Criner GJ , Scharf SM, Falk JA, Gaughan JP, Sternberg AL, Namrata PB, Fessler HE, Minai OA, Fishman AP. Effect of Lung Volume Reduction Surgery on Resting Pulmonary Hemodynamics in Severe Emphysema. Am J Resp Crit Care Med 2007; 176: 253-260. PMID: 17496227
119. Fisher M, Criner GJ, Fishman AF, Hassoun PM, Minai OA, Scharf SM, and Fessler HE. Estimating Pulmonary Artery Pressures by Echocardiography in Patients with Emphysema. Eur Respir J. 2007 30: 914-921. PMID: 17652313
120. Falk J, Martin UJ, Scharf S, Criner CJ. Lung Elastic Recoil Does Not Correlate with Pulmonary Hemodynamics in Severe Emphysema. Chest 2007; 132: 1476-1484.
121. Chen-Izu Y, Chen L, Bányász T, McCulle SL, Norton B, Scharf SM, Agarwal A, Patwardhan A, Izu LT, Balke CW. Hypertension-induced remodeling of cardiac excitation-contraction coupling in ventricular myocytes occurs prior to hypertrophy development. Am J Physiol Heart Circ Physiol. 2007; 293: H3301 – 3310. PMID: 17873027
122. Mastronarde JG, Wise RA, Shade DM, Olopade CM, Scharf SM. Sleep Quality in Asthma: Results of a Large Prospective Clinical Trial. J Asthma 2008; 45: 183 - 189. PMID: 18415823
123. Chen L, Zhang J, Gan TX, Chen-Izu Y, Hasday JD, Karmazyn M, Balke CW, Scharf SM. Left ventricular dysfunction and associated cellular injury in rats exposed to chronic intermittent hypoxia. J Appl Physiol 2008; 104: 218 – 223. PMID: 18006871
124. Witting MD, Scharf SM. Diagnostic Room-Air Pulse Oximetry: Effects of Smoking, Race, and Gender. Am J Emerg Med 2008; 26: 131 – 136. PMID: 18272090
125. Shaya F, Du D, Akazawa MO, Blanchette CM, Wang J, Mapel DW, Dalal A. Scharf SM. Burden of Concomitant Asthma and COPD in a Medicaid Population. Chest 2008; 134: 14 - 19. PMID: 18339789
126. Ramagopal M, Scharf SM, Roberts DW, Blaisdell C. Obstructive sleep apnea and history of asthma in snoring children. Sleep and Breathing 2008; 12: 381 - 392. PMID: 18421491
127. O’Hearn DJ, Gold AR, Gold MS, Diggs P, Scharf SM. Lower Extremity Edema and Pulmonary Hypertension in Morbidly Obese Patients with Obstructive Sleep Apnea. Sleep and Breathing 2009;13:25-34. PMID: 18615260
128. Alattar M, Scharf SM. Opioid associated central sleep apnea. Sleep and Breathing 2009; 13:201-206. PMID: 18807080
129. Shaya FT, Maneval MS, Confidence MG, Sohn K, Dalal AA, Du D, Scharf SM. Burden of asthma, COPD, and comocomitant COPD and asthma among adults : racial disparities in a Medicaid population. Chest. 2009; 136:405 - 411. [Mar 24 - Epub ahead of print] PMID: 19318663
130. Shaya FT, Lin PJ, Aljawadi MH, Scharf SM. Elevated Economic Burden in Obstructive Lung Disease Patients with Concomitant Sleep Apnea Syndrome. Sleep Breath. 2009, 13: 317 - 323 [Epub ahead of print]. An editorial on this paper was published in the same issue. PMID: 19484281
131. Hecht A, Ma S, Proszasz J, Casaburi R. (writing committee for COPD clinical research network, Scharf SM listed as collaborator. Methodology for Using Long-Term Accelerometry Monitoring to Describe Daily Activity Patterns in COPD. COPD 2009; 6: 121-129. PMID: 19378225
132. Ramagopal M, Mehta A, Roberts DW, Wolf JS, Taylor RJ, Mudd KE, Scharf SM. Asthma as a predictor of obstructive sleep apnea in urban African-American children. J Asthma 2009; 46: 895-899. PMID: 19905914
133. Finkelstein J, Cha E, Scharf SM. Chronic obstructive pulmonary disease as a risk factor for cardiovascular morbidity. Int J COPD. 2009; 4: 337 – 349. [Epub 2009 Sep 24] PMID: 19802349
134. D'Armiento JM, Scharf SM, Roth MD, Connett JE, Ghio A, Sternberg D, Goldin JG, Louis TA, Mao JT, O'Connor GT, Ramsdell JW, Ries AL, Schluger NW, Sciurba FC, Skeans MA, Voelker H, Walter RE, Wendt CH, Weinmann GG, Wise RA, Foronjy RF. Eosinophil and T cell Markers Predict Functional Decline in COPD Patients. Respiratory Research 2009; 10:113 . [Epub ahead of print]. PMID: 19925666
135. Williams AL, Chen L, Scharf SM. Effects of allopurinol on cardiac function and oxidant stress in chronic intermittent hypoxia. Sleep Breath. 2010; 14: 51 - 57. [Epub 2009 Jul 15]. PMID: 19603215
136. Matsuoka S, Washko GR, Yamashiro T, San Jose ER, Diaz A, Silverman EK, Hoffman E, Fessler HE, Criner GJ, Marchetti N, Scharf M, Martinez FJ, Reilly JJ, Hatabu H. Pulmonary hypertension and CT measurement of small pulmonary vessels in severe emphysema. AJRCCM 2010; 181: 218 - 225 [epub 2009, Oct 29]. PMID: 19875683
137. Lin PJ, Shaya FT, Scharf SM. Economic Implications of Comorbid Conditions among Medicaid Beneficiaries with COPD. Respir Med. 2010 May;104(5):697-704. [Epub 2009 Dec 2]. PMID: 19954941
138. Coursey DC, Scharf SM, Johnson AT. Comparing pulmonary resistance measurements with an esophageal balloon to resistance measurements with an airway perturbation device. Physiol Meas 2010; 31: 921 - 934. [epub ahead of print]. PMID 20526028
139. Chen L, Zhang J, Hu X, Philipson KD, Scharf SM. The Na+/Ca2+ exchanger mediates left ventricular dysfunction in mice with chronic intermittent hypoxia. J Appl Phys 2010, 109 (6): 1675-1685. Oct [Epub ahead of print; 2010; Oct 14] PMID: 20947716
140. Lam JC, Mahone EM., Mason TBA, Scharf SM. Defining the Roles of Actigraphy and Parent Logs for Assessing Sleep Variables in Preschool Children. Behavioral Sleep Medicine, 2011; 9: 184 – 193. PMID: 21722013
141. Lam JC, Mahone EM., Mason TBA, Scharf SM. The Effects of Napping on Cognitive Function in Preschoolers. J Behav Developmental Pediatrics. 2011; 32: 90 - 97 [Epub ahead of print Jan 6.] PMID: 21217402
142. Coursey DC, Scharf SM, Johnson AT. Comparison of the expiratory isovolume pressure flow relationship generated with stop-flow and esophageal balloon methods. Resp Care. 2011; 56: 969 -975 [epub ahead of print Feb 21]. PMID: 21352665
143. Woodruff P, Albert R, Bailey W, Casaburi R, Connet J, Cooper J, Criner G, Curtis J, Dransfield M, Han M, Harnden S, Kim V, Marchetti N, Martinez F, McEvoy C, Niewoehner D, Reilly J, Rice K, Scanlon P, Scharf SM, Sciurba F, Washko G, Lazarus S. Randomized Trial of Zileuton for Treatment of COPD Exacerbations Requiring Hospitalization. COPD 2011; 8: 21-29. PMID: 21299475
144. Scharf SM, Maimon N, Simon-Tuval T, Bernhard-Scharf B, Reuveni H, Tarasiuk A. Sleep Quality predicts Quality of Life in Chronic Obstructive Pulmonary Disease. Int J COPD 2010; 6: 1 – 12. PMID: 21311688
145. Simon-Tuval T, Scharf SM, Maimon N, Bernhard-Scharf B, Reuveni H, Tarasiuk A. Determinants of elevated health care utilization in patients with COPD. Respiratory Research 2011; Jan 13;12(1):7 - 15. [Epub ahead of print]. PMID: 21232087
146. Diaz-Abad M, Verceles AC, Brown JE, Scharf SM. Sleep Disordered Breathing May Be Under-Recognized in Patients Who Wean From Prolonged Mechanical Ventilation. Resp Care 2012. 57: 229 – 237. PMID: 21762560
147. Albert RK, Connett J, Bailey WC, Casaburi R, Cooper JAD, Criner GJ, Curtis JL, Dransfield MT, Han MK, Lazarus SC, Make B, Marchetti N, Martinez FJ, Madinger NE, McEvoy C, Niewoehner DE, Porsasz J, Price CS, Reilly J, Scanlon PD, Sciurba FC, Scharf SM, Washko GR, Woodruff PG, Anthonisen NR, Azithromycin for Prevention of COPD Exacerbations. New Eng J Med 2011; 365: 689 – 698. PMID 21864166
148. Come CE, Divo MJ, San José Estépar R, Sciurba FC, Criner GJ, Marchetti N, Scharf SM, Mosenifar Z, Make BJ, Keller CA, Minai OA, Martinez FJ, Han MK, Reilly JJ, Celli BR, Washko GR; for the NETT Research Group. Lung Deflation and Oxygen Pulse in COPD. Results from the NETT randomized trial. Resp Med 2011; Aug 13 [Epub ahead of print]. PMID 21843930
149. Casaburi R, Porszasz J, Hecht A, Tiep B, Albert R, Antonisen N, Bailey W, Connett J, Cooper JA, Criner G, Curtis J, Dransfield M, Lazarus S, Make B, Martinez F, McEvoy C, Niewoehner D, Reilly J, Scanlon P, Scharf SM, Sciurba F, Wordruff P. Influence of lightweight ambulatory oxygen on oxygen use and activity patterns of COPD patients receiving long-term oxygen therapy. J COPD 2012 Feb;9(1):3-11. PMID: 22292592
150. Reed R, Hashmi S, Eberlein M, Iacono A, Netzer G, DeFillippis A, Girgis RE, Toth PP, Scharf S, Jones S. Impact of Lung Transplantation on Serum Lipids in COPD. Respir Med. 2011; 105: 1961-1968. Epub 2011 Oct 21PMID 22019328
151. Geiger-Brown J, Rogers VE, Trinkoff A, Kane R, Bausell R, Scharf SM. Sleep, sleepiness, fatigue and performance in 12-hour shift nurses. Chronobiology International (2012); 29(2), 211-219. PMID 26969658
152. Kunisaki KM, Niewoehner DE, Connett JE; COPD Clinical Research Network. Vitamin D levels and risk of acute exacerbations of chronic obstructive pulmonary disease: a prospective cohort study. AJRCCM 2012; 185: 286 - 290. Epub 2011 Nov 10. PMID: 22077070 listed as collaborator.
153. Verceles AC, Silhan L, Terrin M, Netzer G, Shanholtz C, Scharf SM. Circadian rhythm disruption in severe sepsis: the effect of ambient light on urinary 6-sulfatoxymelatonin secretion. Intensive Care Med. 2012; 38:804–810. [Epub ahead of print Jan 28, 2012]; PMID: 22286671
154. Geiger-Brown J, Rogers VE, Han K, Trinkoff AM, Bausell RB, Scharf SM. Occupational Screening for Sleep Disorders in 12-hour Shift Nurses Using the Berlin Questionnaire. Sleep and Breathing 2013; 17: 381 – 388. [epub ahead of print 4/26/2012]. PMID 22535196
155. Verceles A, Lechner E, Halpin D, Scharf SM. The Association Between Comorbid Illness, Colonization Status and Acute Hospitalization In Patients Receiving Prolonged Mechanical Ventilation. Resp Care 2012, June 15 [epub ahead of print]. PMID 22709565
156. Kim V, Kretschman DM, Sternberg AL, DeCamp MM Jr, Criner GJ; National Emphysema Treatment Trial Research Group. Weight gain after lung reduction surgery is related to improved lung function and ventilatory efficiency. Am J Respir Crit Care Med. 2012 Dec 1;186(11):1109-1116. Epub 2012 Aug 9. Listed as collaborator. PMID: 22878279
157. Reed R, Eberlein M, Girgis RE, Hashmi S, Iacono A, Jones S, Netzer G, Scharf SM. Coronary Artery Disease is Under-Diagnosed and Under-Treated in Advanced Lung Disease. Am J Med. 2012; Sep 5. [Epub ahead of print] PMID: 22959785
158. Verceles AC, Diaz-Abad M, Geiger-Brown J, Scharf SM. Testing the Predictive Value of the Rapid Shallow Breathing Index in Patients Requiring Prolonged Mechanical Ventilation. Heart & Lung, 2012 Jul 6. [Epub ahead of print]. PMID 22770598
159. Dransfield MT, Harnden S, Burton RL, Albert RK, Bailey, WC, Casaburi R, Connett J, Cooper JAD, Criner GJ, Curtis JL, HAN MK, Make B, Marchetti N, Martinez FJ, McEvoy C, Nahm MH, Niewoehner DE, Porszasz J, Reilly J, Scanlon PD, Scharf SM, Sciurba FX, Washko GR, Woodruff PG, Lazarus SC. Long Term Comparative Immunogenicity of Protein Conjugate and Free Polysaccharide Pneumococcal Vaccines in COPD. Clin Infect Dis. 2012 May 31. [Epub ahead of print]. PMID 22652582.
160. Verceles AC, Liu X, Terrin ML, Scharf SM, Shanholtz C, Harris A, Ayanleye B, Parker A, Netzer G. Ambient light levels and critical care outcomes. J Crit Care. 2013; Feb;28(1):110.e1-8. doi: 10.1016/j.jcrc.2012.04.012. Epub 2012 Jul 2. PMID: 22762935
161. Davis MD, Livingston M, Scharf SM. Reversal of central sleep apnea following discontinuation of opioids. J Clin Sleep Med 2012; 8: 579 – 580. PMID: 23066372
162. Breunig IM, Shaya FT, Scharf SM. Delivering Cost-Effective Care for COPD in the United States: Recent progress and current challenges, Expert Review of Pharmacoeconomic and Outcomes Research, December 2012; 12 (6): 725 – 731. PMID: 23252355
163. Chandra D, Wise RA, Kulkarni HS, Benzo RP, Criner G, Make B, Slivka WA, Ries AL, Reilly JJ, Martinez FJ, Sciurba FC; NETT Research Group. Optimizing the 6-min walk test as a measure of exercise capacity in COPD. Chest 2012; 142: 1545 - 1552. Listed as collaborator. PMID: 23364913
164. Romem A, Iacono A, McILmoyle E, Patel KP, Reed RM, Verceles AC, Scharf SM. Obstructive sleep apnea in patients with end-stage lung disease. J Clin Sleep Med 2013; 9: 687-693. PMID 23453563
165. D’Armiento JM, Goldklang MP, Hardigan AA, Geraghty P, Roth MD, Connett JE, Wise RA, Sciurba FC, Scharf SM, Thankachen J, Islam M, Ghio AJ, Foronjy RF. Increased Matrix Metalloproteinase (MMPs) Levels Do Not Predict Disease Severity or Progression in Emphysema. PLoS ONE 2013; 8: e56352. PMID: 23441181
166. Haque T, Vossoughi J, Johnson AT, Bell-Farrell W, Fitzgerald T, Scharf SM. Resistance measured by Airflow Perturbation compared with standard pulmonary function measures. Open Journal of Respiratory Diseases, 2013, 3, 63-67; doi:10.4236/ojrd.2013.32010 Published Online May 2013 ().
167. Greenberg-Dotan S, Reuveni H, Tal A, Oksenberg A, Cohen A, Shaya FT, Tarasiuk A, Scharf SM. Increased Prevalence of Obstructive Lung Disease in Patients with Obstructive Sleep Apnea. Sleep and Breathing, 2014; 18: 69 - 75; PMID 23733255.
168. Koldobskiy D, Diaz-Abad M, Scharf SM, Brown J, Verceles AC. Long term acute care patients weaning from prolonged mechanical ventilation maintain circadian rhythm. Resp Care 2014; 59(4): 518 - 524. PMID 24026184.
169. Mistry NN, Diwanji T, Shi X, Pokharel S, Feigenberg S, Scharf SM, D'Souza WD. Evaluation of Fractional Regional Ventilation Using 4D-CT and Effects of Breathing Maneuvers on Ventilation. Int J Radiat Oncol Biol Phys. 2013; 15; 87: 825 - 831. PMID 24064319
170. Kim V, Sternberg AL, Washko G, Make BJ, Han MK, Martinez F, Criner GJ; National Emphysema Treatment Trial Research Group. Severe chronic bronchitis in advanced emphysema increases mortality and hospitalizations. COPD. 2013; 10: 667 - 678. PMID 23978192. Listed as collaborator
171. Benzo R1, Siemion W, Novotny P, Sternberg A, Kaplan RM, Ries A, Wise R, Martinez F, Utz J, Sciurba F; National Emphysema Treatment Trial Research Group. Factors to inform clinicians about the end of life in severe chronic obstructive pulmonary disease. J Pain Symptom Manage. 2013; 46: 491 – 499. PMID 23522520. Listed as collaborator
172. Koldobskiy D, Groves S, Scharf SM, Cowan M. Validation of Factors Affecting the Outcome of Cardiopulmonary Arrest in a Large, Urban, Academic Medical Center, J Critical Care Medicine, Sept 11; [Epub ahead of print]; 2014; Article ID 168132, 7 pages;
173. Minai OA, Fessler H, Stoller JK, Criner GJ, Scharf SM, Meli Y, Nutter B, Decamp MM. Clinical characteristics and prediction of pulmonary hypertension in severe emphysema. Respir Med. 2014; 108: 482 - 490. PMID: 24290900
174. Woodruff PG, Chatila W, Connett JE, Criner GJ, Curtis JL, Dransfield MT, Han MK, Lazarus SC, Marchetti N, Rogers TJ, Scanlon PD, Sin DD, Voelker H, Wendt C, Albert RK; COPD Clinical Research Network. Tumour necrosis factor receptor-75 and risk of COPD exacerbation in the azithromycin trial. Eur Respir J 2014; 43: 295 - 298. PMID: 24136332. Listed as collaborator.
175. Geiger-Brown J, Wieroney M, Blair L, Zhu S, Warren J, Scharf SM, Hinds PS. Measuring subjective sleepiness at work in hospital nurses: Validation of a modified delivery format of the Karolinska Sleepiness Scale. Sleep Breath. 2014 Dec;18(4):731-9. doi: 10.1007/s11325-013-0935-z. Epub 2014 Jan 29 24474446
176. Romem A, Romem A, Koldobskiy D, Scharf SM. Diagnosis of obstructive sleep apnea using pulse oximeter derived photoplethysmographic signals. J Clin Sleep Med 2014; 10: 285 - 290.
177. Criner GJ, Connett JE, Aaron SD, Albert RK, Bailey WC, Casaburi R, Cooper JAD, Curtis JL, Dransfield MT, Han MK, Make B, Marchetti N, Martinez FJ, Niewoehner DE, Scanlon PD, Sciurba FC, Scharf SM, Sin DD, Voelker H, Washko GR, Woodruff PG, Lazarus SC. for the NHLBI COPD Clinical Research Network and the Canadian Institute of Health Research. Simvastatin for the prevention of exacerbations in moderate-to-severe COPD. N Engl J Med. 2014 Jun 5; ;370(23): 2201 - 2210. doi: 10.1056/NEJMoa1403086. Epub 2014 May 18PMID 24836125
178. Reed RM, Netzer G, Hunsicker L, Mitchell BD, Rajagopal K, Scharf S, Eberlein, M. Cardiac Size and Sex Matching in Heart Transplantation: Size Matters in Matters of Sex and the Heart. JACC Heart Fail 2014; 2 (1): 73 – 83. PMID 24611131
179. Kauffman KS, Doede M, Diaz-Abad M, Scharf SM, Bell-Farrell W, Rogers VE, Geiger-Brown J. Experience of Insomnia, Symptom Attribution, and Treatment Preferences in individuals with Moderate to Severe COPD: a qualitative study. Patient Preferences and Adherence 2014; 9: 1 – 6. Dec 10;8:1699-704. doi: 10.2147/PPA.S71666. eCollection 2014. PMID: 25525346
180. Geiger-Brown J, Lindberg S, Krachman S, McEvoy C, Criner GJ, Connett JC, Albert RK, Scharf SM. Self-reported sleep quality and acute exacerbations of chronic obstructive pulmonary disease. Int J COPD 2015; 10: 389 – 397. PMID: 25759571
181. Lam JC, Koriakin TA, Scharf SM, Mason TBA, Mahone EM. Does increased consolidated nighttime sleep facilitate attentional control? A pilot study of nap restriction in preschoolers. J Attention Disorders 2015; Feb 2. pii: 1087054715569281. [Epub ahead of print] PMID: 25646024
182. Romem A, Tom SE, Beauchene M, Babington L, Scharf SM, Romem A. Pain management at the end of life: A comparative study of cancer, dementia, and chronic obstructive pulmonary disease patients. Palliat Med. 2015 Feb 13. pii: 0269216315570411. [Epub ahead of print]; PMID: 25683077
183. Assefa SZ, Diaz-Abad M, Korotinsky A, Tom SE, Scharf SM. Comparison of a simple sleep apnea screening device with standard in-laboratory polysomnography. Sleep and Breathing 2015. Aug, 2015: [epub ahead of print]. PMID 26265559
184. Dodd JW, Novotny P, Sciurba FC, Benzo RP. The NETT Research Group. Executive Function, Survival, and Hospitalization in Chronic Obstructive Pulmonary Disease. A Longitudinal Analysis of the National Emphysema Treatment Trial (NETT). Ann Am Thor Soc 2015: 12 (10): 1473 – 1481. doi: 10.1513/AnnalsATS.201506-373OC. Listed as collaborator. PMID: 26288391
185. Korotinsky A, Assefa SZ, Diaz Abad M, Wickwire E, Scharf SM. Comparison of American Academy of Sleep Medicine (AASM) versus Center for Medicare and Medicaid Services (CMS) Polysomnography (PSG) scoring rules on AHI and eligibility for Continuous Positive Airway Pressure (CPAP) treatment. Sleep and Breathing 2016, doi:10.1007/s11325-016-1327-y; PMID:26969658
186. Stoller JK, Aboussouan LS, Kanner RE, et al. For the LOTT research group. Characteristics of alpha-1-antitrypsin deficient individuals in the Long-Term oxygen treatment trial and comparison with other subjects with chronic obstructive pulmonary disease. Ann Am Thor Soc 2015; 12: 1796 – 1804. Listed as collaborator. PMID: 26653189.
Non-peer reviewed articles (Review papers)
1. Scharf SM. Mechanical effects of the respiratory system on cardiocirculatory function. Is J Med Sci. 1981; 17:715-721. PMID: 7026499
2. Robotham J, Scharf SM. The effects of positive and negative pressure ventilation on cardiac performance. Clinics in Chest Medicine 1983; 4:161-187. PMID: 6342919
3. Scharf SM. Mechanical cardiopulmonary interactions in asthma. Clin Rev in Allergy. 1985; 3:487-500. PMID: 3902189
4. Scharf SM. Cardiovascular effects of airway obstruction. Lung, 1991;169:1-23. PMID: 2011041
5. Scharf SM. Heart-Lung Interactions in Patient Care. J Crit Care. 1992; 7:63-66.
6. Scharf SM. Cardiovascular effects of positive pressure ventilation. J Crit Care 1992;7: 168 – 279
7. Scharf SM. The effects of decreased intrathoracic pressure on ventricular function. J Sleep Research 1995; 4: suppl 1: 53 - 58. PMID: 10607174
8. Greenberg HE, Genovese J, Huberfeld S, Scharf SM. Congestive heart failure and sleep apnoea - possible mechanisms and effect of CPAP therapy. J Sleep Res 1995; 4: supp 1: 130 - 134. PMID: 10607189
9. Scharf SM. Ventilatory support in cardiac failure. Current Opinion in Critical Care. 1997; 3: 71 - 77.
10. Scharf SM. Effects of continuous positive airway pressure on cardiac output in experimental heart failure. Sleep 1997; 19:S240 - S242. PMID: 9085521
11. Scharf SM. Pulmonary function testing in asthma. Emerg Med 1999; 31(3): 41 - 53.
12. Schnader J, Reddy MN, Heffner JE, Scharf SM. Clinical conference on management dilemmas; obstructive sleep apnea and respiratory failure. Chest 1999; 1786 - 1793. PMID: 10593806
13. Sica AL, Greenberg HE, Ruggiero DA, Scharf SM. Chronic-intermittent hypoxia: a model of sympathetic activation in the rat. Resp Physiol 2000; 121: 173 - 184. PMID: 10963773
14. Hey J, Scharf SM. Pulmonary Arterial Hypertension – the primary pulmonary hypertension syndromes. Is Assoc Med J. 2003; 5: 298-303. PMID: 14555567
15. Williams A, Scharf SM: Obstructive Sleep Apnea, Cardiovascular Disease, and Inflammation – Is NF-kB the key? Sleep and Breathing 2007; 11: 69-76. PMID: 17380355
16. King DA, Cordova F, Scharf SM. Nutritional Aspects of Chronic Obstructive Pulmonary Disease. Proc Am Thor Soc 2008; 5: 519 - 523. PMID: 18453365
17. Fessler HE, Scharf SM, Ingenito EP, McKenna RJ, Sharafkhaneh A. Physiologic basis for improved pulmonary function after lung volume reduction. Proc Am Thor Soc 2008; 5: 416 - 420. PMID: 18453348
18. Krachman S, Minai O, Scharf SM. Sleep abnormalities and Treatment in Emphysema. Proc Am Thor Soc 2008; 5: 536 – 542. PMID: 18453368
19. Falk JA, Kadiev S, Criner GK, Scharf SM, Minai OA, Diaz P. Cardiac Disease in Chronic Obstructive Pulmonary Disease. Proc Am Thor Soc 2008; 5: 543 - 548. PMID: 18453369
20. Shaya FT, Breunig IM, Scharf SM. The use of age-period-cohort analysis to determine the impact of economic development on COPD mortality in Hong Kong. Exp Rev Pharacoeconomics and Outcomes Res. 2012; 12: 19-21. PMID 22280192
21. Assefa SZ, Diaz-Abad M, Wickwire EM, Scharf SM. The functions of sleep. AIMS Neuroscience. 2015; 2: 155 – 171. Open Access journal.
22. Wickwire EM, Shaya F, Scharf SM. Health economics of insomnia treatment: The return on investment for a good night’s sleep. Sleep Med Rev. 2015 Nov 28;30:72-82. doi: 10.1016/j.smrv.2015.11.004. [Epub ahead of print]; 2016; 30: 72 – 82. PMID 26874067.
23. Wickwire EM, Williams SG, Roth T, Jaffe M, Moline M, Motamedi GK, Morgan GW, Mysliwiec V, Germain A, Pazdan RM, Ferziger R, Balkin TJ, MacDonald ME, Macek TA, Yochelson MR, Scharf SM, Lettieri CJ. Sleep, sleep disorders and mild traumatic brain injury. What we know, what we need to know: Findings from a national working group. Neurotherapeutics 2016, in press.
BOOKS
1. Scharf SM and Cassidy SS, eds. Heart-Lung Interactions in Health and Disease. New York: Marcel Dekker: 1989.
2. Scharf SM (ed). Cardiopulmonary Physiology for Critical Care. Marcel Dekker, New York. 1992.
3. Dantzker DR and Scharf SM, eds. Cardiopulmonary Critical Care 3rd edition. WB Saunders Inc., Philadelphia, 1998.
1. Scharf SM, Magder S, Pinsky MR, eds: Respiratory-Circulatory Interactions in Health and Disease, (2nd edition of Heart Lung Interactions). New York: Marcel Dekker, 2001.
Book Chapters
1. Bromberger-Barnea B, Scharf SM. The effects of increasing capillary perfusion pressure on cardiac contractility. In: Maseri A, ed. Myocardial blood flow in man. Methods and clinical significance. Torino. Minerva medica, 1972: 79 – 84. Chapter 4.
2. Scharf SM, Heimer D. Laboratory evaluation of patients with respiratory disease. In: Baum G, ed. Textbook of pulmonary diseases. Boston: Little Brown Co, 1983:235-247.
3. Heimer D, Scharf SM. History and physical examination. In: Baum G, ed. Textbook of pulmonary diseases. Boston: Little Brown Co, 1983:223-233.
4. Scharf SM. Influence of sleep state and breathing on cardiovascular function. In: Saunders NA, Sullivan T, eds. Sleeping and breathing. New York: Marcel Dekker, 1984:221-282.
5. Brown R, Scharf SM. Aspiration pneumonia. In: Walshe TM, ed. Clinical problems in geriatrics. Boston: Little Brown, 1985:209.
6. Brown R, Scharf SM. Pulmonary embolism. In: Walshe TM, ed. Clinical problems in geriatrics. Boston: Little Brown, 1985:210.
7. Brown R, Scharf SM. Chronic obstructive pulmonary disease. In: Walshe TM, ed. Clinical problems in geriatrics. Boston: Little Brown, 1985:211.
8. Brown R, Scharf SM. Changes in respiratory physiology in the elderly. In: Walshe TM, ed. Clinical problems in geriatrics. Boston: Little Brown, 1985:212.
9. Scharf SM. Respiratory muscles in the intensive care unit. Proc of 4th World Congress of Critical Care. Jerusalem, 1985:69-73.
10. Brown R, Scharf SM, Melia SC. Spinal cord injury. In: Kacmarek RM and Stoller JK, eds. Current Respiratory Care. Toronto: BC Dekker Inc. 1988:316-320.
11. Sasahara AA, Scharf SM, Brown R. Acute cor pulmonale, pulmonary embolism and chronic cor pulmonale. In: Luchi RJ, ed. Cardiology in the elderly. Churchill Livingston. New York, 1989:242-274.
12. Scharf SM. History and physical examination. In: Baum G, Wolinsky M, eds. Textbook of pulmonary disease. Boston: Little Brown Co, 1989:213-225.
13. Scharf SM. Laboratory evaluation of patients with respiratory diseases. In: Baum G, Wolinsky M, eds. Textbook of pulmonary disease. Boston: Little Brown Co. 1989:227-241.
14. Scharf SM. Effects of normal and stressed inspiration on cardiovascular function in Scharf SM and Cassidy SS, eds. Heart-lung interactions. New York: Marcel Dekker: 1989:427-461.
15. McIntyre K, and Scharf SM. The use of Valsalva's and Mueller's maneuvers as diagnostic tests for coronary artery disease. In Scharf SM and Cassidy SS, eds. Heart-lung interactions. New York: Marcel Dekker; 1989:1021-1046.
16. Scharf SM. Chapters 1-6, 8-10, 12-14, 15-17, 21, 23. In Scharf SM (ed) Cardiopulmonary Physiology for Critical Care. Marcel Dekker, N.Y. 1992.
17. Podszus TE, Greenberg H, Scharf SM. Influence of sleep state and sleep-disordered breathing on cardiovascular function. In Sullivan CE, and Saunders NA (eds). Sleep and Breathing II. Marcel Dekker, N.Y. 1993; pp 257-310.
18. Scharf SM, Greenberg H. The normal adult pulmonary circulation. In Baum G and Wolinsky E (eds). Textbook of pulmonary diseases. Little Brown Co., Boston, 1993, pp. 1265 - 1284.
19. Greenberg H, Scharf SM. Pulmonary hypertension, pathophysiology and clinical disorders. In Baum G and Wolinsky E (eds). Textbook of pulmonary diseases. Little Brown Co., Boston, 1993, pp. 1285 - 1304.
20. Llanera M, Greenberg, H, Scharf SM. Pulmonary Heart Disease. In Baum G and Wolinsky E (eds). Textbook of pulmonary diseases. Little Brown Co., Boston, 1993, pp. 1327 - 1344.
21. Scharf SM. Right ventricular load response: importance of left ventricular function. In: Perret C and Feihl F (eds). Les interactions cardiopulmonaires. 1994; Arnette, Paris, pp17 – 28.
22. Scharf SM. Pulmonary Heart Disease. In Rapaport E (ed). Cardiology and co-existing disease. Churchill Livingston, New York, 1994; pp 11 - 52.
23. Scharf SM. Ventilatory Support in Cardiac Failure. in Kveton V, Dantzker D (eds), The Critically Ill Cardiac Patient, J.B. Lippencott, New York, 1996, pp. 29 - 46.
24. Scharf SM. Hypotension in a mechanically ventilated asthmatic. In Pinsky MR (ed). Critical Care Management Case Studies: Tricks and Traps. W.B. Saunders Co. 1997; pp 63 - 67.
25. Scharf SM. The normal adult pulmonary circulation. In Baum G, Wolinsky E, Karlinsky J (eds). Textbook of pulmonary diseases. 6th Ed. Little Brown Co., Boston, 1997; pp 1257-1271.
26. Scharf SM. Pulmonary Heart Disease. In Baum G, Wolinsky E, Karlinsky J (eds). Textbook of pulmonary diseases. 6th Ed. Little Brown Co., Boston, 1997; pp 1311- 1325.
27. Scharf SM. Mechanical Cardiopulmonary interactions in critical care. In Dantzker DR and Scharf SM (eds). Cardiopulmonary Critical Care 3rd ed. WB Saunders, Philadelphia, 1998, pp 75 - 92.
28. Multz A, Scharf SM. Pharmacologic and ventilatory support of the circulation in critically ill patients. In Dantzker DR and Scharf SM (eds). Cardiopulmonary Critical Care 3rd ed. WB Saunders, Philadelphia, 1998, pp 329 - 356.
29. Silverman R, Scharf SM. Pulmonary Function Testing in the Emergency Department. In Brenner BE (ed), Emergency Asthma. Marcel Dekker, New York, 1999, pp 233 - 252.
30. Scharf SM, Greenberg HE. Control of ventilation in congestive heart failure. In Altus, MD and Kawakami Y(eds). Control of Breathing in Health and Disease. In Lung Biology in Health and Disease, series editor C. Lenfant. Marcel Dekker Inc, New York, 1999, pp. 551 - 579.
31. Scharf SM. Effects of continuous positive airway pressure in animal models of congestive heart failure. In Bradley TD and Floras J “Sleep Apnea. Implications in cardiovascular and cerebrovascular disease.” Marcel Dekker, Inc., New York 2000, pp.435 - 460.
32. Scharf SM. Cardiovascular effects of emphysema. In Ginsberg ME and Argenziano M (eds). Lung Volume Reduction Surgery, Humana Press, Totowa, NJ, 2001, pp. 29 – 56.
33. Scharf SM, Pinsky MR, Magder S. Heart-Lung Interactions: An Overview. In Scharf SM, Pinsky MR, Magder S (esd). Respiratory-Circulatory Interactions in Health and Disease. Marcel Dekker, Inc., New York, 2001, pp. 1– 8.
34. Magder S and Scharf SM. Venous Return. In Scharf SM, Pinsky MR, Magder S (esd). Respiratory-Circulatory Interactions in Health and Disease. Marcel Dekker, Inc., New York, 2001, pp.93 = 112.
35. Scharf SM. Ventilatory Support in the Failing Heart. In Scharf SM, Pinsky MR, Magder S (esd). Respiratory-Circulatory Interactions in Health and Disease. Marcel Dekker, Inc., New York, 2001, pp. 519-550.
36. Scharf SM, Chen L, Greenberg H, O’Donnell CP. Cardiovascular responses to obstructive apneas: Lessons from Animal Models. In Scharf SM, Pinsky MR, Magder S (ed). Respiratory-Circulatory Interactions in Health and Disease. Marcel Dekker, Inc., New York, 2001, pp. 613 – 640.
37. Podszus TE, Feddersen CO, Scharf SM. Sleep apnea and right ventricular function. In Scharf SM, Pinsky MR, Magder S (eds). Respiratory-Circulatory Interactions in Health and Disease. Marcel Dekker, Inc., New York, 2001, pp. 641-650.
38. Scharf SM, Sica AS, Heart-Lung Interactions. In Haddad GG, Abman SH, Chernick V (eds). Basic mechanisms of pediatric respiratory disease – 2nd edition. BC Dekker Inc, Hamilton, 2002; pp. 234 – 249.
39. Scharf SM, Weg I, Keller C. Cardiovascular Effects of Lung Volume Reduction and Emphysema. In Reilly J, Sugarbaker D, Fessler H (eds), Lung Volume Reduction Surgery; Marcel Dekker Inc., New York, 2003; pp. 65 – 98.
40. Sarmiento K, Scharf SM. Pulmonary Hypertension and Obstructive Sleep Apnea. In Peacock A, Naeije R, Rubin L (eds). Pulmonary Circulation; Hodder Arnold Press, London, UK, 2011; pp 472 – 478.
41. Greenberg H, Lakticova V, Scharf SM. Pathophysiology, Clinical Features and Evaluation of Obstructive Sleep Apnea. Kryger MH, Roth T, Dement WC, et al. Principles and Practice of Sleep Medicine, 6th ed. 2016: Chapter 114: 1110 – 1124. Elsevier, Philadelphia, PA.
Publications – Abstracts/Proceedings
.
A1. Scharf SM, Bromberger-Barnea B. Factors affecting coronary venous partition. Fed Proc. 1970;29:654.
A2. Scharf SM, Bromberger-Bromberger-Barnea JB. Effects of changes in coronary blood flow and coronary sinus pressure on cardiac contractility. Fed Proc. 1972; 31:329.
A3. Scharf SM, Bromberger-Barnea B. Cardiac effects of hypoxia and carbon monoxide-induced hypoxia. The Physiologist 1972; 15:257.
A4. Scharf SM, Bromberger-Barnea B. Cardiac effects of hypoxic and co-induced hypoxia at constant coronary blood flow. Fed Proc. 1973; 32:387.
A5. Traystman RJ, Scharf SM, Stene JK, Permutt S. Increased venous return in hypoxia. The Physiologist 1973; 16:472.
A6. Scharf SM, Stene JK, Traystman RJ. Effects of alpha adrenergic blockade on hemodynamic responses to arterial hypoxia. Circulation 1973; 7 & 8:iv-2.
A7. Sylvester J, Scharf SM, Gilbert R, Fitzgerald R. Hemodynamics and arterial catecholamines during hypoxic hypoxia and carbon monoxide induced hypoxia. Fed Proc. 1975; 34:420.
A8. Scharf SM, Caldini P. Cardiovascular effects of increasing airway pressure. Fed Proc. 1976; 35:399.
A9. Green LH, Scharf SM, Saunders NA, Ingram RH, Grossman W. The effects of respiratory loading on left ventricular hemodynamics. Clin Res. 1977; 25:417A.
A10. Scharf SM, Feldman NT, Goldman MD, Ingram RH. Mechanism producing inspiratory upper airway obstruction during electrophrenic respiration and ventilation with an iron lung. Am Rev Resp Dis. 1977; 115:160.
A11. Scharf SM, Brown R, Saunders NA, Green LH, Ingram RH. Changes in left ventricular dimensions with PEEP. Fed Proc. 1978; 37:824.
A12. Scharf SM, Brown R, Tow DE, Parisi AF. Changes in ventricular volume with high lung volume and negative pleural pressure. Am Rev Resp Dis. 1978; 117:174.
A13. Tow DE, Scharf SM, Brown R, Parisi AF. Quantitative radionuclide imaging demonstrating changes in left ventricular function with negative intrathoracic pressure at high lung volume. Proc World Fed Nucl Med & Biol. 1978; 2:140.
A14. Scharf SM, Brown R, Saunders NA, Green LH. Hemodynamic effects of inspiration. Am Rev Resp Dis. 1979; 119:116.
A15. Brown R, Scharf SM, Ingram RH. Non-homogeneous alveolar pressure swings in the presence of airway closure. Am Rev Resp Dis. 1979; 119:292.
A16. Slutsky AS, Scharf SM, Brown R, Ingram RH. Effects of oleic acid induced pulmonary edema on the lungs and chest wall mechanics in dogs. Am Rev Resp Dis. 1979; 119:388.
A17. Strohl K, Scharf SM, Brown R, Ingram RH. Mechanism of inspiratory decreases in aortic flow with induced bronchospasm. Fed Proc. 1979; 38:1268.
A18. Scharf SM, Brown R. Factors influencing aortic pressure and flow during mechanical positive pressure ventilation (V). The Physiologist 1979; 22:111.
A19. Urmey W, Scharf SM, Song P, Brown R, Carlson D. The effects of interstitial fluid (kerosene) on lung mechanics in the rat. Fed Proc. 1980; 39:485.
A20. Scharf SM, Bianco J, Tow DE, Brown R. Effect of large negative intrathoracic pressure on left ventricular performance in patients with coronary artery disease (CAD). Am Rev Resp Dis. 1980; 121:186.
A21. Fanta CH, Leith DE, Brown R, Scharf SM, Song P, Ingram RH. Ventilatory muscle endurance training in chronic obstructive pulmonary disease. Am Rev Resp Dis. 1980; 121:133.
A22. Brown R, Scharf SM, Ingram RH. Non-homogeneous alveolar pressure swings in the presence of airway closure: influence of activity of different respiratory muscles. Am Rev Resp Dis. 1980; 121:320.
A23. Scharf SM, Heimer D, Weiner T, Gardsbane A, Goldstein J. Kerosene induced changes in the quasistatic pressure volume (PV) curve of rat lungs. Is J Med Sci. 1981; 17:70.
A24. Scharf SM, Heimer D, Goldstein J. The effect of kerosene aspiration on rat lungs. Am Rev Resp Dis. 1981; 123:124.
A25. Scharf SM, Gardsbane A. Response of dogs to inspiratory resistive loading (IL). Am Rev Resp Dis. 1982; 125:221.
A26. Tal A, Abiram M, Bar-Ziv Y, Scharf SM. Effect on lung function in asymptomatic children years after kerosene aspiration (Hebrew). Proc Is Soc for Clin Ped. 1982:23.
A27. Bark H, Levy R, Scharf SM. Fatigability of the canine diaphragm. The Physiologist 1982; 25:211.
A28. Scharf SM, Prinsloo I. Pulmonary mechanics in dogs given different doses of intratracheal kerosene. Is J Med Sci. 1983; 19:102.
A29. Bark H, Scharf SM. Diaphragm fatigue in the dog caused by phrenic nerve stimulation at different frequencies and train duration. Is J Med Sci. 1983; 19:98.
A30. Scharf SM, Bark H. Function of the canine diaphragm with hypovolemia. Am Rev Resp Dis. 1983: 127:257.
A31. Bark H, Scharf SM. Mechanical and electrical responses of the canine diaphragm to phrenic nerve stimulation. Am Rev Resp Dis. 1983; 127:252.
A32. Bar-Ziv J, Sofer S, Scharf SM. Pulmonary edema following relief of upper airway obstruction. Ann Rad. 1983. 26:257.
A33. Bar-Ziv J, Sofer S, Scharf SM. Pulmonary edema following relief of upper airway obstruction. Ped Rad 1983;13:178.
A34. Bark H, Scharf SM. Neural and muscular components of diaphragm fatigue in the dog caused by phrenic nerve pacing. Meeting of Israel Physiological and Pharmacological Society. March, 1983.
A35. Scharf SM, Heimer D, Walters M. Bronchial challenge with isocapnic hyperventilation and histamine in dyspneic patients. Medax Israel Medical Week. February, 1983, p 37.
A36. Tarasiuk A, Scharf SM. Changes in the muscles of inspiration during chronic resistive loading. Proc of 9th International Congress of Physical Medicine and Rehabilitation 1984:39.
A37. Bark H, Scharf SM. Blood flow limitation to the diaphragm. Proc of 9th International Congress of Physical Medicine and Rehabilitation. 1984:45.
A38. Baer R, Bark H, Einhorn S, Scharf SM. Influence of hemorrhagic shock on blood flow of the lactate production by the canine diaphragm. Am Rev Resp Dis. 1985; 131(4):A330.
A39. Schwartztein R, Leith D, Scharf SM, Brown R. C02 response curves in quadriplegia. Am Rev Resp Dis. 1985; 131(4):A337.
A40. Kariya S, Scharf SM, Brown R. Effect of aminophyllin on blood flow to the canine diaphragm. Am Rev Resp Dis. 1985; 131(4):A338.
A41. O'B Woods B, Scharf SM, Dilts CA, Weeks G, Josa M, Khuri SF, Tow DE. Left ventricular regional function in the early post coronary artery bypass period. Clin Res. 1985; 33:750A.
A42. Scharf SM, Warner KG, Josa M, Brown R, Khuri S. Load tolerance of the right ventricle (RV): Effect of increased aortic pressure (Pao). Am Rev Resp Dis. 1986; 133(Suppl):A304.
A43. Pope AR, Scharf SM, Brown R. Diaphragm metabolism during repetitive phrenic nerve stimulation in a canine model of diaphragm fatigue. Am Rev Resp Dis. 1986; 133(Suppl):A250.
A44. Schwartzstein R, Leith D, Scharf SM, Brown R. Ventilatory muscle training: targeted vs untargeted breathing. Am Rev Resp Dis. 1986; 133(suppl):A191.
A45. Warner KG, Scharf SM, Brown R, Khuri SF. Role of the pericardium in determining load tolerance of the right ventricle. Circulation 1986; 74: II-442.
A46. Nichols DG, Scharf SM, Traystman RJ, Robotham JL. Correlation of flow measured in the left phrenic artery with left and right hemidiaphragmatic blood flow. Am Rev Resp Dis. 1987; 135 (Suppl):A331.
A47. Scharf SM, Brown R, Lavigne N. Relationship between esophageal and regional pericardial pressures during respiratory maneuvers in dogs. Am Rev Resp Dis. 1987; 135 (Suppl):A116.
A48. Scharf SM, Brown R, Tow DE, Dilts C, McIntyre K. Effect of posture on hemodynamic response to the Mueller maneuver. Am Res Resp Dis. 1987; 135 (Suppl):A114.
A49. Scharf SM, Brown R, Warner KG, Khuri S. Respiratory changes in left ventricular (LV) configuration during negative and positive pressure ventilation. Am Rev Resp Dis 1988; 137(Suppl)A292.
A50. Brown R, Sakarati M, Tun C, Peterson JC, Scharf SM. Phrenic nerve pacer output is temperature dependent. Am Rev Resp Dis 1988;137(Suppl):383.
A51. Khilnani S, Scharf SM, Graver M, Rao PS, Iosif H, Balaban K. Effects of inspiratory loading (IL) on left ventricular blood flow and oxygen utilization. Am Rev Resp Dis. 1990; 141:A65.
A52. Scharf SM, Graver M, Khilnani S, Iosif H, Balaban K. Phasic effects of inspiratory loading (IL) on left ventricular (LV) afterload and blood flow (CBF). Am Rev Resp Dis, 1990; 141:A65.
A53. Scharf SM, Graver LM, Balaban K, Knaupp W. Periodic apneas cause myocardial ischemia in the presence of coronary stenosis. Am Rev Resp Dis, 1991; 143:A609.
A54. Rao RS, Balaban K, Graver LM, Urivetsky M, Scharf SM. Effect of bicarbonate on myocardial function: a new hypothesis. Am Rev Resp Dis 1991; 143:A245.
A55. Garshick E, Tosteson TD, Zaltzman M, Iosif G, Scharf SM. Hypertension, obstructive sleep apnea, and symptoms of disordered sleep in a community based slep center. Am Rev Resp Dis; 1992 145:A867.
A56. Garshick E, Scharf SM. Symptoms and missing information in a mail survey of sleep disordered breathing. Am Rev Resp Dis 1992; 145:A866.
A57. Salejee I, Tarasiuk A, Scharf SM. Cardiac effects of chronic upper airways obstruction in rats. Am Rev Resp Dis 1992; 145: A71.
A58. Greenberg HE, Scharf SM. Impairment of inspiratory load compensation in obstructive sleep apnea (OSA). Am Rev Resp Dis 1992; 145: A633.
A59. Tarasiuk A, Scharf SM. Venous return in obstructive apneas. Proc of Australian Society of sleep medicine international meetings, 1992. p 31.
A60. Bloch H, Silverman R, Mancherje N, Arsove P, Grant S, Jagminas L, Scharf SM. Magnesium is a useful adjunct to standard therapy for acute severe asthma. Chest 1992; 102: 83S.
A61. Genovese J, Moskowitz M, Tarasiuk A, Belmonte A, Graver LM, Scharf SM. Effects of CPAP on cardiac output in normal and hypervolemic unanesthetized pigs. Am Rev Resp Dis 1993, 147:A609.
A62. Greenberg H, Tarasiuk A, Scharf SM. Effect of chronic resistive loading on ventilatory control in rats. Am Rev Resp Dis 1993, 147:A162.
A63. Tarasiuk A, Scharf SM. Effects of periodic central and obstructive apneas on hemodynamics. Am Rev Resp Dis 1993, 147:A614.
A64. Pokala P, Llanera M, Sherwook J, Scharf SM, Steinberg H. Erythropoietin response in subjects with obstructive sleep apnea syndrome. Am Rev Resp Dis 1993, 147:A1018.
A65. Scharf SM, Kupferman M, Kane N, Tarasiuk A, Greenberg H. Weight gain, food intake and oxygen consumption in rats with upper airway obstruction. Am J Resp Crit Care Med 1994, 149: A799.
A66. Rao R, Greenberg H, Kane N, Scharf SM. Effect of chronic resistive loading on hypoxic ventilatory sensitivity. Am J Resp Crit Care Med 1994, 149: A256.
A67. Rao R, Greenberg H, Kane N, Scharf SM. γ-Aminobutyric acid mediates suppression of CO2 sensitivity during chronic resistive loading. Am J Resp Crit Care Med 1994, 149:A799.
A68. Huberfeld S, Genovese J, Tarasiuk A, Scharf SM. Effects of CPAP on pericardial pressure, transmural left ventricular pressures and respiratory mechanics in hypervolemic unanesthetized pigs. Am J Resp Crit Care Med 1994, 149:A1062.
A69. Schwartz M, Scharf SM, Greenberg H. The effect of nasal continuous positive airway pressure therapy on hypertension in patients with obstructive sleep apnea. Am J Resp Crit Care Med 1994, 149:A493.
A70. Tarasiuk A, Sofer S, Huperfeld S, Scharf SM. Hemodynamic effects following injection of scorpion venom. Am J Resp Crit Care Med 1994, 149:A1064.
A71. Genovese J, Moskowitz M, Tarasiuk A, Huberfeld S, Palazzo R, Scharf SM. Effects of CPAP on cardiac output in pigs with pacing induced cardiomyopathy. Am J Resp Crit Care Med 1994, 149:A1062.
A72. Luchsinger J, Steinberg H, Scharf SM. Pulmonary rehabilitation for working chronic obstructive pulmonary disease patients. Am Rev Resp Crit Care Med 1994, 149:A596.
A73. Cohen R, Huberfeld S, Genovese J, Scharf SM. Coronary blood flow and myocardial function after nitric oxide synthetase inhibition in endotoxemic dogs. Am J Resp Crit Care Med 1995; 151: A16.
A74. Huberfeld S, Genovese J, Patel U, Scharf SM. Factors associated with increased cardiac output with CPAP in hypervolemic pigs. Am J Resp Crit Care Med 1995; 151: A706.
A75. Weiss JR, Greenberg H, Papp L, Scharf SM. Effects of sertraline on dyspnea and respiratory control in patients with COPD. Am J Resp Crit Care Med 1995; 151: A464.
A76. Rao RS, Greenberg H, Sica A, Siddiqi Z, Scharf SM. Effect of chronic resistive airway loading on central ventilatory control. Am J Resp Crit Care Med 1995; 151: A408.
A77. Graham CJ, Rao R, Sica AS, Greenberg HE, Scharf SM. Effect of intrauterine cocaine exposure on postnatal ventilatory control. Am J Resp Crit Care Med 1995; 151: A635.
A78. Rao R, Greenberg HE, Sica AL, Scharf SM. Respiratory center GABA-A activity contributes to ventilatory suppression during chronic resistive loading. Am J Resp Crit Care Med 1996; 153: A156.
A79. Greenberg H, Scharf M, Sica A, Cook J, Cox E, W Mendelson, SM Scharf. Effect of 3-carbo-t-butoxy-β-carboline (βCCT), a selective benzodiazepine1 receptor antagonist on control of ventilation. Am J Resp Crit Care Med 1996; 153: A158.
A80. Chen L, Scharf SM. Comparison of hemodynamic effects of periodic obstructive and “central” apneas in pigs. Am J Resp Crit Care Med 1996; 153: A200.
A81. Chen L, Scharf SM. Influence of hypoxia and hypercapnia on the cardiovascular response to periodic apneas in sedated pigs. Am J Resp Crit Care Med 1996; 153: A406.
A82. Sofer S, Cohen RO, Colon A, Shapir Y, Chen L, Scharf SM. Respiratory and hemodynamic effects of scorpion venom in pigs. Am J Resp Crit Care Med 1996; 153: A 467.
A83. Cohen RI, Chen L, Colon A, Shapir Y, Scharf SM. The myocardial effects of nitric oxide inhibition in endotoxemic pigs. Am J Resp Crit Care Med 1996; 153: A832.
A84. Silverman R, Gallegher EJ, Scharf SM. Lack of agreement between FEV1 and PEFR in acute asthma. Am J Resp Crit Care Med 1996; 153: A771.
A85. Graham CJ, Rossoff L, McKeon K, Graver LM, Scharf SM. Tidal work of breathing following lung volume reduction surgery. Chest 1996; 174S: Proceedings of fall meeting of ACCP.
A86. Scharf SM, Graham CJ, McKeon K, Graver LM, Steinberg HN, Rossoff L. Determinants of maximum expiratory flow in patients undergoing lung volume reduction surgery. Chest 1996; 175S: Proceedings of fall meeting of ACCP.
A87. Weg IL, Rossoff L, McKeon K, Graver LM, Steinberg HN, Scharf SM. Development of pulmonary hypertension following lung volume reduction surgery. Chest 1996; 110, 57S: Proceedings of fall meeting of ACCP.
A88. Chen L and Scharf SM. Role of sympathoadrenal activation in acute hemodynamic response to simulated central apnea in sedated pigs. Am J Resp Crit Care Med 1997; 155: Proc of Spring Meeting of ATS
A89. Chen L and Scharf SM. Coronary Circulation during periodic obstructive apneas in sedated pigs. Am J Resp Crit Care Med 1997; 155: Proc of Spring Meeting of ATS
A90. Scharf SM, Ginsberg M, Thomoshow B, Jellin P, Rossoff L, McKeon K. Correlates of response to lung volume reduction surgery. Am J Resp Crit Care Med 1997; 155: Proc of Spring Meeting of ATS.
A91. Scharf SM, Ginsberg M, Thomoshow B, Jellin P. Serial follow-up in a cohort of patients undergoing lung volume reduction surgery. Am J Resp Crit Care Med 1997; 155: Proc of Spring Meeting of ATS
A92. Afulukwe IF, Cohen RI, Scharf SM. Non-specific nitric oxide synthase inhibition does not prevent the myocardial depression in endotoxemia. Am J Resp Crit Care Med 1998; 157: A105.
A93. Hassell Am, Bauer I, McKeon K, Rossoff L, Steinberg H, Scharf SM. Exercise limitation in lung volume reduction patients. Am J Resp Crit Care Med 1998; 157: A280.
A94. Chen L, Scharf SM. Cardiovascular response to periodic apneas in sedated pigs with congestive heart failure. Am J Resp Crit Care Med 1998; 157: A775.
A95. Slamowitz D, Chen L, Scharf SM. Effects of vagotomy on cardiovascular response to periodic apneas. Am J Resp Crit Care Med 1998; 157: A775.
A96. Hassel AM, Cohen R, Davies A, Lamet S, Marini C, Chen L, Scharf S. Comparison of the effect of nitric oxide synthase inhibitors on blood flow in pigs. Am J Resp Crit Care Med 1999; 159: A611.
A97. Mishra A, Schiff MJ, Fein AM, Geinsilver SH, Scharf SM. Descriptive analysis of asthma in a large health system. Am J Resp Crit Care Med 1999; 159: A132.
A98. Mishra A, Schiff MJ, Fein AM, Feinsilver SH, Scharf SM. A comparison of demographics of asthma hospital discharges in a large health system with national hospital discharges. Am J Resp Crit Care Med 1999; 159: A135.
A99. Greenberg HE, Sica A, Ruggiero D, Scharf SM. Expression of c-fos in the rat brainstem after chronic intermittent hypoxia. Am J Resp Crit Care Med 1999; 159: A221.
A100. Chen L, Tere R, Scharf SM, Aortic depressor nerve mediates pressor response to obstructive apnea in sedated pigs. Am J Resp Crit Care Med 1999; 159: A423.
A101. Marzouk K, Cohen R, Levine M, Berkoski P, O'Donell CP, Polotsky VY, Scharf SM, Correlates Of Resting Energy O2 Consumption (RO2) In Severe Emphysema. Am J Resp Crit Care Med 2000; 161: A232
A102. Oo MK, Chen L, Scharf SM. Pulmonary Hemodynamic Changes With Apneas In Sedated Pigs. Am J Resp Crit Care Med 2000; 161: A549
A103. Mishra A, Fein AM, Schenck ML, Feinsilver SH, Scharf SM. Diurnal Patterns Of Asthma Admissions. Am J Resp Crit Care Med 2000; 161: A624
A104. Benoff B, Greenberg H, Sica A, Scharf S. Chronic Intermittent Hypoxia (CIH) In Rats Blunts The Pressor Response To NO Synthase (NOS) Inhibition. Am J Resp Crit Care Med 2000; 161: A629.
A105. Iqbal M, Keller C, Criner G, Fessler H, Berkoski P, Scharf S. Pulmonary Hemodynamics In Patients With Severe Emphysema. Am J Resp Crit Care Med 2000; 161: A817.
A106. Iqbal M, Cohen RI, Marzouk KA, Scharf SM, Liu SF. Glutathione Peroxidase Activity Correlates With Myocardial Depression In Rat Model Of Endotoxemia. Am J Resp Crit Care Med 2000; 161: A885.
A107. Mishra A, Scharf SM, Fein AM. Increase in asthma hospitalizations in the elderly. Am J Resp Crit Care Med 2000; 161: 440S.
A108. Mishra A, Scharf SM, Feinsilver SH, Fein AM. Influence of age on resource utilization in asthma hospitalization. Chest 2001; 120: 148S.
A109. Fessler HE, S Scharf, S Permutt. Improvement in FEV1 and FVC after LVRS: Application of a Physiologic Model. Am J Resp Crit Care Med 2001;163: A703.
A110. Cohen RJ, J Zhao, K Marzouk, SM Scharf. Soluble TNF receptor levels are elevated in non smoking weight stable emphysema. Am J Resp Crit Care Med 2001; 163: A346.
A111. Stoica GS, J Zhao, R Cohen, SM Scharf. Oxidative stress and myocardial contraction in rats exposed to intermittent hypoxia (IH). Am J Resp Crit Care Med 2001; 163: A488.
A112. Stoica GS, SM Scharf. Resting work of breathing (WB) in patients with severe emphysema (EMP). Am J Resp Crit Care Med 2001; 163: A691.
A113. Ramsdell JW, SM Scharf, MJ Renvall, AL Ries. Predictors of Body Mass Index in Patients with Moderate to Severe Emphysema. Am J Resp Crit Care Med. 2003; 167: A236.
A114. Nazarian JTM, S Scharf, E Monaghan. Weaning from Mechanical Ventilation in a Chronic Ventilator Unit. Am J Resp Crit Care Med 2003; 167: A459.
A115. Scharf SM, Northam DM, Seiden L. Racial differences in sleep apnea severity in a University Based Sleep Disorders Center. Sleep 2003; 26: A220.
A116. Mastronarde JG, Wise RA, Scharf SM, Shade DM, Olopade CO. Sleep quality in asthma: results of a large prospective clinical trial. Chest 2004: 126 (4); 906S.
A117. Fisher MR, Hassoun P, Criner G, Scharf S, Fessler HE. Accuracy of Doppler Echocardiography (DE) for pulmonary hypertension in the National Emphysema Treatment Trial (NETT). Am J Resp Crit Care Med 2004; 169: A178.
A118. DeMore JP, Seiden L, Carter-Pokras O, Scharf SM. Long-term CPAP compliance in a racially diverse population. Am J Resp Crit Care Med 2004; A690.
A119. Finkelstein J, Shaya FT, Arora M, Joshi A, Samant N, Scharf SM. Automated survey collector (ASC): A universal Platform for interactive collection of clinical data. The 8th World Multi-Conference on Systemics, Cybernetics and Informatatics, July 18 – 21, 2004 – Orlando, FL.
A120. Whitting, M, Scharf SM. Racial Differences in Room-Air Pulse Oximetry. Presented at Society for Academic Emergency Medicine Mid-Atlantic Regional Meeting October 1 in the Georgetown Conference Center.
A121. Abdelhady H, Flores R. Tan H, Hasday J, Fitzgerald T, Scharf SM. Infliximab treatment for Chronic Obstructive Pulmonary Disease (COPD) – A Pilot Study. Am J Resp Crit Care Med 2005; A133.
A122. Patel SA, Rogers RM, Coxson HO, Scharf SM, Wise RA, Slivka WA, Luketich JD, Hogg JD, Sciurba FX. The relationship between lung mechanics and quantitative radiographic emphysema. Am J Resp Crit Care Med 2005; A293.
A123. Shaya FT, El Khoury AC, Mullins CD, Scharf SM. Cost and resource utilization in a Medicaid COPD population. Am J Resp Crit Care Med 2005; A645.
A124. Scharf SM, Chen L, Einbinder E, Hasday J, Balke CW. Oxidative Stress (OS) and Left Ventricular (LV) Function in Chronic Intermittent Hypoxia (CIH). Am J Resp Crit Care Med 2005; A879.
A125. Welch K, Scharf SM. Construct Validity for Health Utilities Indices in a Sleep Disorders Center. Sleep 2005; 28: A183, Abs. 541.
A126. Scharf SM, Tubman A, Smale P. Prevalence of concomitant sleep disorders in patients with obstructive sleep apnea (OSA). Sleep 2005; 28: A157, Abs 462.
A127. Tan H, Witting M, Scharf SM, Error analysis of spirometry performed in a research setting. Proc of the Am Thoracic Soc. (abstracts issue) 2006, 3; A134.
A128. Zhang J, Scharf SM, Gan TX, Blaustein MP, Hasday J, Chen L. Cardiovascular Effects of Chronic Intermittent Hypoxia in Mice. Presented at Spring 2006 meeting of Experimental Biology, San Fransisco, 2006.
A128. Ramagopal. M, Blaisdell CJ, Scharf SM. Asthma and Obstructive Sleep Apnea in snoring children. Proc of the Am Thoracic Soc. (abstracts issue) 2006, 3; A556.
A129. Chen L, Zhang J, Gan XT, Zhang Q, Hasday J, Karmazyn M, Scharf SM. Chronic intermittent hypoxia upregulates myocardial expression of sodium hydrogen exchanger-1 in rats. Proc of the Am Thoracic Soc. (abstracts issue) 2006, 3; A222.
A130. Giardino ND, Curtis JL, Fan V,m Naunheim K, Criner G, Make B, Wise R, Fishman A, Weinmann G, Washko G, Sciurba F, Scharf S. Maladaptive beliefs mediate of the association between anxiety and impaired exercise performance. AJRCCM. 2007; 175: A 548.
A131. Galezka M, Britt EJ, Pierson R, Hasday J, Scharf S, Griffith B, Todd N, Iacono AT. Does the native lung in single lung transplant recipients with COPD affect post-transplant lung function? AJRCCM 2007; 175; A765.
A132. Ramagopal M, Mehta A, Blaisdell CJ, Mudd KE, Wolf JS, Taylor RJ, Scharf SM Does asthma contribute to the severity of OSA in children? AJRCCM 2007; 175; A277.
A133. Verceles AC, Patel K, Diaz-Abad M, Shanholz C, Scharf SM. Diurnal variations of ambient light in a critical care unit. Sleep 2008 (abstract supplement); 31: A49.
A134. Geiger-Brown J, Rogers V, Tinkoff AM, Kane R, Scharf S. Sleep, sleepiness and neurocognition in 12-hour nurses: preliminary results. Sleep 2008 (abstract supplement); 31: A115.
A135. Alattar M, Scharf SM. Case series of effect of bilevel positive airway pressure ventilation on opioid induced central sleep apnea in patients with chronic pain. Sleep 2008 (abstract supplement); 31: A166.
A136. Scharf SM. Williams AL, Chen L, Wu J. Short term chronic intermittent hypoxia leads to cardiac dysfunction and oxidative stress. Sleep 2008 (abstract supplement); 31: A182.
A137. Chen L, Zhang J, Wu J, Blaustein MP, Scharf SM. Time course of blood pressure, heart rate and locomor activity in mice with chronic intermittent hypoxia. Sleep 2008 (abstract supplement); 31: A211.
A138. Patel K, Scharf S, Verceles A, Griffith B. Sleep Disturbances in end-stage lung disease. Sleep 2008 (abstract supplement); 31: A293.
A139. Zhang J, Scharf SM, Gan XT, Blaustein MP, Karmazyn M, and Chen L. Cardiovascular effects of chronic intermittent hypoxia in mice. FASEB J, 20(4 pt 1): A791
A140. Williams A, Chen L, Wu J, Scharf SM. Allopurinol ameliorates Cardiac Damage and Oxidant Stress of Chronic Intermittent Hypoxia. Sleep 2009; 32 (abstract): A29.
A141. Geiger-Brown J, Rogers V, Scharf S, Trinkoff A. Short total sleep time in 12-hour shift nurses: slow unwinding, circadian disruption, or time allocated to sleep? Sleep 2009; 32 (abstract): A138.
A142. Chen L, Zhang J, Wu J, Gan TX, Karmazyn M, Philipson KD, Blaustein MP, Scharf SM. Cardiac NA/CA Exchanger-1 mediates cardiac injury in mice with chronic intermittent hypoxia. Sleep 2009; 32 (abstract): A 223.
A143. Shaya FT, Lin P, Alijawadi MH, Scharf SM. Elevated economic burden in obstructive lung disease patients with concomitant sleep apnea. Sleep 2009; 32 (abstract): A324.
A144. Maimon, N, Simon-Tuval T, Tarasiuk A, Reuveni H, Bernhard-Scharf B, Scharf SM, Sleep disturbances and health-related quality of life in patients with COPD. Am J Resp and Crit Care Med, abstracts of ATS meeting Spring, 2010.
A145. Geiger-Brown J, Rogers V, Bausell R, Trinkoff A, Kane R, Scharf SM. Lapses of attention, and reaction times in sleep-deprived nurses working successive 12-hour shifts. Sleep 2010; 33: Abstract supplement: A102.
A146. Dotan-Greenberg S, Yan X, Scharf SM, Shaya FT. The economic burden of obstructive sleep apnea in the components levels of the metabolic syndrome. Presented at ISPOR Israeli meeting, 2011, March 30.
A147. Koldobskiy D, Diaz-Abad M, Patel S, Brown J, Scharf SM, Verceles A. Circadian Rhythm In The Chronically Ventilated Patient. ATS Spring Meeting 2012, San Francisco, CA
A148. Romem A, Iacono A, McIlmoyle E, Patel K, Verceles A, Scharf SM. Sleep Disturbances in End-Stage Lung Disease – a descriptive study. ATS Spring Meeting 2012. San Francisco, CA.
A149. Haque T, Scharf SM, Vossoughi J, Johnson A, Bell-Farrell W, Fitzgerald T. Resistance Measured By Airflow Perturbation Compared With Standard Measures. ATS Spring Meeting 2012. San Francisco, CA.
A150. Diaz-Abad M, Buczyner J, Venza B, Scharf SM, Russell JW. Poor sleep quality in patients with early Amyotrophic Lateral Sclerosis. ATS Spring Meeting 2012. San Francisco, CA.
A151. Santiago B, Scharf SM. Influence of missing question 8 on the Epworth Sleepiness Scale. Sleep (abstracts) 35; 2012; A428.
A152. M. Diaz-Abad, J.R.Buczyner, B.R. Venza, J.W. Russell, S.M. Scharf. Obstructive sleep apnea screening in patients with amyotrophic lateral sclerosis. Am J Crit Care Med (abstracts) 187; 2013; A2041.
A153. A. Romem, A. Romem, S.M. Scharf. Pain and its management at the end-of-life in patients with end-stage COPD admitted to an acute inpatient hospice: a comparative study. Am J Crit Care Med (abstracts) 187; 2013; A2504.
A154. K.F. Sarmiento, M. Cowan, D. King, S.M. Scharf. Effects of simvastatin in lipopolysaccharide-induced acute lung injury. Am J Crit Care Med (abstracts) 187; 2013; A4185.
A155: A. Romem, D. Koldobskiy, A. Romem, S.M. Scharf. Single Channel Photoplethysmography detection of sleep apnea. Sleep (abstracts) 36; 2013; A414.
A156: Korotinsky A, Diaz M, Scharf SM. Comparison of American Academy of Sleep Medicine (AASM) versus Medicare (CMS) scoring rules on AHI and eligibility for positive airway treatment. Sleep (abstracts) 37; 2014: A384.
A157. Assefa S, Nadkarni M, Syamaprasad S, Banks R, Scharf SM. Comparison of residual apnea-hypopnea indices (AHI) from adherence cards (AC) and a level four home sleep testing device. Sleep (abstracts); 37; 2014: A130.
A158. Assefa S, Diaz-Abad M, Scharf SM. Comparison of a simple sleep apnea screening device with standard in-lab polysomnography. Sleep (abstracts) 37; 2014: A132.
A159. Tom SE, Brandt N, Scharf SM, Geiger-Brown J, Guralnik JM, Hale LE, Stone K, Shah NA, LaCroix AZ. Patterns of sleep aid use in older American women. Sleep (abstracts) 37; 2014: A346.
A160. Tom SE, Scharf SM, Brandt N, Geiger-Brown J, Guralnik JM, Hale LE, Li W, Womak CR, Zaslavsky O, LaCroix AZ. Sleep aid use and physical function in older American Women. Sleep (abstracts) 37; 2014: A347.
A161. Short B, Scharf SM, Netzer G, Graves A, Shanholtz C. Ventilatory patterns in healthy subjects using high flow cannula nasal oxygen and continuous positive expiratory pressure (CPAP). Am J Resp Crit Care Med (abstracts); 2014; 189: abstract A1177.
A162. Geiger-Brown J, Scharf SM, Krachman SL, McEvoy C, Harnden S, Criner CJ. Sleep quality in patients with moderate to severe COPD. Am J Resp Crit Care Med (abstracts); 2014: 189: A5816.
A163 Reed RM, Dransfield M, Miller M, Mitchell B, Pavlovich M, Scharf S, Shuldiner AR, Netzer Gender and the health effects of environmental tobacco smoke: A study of the old order Amish. Spring meeting ATS.
A164 Zadi ZH, Scharf SM, Pae E, Chen L. Prenatal intermittent hypoxia affects body growth and cardiovascular function in rats. Sleep 2015; 38: A14
A165 Riar R, Al Fouzan W, Altememi N, Cohen L, Diaz-Abad M, Scharf SM. Efficacy of screening for obstructive sleep apnea in a general dental practice. Sleep 2015; 38: A198.
A166 Altememi N, Assefa S, Riar R, Diaz-Abad M, Scharf SM. Prediction of early CPAP compliance. Sleep 2015; 38: A200.
A167 MulliganMJ, Eberlein M, Dransfield M, Netzer G, Sanchez PG, Scharf SM, Sin D, Celli BR, Reed RM. Survival of lung transplant candidates with COPD: BODE reconsidered. Spring meetings, American Thoracic Society, San Francisco 2006.
A168 Johnson BP, Scharf SM, Westlake KP. Targeted memory reactivation during sleep, but not wake, improves sensorimotor, skill learning in healthy young adults. Spring meetings, World Congress for Neurorehabilitation (WCNR), Philadelphia, 2016.
Publications - Letter/Editorials/Other Brief Communications
1. Strohl KP, Scharf SM. Effect of intrathoracic pressure on left ventricular performance. Letter to the editor. New Eng J Med 1980; 302: 235 – 236. .
2. Scharf SM, Heimer D. The respiratory muscles - a new challenge. Editorial. Harefuah (Hebrew). 1984; 15:133-135.
3. Scharf SM. Left ventricular geometry during intermittent positive pressure ventilation in dogs. Editorial comment. J Crit Care 1987; 2:227-229.
4. Scharf SM, Steinberg HN, Greenberg H. Comment on Reflections on the Doctor's Anguish. Letter to the editor. Ann Int Med 118: 79 - 80, 1993. PMID: 8416173
5. Scharf SM, Huberfeld S, Genovese J, Tarasiuk A. Changes in pericardial pressure with CPAP - reply. Letter to the editor. Am J Resp Crit Care Med1995; 153: 1187-1188.
6. Papp L, Weiss JR, Greenberg HE, Rifkin A, Scharf SM, Gorman JM, Klein DF. Sertraline for chronic obstructive pulmonary disease and comorbid anxiety and mood disorders. Letter to the editor. Am J Psychiatry 1995; 152: 1531. PMID: 7573598
7. Dantzker DR, Scharf SM. Lung Volume Reduction Surgery. Editorial. New England Journal of Medicine 1996; 17: 1128-1129. PMID: 8598875
8. Scharf SM. Scorpion sting-The Inflammatory Dimension. Editorial in Crit Care Med 2002; 30:1669-1670. PMID: 12131006
9. Reed R, Scharf SM. Increased adverse events after percutaneous coronary intervention in patients with COPD. Letter to the editor. Chest 2012; 141: 828 – 829.
Major Invited Speeches
1977. American Thoracic Society, "Cardiovascular Effects of Positive End-Expiratory Pressure." San Francisco,
CA.
1978 American Heart Association, "Circulatory Effects of Positive End-Expiratory Pressure." Dallas, TX.
1985. International Congress on Right Ventricular Function, "Afterload and Right Ventricular Function." Paris,
France.
1985 World Congress of Intensive Care, "Muscles of Respiration in the Intensive Care Unit." Jerusalem, Israel.
1986. Annual Conference on Engineering in Medicine and Biology. Symposium on Heart-Lung Interaction via Pleural Space. "Mueller maneuver and left ventricular function in coronary disease." Baltimore, MD
1992 American College of Chest Physicians, "Cardiocirculatory consequences of obstructive sleep apnea."
1993 American College of Chest Physicians, "Sleep apnea for cardiologists."
1994. Spring Meeting of French language society of intensive care, "Right ventricular load tolerance: role of left ventricular function." Montreux, Switzerland. Published in Les Interaction Cardiopuolomonaires, Arnette 1994; Paris. PP 17 – 28.
1995. International symposium on cardiovascular effects of sleep-apnea syndrome. "Effects of decreased intrathoracic pressure on left ventricular function." Marburg, Germany.
1996. Spring Meeting of American Thoracic Society, Seattle, WA. "Effects of CPAP in congestive heart failure"
part of symposium on ventilatory support of the circulation.
1995. Invited speaker at NIH workshop on Lung Volume Reduction Surgery: "Possible cardiovascular effects of
LVRS." Sept, 1995 - Published in Am J Resp Crit Care Med 1996; 154: 1913-1918.
1996. 4th International symposium on Sleep and Respiration; Charlottsville, VA - “Effects of nasal CPAP in
experimental heart failure.”
1997. Spring Meeting of American Thoracic Society, New Orleans, LA - “Hemodynamic effects of CPAP in
normal and failing hearts.”
1996 Spring Meeting of American Thoracic Society, New Orleans, LA- "Ventilatory support of the failing heart."
1997. Workshop on Lung Volume Reduction Surgery - advisory committee for Massachusetts Blue Cross Blue Shield LVRS trial.
1998. ATS Conference on Clinical and Pathophysiological Interactions of Sleep Apnea and Heart Disease, Toronto: "Influence of Central and Obstructive Apnea on Hemodynamics in Animals"
1998. ATS International Meeting, San Francisco, CA: Featured Speaker in minisymposium on hemodynamic
consequences of sleep disordered breathing. "Coronary blood flow and myocardial oxygen demand in obstructive apneas in animals."
1997 World Intensive Care Congress, Ottowa, Canada. "Pathophysiology of congestive heart failure."
1999. NYS Association for Cardiac And Pulmonary Rehabilitation. “NIH National Emphysema Treatment Trial of Lung Volume Reduction Surgery.”
1999 Sixth International Symposium on Sleep and Respiration. “Afferent inputs in periodic apneas.”
2000. ATS International Meeting, San Diego, CA: Update on NIH National Emphysema Treatment Trial of Lung
Volume Reduction Surgery (NETT): Cardiovascular Substudy
2000. ATS International Meeting, Toronto, Canada: Cardiovascular effects of upper airway obstruction. In session
on Cardiopulmonary Interactions for the clinician (chaired session)
2001. Nassau-Suffolk Chapter of ALA: ACRC network trial: Safety of Inactivated Influenza Vaccine in Asthma. Part of Update in Pulmonary Diseases Yearly Symposium
2002. American Lung Association of Maryland: When do you treat sleep apnea, adult perspective. Part of Update in Pulmonary Diseases Yearly Symposium
2002 University of Maryland Medical Grand Rounds: Sleep Disordered Breathing
2002 Springfield Psychiatric Hospital Grand Rounds: Insomnia
2002 University of Maryland Annual Update in Internal Medicine: Sleep Apnea
2003. Mercy Medical Center Medical Grand Rounds: Sleep Disordered Breathing
2003 University of Maryland Dental School Grand Rounds: Sleep Disordered Breathing
2004. University of Maryland Annual Update in Internal Medicine: Sleep Disorders Overview
2003 Queen Anne’s County: Sleep Disordered Breathing
2004 Sleep Disordered Breathing. Workshop of FOOCUS meeting of Respiratory Therapists. April, 2004
2004 Prediction of CPAP Compliance. Greater Baltimore Medical Center – Sleep Medicine Associates Grand Rounds.
2004 Prediction of CPAP Compliance. Given at course “New Horizons in Sleep”, course organizer: SM Scharf
2004 Treatment of Insomnia: Univ of Maryland course: update in Internal Medicine
2004 Introduction to Sleep and Sleep Apnea; CHEP/ Dental Society Meeting, Ocean City, MD
2004 Introduction to Sleep and Sleep Apnea; Nat Institute of Aging
2004 Chronic Intermittent Hypoxia in rats: a model for sleep apnea; Nat Institutes of Aging
2004 State of MD Dental Society Meetings: Sleep Disordered Breathing for Dentists
2004 Laurel Hospital: Introduction to sleep disorders
2005. COPD and emphysema. Given at University of Maryland COPD and Alpha-1 Education Day.
2005 Infliximab in the Treatment of Chronic Obstructive Pulmonary Diseases. Given at the 3rd Annual Scientific Forum on Cancer and Other Tobacco-Related Diseases, June 3, 2005, University of Maryland.
2005 Is breathing bad for you? Given at ATS postgraduate course on Physiology and Critical Care
2006 Screening for Sleep Disordered Breathing in CHF; Seattle, WA, Heart Failure Society of America
2007 Clinical Screening for Obstructive Sleep Apnea. Delray Beach Medical Center, Delray Beach, Florida.
2008 Evaluation and Management of Excessive Daytime Sleepiness. Delray Beach Medical Center, Delray Beach, Florida.
2009 Clinical Aspects of Obstructive Sleep Apnea: Symposium on Sleep Apnea – Soroka Medical Center, Beersheba, Israel. Co-organizer of symposium.
2011 Sleep Disturbances in COPD – Maryland Sleep Society.
2012 “The correlation between chronic disease and insomnia.” Las Vegas, course in Wellness and Disease Management, Optimum Health Inc.
2012 “Insomnia”. To STEP program on sleep disorders, NIH, Bethesda, MD
2013 “Cardiopulmonary Effects of Sleep Apnea”. To NS-LIJ Medical System at Manhattan Eye and Ear Institute.
2013 “Cardiovascular effects of Sleep Apnea”. Shaarei Zedek Hospital, Jerusalem, Israel.
2016 “Emerging technologies in sleep medicine.“ Society for Respiratory Care – Mid-Atlantic Regional meeting
2016 ”Sleep Disturbances in COPD.” Dept of Pharmacology, Uniformed Services University of Health Sciences.
Divisional/Community/Other Lectures since 2002
2002- U of MD: Pulmonary Division Teaching Rounds (pulmonary fellows): Polysomnography
2002 U of MD: Endocrinology Grand Rounds: Sleep Disordered Breathing
2003 U of MD: ENT Grand Rounds: Sleep Disordered Breathing
2003 U of MD: Medical House Staff Noon Conference: Non-respiratory sleep disorders
2003 U of MD: Cardiology Grand Rounds: Sleep Disordered Breathing
2004 U of MD: Medical House Staff Noon Conference: Introduction to Sleep Medicine (given yearly)
2005 - U of MD: Medical House Staff Noon Conference: COPD, 2 part series.
2006 - U of MD: Medical House Staff Noon Conference: Sleep Disorders, 2 part series.
2011 Sleep disturbances in COPD – Pulmonary Grand Rounds
2009, 12: U of MD Mini Med School: “Sleep Disorders”
2013 Prince George’s County Medical Center: Introduction to Sleep Disorders.
2014 - U MD medical grand rounds: Sleep Apnea – who cares?
Addendum
Industry sponsored trials: S Scharf MD PhD (recent)
|Year |Sponsor |Title |Direct Costs (if |Role |
| | | |available) | |
|2006 - |Almirall |II. A RANDOMISED, DOUBLE-BLIND, PARALLEL GROUP, PLACEBO CONTROLLED, |Capitation |PI |
| | |MULTICENTRE CLINICAL TRIAL, TO ASSESS THE EFFICACY AND SAFETY OF 200 µG OF | | |
| | |THE ANTICHOLINERGIC LAS 34273 | | |
|2006 - |Boehringer Ingelheim |BIPI PROTOCOL 205.325: A RANDOMIZED, DOUBLE-BLIND. DOUBLE-DUMMY, PARALLEL |Capitation |PI |
| |Pharmaceuticals |GROUP TRIAL COMPARING 12 WEEKS TREATMENT WITH TIOTROPIUM INHALATION CAPSULES| | |
| | |18 MCG VIA THE HANDIHALER® ONCE DAILY TO COMBIVENT® INHALATION AEROSOL | | |
|2010 - 2012 |Forest Laboratories |Safety and efficacy of aclidinium bromide a long acting muscarinic agent in |Capitation |PI |
| | |COPD | | |
|2011 -2012 |Mediummune |A Prospective Observational Study to Evaluate Biomarkers in Acute |Capitation |PI |
| | |Exacerbations in Chronic Obstructive Pulmonary Disease | | |
|2011-2012 |Medimmmune |A Prospective Observational Study to Assess the Role of Selected Biomarkers |Capitation |PI |
| | |in Subjects Requiring Daily Medium- to High-dose Inhaled Corticosteroids for| | |
| | |Persistent Asthma | | |
|2012 - |Glaxo-Smith-Kline |SUMMIT trial |Capitation |PI |
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