Chapter 2 Pulmonary Drug Metabolism, Clearance, and Absorption

The physicochemical properties of inhaled drugs vary considerably, from very hydrophilic to very hydrophobic (log P from −2 for the b 2-agonist salbutamol Fig. 2.1 Possible routes of elimination of drug from the lungs. Pulmonary drug metabolism, clearance, and absorption depend on an interplay between factors occurring prior to target inter- ................
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