Possible Side Effects of Cisplatin, Epirubicin, and 5 ...



Possible Side Effects of Cisplatin, Epirubicin, and 5-Fluorouracil (Table Version Date: November 7, 2013)

|COMMON, SOME MAY BE SERIOUS |

|In 100 people receiving Cisplatin, Epirubicin, and 5-Fluorouracil, more than 20 and up to 100 may have: |

|Diarrhea, nausea, vomiting, loss of appetite |

|Infection, especially when white blood cell count is low |

|Anemia which may cause tiredness, or may require blood transfusions |

|Bruising, bleeding |

|Kidney damage which may cause swelling, may require dialysis |

|Hearing loss including ringing in ears |

|Hair loss |

|Itching, rash, hot flashes |

|Sores in mouth which may cause difficulty swallowing |

|Tiredness |

|Fever |

|Absence of or irregular menstrual periods |

|Red urine |

|Redness, pain or peeling of palms and soles |

|Rash, increased risk of sunburn, itching |

|Difficulty swallowing |

|Heartburn |

|Headache |

|OCCASIONAL, SOME MAY BE SERIOUS |

|In 100 people receiving Cisplatin, Epirubicin, and 5-Fluorouracil, from 4 to 20 may have: |

|Allergic reaction which may cause rash, low blood pressure, wheezing, shortness of breath, swelling of the face or throat |

|Confusion |

|Difficulty with balance |

|Damage to the heart |

|Swelling, redness, pain or tissue damage at the site of the medication injection |

|Kidney damage which may require dialysis |

|Body aches |

|Dry or itchy eyes, blurred vision |

|Abnormal heartbeat |

|Chest pain |

|Blood clot |

|Belly pain |

|Internal bleeding which may cause black tarry stools |

|Infection, especially when white blood cell count is low |

|Cough, hoarseness |

|Abnormal eye movement, blurred vision, watering eyes |

|Discomfort from light |

|Swelling, redness, tingling and pain of hands and feet |

|Difficulty with balancing |

|RARE, AND SERIOUS |

|In 100 people receiving Cisplatin, Epirubicin, and 5-Fluorouracil, 3 or fewer may have: |

|Seizure |

|Heart failure which may cause shortness of breath, swelling of ankles, and tiredness |

|Damage to the heart which may cause shortness of breath |

|Cancer of bone marrow caused by chemotherapy |

|A new cancer resulting from treatment of earlier cancer |

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