INCOMPARTIBILITIES UN MEDICINAL FORMS
INCOMPARTIBILITIES UN MEDICINAL FORMS
1. Pharmacist got prescription for compounding mixtura with Codeini phosphatum and Natrii hydrocarbonas. Choose the process of their reaction:
A *Sedimentation of alkaloids
B Eutectic mix
C Immiscibility of ingredients
D Hydrolysis of cardiac glycosides
E Adsorbtion of medicinal matters
2. Pharmacist got prescription for compounding powders with Acidum ascorbinicum and Natrii hydrocarbonas. Choose the process of their reaction:
A *Dampening
B Acidification
C Adsorbtion
D Sedimentation
E Bundle
3. Pharmacist found incompartibility in the prescription:
Rp.: Sol. Collargoli 1 % - 10 ml
Sol. Adrenalini hydrochloridi 0,1 \% - 1 ml
M.D.S. Nose drops.
Choose the process of their reaction
A * Acidification
B Neutralization
C Sedimentation
D Hydrolysis
E Adsorbtion
4. Pharmacist got prescription:
Recipe: Extracti Belladonnae 0,015
Papaverini hydrochloridi 0,05
Carbonis activati 0,2
M. f. pulvis
D. t. d. №10
Signa: 1 powder 2 t. p. d.
Choose the reason of incompartibility:
A * Adsorbtion of medicinal matters
B Coagulation of colloidal system
C Oxidation-reduction reaction
D Acid-base interaction
E Eutectic mix
5. Pharmacist got prescription for compounding Decoctum foliorum Uvae ursi (foxberry) and Hexamethylentetraminum. Pharmacist put the stamp “Invalid prescription”. Choose the reason of incompartibility:
A * Sedimentation
B Eutectic mix
C Acidification
D Inwettability
E Insolubility
6. Pharmacist found incompartibility in the prescription with Kalii permanganas and Hydrogenii peroxydi. Choose the type of chemic reaction:
A * Oxidation-reduction
B Neutralization
C Ezchange
D Sedimentation
E Displacement
7. Pharmacist needs to compound the medicinal form: Rp.: Mentholi 0,1 Glycerini 10,0 M.D.S. Nose drops. Choose the reason of incompartibility:
A * Insolubility
B Bundle
C Adsorbtion
D Eutectic mix
E Coagulation
8. Pharmacist got prescription for compounding Decoctum foliorum Uvae ursi (foxberry) and Extractum Belladonnae. Choose the reason of incompartibility:
A * Sedimentation
B Hydrolysis
C Oxidation-reduction reaction
D Gassing
E Coagulation
9. Pharmacist got prescription for compounding mixtura with Natrii bromidum and Validolum. Choose the reason of incompartibility:
A * Immiscibility of ingredients
B Sedimentation
C Coagulation
D Oxidation-reduction reaction
E Adsorbtion
10. Pharmacist found incompartibility in the prescription:
Rp.: Mentholi 0,1 Natrii hydrocarbonatis Natrii tetraboratis ana 1,5 Aquae purificatae 100 ml M.D.S. 1 table spoon 2 t.p.d. What technological methods shoud be used to compound this medicinal form?
A * Adding stabilizator
B Fractional dissolution
C Solvent exchange
D Exchange of one component
E Exchange of the medicinal form
11. Pharmacist refused to compound medicinal form because of incompartibility of prescribed Collargolum and Dimedrolum. Choose the reason of incompartibility:
A * Coagulation
B Immiscibility
C Adsorbtion
D Bundle
E Eutectic mix
12. At compounding complex powders with Phenylii salicylas and Camphora liquid is formed. Choose the reason of incompartibility:
A * Eutectic mix
B Adsorbtion
C Allocation of crystallization water
D Hygroscopicity of the components
E Gassing
13. t compounding ointment with Oleum Ricini and Vaselinum pharmacist couldn’t get homogeneous system. Choose the reason of incompartibility:
A * Immiscibility of the components
B Limited solubility
C Allocation of crystallization water
D Coagulation
E Adsorbtion
14. Doctor prescribed Infusum Digitalis with Acidum hydrochloricum. Choose the reason of incompartibility:
A * Hydrolysis (without visible changes)
B Sedimentation
C Gassing
D Discoloration
E Change in odor
15. Pharmacist found incompartibility in prescription for compounding powders with Acidum ascorbinicum and Hexamethylentetraminum. Choose the process of their reaction:
A * Dampening
B Eutectic mix
C Immiscibility
D Adsorbtion
E Allocation of crystallization water
16. Pharmacist found physical incompartibility because of coagulation. Choose the medicines that have this process as a result of their interaction:
A * Dimedrolum and Collargolum
B Dimedrolum and Novocainum
C Dimedrolum and Natrii chloridum
D Dimedrolum and Diazolinum
E Dimedrolum and Glucosa
17. Pharmacist found physical incompartibility in prescription. Choose the medicines that form eutectic mix at their interaction:
A * Camphora and Mentholum
B Glucosa and Phenylii salicylas
C Streptocidum and Antipyrinum
D Acidum ascorbinicum and Natrii hydrocarbonas
E Bismuthi subnitras and Magnesii oxydum
18. Pharmacy got the prescription for compounding ear drops:
Rp.: Camphorae Mentholi ana 1,0 Olei Vaselini 25,0 Misce. Da. Signa. Ear drops. What difficulties would pharmacist have at compounding?
A * Eutectic mix
B Insolubility
C Coagulation
D Discoloration
E Adsorbtion
19. Pharmacist found incompartibility in prescription. Choose the medicines that form eutectic mix at their interaction:
A Chlorali hydras + Camphora
B Antipyrinum + Analginum
C Calcii chloridum + Natrii chloridum
D Ephedrini hydrochloridum + Glucosa
E Natrii hydrocarbonas + Hexamethylentetraminum
20. Pharmacy got the prescription for compounding mixtura. Choose the medicines that are incompartible:
A Papaverini hydrochloridum + Euphyllinum
B Novocainum + Dimedrolum
C Natrii bromidum + Natrii chloridum
D Codeini phosphas + Extractum herbae Thermopsidis
E Phenobarbitalum + Glucosa
NON-STERILE LIQUID MEDICINAL FORMS
1. What mass of Furacillini does pharmacist needs to weigh out for compounding of 500 ml of solution of Furacillini /1:5000/:
A *0,1 g
B 0,02 g
C 0,04 g
D 0,05 g
E 0,5 g.
2. What volume of standard (officinal) solution of Aluminii subacetatis does pharmacist need to measure for compounding of 100 ml 10% solution of Liquoris Burovi:
A *10 ml
B 25 ml
C 12,5 ml
D 30 ml
E 50 ml.
3. Pharmacist compounded 100 ml 20% solution of Formalin. Choose necessary volume of officinal solution of Formaldegidum:
A *20 ml
B 60 ml
C 10 ml
D 80 ml
E 40 ml.
4. What amount of Perhydrolum is necessary to be used for compounding of 100 ml of 3% solution of Hydrogenii peroxidum:
A *10,0 g
B 20,0 g
C 0,3 g
D 30,0 g
E 3,0 g
5. Solubility of High molecular medicines corresponds with their origin. Choose unlimitedly swelling medicinal matter:
A *Pepsin
B Starch
C Gelatin
D Pectin
E Methylcellulose.
6. Solution of limitedly swelling High molecular medicine was compounded in the pharmacy. What solution was labelled with the label “Heat up before use”:
A *Gelatin
B Tripsin
C Pepsin
D Methylcellulose
E Pancreatin
7. Pharmacist needs to compound oil emulsion with Menthol. Choose correct way of adding medicinal matter:
A *To solve in oil
B To disperse with adding of emulsion
C To solve in water intended for dilution of primary emulsion
D To solve in ready emulsion with heating up
E To add to ready primary emulsion.
8. It is necessary to compound emulsion for patient. Choose the oil that should be taken:
A *Peach oil
B Castor oil
C Vaseline oil
D Mint oil
E Tea tree oil
9. Pharmacist compounds heterogeneous medicinal form. Choose medicinal matter that should be added by the suspension type:
A *Phenylii salicylas
B Camfor
C Natrii coffein-benzoas
D Natrii bromidum
E Mentholum.
10. Decoction of Uvae ursi leaf is needed to be compounded. Choose correct proportion of medicinal plant material and extractant when there are no instructions in the prescription:
A *1:10
B 1:20
C 1:30
D 1:5
E 1:400.
11. Pharmacist compounded infusion of Thermopsis herb. When there are no instructions in the prescription it is compounded in proportion:
A *1:400
B 1:30
C 1:20
D 1:10
E 1:5.
12. What volume of water should be taken for compounding of 100ml of water extraction from Mint leaf (CWA = 2,4 ml/g)?
A *124 ml
B 110 ml
C 118 ml
D 121 ml
E 126 ml.
13. Pharmacist compounded water extraction by the method of cold infusion. Choose the plant matherial:
A *Radices Altheae.
B Cortex Frangulae
C Folia Menthae
D Folia Uvae ursi
E Herba Thermopsidis
14. Pharmacist compounded solution of Aethacridini lactas. Choose correct technology:
A *Dissolving in hot water
B Dissolving in freshly distilled water
C Dissolving in cold water
D Grinding in the mortar with water
E Dissolving in the solution of Kalii iodidi
15. Pharmacy reseived the prescription:
Rp.: Spiritus aethylici 20 ml
Resorcini 0,2
M.D.S. For skin rubbing
Choose correct technology:
A *Medicinal matter is weighed out in the vial for handling, then alcohol is measured.
B Alcohol is measured to the glass, then medicinal matter is weighed out.
C Alcohol is measured to the vial for handling, then Acidum bоricum is weighed out.
D Medicinal matter is weighed out to the glass then solvent is measured.
E Medicinal matter is grinded in the mortar, then solvent is added.
16. Pharmacist compounded solution by the prescription: Rp.: Sol. Formalini 30 %100 ml D.S. For shoes disinfection. Choose correct proportion of water and officinal (standard pharmacopoeia) solution:
A *70 ml and 30 ml
B 30 ml and 100 ml
C 20 ml and 80 ml
D 60 ml and 40 ml
E 67 ml and 33 ml
17. Pharmacist compounded suspension by the condensation method. Choose medicinal matters that form sediment:
A *Calcium chloride and Sodium hydrocarbonate
B Caffeine-sodium benzoate and Zinc oxide
C Sodium bromide and Camphor
D Potassium bromide and Sodium benzoate
E Magnesia sulfate and Potassium iodide
18. Pharmacist compounded oil emulsion with Zinci oxydum. Chhose correct way of adding of medicinal matter:
A *Adding by the type of suspension into ready-made emulsion
B Dissolution in oil
C Grinding with the water for diluting primary emulsion
D Dissolving in the water for compounding of primary emulsion
E Dissolving in the ready emulsion
19. Pharmacist compounded Oak bark (cortex Quercus) decoction. Choose the proportion of medicinal plant material and extractant:
A *1:10
B 1:400
C 1:30
D 1:20
E 1:5
20. . Pharmacist compounded infusion of Adonis herb. What is the feature of extraction technology?
A *Extraction is made in the neutral medium (neutral pH)
B Extraction is made in the weakly alkaline medium
C Extraction is made in the alkaline medium
D Extraction is made in the weakly acidic medium
E Extraction is made in the acidic medium
21. Pharmacy received the prescription for compounding of the infusion of Saponaria. What is the feature of saponines extraction?:
A * Extraction is made in the alkaline medium
B Extraction is made in the strongly acidic medium
C Extraction is made in the neutral medium
D Medium does not affect on extraction
E Extraction is made in the weakly acidic medium
22. Pharmacy received the prescription for compounding of the alcohol solution.
Rp.: Acidi salicylici 0,3
Spiritus aethylici 30 ml
Misce. Da. Signa. To wipe feet
What concentration of alcohol should be used?
A *70%
B 33%
C 95%
D 60%
E 80%
23. Pharmacist compounds 100 g of oil emulsion. What amounts of oil end emulsifier (gelatos) should be used?
A *10,0 and 5,0
B 10,0 and 15,0
C 7,5 and 10,0
D 10,0 and 7,5
E 1,5 and 0,75
24. Pharmacist compounded suspension with Bismuthi subnitras. What method did he use?:
A *Method of dispersing with stearing-up technique
B Method of physical condensation.
C Method of chemical condensation.
D Method of solvent change.
E Continental method.
25. Pharmacist compounds 100,0 of oil emulsion. What amount of oil is needed if there are no doctor’s instructions?
A *10,0.
B 20,0
C 30,0
D 15,0
E 50,0
26. Solution of Potassium permanganate is needed to be compounded for patient. What solvent should be used in this case?
A * Fresh distilled purified water
B Water for injections
C Alcohol
D Demineralized water
E Mint water
27. Pharmacist compounded mixture with 2.0 Sodium benzoate. What volume of 10% concentrated solution of Sodium benzoate did he use?
A * 20 ml.
B 2 ml.
C 8 ml.
D 10 ml.
E 12 ml.
28. For faster compounding of mixtures concentrated solutions are used. Calculate the volume of 5% Sodium hydrocarbonate solution needed for compounding of mixture with 2.0 g of medicinal matter.
A * 40 ml.
B 30 ml.
C 20 ml.
D 10 ml.
E 2, 5 ml.
29. Medicine is prescribed for patient by the prescription:
Rp.: Асіdi hydrochlorici 2%-100 ml
Da.Signa. 1 table spoon 3 times per day before meals.
What volume of Acidi hydrochlorici diluti (1:10) is necessary to measure for compounding of this medicine?
A *20 ml.
B 25 ml.
C 40 ml.
D 10 ml.
E 5 ml.
30. Medicine is prescribed for patient by the prescription:
Rp.: Sol. Асіdi borici spirituosae 3%-50 ml
Da.Signa. For gargling.
What concentration of alcohol should be used for this medicine compounding?
A * 70%
B 95 %
C 90 %
D 60 %
E 40 %
31. When suspension is compounded medicinal matter is grinded with small amount of liquid. Choose correct amount of liquid by the Deryagin’s rule for grinding 10 g of Zinci oxydum
A * 5 ml.
B 10 ml.
C 2 ml.
D 1 ml.
E 0,5 ml.
32. Stability of suspensions increases when substances that increase density of disperse environment are added. Choose the substance which has such properties.
A * Sugar syrup.
B Purified water.
C Alcohol.
D Dimethylsulfoxidum.
E Triaethanolminum.
33. Doctor prescribed 300 g of cod-liver oil emulsion. What amount of cod-liver oil does pharmacist need to weigh-out for compounding this emulsion?
A * 30,0 g.
B 60,0 g.
C 15,0 g.
D 3,0 g.
E 0,3 g
34. Pharmacist has compounded medicinal form by the prescription: Rp: Sol. Acidi acetici 3%-100ml D.S. For rubbing down. Choose correct amounts of officinal (standard pharmacopoeia) solution and water:
A *10 ml and 90 ml
B 3 ml and 100 ml
C 3 ml and 97 ml
D 15 ml and 85 ml
E 10 ml and 100 ml
35. Pharmacist has compounded infusion of Althea roots (Radices Altheae). What proportion of medicinal plant matherial and extractant has he used?
A *1:20
B 1:10
C 1:30
D 1:100
E 1:400
36. Water extractions of medical plant matherial (MPM) are compounded in the pharmacy. Choose the group of medicinal matters that are extracted in tightly closed infunder and collated after complete cooling?
A * essential oils
B alkaloids
C cardiac glycosides
D tannins
E saponins
37. Pharmacist compounded infusion of Valerian rhizomes with roots (Rhizoma cum radicibus Valerianae). Choose correct proportion of medicinal plant material and extractant for compounding:
A * 1:30
B 1:400
C 1:10
D 1:20
E 1:40
38. Pharmacist compounded suspension with 2 g of Streptocide. What amount of 5% solution of Methylcelulose is necessary to be used for suspension stabilisation?
A * 2,0
B 0,5
C 1,0
D 5,0
E 0,2
39. Pharmacist compounded 150.0 g of emulsion. What amount of oil did he tske if there are no instructions in the prescription?
A * 15,0
B 10,0
C 30,0
D 5,0
E 20,0
40. What amount of Aethacridini lactas should pharmacist weigh out for compounding of 200 ml of Aethacridini lactas solution (1:1000)?
A * 0,2
B 0,1
C 0,02
D 0,04
E 2,0
41. It is necessary to compound for patient suspension with 2.0 g of Menthol. What amount of 5% solution of Methylcellulose should be added for suspension stabilizing?
A * 4,0
B 0,5
C 1,0
D 0,4
E 2,0
42. Solution of Formalini 5%-100ml is prescribed. What amount of 37\% Formaldehidum should pharmacist use for compounding of solution.
A * 5 ml
B 12,5 ml
C 4,5 ml
D 10 ml
E 15 ml
43. In prescription mixture with 3.0 of Sodium benzoate is prescribed. Choose the correct amount of 10% solution-concentrate necessary for medicine compounding:
A * 30 ml
B 10 ml
C 20 ml
D 3 ml
E 5 ml
44. Pharmacist compounds suspension with 2.0 of Phenylii salysylas. Choose correct amount of 5% solution of Methylcellulose necessary for suspension stabilization:
A * 2,0
B 1,0
C 3,0
D 4,0
E 5,0
45. In prescription 100.0 of oil emulsion is prescribed. Choose amounts of oil, gelatos and purified water necessary for primary emulsion compounding according to Continental method:
A * 10,0; 5,0; 7,5 ml
B 20,0; 10,0; 30 ml
C 5,0; 10,0; 7,5 ml .
D 10,0; 5,0; 1,5 ml
E 5,0; 5,0; 5 ml .
46. Pharmacist compounded medicine according to prescription: Rp.: Sol. Protargoli 0,3% - 10 ml Glycerini 1,0 D.S. For irrigation. Choose correct technology:
A *Protargolum is grinded in the mortar with Glycerinum, then water is added.
B Glycerinum is dissolved in water and Protargolum is added.
C Protargolum is dissolved in the glass, then Glycerinum is added.
D Protargolum is weighed out in the vial, dissolved in water, then Glycerinum is added.
E Protargolum, water, Glycerinum are weighed out in the vial.
47. Pharmacist compounded suspension with hydrophobic substance. Choose the stabilizer of disperse system:
A *Twin-80
B Sodium chloride
C Solution of Hydrochloric acid
D Solution of Sodium hydroxide
E Esylonum
48. For dosing of small amounts of liquids pipette is used. Choose number of drops in 1 ml of purified water according to standard pipette:
A 20
B 50
C 30
D 40
E 10
49. Patient doses mixture by the table spoon. Choose its volume:
A *15 ml
B 25 ml
C 10 ml
D 20 ml
E 5 ml
50. Doctor prescribed 100 ml of infusion with 0.25 g of Thermopsis herb. What amount of dry extract-concentrate should pharmacist weigh out?
A * 0,25 g
B 0,5 g
C 0,3 g
D 0,2 g
E 0,1 g
51. Mint leaves (Folia Menthae) are handled for patient from pharmacy. What advices for compounding of infusion should pharmacist give to patient?
A * To compound the infusion in tightly closed pot
B To compound the infusion on opened fire.
C To compound the infusion at room temperature.
D To collate extraction immediately after preparing.
E After 15 minutes of extraction to cool the infusion.
52. Solution with Boric acid and Camfor should be compounded for patient. What solvent should doctor prescribe for physical incompatibility prevention?
A * Alcohol 70%.
B Purified water.
C Sunflower oil.
D Glycerin.
E Alcohol 40%.
53. Solution of Furacillini (1:5000) should be compounded in pharmacy. Choose the feature of dissolving of Furacillinum:
A * In boiling purified water with Sodium chloride
B In cold purified water.
C In minimal amount of alcohol.
D In purified water after grinding
E In pre-filtered purified water.
54. Mixture contains 3.0 of Sodium benzoate. What volume of 10% concentrated solution should be used?
A * 30 ml.
B 2 ml.
C 8 ml.
D 10 ml.
E 20 ml.
55. Solution of Hydrogen peroxide is handled from pharmacies in different concentrations. Solution of what concentration should be handled to patient if concentration is not denoted in the prescription?
A * 3%.
B 30 \%.
C 20 \%.
D 10 \%.
E 2 \%.
56. The medicine is prescribed for patient: Rp.: Sol. Liquoris Burovi 10\%-100 ml Da.Signa. Lotion. What volume of Liquoris Burovi should be measured for compounding this medicine?
A * 10 ml.
B 90 ml.
C 20 ml.
D 80 ml.
E 50 ml.
57. The mixture is prescribed for patient: Rp.: Sol. Асіdi hydrochlorici 2%-100 ml Da.Signa. 1 table spoon 3 t.p.d. before meals. What volume of Acidum hydrochloricum dilutum (1:10) should be measured for its compounding?
A * 20 ml.
B 25 ml.
C 15 ml.
D 10 ml.
E 5 ml.
58. 3% solution of Boric acid is prescribed for patient. What concentration of alcohol should be used for compounding of this solution?
A * 70%.
B 95 \%.
C 90 \%.
D 60 \%.
E 40 \%.
59. When suspension is compounded, medicinal matter is grinded with small amount of liquid. Choose correct volume of liquid according to Deryagin’s rule, that is necessary for grinding 20.0 g of Zinc oxide.
A * 10 ml.
B 5 ml.
C 2 ml.
D 1 ml.
E 0,5 ml.
60. Stability of suspensions increases when substances that increase density of disperse environment are added. Choose the substance which has such properties.
A * Glycerin.
B Purified water.
C Alcohol.
D Dimexidum
E Ether.
61. The method of suspension compounding depends on properties of its components. Choose hydrophobic substances:
A * Camphor, Menthol.
B Sodium hydrocarbonate, Sodium sulfate.
C Boric acid, Calcium carbonate.
D Zink oxide, Talcum.
E Bolus alba, Bentonite.
62. The doctor prescribed emulsion of Olive oil (Oleum olivarum) with Anaesthesinum. Choose the feature of adding Anaesthesinum:
A * To solve Anaesthesinum in oil before emulsion compounding
B To solve Anaesthesinum in ready-made emulsion
C To solve Anaesthesinum in purified waterу
D To solve Anaesthesinum in primary emulsion.
E To solve Anaesthesinum in alcohol, then add to primary emulsion
63. Althea roots infusion is compounded for patient. What regime of infusion should pharmacist use for this mixture compounding?
A * 30 minutes at room temrepature.
B 60 minutes at room temrepature.
C 15 minutes infusion in a water bath and 45 minutes cooling at room temrepature.
D 30 minutes infusion in a water bath and 10 minutes cooling at room temrepature.
E 30 minutes infusion in a water bath and immediate collating without cooling.
64. The doctor prescribed mixture with several types of medicinal plant material. Choose medicinal plant material that can be extracted in one infunder.
A * Mint leaves (Folia Menthae), Chamomile flowers (Flores Chamomillae).
B Mint leaves (Folia Menthae), Folia Uvae ursi.
C Mint leaves (Folia Menthae), Althea roots (Radices Altheae).
D Mint leaves (Folia Menthae), Cortex Frangulae.
E Mint leaves (Folia Menthae), Flax seeds (Semina Lini).
65. Pharmacy received the prescription for compounding of infusion. What medicinal plant material can be used for compounding of this medicinal form?
A * Rhizomes with roots of Valerian (Rhizomata cum radices Valerianae)
B Roots of Rheum (Radices Rhei)
C Oak bark (Cortex Quercus)
D Viburnum bark (Cortex Viburni)
E Frangula bark (Cortex Frangulae)
66. According to doctor’s prescription in the pharmacy should be compounded emulsion with Phenylii salysilas in its composition. What is the correct way of adding of medicinal matter to the emulsion?
A * to grind according to the Deryagin’s rule with the ready-made emulsion
B to grind with the emulsifier and oil
C to dissolve in the ready-made emulsion
D to dissolve in the water for diluting of primary emulsion
E to dissolve in oil
67. Pharmacist compounded solution of Ichthyolum. Choose the feature of dissolving of Ichthyolum
A To weigh out Ichthyolum in the porcelain cup, then add water with mixing, to collate to the vial
B To weigh out Ichthyolum in tared vial, to add water, to filtrate
C To weigh out Ichthyolum in tared mortar and to grind with water
D To put water into the vial, to add Ichthyolum, to filtrate
E To weigh out Ichthyolum in the glass, to add water, to dissolve and to collate to the vial
68. Emulsions as heterogeneous systems can flake under the influens of different factors. What factor causes flaking of emulsions faster then others?
A *Adding of strong electrolytes
B Diluting with water
C Diluting with oil
D Adding of an excess of emulsifier
E Adding of syrups
69. Pharmacist compounded medicine by the prescription:
Rp.: Acidi borici 0,1
Glycerini 10,0
M.D.S. Ear drops.
What technology should he choose?
A * To put to the vial for handling Boric acid, then Glycerin and to heat up
B To grind Boric acid with Glycerin in the mortar.
C To put to the vial for handling Glycerin, to add Boric acid, to heat up
D To put to the glass Glycerin, to dissolve Boric acid in it
E To put to the porcelain cup Glycerin, to dissolve Boric acid in it.
70. What technology should pharmacist use for compounding of Starch solution?
A * To mix with cold water, to pour to the boiling water and to boil during 1-2 minutes.
B To mix with hot water, then pour to cold water.
C To dissolve in cold water, then to heat up.
D To dissolve in the vial for handling in fresh-distilled and filtered purified water
E To dissolve in boiling water.
71. Pharmacist compounded water solution of Protargolum. What technology did he use?
A * He sprinkled Protargolum on the surface of the water and left for complete dissolution.
B He dissolved Protargolum in the vial for handling in purified water.
C He dissolved it with grinding.
D He dissolved it in warm water.
E He dissolved it in cold water.
72. Pharmacist compounded decoction of Senna leaves (Folium Sennae). Choose the correct time of its cooling:
A * 3 hours.
B 45 minutes.
C 10 minutes.
D Do not cool.
E 15 minutes.
73. Pharmacist compounded infusion of Leonurus herb (Herba Leonuri) with Sodium bromide. What way of adding Sodium bromide did he choose?
A * He dissolved it in collated extraction in the glass.
B He added concentrated solution to the ready-made extraction
C He dissolved it in the infunder.
D He dissolved it in the infusion in the vial for handling.
E He mixed it in a separate bowl with the part of extraction, then added it to the ready-made extraction.
74. Pharmacist compounded medicine by the prescription:
Rp.: Spiritus aethylici 70% 30 ml Acidi salicylici 0,3 M.D.S. For skin rubbing. What technology did he use?
A He put medicinal matter into the vial for handling, then measured alcohol.
B He measured solvent to the glass, weighed out medicinal matter, filtered to the vial
C He measured alcohol to the vial for handling and weighed out Salicylic acid.
D He weighed out medicinal matter to the glass and measured the solvent, then collated solution to the vial for handling.
E He grinded medicinal matter in the mortar, added the solvent, moved solution to the vial for handling.
75. Pharmacist compounded emulsion. How did he add Phenylii salycilas to the medicinal form?
A He added it by the type of suspension to the ready-made emulsion
B He grinded it with water for dilution of primary emulsion
C He dissolved it in oil
D He dissolved it in water for compounding primary emulsion.
E He dissolved it in the ready-made emulsion.
76. Pharmacist made a mistake in water temperature compounding the infusion of Althea roots (Radices Altheae), so the ready-made product was cloudy. What water temperature should be used for extraction of this plant matherial?
A *Room temperature
B 400С
C 1000С
D 600С
E 800С
77. For removing of edema hypertonic solutions are used in medical practice. Choose the name of process, that occurs in blood when such solution is injected:
A * Plasmolysis
B Hydrolysis
C Hemolysis
D Lypolysis
E Electrolysis
78. Pharmacist compounded 100.0g of oil emulsion using as emulsifier 5% solution of Methylcellulose. Choose correct amounts of oil and emulsifier, that should be used for medicine compounding:
A *10,0 g, 20,0 g
B 20,0 g, 30,0 g
C 10,0 g, 10,0 g
D 10,0 g, 30,0 g
E 20,0 g, 10,0 g
79. Pharmacist compounded 2 % water solution, dissolving medicinal matter in mortar with grinding. Choose medicinal matter which needs this technology:
A * Potassium permanganate
B Calcium gluconate
C Osarsolum
D Boric acid
E Potassium bromide
80. Pharmacist compounds oil emulsion. Choose correct way of adding Camphor to the medicinal matter:
A * To dissolve in oil
B To dissolve in alcohol
C To dissolve in water
D To dissolve in ether
E To dissolve in Glycerin
81. Pharmacist compounds oil emulsion. Choose the name of medicinal matter that is added to emulsion by the way of suspension:
A * Phenylii salycilas
B Camphor
C Caffeini-natrii bensoas
D Chloralum hydrate
E Potassium bromide
82. Pharmacist compounded 200 ml of 2% solution of Sodium hydrocarbonate. What amounts of Sodium hydrocarbonate and water did he use?
A * 4.0 and 200 ml
B 2.0 and 200 ml
C 4.0 and 196 ml
D 2.0 and 199 ml
E 4.0 and 199 ml
83. Pharmacist compounded medicine by dissolving medicinal matter in water with adding of Acidum hydrochloridum dilutum (1:10). What substance needs such technology?
A * Pepsin
B Tannin
C Osarsolum
D Cpllargolum
E Cuprum sulfas
84. Pharmacist compounded glycerine solution of Boric acid. Choose correct way of adding of Boric acid:
A *To dissolve in the vial when heating
B To dissolve in the mortar when grinding
C To dissolve in the glass at room temperature
D To grind with alcohol in the mortar and to mix with Glycerin
E To dissolve in the measuring flask
85. Pharmacist compounded 180 ml of infusion of Herba Convallaria. Choose correct amount of medicinal plant material that should be used for compounding of this medicine:
A *6.0
B 10.0
C 18.0
D 0.5
E 9.0
86. Pharmacy received the prescription which contains High-molecular medicine. Choose the name of limitedly swelling medicine:
A * Gelatin
B Ichthiolum
C Tannin
D Pepsin
E Extract Glycyrrhizae
87. Pharmacist compounded 100 ml of 1% Ammonia solution. What amounts of 10 % раствора Ammonia solution and water did he use?
A * 10 ml and 90 ml
B 5 ml and 95 ml
C 15 ml and ml
D 20 ml and 80 ml
E 5 ml and 100 ml
88. Pharmacist used for suspension stabilizing Potassium soap (Green soap). What medicinal matter is the part of this suspension?
A * Sulfur
B Phenylii salicylas
C Menthol
D Bismuth subnitras
E Camphor
89. Pharmacist compounded emulsion for internal use with Phenylii salicylas. Choose correct way of substance adding:
A *To add by the suspension type to the ready-made emulsion.
B To dissolve in oil.
C To dissolve in water for diluting of primary emulsion.
D To dissolve in water for compounding of primary emulsion.
E To dissolve in Glycerin.
90. Pharmacy received the prescription for compounding of 3% alcohol solution of Boric acid. What concentration of alcohol should pharmacist use for medicines compounding?
A * 70\%;
B 60\%;
C 40\%;
D 90\%;
E 96\%.
91. Althea roots infusion is compounded in pharmacy using the method of cold extraction. Choose correct time of infusion:
A * 30 minutes;
B 20 minutes;
C 40 minutes;
D 50 minutes;
E 60 minutes.
92. Pharmacist compounds suspension with 2.0 g of Camphor. Choose the amount of Gelatos for suspension stabilizing:
A * 2.0;
B 1.0;
C 3.0;
D 4.0;
E 6.0.
93. Pharmacy received the prescription for mixture compounding: Rp.: Analgini 2,0 Natrii bromidi 3,0 Aquae Menthae 200 ml Tinct. Convallariae Tinct. Valerianae ana 5,0 M.D.S. 1 table spoon 3 t.p.d. Choose amount of aromatic water for drug compounding:
A * 200 ml;
B 190 ml;
C 185 ml;
D 180 ml;
E 184 ml.
94. Doctor prescribed: Iodum 0.5 g, Purified water 10 ml. What auxiliary component should be used for compounding of this medicine?
A * Potassium iodide
B Potassium bromide
C Sodium hydrocarbonate
D Sodium chloride
E Sodium bromide
95. Pharmacy received the prescription for compounding of the solution of Hydrogen peroxide without instructions about its concentration. Solution of Hydrogen peroxide of what concentration should be handled?
A *3%;
B 6\%;
C 5\%;
D 1,5\%;
E 30\%.
96. Pharmacist has compounded solution according to the prescription: Rp.: Acidi salicylici 0,3; Spiritus aethylici 30 ml; Misce. Da. Signa. Choose alcohol concentration:
A 70%
B 60\%
C 40\%
D 90\%
E 95\%
97. For compounding of Collargolum solution pharmacist filtered water to the vial for handling, put there Collargolum and shake up. For what concentrations of Collargolum should be used this technology?
A *less then 1%
B less then 2\%
C less then 5\%
D less then 10\%
E less then 20\%
98. For compounding suspension of what medicinal matter should be added 5% solution of Methylcellulose as a stabilizer?
A *Terpinhydrate
B Magnesium oxide
C Starch
D Bismuth subnitras
E Zinc oxide
99. Фармацевт приготував суспензію методом диспергування (скаламучуванням). З якою з перерахованих речовин він приготував препарат?
A * Bismuth subnitras
B Camphor
C Streptocide
D Terpinhydrate
E Menthol
100. Pharmacist compounds nonaqueous solution according to the prescription:
Rp: Natrii tetraboratis 5,0 Glycerini ad 20,0 M.D.S. For rubbing.
What technology should he use?
A * To Put Sodium tetraborate into dry vial for handling, to weigh out Glycerine, to heat up.
B To grind Sodium tetraborate in the mortar with Glycerin.
C To weigh out Glycerine into the vial for handling, to put Sodium tetraborate, to heat up.
D To measure Glycerine into the glass, to dissolve Sodium tetraborate.
E To weigh out Glycerine into the glass, to add Sodium tetraborate, to heat up, to filter to the vial for handling.
101. Solutions of protected colloids are used in medical practice. What substance is protected colloid?
A * Prothargolum
B Bismuth subnitras
C Potassium iodide
D Camphor
E Sodium chloride
102. Suspensions as heterogeneous systems are kinetically and sedimentationally not stable. Choose medicinal matter which is used for increasing of stability of suspensions with hydrophobic substances:
A * Gelatos
B Sodium chloride
C Boric acid
D Sodium sulfate
E Glucose
103. Suspensions are compounded in pharmacy. What medicinal matter does not need adding of stabilizer for compounding of suspension?.
A * Magnesium oxide
B Camphor
C Sulfur
D Menthol
E Phenilii salycilas
104. Pharmacist compounds medicine according to the prescription:
Rp: Solutionis Natrii hydrocarbonatis 2% - 30 ml // Solutionis Calcii chloridi 20% - 60 ml // Liquoris Ammonii-anisati 2,5 ml // Misce. Da. Signa. 1 table spoon 4 times per day. What type of disperse system forms in this case?
A * suspension
B emulsion
C colloid solution
D true solution
E solution of high-molecular medicine
105. Gelatos is added to emulsion system. What role does Gelatosa perfoms in emulsions?
A * emulsifier
B preservative
C solvent
D taste coregent
E antioxidant
106. Pharmacist needs to compound water extraction of medicinal plant material. What can replace plant material when medicine is compounded?
A * Standard extract-concentrate
B Tincture
C Liquid extract
D Dense extract
E Aromatic water
107. Water extraction of Thermopsis herb (Herba Thermopsidis) is compounded in the pharmacy. What components should be used for preparing this water extraction?.
A * Herba Thermopsidis, solution of Hydrochloric acid 1:10, purified water
B Herba Thermopsidis, Sodium hydrocarbonate, purified water
C Herba Thermopsidis, Sodium chloride, purified water
D Herba Thermopsidis, purified water
E Tinctura Thermopsidis, purified water
108. Liquid medicinal forms are compounded using concentrated solutions or CVI (coefficient of volume increasing) when medicinal matters are dissolved if as a solvent is used:
A *Purified water
B Aromatic waters
C Glycerin
D Alcohol
E Polyethylenglycole-400
109. Choose liquid ingredient which is dosed by the volume when liquid medicinal forms are compounded:
A *Elixirum pectoralis
B Dimexidum
C Methylii salicylas
D Polyethylenglycole-400
E Perhydrole
110. Pharmacist compounded 150 ml of infusion of Adonis vernalis using dry concentrated extract [1:1]. What amount of this extract should he weigh out?
A 5,0
B 7,5
C 10,0
D 15,0
E 22,5
111. What is the time of infusion on a boiling water bath when decoctions with volume 1000-3000 ml are compounded
A 40 minutes
B 25 minutes
C 30 minutes
D 45 minutes
E 15 minutes
112. Infusions of the plant materials which are rich in water soluble substances are called:
A Mucuses
B Decoctions
C Infusions
D Extraction
E Tinctures
113. Transference of substance as a result of liquids movement when it is shacked, mixed or temperature is changing is called:
A Convection diffusion
B Molecular diffusion
C Osmosis
D Dialysis
E Emulgation
114. What volume of water should be taken for compounding 200 ml of water extraction of Herba Leonuri [CWA (coeficient of water absorbtion) =2 ml /g]?
A 240 ml
B 220 ml
C 200 ml
D 160 ml
E 210 ml
115. Pharmacist compounded medicine according to the prescription:
Rp.: Acidi hydrochlorici 4 ml
Aquae purificatae 200 ml
M.D.S.
What volumes of 10% solution of Hydrochloric acid and of water should be taken?
A *40 ml and 164 ml
B 40 ml and 160 ml
C 4 ml and 200 ml
D 4 ml and 196 ml
E 40 ml and 200 ml
116. Pharmacist has compounded solution according to the prescription:
Rp.: Sol. Liquoris Kalii acetates 10% 200ml D.S.
What volumes of solution of Potassium acetate [34% officinal solution] and of water should be taken?
A 20 ml and 180 ml
B 10 ml and 190 ml
C 59 ml and 141 ml
D 20 ml and 200 ml
E 59 ml and 180 ml
117. What medicinal matter in drugs compounding is dosed by mass?
A Perhydrolum
B Liquor Ammonii anisatum
C 1\% alcohol solution of Citralum
D Tinctura Belladonnae
E Elixirum Pectorale
118. For compounding of 2% alcohol solution of Boric acid pharmacist weighed out to the vial for handling Boric acid and weighed out alcohol. Was this technology correct, or not?
A * Technology was incorrect because alcohol should be dosed by volume
B Technology was incorrect, because alcohol solution should be compounded with heating up
C Technology was incorrect, because alcohol should be measured to the vial first
D Technology was incorrect, because compounded solution should be filtered
E Technology was correct and corresponds with rules of compounding of alcohol solutions.
119. Pharmacist compounds 200 ml mixture with 4.0g of Sodium bromide. What volumes of purified water and 20% solution of Sodium sulfate should he use?
A 180 ml and 20 ml
B 160 ml and 40 ml
C 192 ml and 8 ml
D 184 ml and 16 ml
E 190 ml and 10 ml
120. Pharmacist compounded medicine by dissolving medicinal matter in hot water. Choose substance that needs such technology:
A *Boric acid
B Sodium hydrocarbonate
C Sodium chloride
D Sodium bromide
E Ascorbic acid
121. Pharmacist compounds infusion of Herba Convallaria. In what proportion should he compound this extraction according to the State Pharmacopoeia?
A 1:30
B 1:20
C 1:10
D 1:400
E 1:5
122. Pharmacist compounds 3000 ml of infusion of Valerian root for the department of hospital. Choose the correct time of infusion for this amount of extraction on the water bath:
A 25 minutes.
B 45 minutes.
C 15 minutes.
D 10 minutes.
E 30 minutes.
123. Pharmacist compounded 100 ml 3% solution of Hydrogen peroxide. What amounts of 30 % solution of Hydrogen peroxide and of water did he use?
A 10 ml and 90 ml
B 1 ml and 99 ml
C 3 ml and 97 ml
D 30 ml and 70 ml
E 20 ml and 80 ml
124. Pharmacist compounded oil solution of Menthol. Choose correct temperature of dissolving of medicinal matter:
A 50-60 °С
B 60-70 ° С
C 30-40 °С
D 70-80 ° С
E 20-30 ° С
125. Pharmacist compounded suspension with hydrophobic medicinal matter. Choose stabilizer for its compounding:
A *Solution of Methylcellulose 5 %
B Sodium thiosulfate
C Glucose
D Sodium chloride
E Polyethylenooxide
126. Pharmacist compounded suspension. Choose amount of liquid for execution of Deryagin’s rule:
A 0.4-0.6 ml for 1.0 of substance
B 1-0.8 ml for 1.0 of substance
C 1.5-0.7 ml for 1.0 of substance
D 0.9-2 ml for 1.0 of substance
E 0.1-1.0 ml for 1.0 of substance
127. Pharmacist compounded emulsion. Choose correct way of adding of oil-soluble medicinal matter:
A To dissolve in oil
B To dissolve in purified water
C To add in a dry form
D To add to the ready-made emulsion
E To add to the emulsifier.
128. Pharmacist compounded 100,0g of oil emulsion. Choose necessary amount of Twin-80:
A 2.0
B 4.0
C 6.0
D 10.0
E 1.0
129. What technological method should be used when solutions of Cuprum sulfate are compounded?
A *Grinding with water in the mortar
B Heating up
C Previously dissolving in Glycerin
D Previously dissolving in 95\% alcohol
E Adding of Carbo activatus
130. Pharmacy received the prescription:
Rp.: Extracti Belladonnae 0.2
Analgini 1.0
Solutionis Calcii chloridi 2% 200 ml
Misce. Da. Signa. 1 table spoon 3 t.p.d.
What volume of concentrated solution of Calcium chloride should be used?
A *20 ml
B 4 ml
C 5 ml
D 10 ml
E 40 ml
POWDERS
1. Choose the packing material for handling powders with Camphora:
A *Parchment capsules
B Cellophane capsules
C Paraffin capsules
D Wax capsules
E Paper capsules
2. Pharmacist compounded 10 powders with Atropini sulfas 0,00005 per dose. What trituration did he use?
A *1:100
B 1:10
C 1:1000
D 1:50
E 1:20
3. Trituration of Atropini sulfas is compounded in pharmacy. What auxiliary matter shoud be used?
A * Lactic sugar
B Saccharosa
C Lactosa
D Starch
E Talcum
4. Pharmacist-technologist needs to compound 5,0 gr of trituration Atropini sulfas (1:100). Choose the amounts of poisonous matter and lactic sugar:
A *0,05:4,95
B 1,0:4,0
C 0,1:4,9
D 0,5:4,5
E 0,01:4,99
5. Pharmacist needs to compound powders by the prescription: Rp: Camphorae 0,1 Glucosi 0,25 M.f.pulv. D.t.d.N 10 S. 1 powder 3 t.p.d. Choose the correct technology:
A * to grind Glucosa first, take it off to the capsule, to grind Camphora with alcohol, to mix
B to weigh out Camphora to the mortar, to add Glucosa, to mix
C to grind Glucosa first, take it off to the capsule, to grind Camphora, to mix
D to put Camphora between the layers of Glucosa, to mix
E to grind Glucosa with alcohol, to add Camphora, to mix
6. Pharmacist needs to compound powders with Camphora. What capsules should he use for packing?
A * Parchment
B Paper
C Wax
D Paraffin
E Cellophane
7. Pharmacist-technologist compounded 10,0 gr of trituration of Aethylmorphini hydrochloridum (1:100). What amount of poisonous matter and excipient did he take?
A *0,1 Aethylmorphini hydrochloridum and 9,90 of sugar
B 0,01 Aethylmorphini hydrochloridum and 9,99 of sugar
C 0,1 Aethylmorphini hydrochloridum and 10,0 of sugar
D 0,05 Aethylmorphini hydrochloridum and 9,95 of sugar
E 1,0 Aethylmorphini hydrochloridum and 9,0 of sugar
8. Pharmacist needs to weigh out the medicinal matter of common table - Glucosa. What minimal amount of Glucosa can he weigh out on HS-1?
A * 0,02
B 0,01
C 0,03
D 0,04
E 0,05
9. 0,0001 of Atropinum sulfas is prescribed. Choose the amount of trituration (1:100), needed for compounding 10 powders:
A * 0,10
B 0,20
C 0,50
D 0,01
E 0,02
10. Pharmacist needs to compound trituration of Platyphyllini hydrotartras (1:10). Choose the excipient for trituration compounding:
A * Lactic sugar
B Refined sugar
C Corn starch
D Rise starch
E Mannitum
11. Pharmacist compounded the medicinal form: Rp.: Magnesii oxydi Natrii hydrocarbonatis ana 0,2 M. f. pulv. D. t. d. №12. S. 1 powder 3 t.p.d. Choose the correct technology:
A To grind Natrii hydrocarbonatis, to add Magnesii oxydum, to mix
B To grind Magnesii oxydum, to add Natrii hydrocarbonatis, to mix
C To grind Natrii hydrocarbonatis with alcohol, to add Magnesii oxydum, to mix
D To grind a part of Magnesii oxydum, to add Natrii hydrocarbonatis, to add the remained amount of Magnesii oxydum, to mix
E To grind Magnesii oxydum with alcohol, to add Natrii hydrocarbonatis, to mix
12. Pharmacist compounds powders with Platyphyllini hydrotartras. Choose the minimal amount of poisonous matter, that can be weighed out on HS-1:
A 0,05
B 0,02
C 0,03
D 0,1
E 0,15
13. Pharmacist compounded 20,0 of trituration of Atropini sulfatis (1:100). What amounts of poisonous matter and excipient did he use?
A 0,20 and 19,8
B 0,02 and 19,98
C 0,1 and 19,0
D 2,0 and 18,0
E 0,20 and 20,0
14. Pharmacist compounded medicinal form by the prescription. : Rp.: Papaverini hydrochloridi 0,01 Sachari 0,25 M.f. pulv. D.t.d. №10 S. 1 powder 3 t.p.d. Calculate mass of one powder
A 0,26
B 0,23
C 0,22
D 0,28
E 0,25
15. Powders with 0.02 of Belladonna Extract for one powder should be compounded in pharmacy. What amount of dry extract of Belladonna (1:2) did pharmacist weigh out for 10 powders compounding?
A * 0,4 g.
B 0,6 g.
C 0,5 g.
D 0,8 g.
E 0,2 g.
16. Powders with Menthol should be made for patient. Choose correct technology of grinding Menthol:
A * To grind with alcohol or ether.
B To grind with chloroform or glycerin.
C To grind with purified water.
D To grind with other components of prescription.
E To grind with sugar.
17. Trituration of Scorolamini hydrobromidi is compounded in pharmacy. What component should be used for compounding except of poisonous matter?
A * Lactis sugar.
B Saccharose.
C Glucose.
D Starch.
E Talcum.
18. Triturations of poisonous and strong effective medicinal matters are made in pharmacies. In what proportions can they be compounded?
A * 1: 10 and 1:100.
B Only 1:10.
C 1:1000.
D 1: 500.
E Only 1:100.
19. Pharmacist compounds powders with Riboflavinum. How should Riboflavinum be mixed with powder?
A * To use “the method of three layers”.
B To use sifted Riboflavinum.
C To use the principle of mixing “from less to highest”.
D To use the principle of mixing “from highest to less”.
E To add Riboflafinum over the prepared mixture of powders.
20. Pharmacist compounds powders with Papaverini hydrochloridi. Choose hand scales for weighing out 0,05 g of substance:
A * HS 1,0
B HS 5,0
C HS 20,0
D HS 10,0
E HS 2,0
21. Pharmacist compounded powders with Streptocidum. Choose correct way of adding of Streptocidum:
A * To grind with alcohol
B To add as a trituration
C To use “the method of three layers”
D To add at the end of compounding and mix for homogeneity
E To add first grinding with Glycerin
22. Scopolamini hydrobromidum is prescribed by 0,0002 for one powder in prescription. What amount of trituration 1:100 should be taken for preparing 10 powders?
A * 0,2;
B 0,04;
C 4,0;
D 0,4;
E 2,0.
23. Pharmacy received the prescription with the doctor’s instruction about handling powders in gelatinous capsules. What medicinal matter is included into composition of this powders:
A * Aethacridini lactas.
B Magnesii oxydum.
C Streptocidum
D Dimedrolum.
E Glucose.
24. During the compounding of powders in pharmacy physical and chemical properties of ingredients are taken into account. What medicinal matter is added to powders without grinding?
A * Starch.
B Camphor.
C Menthol
D Salicylic acid
E Streptocide.
25. Pharmacy received the prescription: Rp.: Dibazoli 0.05 Papaverini hydrochloridi 0.15 Sacchari 2.5 M. fiat pulv. Divide in partes aequales № 10. Choose the weight of the one powder:
A 0,27
B 2,7
C 0,25
D 0,26
E 0,30
26. Powders are taking important place among extemporal medicinal forms. What component is added to powders without grinding?:
A * Bismuthi subnitras
B Ascorbic acid
C Camphor
D Xeroformium
E Calcium gluconate
27. Pharmacist compounds powders by prescription: Rp: Proserini 0,002 Sacchari 0,25 Misce ut fiat pulver. Da tales doses N 10. Signa. 1 powder 2 times per day after meals. Choose amounts of ingredients for compounding this powders.
A *Trituration of Proserine (1:10) 0,2 g; Sugar 2,3 g
B Trituration of Proserine (1:10) 0,2 g; Sugar 2,5 g
C Proserine 0,02 g; Sugar 2,5 g
D Trituration of Proserine (1:100) 2,0 g; Sugar 2,5 g
E Trituration of Proserine (1:100) 0,2 g; Sugar 2,3 g
28. Pharmacist compounds powders with Athropini sulfas in amount 0,0003 г for 1 dose. Calculate the amount of trituration of Athropini sulfatis (1: 100) for compounding 10 powders:
A 0,3
B 0,03
C 3,0
D 0,27
E 2,7
29. Pharmacist compounds powders by prescription: Rp.: Scopolamini hydrobromidi 0,0003 Ephedrini hydrochlorodi 0,05 Sachari 0,15 M.f. pulvis D.t.d. № 10 S. 1 powder 3 times per day. Calculate the mass of one powder if trituration (1:100) is used:
A 0,20
B 0,15
C 0,23
D 0,17
E 0,203
30. Pharmacist compounds powders by “the method of three layers”. Choose medicinal matter that needs this technology:
A *Riboflavine
B Glucose
C Analgine
D Ascorbic acid
E Sodium hydrocarbonate
31. Pharmacist compounds powders grinding one of the components of the prescription with alcohol. Choose medicinal matter that needs this technology:
A * Streptocide
B Starch
C Talcum
D Zinc oxide
E Bolus alba
32. What medicinal mattes should be grinded with auxiliary liquids for compounding powders?
A *Acidum Salicylicum, Natrii tetraborate, Streptocide
B Glucose, Natrii hydrocarbonate , Dybasolum
C Mentholum, Camphora, Dermatolum
D Iodum, Magnesii oxidum, Acidum Salicylicum,
E Natrii tetraborate, Thymolum, Zinci oxydum.
33. Effervescent powders are made in the pharmacy. What medicinal matter, except of Citric Acid, is included to the powders composition?
A * Natrii hydrocarbonate
B Magnesii oxydum
C Natrii chloridum
D Natrii sulfas
E Sugar
34. Simple dosed powders are compounded in pharmacy. What technologic operation is not necessary for compounding of these powders?
A * Mixing
B Grinding
C Dosing
D Packaging
E Labeling
35. Pharmacy received prescription for compounding of powder for external use that includes hard-grinded medicinal matter. What auxiliary liquid can pharmacist use for grinding of this medicinal matter?
A * Medicinal Ether;
B Purified water;
C Water for injections;
D Dimexidum;
E Isopropyl alcohol;
36. Choose the type of powders which quickly react with water with evolution of carbon dioxide:
A * Effervescent powders;
B Soluble powders;
C Powders for oral use;
D Nasal powders;
E Powders for external use.
37. Pharmacy received prescription for compounding of complex powder that includes dyeing medicinal matter. What medicinal matter is dyeing?:
A * Aethacridini lactas (rivanolum);
B Camphor;
C Sthreptocidum;
D Bismuthi subnitras;
E Prothargolum.
38. Calculate the amount of dry Belladonna extract (1:2) for compounding of medicinal form: Extraсti Belladоnnae 0,015 Magnesii oxydi 0,5 Natrii hydrocarbonatis 0,2 Misce ut fiat pulvis Da tales doses №10 Signa. 1 powder 3 times per day.
A * 0,3
B 0,15
C 0,4
D 0,6
E 0,015
39. This medicinal matter has blue color, but does not leave colored mark on surfaces; powders with this medicinal matter are compounded using common rules of compounding. Choose this medicinal matter:
A * Cupri sulfas
B Aethacridini lactas
C Riboflavinum
D Acrichinum
E Furacillinum
SOFT MEDICINAL FORMS
1. Pharmacist needs to compound suppositories on hydrophobic base with Protargolum. Choose the method of adding Protargolum :
A * To disperse with Glycerinum, to add water and to emulsify
B To dissolve in a part of molten base
C To dissolve in all molten base
D To add as very fine powder
E To grind with some drops of fat oil
2. A pharmacist compounded eye ointment with Norsulfazolum. Specify the type of disperce system that is formed by Norsulfazolum with the basis:
A *Ointment-suspension
B Ointment- emulsion
C Ointment-solution
D Ointment-alloy
E Combined ointment
3. Pharmacist compounded suppositories with Novocaine in amount less then 5 % by the method of rolling out. Specify the method of adding Novocaine to the basis:
A *To dissolve in minimal amount of water
B To dissolve in minimal amount of castor oil
C To dissolve in minimal amount of alcohol-water-glycerin mix
D To dissolve in molten base
E To dissolve in alcohol
4. Pharmacist compounded liniment-suspension. Specify the method of adding dry matters:
A *To disperce in the mortar by Deryagin rule with liquid components
B To weigh out to the vial and to add liquid components
C To measure liquid components to the mortar and to add dry matters
D To mix in the glass with liquid components
E To grind gry matters in evaporating cup and to mix with liquid components
5. A pharmacist compounded ointment-suspension on lipophilic basis. Specify the matter that forms such type of ointment:
A *Xeroformium
B Protargolum
C Mentholum
D Tanninum
E Plant extracts
6. Pharmacist compounded ointment-solution on lipophilic basis. Specify the matter that forms such type of ointment:
A *Mentholum
B Novocainum
C Dermatolum
D Starch
E Sulfur
7. Pharmacist compounded suppositories with streptocide on polyaethylenoxide basis. Specify the method of adding medicinal matter to the basis:
A *Dissolution in molten basis
B Emulsifying and mixing with basis
C Grinding with water
D Adding by the type of suspension
E Mixing with vaseline oil
8. A pharmacist compounded suspensive ointment. Specify the medicinal matter that forms such type of ointment:
A *Zinc oxide
B Protargolum
C Mentholum
D Ichthyolum
E Potassium iodide
9. A pharmacist compounded ointment on vaseline. Specify the matter that should be added to warm basis at 400С:
A *Camphor
B Anaesthesinum
C Benzoic acid
D Streptocide
E Vinilinum
10. A pharmacist compounded ointment on hydrophilic basis. Specify the basis that has osmotic action:
A *Polyaethylanoxide
B Gelatin-glycerin
C Vaseline
D Spermaceti
E Hydrogenated fats
11. A pharmacist compounded marbles on gelatin-glycerine basis. Specify the corellation of gelatin, glycerina and water:
A *1:5:2
B 3:3:3
C 1:6:3
D 4:1:4
E 1:1:8
12. Pharmacist prepared suppositories on fatty basis by the method of outpouring. Specify the basis that should be taken:
A *Butyrolum
B Vaselinum
C Cacao butter
D Wax
E Spermaceti
13. A pharmacist prepared suppositories by the method of outpouring. What coefficient did he use for the calculations of gelatin-glycerin basis?
A *Coefficient of count
B Coefficient of volume increase
C Coefficient of water absorbtion
D Isotonic coefficient
E Coefficient of general losses
14. A pharmacist prepared paste by prescription .
Rp.: Zinci of oxydi
Amyli ana 10,0
Vaselini 20,0
Misce ut fiat pasta
Da. Signa. To inflict on the staggered areas of skin
Specify the feature of it’s technology.
A *To melt prescribed amount of vaseline for dispergating of medicinal matters.
B To grind Zinc oxide and starch with alcohol.
C To grind Zinc oxide and starch with vaseline oil.
D To mix medicinal matters with unmolten basis.
E To grind medicinal matters with glycerin.
15. A Pharmacist-technologist accepted prescription on ointment.
Rp.: Unguenti Resorcini 1,5 % - 10,0
Da. Signa. To inflict on the staggered areas of skin.
How did pharmacist add dry matter to a medical form?
A *grinded with a few drops of vaseline oil
B grinded with a few drops of alcohol
C grinded with a few drops of water
D added to molten vaseline
E grinded with part of vaseline
16. A doctor prescribed pessaries and did not specify their mass. What mass must pessaries be prepared in a pharmacy ?
A *4,0
B 3,0
C 1,5
D 0,5
E 6,0
17. A doctor prescribed sulphuric ointment for treating scab. Mark bases that must be used for it’s compounding in a pharmacy :
A * pork fat or emulsive basis
B beeswax or vaseline
C cacao butter or butyrolum
D soapily-glycerin or starched-glycerin
E lanolin or paraffin
18. A pharmacist prepares ointment by prescription : Rp.: Streptocidi 1,0 Vaselini 9,0 M. f. unq. D. S. For treatment of burns.
Specify the rational method of adding matter to basis:
A *to dispergate streptocide with 0,5 of molten vaseline
B to dispergate streptocide with 4,5 of molten vaseline
C to dispergate streptocide with 0,5 of unmolten vaseline
D to dispergate streptocide with 4,5 of unmolten vaseline
E to dispergate streptocide with 9,0 of molten vaseline
19. Pharmacy got a prescription : Rp: Xeroformii Picis Liquidae Betulae ana 3,0 Olei Ricini 100,0 M.D.S. For greasing of wounds.
Specify the type of medical form :
A * liniment
B ointment-emulsion
C paste
D combined ointment
E ointment-solution
20. It is necessary to prepare ointment with the matters that are soluble neither in basis nor in water in an amount over 5%. How is it needed to add them to basis?
A *to pound with part of the molten basis
B to pound with all unmolten basis
C to pound with part of the unmolten basis
D to pound with useful liquid
E to pound with alcohol-water-glyrerin mix
21. Pharmacy got a prescription for compounding Streptocide ointment without the indicated concentration. What concentration will a pharmacist prepare this ointment?
A * 10 %
B 5 %
C 1%
D 20 %
E 2 %
22. It is necessary to prepare 50,0 of Xeroformium ointment for a patient. What amount of Xeroformium was used by a pharmacist ?
A * 5,0
B 10,0
C 3,0
D 2,5
E 0,5
23. For preparation of ointment a pharmacist used paraffin additionally. Specify, what role is carried out by a paraffin in technology ?
A * gasket
B basis
C preservative
D for dispergating of powders
E emulsifier
24. A pharmacist prepares vaginal marbles on cacao butter with lemon acid in an amount less than 5%. Specify the rational method of introduction of matter into basis:
A * Dissolve in minimal quantity of water
B Dissolve in Dimexide
C Dissolve in molten cacao butter
D Dissolve in vaseline oil
E Dissolve in alcohol
25. Suppositories on butyrolum are prescribed. Specify the components of suppository basis :
A *Cacao butter , paraffin, hydrogenated fats
B Cacao butter , ozocerite, hydrogenated fats
C Cacao butter , cerezine, hydrogenated fats
D Cacao butter , beeswax, hydrogenated fats
E Cacao butter , petrolatum, hydrogenated fats
26. For preparation of suppositories different methods are used. They are deflation, outpouring, pressing. Specify basis for preparation of suppositories by the method of outpouring :
A * Butyrolum
B Paraffin
C Cacao butter
D Vaseline
E Coriander oil
27. A pharmacist prepared suppository mass with novocaine and cacao butter , but it became fragile. Specify a matter which must be added for formation of plastic mass :
A * Waterless lanolin
B Aquatic lanolin
C Paraffin
D Vaseline
E Beeswax
28. A pharmacist prepares rectal suppositories. Specify the possible limits of middle mass of these suppositories :
A * 1,0-4,0
B 2,0-5,0
C 3,0-6,0
D 4,0-7,0
E 5,0-8,0
29. A pharmacist prepares vaginal suppositories. Specify the possible limits of middle mass of these suppositories :
A * 1,5-6,0
B 1,0-4,0
C 2,0-6,5
D 3,0-7,0
E 4,0-7,5
30. Suppositories are prepared by different methods. Specify the method of preparation of rectal suppositories on cacao butter :
A * Rolling out
B Tabletting
C Granulation
D Outpouring
E Extracting
31. A pharmacist prepares rectal suppositories on Vitepsolum. Specify a liquid which it is necessary to use for wiping of suppository form :
A * Soap alcohol
B Vaseline oil
C Alcohol
D Water
E Apricot oil
32. Doctor prescribed suppositories of purgative action on soapily-glycerin basis. Specify the components of basis :
A * Glycerin, sodium carbonate, stearin acid
B Oil, water, glycerin
C Sodium carbonate, water, stearin acid
D Stearin acid, glycerin, water
E Water, sodium carbonate, glycerin
33. A pharmacist prepares rectal suppositories on polyaethylenoxide basis. Specify a liquid which it is necessary to use for wiping of suppository form :
A * Vaseline oil
B Alcohol
C Soap alcohol
D Water
E Dimexidum
34. Pharmacist compounded suspensive Wishnevsky liniment. Specify the method of adding Xeroformium:
A *To grind, to mix with half-amount of turpentine.
B To frind with alcohol.
C To grind, to mix with all amount of turpentine.
D To dissolve in all amount of oil.
E To grind, to mix with oil.
35. Doctor prescribed ointment of surface action on hydrofobic basis. Spacify this basis:
A *Vaseline
B Wax
C Cacao butter
D Spermaceti
E Bentonitum
36. Doctor prescribed suppositories without indicating basis. Specify the basis for compounding suppositories by the method of rolling out:
A *Cacao butter
B Lasupolum
C Lanolum
D Gelatin-glycerine
E Butyrolum
37. Pharmacist dissolved medicinal matter in warm basis at 400С. Choose the fat-soluble matter:
A *Mentholum
B Dermatolum
C Xeroformium
D Salicylic acid
E Novocainum
38. It is needed to prepare Wishnevsky liniment for a patient. What matters can be used as basis of liniment following the requirements of normative documents?
A * Castor oil or cod-liver oil.
B Sunflower or cotton oil.
C Camphorated or henbane oil.
D Vaseline oil or vaseline.
E Vaseline or lanolin.
39. A patient that needs camphorated ointment appealed to the pharmacy. What concentration ointment must pharmacist prepare following the requirements of normative documents?
A * 10 %.
B 20 %.
C 15 %.
D 5 %.
E 1 %.
40. A patient that needs zinc paste appealed to the pharmacy. What is the feature of introduction of zinc oxide?
A * Grind down with the molten basis.
B Grind down with starch and glycerin.
C Grind down with ether.
D Grind down with alcohol.
E Grind down with starch and molten basis.
41. 50 gs of zinc ointment are prepared for a patient. What amount of zinc and vaseline must pharmacist weigh out?
A * 5,0 gs and 45,0 gs
B 10,0 gs and 40,0 gs
C 2,5 gs and 47,5 gs
D 1,0 gs and 49,0 gs
E 0,5 gs and 49,5 gs
42. It is needed to prepare rectal suppositories for a patient by the method of outpouring. Specify hydrophilic basis for such suppositories.
A * Polyaethylenoxyde.
B Cacao butter.
C Butyrolum.
D Lasupolum.
E Vitepsolum.
43. Urethral sticks are prepared for the patient. Specify what parameters must doctor mark in the prescription for possibility of calculation of amount of basis.
A * Diameter, length and amount of sticks.
B Diameter and amount of sticks.
C Amount and length of sticks.
D Diameter of sticks and type of basis.
E Type of basis and amount of sticks.
44. Rosental liniment is prescribed to a patient. What components are there in it?
A * Paraffin, alcohol, chloroform, iodine.
B Castor oil, calcium chloride, alcohol.
C Chloroform, methylsalicylate, turpentine.
D Iodine, potassium iodide, glycerin.
E Sunflower oil, solution of ammonia, oleinic acid
45. Ointment for nose with Protargolum is prepared for a patient. How should be Protargolum added to ointment basis?
A * At first to pound with glycerin, and then with water.
B To grind up with water or alcohol.
C To grind up with alcohol or with ether.
D At first to pound with basis, and then with glycerin
E To pour on water.
46. Medicinal matters are added to ointments depending on their properties. How should be novocaine added to lanoline-vaseline basis ?
A * To dissolve preliminary in minimal quantity of water.
B To grind up with glycerin.
C To grind up with alcohol or with ether.
D To pound with part of the molten basis.
E To dissolve in the molten basis.
47. Lipophilic bases are used for compounding ointments. Specify the lipophilic component of bases that is hydrocarbons.
A * Paraffin.
B Esilonum - 4.
C Spermaceti.
D Combinations of fat.
E Phytosterol.
48. Rectal suppositories with 0,1 gr of Euphyllinum are compounded for the patient by the method of deflation. Specify the amount of basis for one suppository.
A * 2,9
B 3,9
C 2,4
D 1,9
E 1,4
49. A pharmacist prepared ointment: Rp.: Cerae flavae 4,0 Cetacei 3,0 Lanolini anhydrici 18,0 Olei Amygdalari 35,0 M. f. ung. D. S.: Ointment for hands.
What is the order of aaloying matters at making of ointment-alloy?
A * beeswax - spermaceti - lanolin - almond oil
B almondoil - spermaceti - beeswax - lanolin
C almond oil - beeswax - lanolin - spermaceti
D lanolin - beeswax – almond oil - spermaceti
E lanolin – beeswax – spermaceti - almond oil
50. A pharmacist prepared Kutumova emulsive basis. What emulsifier did he use?
A * Т- 2
B Twin - 80
C Solution of Methylcellulose
D Spen- 80
E Waterless lanolin
51. A pharmacist prepares ointment on hydrophobic basis. What matter will he use for the decline of temperature of melting of basis?
A * Vaseline oil
B Glycerine
C PEG- 400
D Dimexidum
E Ethanol
52. A pharmacist prepares ointment on hydrophobic basis. What matter will he use for the increase of temperature of melting and viscidity of basis?
A * Paraffin
B Waterless lanolin
C Vaseline
D Naphthalan oil
E Pork fat
53. A pharmacist prepares suspensive ointment. What matter is a well water-soluble, but should be added by the type of suspension to dermatological ointments?
A * Rezorcinum
B Zinc oxide
C Sulfacylum sodium
D Furacilinum
E Potassium iodide
54. Rectal suppositories with 0,1 gr of Euphyllinum are compounded in a pharmacy by the method of deflation. Specify the amount of basis for compounding 10 suppositories
A * 29,0
B 30,0.
C 28,0.
D 30,5.
E 19,5
55. Pharmacist compounded dermatologic paste. How did he add medicinal matters to the paste?
A *Grinded with half-amount of molten base in warm morter
B Mixed with glycerine in the mortar and added molten base
C Dispersed with alcohol in a warm mortar and mixed with basis
D Grinded with a suitable liquid in a warm mortar
E Grinded and mixed with basis in warm morta
56. The form of rectal suppositories is not indicated in the prescription. What is the optimal form for rectal suppositories?
A *Torpedo
B Marbles
C Ovulas
D Pessaries
E Bacillus
57. At compounding ointment with Protargolum a pharmacist assumed an error at introduction to the ingredient to basis. How is it necessary to add Protargolum to basis ?
A *to pound with glycerin, then with water
B to pound in a mortar with vaseline
C to pound with vaseline oil
D to pound in a mortar with water
E to pound with lanolin
58. A pharmacist prepared medicine by the prescription:
Rp.: Chloroformii
Olei Helianthi
Methylii salicylatis ana 10,0
M. D. S. For embrocation.
Specify the type of the dispersible system :
A * Liniment-solution
B Liniment-combined
C Liniment-emulsion
D Liniment-suspension
E Liniment-extraction
59. A pharmacist prepared medicine by the prescription:
Rp.: Picis liquidae Betulae
Хeroformi ana 6,0
Olei Ricini 100,0
Misce. Da. Signa. Wishnevsky balsam liniment.
Specify the type of the dispersible system :
A * Liniment-suspension
B Combined liniment
C Liniment-emulsion
D Liniment-solution
E Liniment-extraction
60. A pharmacist prepared medicine by the prescription:
Rp.: Olei Helianthi 7,4
Solutionis Ammonii caustici 2,5 ml
Асіdi oleinici 0,1
M. D. S :. Ammoniac liniment. For embrocations
Specify the type of the dispersible system :
A * Liniment-emulsion
B Combined liniment
C Liniment-solution
D Liniment-suspension
E Liniment-extraction
61. A pharmacist prepared medicine by the prescription:
Rp.: Streptocidi
Dermatoli of ana 1,0
Lanolini
Vaselini ana 5,0
M.D. S.: To inflict on the staggered areas of skin
Specify the type of the dispersible system :
A * Ointment-suspension
B Ointment-solution
C Ointment-emulsion
D Combined ointment
E Ointment-extraction
62. A pharmacist prepared medicine by the prescription:
Rp.: Dimedroli 0,3
Solutionis Adrenalini hydrochloridi gtts. ХХХ
Lanolini 5,0
Vaselini 10,0
M. D. S.: Ointment for a nose
Specify the type of the dispersible system :
A * Ointment-emulsion
B Ointment-solution
C Ointment-suspension
D Combined ointment
E Ointment-extraction
63. Pharmacist compounded suppositories of the mass 3,0 grs. Spesify the form of suppositories:
A * Torpedo
B Marbles
C Ovulas
D Pessaries
E Bacillus
64. Pharmacy got prescription for compounding oily liniment with streptocide. Specify type of disperse system of this medicinal form:
A * Suspensive
B Emulsive
C Solution
D Alloy
E Combined
65. Pharmacist changed Xeroformium at compounding Wishnevsky liniment. Specify the matter he had taken instead of Xeroformium:
A * Dermatolum
B Anaesthesinum
C Camphora
D Zinc oxide
E Novocainum
66. A pharmacist compounded ointment of surface action. Specify the basis that should be taken:
A * Vaseline
B Lanolinum
C Basis of Kutumova
D Gelatin-glycerine basis
E Polyaethylenoxide basis
67. Pharmacy got prescription for compounding ointment. Specify the methof of adding more then 5% of water-soluble matters to ointments:
A * To add by the type of suspension with a part of molten base
B To dissolve in water
C To dissolve in molten base
D To dissolve in suitable liquid
E To add at the end to the ointment
68. Pharmacist compounded suppositories by the method of rolling out. Specify the methof of addind Novocaine in an amount less then 5 %:
A * To dissolve in minimal amount of water.
B To add as fine powder.
C To add to molten basis.
D To dissolve in suitable liquid.
E To dissolve in vaseline oil.
69. Doctor didn’t indicated the basis for suppositories compounding. What basis did pharmacist choose:
A *Cacao butter
B Butyrolum
C Hydrogenated fat
D Polyaethylenoxide basis
E Gelatin-glycerine basis
70. A pharmacist prepared the combined ointment. Specify the order of compounding:
A * Suspension - solution - emulsion.
B Solution - emulsion - suspension.
C Emulsion - suspension - solution.
D Solution - suspension - emulsion.
E Emulsion - solution - suspension
71. Specify the basis that can be used for preparation of suppositories by the method of deflation:
A *Cacao butter.
B Vaseline.
C Butyrolum.
D Gelatin-glycerine.
E Lasupolum.
72. Suppositories with Belladonna extract are compounded in a pharmacy. Specify the method of adding Belladonna to suppository mass:
A *Solution of dense extract.
B Dry extract.
C Dense extract.
D Tincture.
E Decoction.
73. A pharmacist prepared ointment: Rp.: Tannini 0,2 Lanolini 3,0 Vaselini 10,0 M. ut f. ung. D.S. To put on skin. Specify the method of introduction of Tanninum:
A *To dissolve in water, to emulsify by waterless lanolin.
B To grind in a mortar by Deryagin rule with vaseline oil.
C To dissolve in molten vaseline.
D To grind in a mortar with alcohol and to mix up with basis.
E To dissolve in vaseline oil.
74. A pharmacist prepares dermatological ointment. Specify a matter that should be added to ointment basis as aquatic solution:
A * Protargolum;
B Starch;
C Camphor;
D Zinc oxide;
E Mentholum
75. A pharmacist compounded ointment: Rp: Zinci of oxydi 1,0 Vaselini 10,0 M.D.S. To inflict on skin.
What type does the ointment basis belong to?
A * Hydrophobic.
B Hydrophilic.
C Emulsive
D Lyophobic
E Oil and water sensitive
76. A pharmacist prepares ointment with 1 % of novocaine. How should be novocaine added to hydrophobic basis.
A * to dissolve in water, to emulsify with waterless lanolin
B to dissolve in alcohol, to add vaseline
C to grind up with vaseline oil, to add vaseline
D to grind up with alcohol or ether, to emulsify with waterless lanolin
E to grind up with glycerin, to add vaseline
77. A pharmacist compounded liniment: Rp.: Linimenti ammoniati 50,0 Mentholi 0,5 M. D. S. To grind into back.
What type of the dispersible system does it form?
A * Combined liniment
B Emulsive liniment w/o
C Liniment-alloy
D Emulsive liniment o/w
E Liniment-solution
78. A pharmacist compounded 10 rectal suppositories with 5,0 of Theophyllinum by the method of the hand forming. Specify the amount of cacao butter:
A * 25,0.
B 30,0
C 5,0
D 35, 0
E 40,0
79. Ointments with extracts are compounded in pharmacies. How should be extracts added to ointments:
A To pre-grind with alcohol-water-glycerine mix [1:6:3]
B To add to molten basis
C To pre-dissolve in water
D To disperse with suitable liquid
E To disperse with alcohol
80. By the method of compounding Naphthalan ointment belongs to:
A Ointments - alloys
B Ointments - solutions
C Extractive ointments
D Ointments - emulsions
E Ointments - suspensions
81. A pharmacist compounded suspensive ointment:
Rp.: Zinci of oxydi 5.0 Uaselini 45.0 M.D.S.: To rub into skin.
What method did hy use at dispersion of zinc oxide:
A To disperse with half-amount of molten basis
B To disperse with vaseline oil [2,5 grs]
C To disperse with plant oil [2,5 grs]
D To disperse with glycerine [2,5 grs]
E To disperse in warm mortar with 45,0 grs of molten basis
82. A pharmacist prepared ointment, intended for causing on an open wound surface. Specify an additional requirement such ointment must meet:
A * sterility
B isotonicity
C isoviscosity
D isoionity
E prolonged action
83. A pharmacist prepares extraction ointment. Specify a component that should be used for preparation to ointment of such type :
A * flowers of calendula
B tincture of calendula
C leaf of aloe
D extract of foxglove
E rutins
84. At preparation of liniment-solution pharmacist measured water to the vial, weighed out linen oil in even amounts and shook up intensively. Estimate the rightness of the chosen technology :
A * technology is correct, meets the requirements of preparation of liniments-solutions
B technology is wrong, because liniment should be prepared in a mortar
C technology is wrong, because linen oil should be measured by volume
D technology is wrong, because the prepared liniment should be filtered
E technology is wrong, because the prepared liniment should be sterilized
85. At preparation of suppositories by the method of deflation after introduction Chlorali hydras to cacao butter, suppository mass became bundle and began to spread. What matter should be added to suppository mass for proceeding in closeness and plasticity :
A * beeswax
B glycerin
C water
D dimexide
E starch
86. It is necessary to prepare ointment with osmotic activity. Specify the basis that should be used:
A * PEO- 400 6 parts, PEO-4000 4 parts
B vaseline
C vaseline 9 parts, waterless lanolin 1 part
D vaseline 6 parts, emulsifier Т-2 1 part, water 3 parts
E pork fat
87. What medicine should be added by the suspensive type at compounding dermatological ointments:
A * Xeroformium
B Camphor
C Mentholum
D Protargolum
E Ephedrine hydrochloride
88. A pharmacist prepared cream for the massage of such composition : Beeswax 12,0 Almond oil 68,5 Spermacetum 12,0 Waterless lanolin 7,5 Essential oil of lavender 3 drops. Specify the type of cream :
A * fatty
B nonfat
C emulsive
D suspensive
E combined
89. Among soft medications for local application oleogels are used. Specify the obligatory component of oleogels:
A * vaseline oil
B water
C tragacanth
D starch
E gelatin
90. It is necessary to prepare suppositories on gelatin-glycerine basis. Specify the technology of basis for such suppositories:
A * to add purified water to gelatin and abandon for swelling for 30-40 min, whereupon add glycerin and heat on an aquatic bath-house to formation of transparent homogeneous mass.
B to dissolve gelatin in hot water, to add glycerin and to mix
C to dissolve gelatin in glycerin, to add purified water, to mix
D to mix water with glycerin and to dissolve gelatin
E to dissolve gelatin in minimal quantity of alcohol, to add water and glycerin
91. What role is carried out by waterless lanolin in the composition of suppository mass at compounding suppositories by the method of deflation?
A * plasticizer
B solvent
C preservative
D solubilizer
E emollients
92. Pharmacy got different ointment bases. What type of ointment bases does polyaethylenoxyde belong to?
A *Hydrophilic
B Fatty
C Silicone
D Oil and water sensitive
E Hydrocarbon
93. A pharmacist compounds ointment on fatty basis. What type of ointment will Mentholum form?
A Ointment - solution
B Ointment - suspension
C Ointment - emulsion
D Extractive ointment
E Ointment - alloy
94. Pharmacist compounds ammonia (volatile) liniment. Spasify the matters it consists of:
A Acidum oleinicum, sunflower oil, 10 % solution of ammonia
B Acidum oleinicum, vaseline oil, 10 % solution of ammonia
C Acidum oleinicum, castor oil, 10 % solution of ammonia
D Novocainum, chloroform, Mentholum, sunflower oil, 10 % solution of ammonia
E Chloroform, turpentine, sunflower oil
95. Pharmacist compounds suppositories by the method of outpouring. Specify the conversion factor from fatty basis to gelatin-glycerine?
A *1,21
B 1,20
C 1,31
D 1,11
E 1,25
96. A pharmacist compounded ointment by dissolving one of the components in water after pregrinding it with glycerine. Specify this matter:
A *Protargolum
B Mentholum
C Streptocide
D Ichthyolum
E Dermatolum
97. It is necessary to prepare camphorated ointment:
Rp.: Camphorae 10,0 Vaselini 60,0 Lanolini anhydrici 30,0 Misce, fiat unguentum Da. Signa. For grindings
Specify, how should be camphor added to ointment?
A *to dissolve in fusion of vaseline and lanolin at 45-50° С
B to dissolve in minimal quantity of vaseline oil, then to mix up with vaseline and lanolin
C to dissolve in purified water, to emulsify by waterless lanolin , to mix up with vaseline
D to pound with vaseline, to add lanolin
E to pound with lanolin, to add vaseline
98. Pharmacist got aprescription:
Rp.: Bismuthi subnitratis 0,4 Vaselini 10,0
How should be medicinal matter added to ointment?
A *to pound with the half-amount of vaseline oil, to add vaseline
B to pound with the half-amount of molten vaseline, to add other vaseline
C to dissolve in basis
D to dissolve in water, to mix up with vaseline
E to pound carefully with all basis
99. What amount of basis should be used for preparation of this medicine:
Rp.: Anaesthesini 0,1 Xeroformii 0,5 Olei Cacao q. s. ut fiant suppositoria
numero 10 Da. Signa. 1 suppository per day rectally
A *24,0
B 25,0
C 30,0
D 36,0
E 40,0
100. A pharmacist prepares suppositories with Chlorali hydras. What is the feature of preparation of suppositories with this medicinal matter?
A *it is necessary to add gasket at generous amounts of Chlorali hydras
B waterless lanolin should always be added
C Chlorali hydras should be added as aquatic solution
D Chlorali hydras should be dissolved in alcohol-water-glycerine mix
E Chlorali hydras should be added as suspension
101. For mixing of aquatic solutions of medicinal matters with ointment basis such emulhator is mostly used:
A * Waterless lanolin;
B Twins;
C Spens;
D Gelatosa;
E Soap of alkaline metals.
102. It is necessary to prepare Rosental liniment in a pharmacy.
Rp.: Iodi 1,0
Kalii iodidi 2,0
Paraffini 20,0
Spiritus aethylici 70% 20 ml
Chloroformi 130,0
M. D. S.:
Specify the optimal method of dissolution of iodine at compounding such liniment.
A * To dissolve potassium iodide in the expected amount of purified water, to dissolve iodine in the saturated solution of potassium iodide , to add 95% alcohol
B To dissolve iodine in 70% alcohol
C To dissolve potassium iodide in 70% alcohol, to dissolve iodine in the saturated solution of potassium iodide
D To dissolve iodine in chloroform
E To add iodine in the end to prepared liniment
103. Soft medication on the basis of inorganic gel should be compounded in a pharmacy. Specify HMM that is possible to be applied for making basis.
A * Bentonites
B Ethers of cellulose
C Starch
D Polyaethylenoxydes
E Collogen
104. Emulsive ointment w/o with high maintenance of aquatic phase should be compounded in a pharmacy. Specify the optimal base for such ointment.
A *Vaseline + 50% of waterless lanolin
B Water lanolin
C Vaseline
D Hydrogenated fat
E Consistency emulsive basis
105. Suppositories on gelatin-glycerine basis are compounded in a pharmacy. Specify the amount of this basis comparing to fatty that should be used:
A * 1,21 times more
B Identical amount
C 2,5 times more
D 2 times more
E 3 times less
106. What basis should be taken for preparation of suppositories by the method of rolling out?
A * Cacao butter ;
B Butyrolum;
C Gelatin-glycerine basis;
D Vaseline;
E Mixture of vaseline with lanolin.
107. In a pharmacy it is necessary to prepare suppositories by the method of outpouring on gelatin-glycerine basis. What correlation of gelatin, water and glycerin shoud be taken for preparation of basis?
A * 1:2:5;
B 2:2:4;
C 1:3:4;
D 2:1:5;
E 3:2:3.
108. Choose the most optimal technology of preparation of this medical form (ointment-emulsion) : Rp.: Protargoli 1,0 Lanolini 3,0 Vaselini 12,0 M. f. ung. D. S.: To inflict on the mucous membrane of nose.
A * To grind protargolum with 6-8 drops of glycerin, to dissolve in 0,9 of purified water; to emulsify by 2,1 gr of waterless lanolin, to mix up with vaseline;
B To grind protargolum to shallow powder, to add melted vaseline, in the end to add lanolin;
C To melt vaseline with lanolin, to add drounded protargolum;
D To dissolve protargolum in water, to add vaseline and lanolin;
E To grind protargolum with a few drops of alcohol, to add the alloy of lanolin with vaseline.
109. What vaginal medical forms are compounded in pharmaceutic practice?
A * Pessaries;
B Vaginal pills;
C Vaginal capsules;
D Vaginal suds;
E Pills for preparation of vaginal solutions and suspensions.
110. What type of liniments does this prescription belong to: Rp.: Ol. Helianthi 7,4 Sol. Ammonii of caustici 25 ml of Ac. Oleinici 0,1 M.f. linimentum D.S. For embrocation.
A * Liniment-emulsion w/o
B Combined liniment
C Liniment-solution
D Liniment-suspension
E Emulsive liniment o/w
111. A pharmacist prepared ointment with Mentholum. Specify basis with which a matter forms ointment-solution
A * Vaselinum
B Collogen basis
C Methylcellulose gel
D Polyaethylenoxyde basis
E Phytosterine basis
112. A pharmacist prepares rectal suppositories on cacao butter with Dimedrolum in an amount less than 5%. Specify the rational method of introduction of matter in basis:
A * Dissolve in minimal quantity of purified water
B Dissolve in olive oil
C Dissolve in melted cacao butter
D Dissolve in vaseline oil
E Dissolve in alcohol
STERILE AND ASEPTICALLY-PREPARED MEDICINAL FORMS
1. Pharmacist compounded solution of Novocainum for injections. Choose the stebilizator:
A Solution of hydrochloric acid
B Solution of Sodium hydrocarbonate
C Wejbel liquor
D Solution of Sodium sulfite
E Solution of Sodium thiosulfate
2. Pharmacist compounded solution for injections. Choose the sterilization method for glasses that are used for compounding of aseptic medicinal forms in thr pharmacies:
A *Dry heat
B Tindalization
C Autoclaving
D Chemical matters
E Ultraviolet
3. Pharmacist compounded solution of ascorbic acid for injections. Choose the used stabilizator:
A *Sodium sulfite
B 0,1М solution of hydrochloric acid
C Boric acid
D 0,1М solution of sodium hydroxide
E Wejbel stabilizator
4. Pharmacist compounded 10 ml of eye drops of 1 % solution of Atropini sulfas. Choose the amount of sodium chloride for isotoning (equivalent of Atropini sulfas by sodium chloride is 0,1):
A *0,08
B 1,0
C 0,04
D 4,0
E 0,05
5. Pharmacist compounded eye drops with Riboflavinum, Kalii iodidum and Acidum ascorbinicum. Choose the method of adding Kalii iodidum:
A *To add aseptically after sterilization
B To dissolve in the solution of Riboflavinum
C To add last to the measuring glass
D To dissolve in purified water and to sterilize
E To put first to the vial
6. Pharmacist sterilized solutions for injections in autoclave. Choose the method of sterilization control:
A *Thermotests
B Stabilizators
C Buffer solutions
D Isotoning matters
E Antioxidants
7. Solutions for intravenous injections are prepared in the pharmacy.What components is it forbidden to add to such solutions?
A *Preservatives
B Water for injections
C Solution of sodium chloride
D Isotonic solution of sodium chloride
E Sterile water for injections
8. Pharmacy got the prescription for compounding eye drops with 1 % solution of Pylocarpini hydrochloridum. What matter was used for ensuring isotonicity?
A *sodium chloride
B boric acid
C glucose
D sodium nitrate
E sodium sulfate
9. Pharmacist-technologist got the prescription for eye drops with Adrenalini hydrochloridum. What property of Adrenalini hydrochloridum should be used in technology?
A *Thermolability
B Low solubility in water
C Bad solubility in alcohol
D Thermostability
E Volatility
10. A pharmacist prepared eye drops with zinc sulfate. What matter should be used for providing isotonicity :
A *Sodium sulfate
B Glucosa
C Sodium nitrate
D Sodium sulfite
E Sodium chloride
11. A pharmacist prepared 100 ml of isotonic solution of sodium chloride. Specify a method of sterilization of the finished good :
A *steam
B air
C gas
D mechanical
E radiation
12. A pharmacist prepared 150 ml of 10% solution of glucose. Specify, what amount of Wejbel liquid did he add for stabilizing of this solution :?
A * 7,5ml
B 5ml
C 10ml
D 15ml
E 3ml
13. A pharmacist prepared injection solution of sodium hydrocarbonate. Specify the maximal volume of filling to the vial.
A * 80%
B 100%
C 50%
D 40%
E 30%
14. Pharmacy got prescription for preparation of oculentum on vaseline-lanolin basis. Specify the correlation of the components of ointment basis.
A * 9:1
B 1:1
C 5:1
D 8:2
E 7:3
15. A pharmacist prepared 100 ml of 10 % solution of glucose for injections. Specify the amount of glucose for preparation of this solution (wetness of glucose - 10%)?
A *11,1
B 10,0
C 10,5
D 5,0
E 5,5
16. Pharmacy got prescription for preparation of eye drops with Protargolum. Specify the matter for isotoning eye drops.
A *do not isotone
B sodium chloride
C sodium nitrate
D sodium sulfate
E boric acid
17. A pharmacist prepared eye drops with silver nitrate. What matter should be taken for providing isotonicity?
A * Sodium nitrate
B Sodium chloride
C Boric acid
D Glucosa
E Sodium sulfate
18. Specify time of sterilization of 250 ml of 5% glucose by a pair force-feed at the temperature of 1200С?
A * 12 min
B 8 min
C 30 min
D 15 min
E 1 hour
19. A pharmacist prepared solution for injections with the salt of strong basis and weak acid. Specify a necessary stabilizator.
A * sodium hydroxide
B sodium sulfate
C hydrochloric acid
D ascorbic acid
E cystein
20. A pharmacist prepares solution for injections with a matter which needs stabilizing by 0,1 M solution of hydrochloric acid. Specify this matter:
A * Novocaine
B Calcium chloride
C Potassium chloride
D Hexamethylenetetramine
E Sodium benzoate
21. A pharmacist prepared injection solution with addition of stabilizator - sodium hydrocarbonate. Specify a matter which needs the use of this stabilizator :
A * Sodium thiosulphate
B Novocaine
C Ephedrine hydrochloride
D Sodium chloride
E Glucosa
22. A pharmacist prepared injection solution, with the use of stabilizator - 0,1 M solution of sodium hydroxide. Specify a matter which needs the use of this stabilizator :
A * Caffeine sodium benzoate
B Dibazolum
C Sodium hydrocarbonate
D Sodium chloride
E Glucosa
23. A pharmacist prepared injection solution from easily oxidizing matter which needs stabilizing by antioxidant. Specify this matter:
A * Ascorbic acid
B Dimedrol
C Sodium chloride
D Urotropinum
E Calcium gluconate
24. A pharmacist needs to sterilize 400 ml of injection solution of calcium gluconate. Specify time of sterilization of solution in an autoclave at the temperature of 1200 С :
A * 12 min
B 20 min
C 15 min
D 10 min
E 30 min
25. The solution-concentrate of riboflavin (1:5000) is used for making eye drops. Specify, what amount of solution must be measured off, if it is prescribed 0,001 of riboflavin:
A * 5 ml
B 2 ml
C 3 ml
D 4 ml
E 1 ml
26. It is necessary to prepare an yellow mercury oculentum. Specify optimal technology:
A * Matter is ground with vaseline oil, sterile vaseline and lanolin are added
B Matter is dissolved in water, sterile vaseline and lanolin are added
C Matter is ground with the molten sterile basis
D Matter is ground with glycerin, basis is added
E Matter is ground with alcohol, sterile vaseline and lanolin are added
27. Oculentum with Norsulfazolum-natrium is prescribed. Specify optimal ointment basis:
A * Alloy of vaseline with paraffin (6:4)
B Alloy of vaseline with lanolin (9:1)
C Emulsive basis of type o/w
D Alloy of vaseline with lanolin (7:3)
E Alloy of vaseline with paraffin (8:2)
26. It is necessary to prepare eye drops with pilocarpine hydrochloride. Specify optimal isotoning agent:
A * Sodium chloride
B Sodium sulfate
C Glucosa
D Boric acid
E Sodium nitrite
27. Pharmacist compounded eye drops with easily-soluble medicinal matter. Specify the volume of water for dissolving:
A * 1/2
B all volume
C 1/3
D 1/4
E 3/4
28. Pharmacy got prescription for compounding injection solution. Specify the matter that can not be sterilized:
A *Hexamethylentetraminum
B Novocaine
C Glucosa
D Calcii chloride
E Dibazolum
29. Pharmacist compounded eye drops with Pylocarpini hydrochloride and solution of Adrenalini hydrochloride. Specify the method of adding solution of Adrenalini hydrochloride:
A *To add aseptically after sterilization
B To add after dissolving dry matters
C To add to half-amount of solvent
D To add first
E To add after isotoning
30. Pharmacist compounded Wejbel stabilizer. Specify it’s composition:
A Sodium chloride and solution of hydrochloric acid
B Solution of hydrochloric acid
C Sodium hydrocarbonate and solution of boric acid
D Solution of sodium hydroxide
E Solution of boric acid and sodium tetraborate
31. It is needed to prepare injection solution with termolable matters. What optimal method of sterilization should pharmacist use?
A * Sterile filtration through a membrane filter.
B In an autoclave by the saturated pair force-feed.
C Sterilization by ultraviolet rays.
D Sterilization by dry heat.
E Radiation sterilization.
32. Methods of sterilization, which are used for preparation of medications in the conditions of asepsis can be divided into physical, mechanical, chemical. Specify the method of sterilization which belongs to chemical.
A * Addition of preservatives.
B Sterilization by dry heat.
C Radiation sterilization.
D Sterilization by pair force-feed.
E Sterilization by UV-rays.
33. For achievement of isotonicity of solutions a few methods of calculation of isotonic concentrations are used. Specify the method of calculation, which is most often accepted in pharmacy practice.
A * With the use of equivalents by sodium chloride.
B By law of Vant-Hoff.
C Graphic method.
D By law of Raul.
E By equalization of Mendeleev-Clapeiron.
34. It is needed to prepare eye drops with riboflavin. What matter should be added to solution to provide it’s isotonicity?
A * Sodium chloride.
B Sodium sulfate.
C Boric acid.
D Glucosa.
E Sodium nitrate.
35. It is needed to prepare injection solution of sodium of chloride 10%. What optimal method of sterilization should be used?
A * In an autoclave by the saturated pair force-feed.
B Sterile filtration through a membrane filter.
C Sterilization by gases.
D Sterilization by dry heat.
E Radiation sterilization.
36. Injection solutions of novocaine 0,25% and 0,5% are compounded. What does the volume of hydrochloric acid depend on?
A * The concentration of solution of novocaine.
B The mode of sterilization of solutions of novocaine.
C The sequence of adding of components in solutions.
D The sequence of operations of technological process.
E The cleanness of novocaine.
37. Solutions of sodium chloride for injections or unfusions are compounded. Specify additional requirements for quality of sodium chloride for infusion solution.
A * Ch.p., depyrogenized.
B P.f. a.
C Sort "for injections"
D The absence of admixtures of salts of manganese.
E Waterless, p.f.a.
39. 5% solutions of sodium hydrocarbonate for injections are compounded. Specify an optimal temperature at which it is possible to dissolve sodium hydrocarbonate avoiding strong interfusion.
A * 15-20 0С.
B 30-45 0С.
C 25-35 0С.
D 80-100 0С.
E 45-55 0С.
40. 2% infusion solution of glucoseis compounded. Specify an auxiliary matter which is applied for providing of isotonicity of this solution.
A * Sodium chloride.
B Sodium nitrate.
C Sodium sulfate.
D Sodium sulfite.
E Boric acid.
41. It is needed to prepare eye drops with Sulfacyl-sodium of the prolonged action. What matter can a doctor prescribe for prolongation of their action ?
A * Polyvinile alcohol.
B Gelatin.
C Glucosa
D PEO- 400.
E Sodium chloride.
42. It is needed to prepare an oculentum with pilocarpine hydrochloride. How should be pilocarpine hydrochloride added?
A * to dissolve in sterile water.
B to pound with sterile vaseline oil.
C to pound with sterile basis.
D to pound with sterile vaseline.
E to dissolve in the molten basis.
43. Infusion solutions are compounded. Specify the solution which is the regulator of aquatic-salt exchange :
A * Ringer-Lock solution
B Polyhybrid
C Hemodez Neo
D Hydrolysinum
E Dextrane
44. In obedience to the prescription 100 ml of 0,9% solution of sodium chloride is compounded. What is the mode of sterilization of this solution?
A *120 *С - 8 min
B 120 *С - 12 min
C 120* С - 15 min
D 180* С- of 30 min
E 100* С-15 min
45. Before preparation of isotonic solution of sodium chloride a pharmacist heated the powder in a dry-heat shelf. For the removal of what matters was this operation carried out?
A * of pyrogeneous matters
B of recuperative matters
C of sulfates
D of chlorides
E of moisture
46. Pharmacy got prescription on eye drops with Protargolum. What mode of sterilization must be chosen by pharmacist?
A * solution should not be sterilized
B by fluid pair
C by autoclaving
D by UV-rays
E by dry heat
47. Pharmacist compounds the solution of termolable matter. Spesify the optimal mode of sterilization:
A Sterile filtration through a membrane filter.
B Dry heat sterilization
C Sterilization by UV-rays
D Sterilization by fluid pair
E Sterilization by autoclaving
48. Eye drops of the prolonged action with Aethylmorphine hydrochloride are prepared. What auxiliary matter was added by a pharmacist for providing of the prolonged action of drops?
A *Methylcellulose.
B Starch.
C Gelatin.
D Arabian tragacanth.
E Dextrane.
49. A pharmacist prepared eye drops with Boric acid. What method of sterilization did he apply?
A *Sterilization by the saturated pair force-feed.
B Tindalisation.
C Sterilization by dry heat
D Sterilization by gases.
E Sterilization by UV-rays.
50. Pharmacist compounded eye drops with Laevomycetinum. Specify the mode of sterilization.
A Fluid pair
B Tindalisation
C Pasterisation
D By dry heat
E By the saturated pair
51. Pharmacist compounded basis for eye ointments. Specify the method of starilization?
A *By Dry heat
B Fluid pair
C Pasterisation
D UV-rays
E Membrane filtration
52. A pharmacist prepares injection solution of sodium thiosulphate. What stabilizator should be used?
A * Sodium hydrocarbonate
B Hydrochloric acid
C Sodium sulfite
D Ascorbic acid
E Wejbel stabilizator
53. Regulators of aquatic-salt exchange are used in medical practice. Specify solution which belongs to this group :
A * Solution of Ringer-Lock
B Solution of novocaine
C Solution "Hemodez Neo”
D Solution of glucose
E Solution "Polydez"
54. Pharmacist compounded solution of novocaine. Specify the mode of it’s sterilization:
A * Autoclaving
B Pasterisation
C Tindalisation
D Dry heat
E Ultrasound
55. Pharmacist compounded Glucosa solution. Specify the matter for it’s isotoning:
A * Sodium chloride
B Sodium sulfite
C Sodium bisulfite
D Sodium salicylate
E Sodium benzoate
56. A pharmacist needs to starilize 50 ml of solution of sodium chloride for injections by a fluid pair. Specify duration of sterilization :
A *30 min
B 60 min
C 12 min
D 15 min
E 8 min
57. It is necessary to prepare stable solution for injections with the matters which oxidize easily. Specify, what stabilizator did he add:
A * Sodium sulfite, sodium metabisulfite
B Hydrochloric acid.
C Sodium hydrocarbonate
D Sodium hydroxide.
E Sodium chloride.
58. It is necessary to add a stabilizator at preparation of solution of atropine sulfate for injections. Specify, what stabilizator should be added:
A *Hydrochloric acid.
B Sodium hydroxide.
C Sodium hydrocarbonate.
D Sodium metabisulfite.
E Ascorbic acid.
59. Pharmacy got prescription for compounding oculentum with Zinc sulfate. Specify the correct method of adding Zinc sulfate :
A *Dissolve in the half-volume of water.
B Grind with glycerin.
C Grind down with a suitable liquid.
D Grind with part of molten basis.
E Grind down with the weighed out basis.
60. A pharmacist is compounded powders: Rp.: Benzylpenicyllini - natrii 100 000 ED; Streptocidi 2,0; Misce fiat pulv. D.S. For blown.
Specify the amount of antibiotic if 1 mln ED is equal to 0,6 grs:
A * 0,06 gs
B 0,18 gs
C 2,0 gs
D 1,2 gs
E 1,8 gs
61. Ointment basis - alloy of vaseline and lanolin is used for preparation of oculentums. Specify the method of it’s sterilization:
A *by dry heat
B by oxide of aethylen
C by fluid pair
D pasterisation
E tindalisation
62. Injection solutions are compounded in the conditions of pharmacy. What solution is prepared without addition of stabilizator?
A *Sodium hydrocarbonate.
B Sodium thiosulphate.
C Caffeine-benzoate of sodium.
D Glucose.
E Novocaine.
63. Injection solutions of glucose after preparation should be sterilized:
A *Immediately.
B Not later than 1 hour.
C Not later than 2 hours.
D Not later than 3 hours.
E Not later than 5 hours.
64. Eye drops are compounded in the conditions of pharmacy. Specify the solution that shoud be not isotoned.
A * Collargol
B Pilocarpine hydrochloride
C Laevomycetine
D Riboflavin
E Cytralum
65. Oculentums are prepare in a pharmacy. Specify, what dispersible system if formed by adding Rezorcine to pharmakopoeian eye basis?
A *Emulsive.
B Suspensive.
C Solution.
D Alloy.
E Combined.
66. Pharmacy got prescription for preparation of dermatological ointment with Benzylpenicyllinum. Specify the type of the prepared ointment.
A Ointment-suspension
B Ointment-solution
C Ointment-emulsion
D Ointment-alloy
E Combined
67. Stabilization of injection solution of Novocaine is held for:
A Prevention of hydrolysis of the salt of strong acid and weak base
B Prevention of oxidation processes
C Prevention of hydrolysis of the salt of weak acid and strong base
D Prevention of hydrolysis of the salt of weak acid and weak base
E For better solubility of Novocaine
68. Specify, what objects need aseptic terms of making with next thermal sterilization by the saturated pair force-feed:
A * solutions for injections with termostable matters
B solutions for injections with termolable matters
C the concentrated solutions for the burette system
D liquid medications with antibiotics for internal application
E 2% solution of Collargolum for babies
69. A pharmacist prepared eye drops with Dicaine. What matter shoud be used for isotoning?
A * sodium chloride
B sodium sulfate
C sodium nitrate
D boric acid
E methylcellulose
70. With the purpose of providing sterility of eye drops preservatives are added to them. Specify what matter is metalorganic preservative:
A * mertyolatum
B boric acid
C benzyl alcohol
D sodium chloride
E sodium bromide
71. A pharmacist prepared eye drops with Trypsinum. What method provides sterility of drops?
A * preparation in aseptic terms, without next thermal sterilization
B sterilization by fluid pair
C sterilization by UV-rays
D radiation sterilization
E sterilization by saturated pair force-feed
72. Eye drops must be isotonic. Specify what matter should be used for isotoning of eye drops with collargolum?
A * glucose
B sodium chloride
C sodium sulfate
D sodium nitrate
E boric acid
73. An oculentum with rezorcinum is prepared. Specify the type of the dispersible system which is formed by Rezorcinum at adding to officinal eye basis.
A * emulsion
B suspension
C solution
D alloy
E combined
74. At preparation of oculentums an important value has a degree of dispersion of medicinal matters. Specify what medicinal matter should be preliminary carefully grinded with sterile vaseline oil?
A * Mercury yellow oxide
B Rezorcinum
C Pilocarpine hydrochloride
D Zinc sulfate
E Aethylmorphine hydrochloride
75. Pharmacist compounds some solutions with antibiotics in aseptic conditions. Spesify the solution that can be sterilized:
A *Laevomycetinum
B Benzylpenicyllinum-sodium
C Neomycine sulfate
D Benzylpenicyllinum-potassium
E Polymixinum sulfate
76. It is needed to prepare isotonic solution of sodium chloride for injections. How should pharmacist prepare a medicinal matter before preparation of solution?
A *heat in a dry-air sterilizer at 180° С during 2 hours
B dry up in a dry-air sterilizer at 100° С during 30 minutes
C sterilize in an autoclave at 120° С during 8 minutes
D sterilize in a dry-air sterilizer at 150° С during 1 hour
E sterilize in an autoclave at 120° С during 12 minutes
77. Pharmacy got prescription:
Rp.: Solutionis Zinci sulfatis 0,25% 20 ml Natrii sulfatis q. s., ut fiat solutio isotonica Da. Signa. 2 drops in both eyes 3 times per day.
Specify the optimal variant of technology.
A * to dissolve dry matters in 10 ml of water for injections, to filter to a vial through sterile preliminary washed foldfilter and cotton wool, to wash a filter by other water for injections
B to dissolve dry matters in 20 ml of water for injections, to filter to a vial through sterile preliminary washed foldfilter and cotton wool
C to dissolve dry matters in 20 ml of water for injections, to filter to a vial through a sterile dry foldfilter and cotton wool
D to dissolve dry matters in 20 ml of water for injections in a vial
E to pound dry matters in a sterile mortar with the half-amount of water for injections, to add other water, to carry to a vial
78. It is needed to prepare an oculentum by prescription: Rp.: Benzylpenicillini - natrii 250000 ED Basis pro oculi 10,0 Misce, ut fiat unguentum Da. Signa. To mortgage for an eyelid.
Specify, how is it necessary to add antibiotic to basis?
A * to pound with part of molten basis, to mix up with the other amount of basis
B to dissolve in molten basis
C to dissolve in minimal quantity of water for injections, to emulsify by waterless lanolin, to mix up with the basis
D to pound with vaseline oil, to mix up with basis
E to pound with the half-amount of water for injections, to mix up with basis
79. A pharmacist must prepare sodium hydrocarbonate 3 % - 200 ml for injections. What is the feature of technology of this solution?
A * filling vial on to 2/3 of volume and sterilization at 1200С - 12 min;
B no sterilization;
C dissolving at heating and sterilization at 1200С - 12 min;
D adding stabilizator;
E using water that is free of restoration matters.
80. A Pharmacist-technologist got a prescription on compounding of medical form for a 5 years old child with drastic matter. What principles should he follow at verification of dose of matter?
A * to differentiate a dose depending on age or mass of child;
B to take 1/2 doses adult;
C to take 1/4 doses adult;
D to take 1/12 doses adult;
E to take 3/4 doses adult.
81. Solutions of novocaine are compounded in pharmacy. Specify the type of the dispersible system which is formed at making of such solution.
A * Ion-dispersible
B Molecular-disperse
C Colloid solution
D Suspension
E Emulsion
82. 200 ml of 5 % solution of calcium chloride is made. Specify the volumes of solution of calcium chloride 50 % (1:2) and water that are necessary for compounding of this solution .
A * 20 ml and 180 ml
B 20 ml and 200 ml
C 50 ml and 150 ml
D 100 ml and 100 ml
E 180 ml and 20 ml
83. Solutions for injections with medicinal matters that oxidize easily are compounded. Specify an antioxidant that is line.
A * Sodium metabisulfite
B Tetacine
C Trilonum B
D Lemon acid
E Tiourea
84. Injection solutions must be pyrogen-free. Specify the solution that is possible to be depyrodenated by the method of adsorption with the use of absorbent carbon.
A *Solution of glucose
B Solution of atropine sulfate
C Solution of papaverine hydrochloride
D Solution of Scopolaminum hydrobromide
E Solution of Platyphyllinum hydrotartrate
85. Infusion solutions are compounded in a pharmacy. What matter is added to these solutions with the purpose of providing of vital functions of organism cells and creation of necessary redox?
A * Glucosa
B Sugar
C Starch
D Sodium chloride
E Sodium hydrocarbonate
86. What matter should be added to infusion solutions with close to blood viscidity?
A *Dextrane
B Glucosa
C Sodium chloride
D Sugar syrup
E Glycerin
87. Oculentum with zinc sulfate is compounded. Specify the type of the dispersible system which is formed at adding zinc sulfate to eye basis.
A * Emulsion
B Suspension
C Solution
D Alloy
E Combined
88. Pharmacy use vaseline of sort "for oculentums" for making oculentums. Specify the sign that differs it from ordinary vaseline.
A * Absence of restoration matters
B Absence of irritating action
C Firmness to the action of factors of external environment
D Indifference
E Color and smell
89. Specify the auxiliary matter that pharmacist can use at preparation of injection solutions as an antioxidant:
A * Ascorbic acid;
B Hydrochloric acid;
C Sodium hydrocarbonate;
D Sodium chloride;
E Wejbel solution.
90. Specify the matter that can be$ used as a chemical test for control of temperature condition of work of steam sterilizer at 121-122°С:
A * Benzoic acid;
B Antipyrine;
C Rezorcinum;
D Urea;
E Barbitalum.
91. Pharmacy got prescription on preparation of 2500 ml of isotonic solution of sodium chloride. Expect how many sodium chloride and water for injections is it necessary to take for preparation of this medical form :
A * 22,5 gs of sodium chloride and to 2500 ml of water for injections;
B 50,0 gs of sodium chloride and 2450 ml of water for injections;
C 25,0 gs of sodium chloride and 2500 ml of water for injections;
D 30,0 gs of sodium chloride and 2500 ml of water for injections;
E 100,0 gs of sodium chloride and 2400 ml of water for injections.
92. What distinguishes water for injections from purified water?
A * Apyrogenity;
B Value of рН;
C Absence of the mechanical including;
D Absence of heavy metals;
E Method of receipt.
93. What group of auxiliary matters does polyvinile alcoholbelong to?
A * Prolongers
B Preservatives
C Regulators of рН
D Antioxidants
E Isotoners
94. For making 1000 ml of 5 % solution of glucose Wejbel stabilizator is used in an amount:
A * 50 ml
B 100 ml
C 10 ml
D 20 ml
E 25 ml
95. What is the reason of instability of solutions of caffeine benzoate of sodium for injections?
A * Hydrolysis (salt of strong basis and weak acid)
B Hydrolysis (salt of strong acid and weak basis)
C Easy oxidizing of solution
D Caramelization of solution
E Reaction of neutralization
96. A pharmacist needs to sterilize 250 ml of injection solution of glucose. Specify the mode of sterilization of solution in an autoclave at a temperature 120 0C:
A * 12 minutes
B 8 minutes
C 15 minutes
D 25 minutes
E 30 minutes
97. A pharmacist makes ointment in aseptic terms on sterile basis - alloy of vaseline and lanolin in correlation of 6:4 and adds a matter by the type of suspension. Specify what matter is added:
A * Benzylpenicyllinum- sodium
B Sodium chloride
C Thiaminum chloride
D Pilocarpine hydrochloride
E Sodium sulfate
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