OPTIMAL DOSAGE AND ROUTE OF ADMINISTRATION OF …
APPENDIX 1
Systematic search strategy Medline
APPENDIX 2
Oxford Centre for Evidence-based Medicine Levels of Evidence
|Level |Evidence (Therapeutic studies) |
| | |
|1 |Systematic review of RCTs |
| |Individual RCT (high quality) |
| | |
|2 |Systematic review of cohort studies |
| |Individual cohort study or lower quality RCT* |
| | |
|3 |Systematic review of case-control studies |
| |Individual case-control study |
| | |
|4 |Case-series and poor quality cohort and case-control studies |
| | |
|5 |Expert opinion |
*e.g. ................
................
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