Lippincott Williams & Wilkins
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ADDIN EN.CITE.DATA [2]Light vs. Deep SedationTreggiari ADDIN EN.CITE <EndNote><Cite><Author>Treggiari</Author><Year>2010</Year><RecNum>1931</RecNum><DisplayText>[3]</DisplayText><record><rec-number>1931</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232814">1931</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Treggiari, Miriam</author></authors></contributors><titles><title>Randomized trial of light versus deep sedation on mental health after critical illness</title><secondary-title>Crit. Care Med.</secondary-title></titles><periodical><full-title>Crit. Care Med.</full-title></periodical><pages>349-350</pages><volume>38</volume><number>1</number><dates><year>2010</year><pub-dates><date>2010/1</date></pub-dates></dates><isbn>0090-3493</isbn><urls><related-urls><url> Papers/T/Treggiari 2010 - Randomized trial of light versus deep sedation on mental health after critical illness.pdf</url></pdf-urls></urls><electronic-resource-num>10.1097/CCM.0b013e3181c546f8</electronic-resource-num></record></Cite></EndNote>[3]Shehabi PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5TaGVoYWJpPC9BdXRob3I+PFllYXI+MjAxMzwvWWVhcj48
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ADDIN EN.CITE.DATA [5]Light vs. Deep Sedation Treggiari ADDIN EN.CITE <EndNote><Cite><Author>Treggiari</Author><Year>2009</Year><RecNum>1725</RecNum><DisplayText>[6]</DisplayText><record><rec-number>1725</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232802">1725</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Treggiari, Miriam M.</author><author>Romand, Jacques-André</author><author>Yanez, N. David</author><author>Deem, Steven A.</author><author>Goldberg, Jack</author><author>Hudson, Leonard</author><author>Heidegger, Claudia-Paula</author><author>Weiss, Noel S.</author></authors></contributors><auth-address>University of Washington, Seattle, WA, USA. treggmm@u.washington.edu</auth-address><titles><title>Randomized trial of light versus deep sedation on mental health after critical illness</title><secondary-title>Crit. Care Med.</secondary-title></titles><periodical><full-title>Crit. Care Med.</full-title></periodical><pages>2527-2534</pages><volume>37</volume><number>9</number><keywords><keyword>PAD-ES Agitation/Sedation Manuscript</keyword></keywords><dates><year>2009</year><pub-dates><date>2009/9</date></pub-dates></dates><publisher>journals.</publisher><isbn>0090-3493</isbn><urls><related-urls><url> Papers/T/Treggiari et al. 2009 - Randomized trial of light versus deep sedation on mental health after critical illness.pdf</url></pdf-urls></urls><electronic-resource-num>10.1097/CCM.0b013e3181a5689f</electronic-resource-num></record></Cite></EndNote>[6]Tanaka PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5UYW5ha2E8L0F1dGhvcj48WWVhcj4yMDE0PC9ZZWFyPjxS
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ADDIN EN.CITE.DATA [2]Light vs. Deep Sedation Muller ADDIN EN.CITE <EndNote><Cite><Author>Muller</Author><Year>2008</Year><RecNum>1726</RecNum><DisplayText>[9]</DisplayText><record><rec-number>1726</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232802">1726</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Muller, L.</author><author>Chanques, G.</author><author>Bourgaux, C.</author><author>Louart, G.</author><author>Jaber, S.</author><author>Fabbro-Peray, P.</author><author>Ripart, J.</author><author>de La Coussaye, J. E.</author><author>Lefrant, J. Y.</author></authors></contributors><titles><title>Impact of the use of propofol remifentanil goal-directed sedation adapted by nurses on the time to extubation in mechanically ventilated ICU patients: The experience of a French ICU</title><secondary-title>Annales Fran?aises d'Anesthésie et de Réanimation</secondary-title></titles><periodical><full-title>Annales Fran?aises d'Anesthésie et de Réanimation</full-title></periodical><pages>481.e1-481.e8</pages><volume>27</volume><number>6</number><keywords><keyword>Sedation</keyword><keyword>ICU patientsés</keyword><keyword>Sédation</keyword><keyword>Réanimation</keyword><keyword>PAD-ES Agitation/Sedation Manuscript</keyword></keywords><dates><year>2008</year><pub-dates><date>2008</date></pub-dates></dates><publisher>Elsevier</publisher><isbn>0750-7658</isbn><urls><related-urls><url> Papers/M/Muller et al. 2008 - Impact of the use of propofol remifentanil goal-dir ... mechanically ventilated ICU patients - The experience of a French ICU.pdf</url></pdf-urls></urls></record></Cite></EndNote>[9]Treggiari ADDIN EN.CITE <EndNote><Cite><Author>Treggiari</Author><Year>2009</Year><RecNum>1725</RecNum><DisplayText>[6]</DisplayText><record><rec-number>1725</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232802">1725</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Treggiari, Miriam M.</author><author>Romand, Jacques-André</author><author>Yanez, N. David</author><author>Deem, Steven A.</author><author>Goldberg, Jack</author><author>Hudson, Leonard</author><author>Heidegger, Claudia-Paula</author><author>Weiss, Noel S.</author></authors></contributors><auth-address>University of Washington, Seattle, WA, USA. treggmm@u.washington.edu</auth-address><titles><title>Randomized trial of light versus deep sedation on mental health after critical illness</title><secondary-title>Crit. Care Med.</secondary-title></titles><periodical><full-title>Crit. Care Med.</full-title></periodical><pages>2527-2534</pages><volume>37</volume><number>9</number><keywords><keyword>PAD-ES Agitation/Sedation Manuscript</keyword></keywords><dates><year>2009</year><pub-dates><date>2009/9</date></pub-dates></dates><publisher>journals.</publisher><isbn>0090-3493</isbn><urls><related-urls><url> Papers/T/Treggiari et al. 2009 - Randomized trial of light versus deep sedation on mental health after critical illness.pdf</url></pdf-urls></urls><electronic-resource-num>10.1097/CCM.0b013e3181a5689f</electronic-resource-num></record></Cite></EndNote>[6]Bugedo PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5CdWdlZG88L0F1dGhvcj48WWVhcj4yMDEzPC9ZZWFyPjxS
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ADDIN EN.CITE.DATA [11]Light vs. Deep Sedation Treggiari ADDIN EN.CITE <EndNote><Cite><Author>Treggiari</Author><Year>2009</Year><RecNum>1725</RecNum><DisplayText>[6]</DisplayText><record><rec-number>1725</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232802">1725</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Treggiari, Miriam M.</author><author>Romand, Jacques-André</author><author>Yanez, N. David</author><author>Deem, Steven A.</author><author>Goldberg, Jack</author><author>Hudson, Leonard</author><author>Heidegger, Claudia-Paula</author><author>Weiss, Noel S.</author></authors></contributors><auth-address>University of Washington, Seattle, WA, USA. treggmm@u.washington.edu</auth-address><titles><title>Randomized trial of light versus deep sedation on mental health after critical illness</title><secondary-title>Crit. Care Med.</secondary-title></titles><periodical><full-title>Crit. Care Med.</full-title></periodical><pages>2527-2534</pages><volume>37</volume><number>9</number><keywords><keyword>PAD-ES Agitation/Sedation Manuscript</keyword></keywords><dates><year>2009</year><pub-dates><date>2009/9</date></pub-dates></dates><publisher>journals.</publisher><isbn>0090-3493</isbn><urls><related-urls><url> Papers/T/Treggiari et al. 2009 - Randomized trial of light versus deep sedation on mental health after critical illness.pdf</url></pdf-urls></urls><electronic-resource-num>10.1097/CCM.0b013e3181a5689f</electronic-resource-num></record></Cite></EndNote>[6], Strom ADDIN EN.CITE <EndNote><Cite><Author>Str?m</Author><Year>2011</Year><RecNum>2500</RecNum><DisplayText>[12]</DisplayText><record><rec-number>2500</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1508334149">2500</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Str?m, Thomas</author><author>Stylsvig, Mette</author><author>Toft, Palle</author></authors></contributors><titles><title>Long-term psychological effects of a no-sedation protocol in critically ill patients</title><secondary-title>Critical Care</secondary-title></titles><periodical><full-title>Critical Care</full-title></periodical><pages>R293</pages><volume>15</volume><number>6</number><dates><year>2011</year></dates><isbn>1364-8535</isbn><urls></urls></record></Cite></EndNote>[12]Propofol vs. Benzodiazepine – Cardiac SurgeryGrounds ADDIN EN.CITE <EndNote><Cite><Author>Grounds</Author><Year>1987</Year><RecNum>1704</RecNum><DisplayText>[13]</DisplayText><record><rec-number>1704</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232801">1704</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Grounds, R. M.</author><author>Lalor, J. M.</author><author>Lumley, J.</author><author>Royston, D.</author><author>Morgan, M.</author></authors></contributors><titles><title>Propofol infusion for sedation in the intensive care unit: preliminary report</title><secondary-title>Br. Med. J.</secondary-title></titles><periodical><full-title>Br. Med. J.</full-title></periodical><pages>397-400</pages><volume>294</volume><number>6569</number><keywords><keyword>PAD-ES Agitation/Sedation Manuscript</keyword></keywords><dates><year>1987</year><pub-dates><date>1987/2/14</date></pub-dates></dates><publisher></publisher><isbn>0267-0623</isbn><urls><related-urls><url> Papers/G/Grounds et al. 1987 - Propofol infusion for sedation in the intensive care unit - preliminary report.pdf</url></pdf-urls></urls></record></Cite></EndNote>[13], Snellen ADDIN EN.CITE <EndNote><Cite><Author>Snellen</Author><Year>1990</Year><RecNum>1734</RecNum><DisplayText>[14]</DisplayText><record><rec-number>1734</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232803">1734</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Snellen, F.</author><author>Lauwers, P.</author><author>Demeyere, R.</author><author>Byttebier, G.</author><author>Van Aken, H.</author></authors></contributors><auth-address>Department of Anaesthesiology, University Hospital, Gasthuisberg, Leuven, Belgium.</auth-address><titles><title>The use of midazolam versus propofol for short-term sedation following coronary artery bypass grafting</title><secondary-title>Intensive Care Med.</secondary-title></titles><periodical><full-title>Intensive Care Med.</full-title></periodical><pages>312-316</pages><volume>16</volume><number>5</number><keywords><keyword>PAD-ES Agitation/Sedation Manuscript</keyword></keywords><dates><year>1990</year><pub-dates><date>1990</date></pub-dates></dates><publisher>Springer</publisher><isbn>0342-4642</isbn><urls><related-urls><url> Papers/S/Snellen et al. 1990 - The use of midazolam versus propofol for short-term sedation following coronary artery bypass grafting.pdf</url></pdf-urls></urls></record></Cite></EndNote>[14], McMurray ADDIN EN.CITE <EndNote><Cite><Author>McMurray</Author><Year>1990</Year><RecNum>1737</RecNum><DisplayText>[15]</DisplayText><record><rec-number>1737</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232803">1737</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>McMurray, T. 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ADDIN EN.CITE.DATA [28]Propofol vs. Benzodiazepine – NON Cardiac SurgeryBoeke ADDIN EN.CITE <EndNote><Cite><Author>Boeke</Author><Year>1989</Year><RecNum>1911</RecNum><DisplayText>[20]</DisplayText><record><rec-number>1911</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232812">1911</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Boeke, A.</author><author>Lauwers, J.</author><author>Schurink, G.</author></authors></contributors><titles><title>A pilot study to compare the use of propofol and midazolam for long-term sedation</title><secondary-title>J Drug Dev</secondary-title></titles><periodical><full-title>J Drug Dev</full-title></periodical><pages>71-72</pages><volume>2</volume><number>suppl 2</number><dates><year>1989</year><pub-dates><date>1989</date></pub-dates></dates><urls></urls></record></Cite></EndNote>[20], Clarke ADDIN EN.CITE <EndNote><Cite><Author>Clarke</Author><Year>1991</Year><RecNum>2501</RecNum><DisplayText>[21]</DisplayText><record><rec-number>2501</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1508336286">2501</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Clarke, TNS</author></authors></contributors><titles><title>Propofol compared with midazolam for sedation following prolonged neurosurgery</title><secondary-title>Journal of Drug Development</secondary-title></titles><periodical><full-title>Journal of Drug Development</full-title></periodical><pages>108-108</pages><volume>4</volume><dates><year>1991</year></dates><isbn>0952-9500</isbn><urls></urls></record></Cite></EndNote>[21], Carrasco ADDIN EN.CITE <EndNote><Cite><Author>Carrasco</Author><Year>1993</Year><RecNum>1941</RecNum><DisplayText>[22]</DisplayText><record><rec-number>1941</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232814">1941</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Carrasco, G.</author><author>Molina, R.</author><author>Costa, J.</author><author>Soler, J. M.</author><author>Cabré, L.</author></authors></contributors><auth-address>Intensive Care Service, SCIAS-Hospital de Barcelona, Spain.</auth-address><titles><title>Propofol vs midazolam in short-, medium-, and long-term sedation of critically ill patients. A cost-benefit analysis</title><secondary-title>Chest</secondary-title></titles><periodical><full-title>Chest</full-title></periodical><pages>557-564</pages><volume>103</volume><number>2</number><dates><year>1993</year><pub-dates><date>1993/2</date></pub-dates></dates><isbn>0012-3692</isbn><urls><related-urls><url>(15)41482-5</url><url> Papers/C/Carrasco et al. 1993 - Propofol vs midazolam in short-, medium-, and long-term sedation of critically ill patients. A cost-benefit analysis.pdf</url></pdf-urls></urls></record></Cite></EndNote>[22], Costa ADDIN EN.CITE <EndNote><Cite><Author>Costa</Author><Year>1994</Year><RecNum>2024</RecNum><DisplayText>[23]</DisplayText><record><rec-number>2024</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232819">2024</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Costa, J.</author><author>Cabré, L.</author><author>Molina, R.</author><author>Carrasco, G.</author></authors></contributors><auth-address>Intensive Care Unit, SCIAS, Hospital de Barcelona, Spain.</auth-address><titles><title>Cost of ICU sedation: comparison of empirical and controlled sedation methods</title><secondary-title>Clin. Intensive Care</secondary-title></titles><periodical><full-title>Clin. Intensive Care</full-title></periodical><pages>17-21</pages><volume>5</volume><number>5 Suppl</number><dates><year>1994</year><pub-dates><date>1994</date></pub-dates></dates><isbn>0956-3075</isbn><urls><related-urls><url>;[23], Barrientos-Vega ADDIN EN.CITE <EndNote><Cite><Author>Barrientos-Vega</Author><Year>1997</Year><RecNum>1947</RecNum><DisplayText>[24]</DisplayText><record><rec-number>1947</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232815">1947</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Barrientos-Vega, R.</author><author>Mar Sánchez-Soria, M.</author><author>Morales-García, C.</author><author>Robas-Gómez, A.</author><author>Cuena-Boy, R.</author><author>Ayensa-Rincon, A.</author></authors></contributors><auth-address>Intensive Care Unit, Hospital Virgen de Salud, Toledo, Spain.</auth-address><titles><title>Prolonged sedation of critically ill patients with midazolam or propofol: impact on weaning and costs</title><secondary-title>Crit. Care Med.</secondary-title></titles><periodical><full-title>Crit. Care Med.</full-title></periodical><pages>33-40</pages><volume>25</volume><number>1</number><dates><year>1997</year><pub-dates><date>1997/1</date></pub-dates></dates><isbn>0090-3493</isbn><urls><related-urls><url>;[24], Hall 2001 ADDIN EN.CITE <EndNote><Cite><Author>Hall</Author><Year>2001</Year><RecNum>1948</RecNum><DisplayText>[25]</DisplayText><record><rec-number>1948</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232815">1948</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Hall, R. I.</author><author>Sandham, D.</author><author>Cardinal, P.</author><author>Tweeddale, M.</author><author>Moher, D.</author><author>Wang, X.</author><author>Anis, A. H.</author><author>Study, Investigators</author></authors></contributors><auth-address>Department of Anesthesia, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada. rihall@is.dal.ca</auth-address><titles><title>Propofol vs midazolam for ICU sedation : a Canadian multicenter randomized trial</title><secondary-title>Chest</secondary-title></titles><periodical><full-title>Chest</full-title></periodical><pages>1151-1159</pages><volume>119</volume><number>4</number><dates><year>2001</year><pub-dates><date>2001/4</date></pub-dates></dates><isbn>0012-3692</isbn><urls><related-urls><url>(15)52074-6</url><url> Papers/H/Hall et al. 2001 - Propofol vs midazolam for ICU sedation - a Canadian multicenter randomized trial.pdf</url></pdf-urls></urls></record></Cite></EndNote>[25], Mesnil ADDIN EN.CITE <EndNote><Cite><Author>Mesnil</Author><Year>2011</Year><RecNum>1945</RecNum><DisplayText>[26]</DisplayText><record><rec-number>1945</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232814">1945</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Mesnil, Malcie</author><author>Capdevila, Xavier</author><author>Bringuier, Sophie</author><author>Trine, Pierre-Olivier</author><author>Falquet, Yoan</author><author>Charbit, Jonathan</author><author>Roustan, Jean-Paul</author><author>Chanques, Gerald</author><author>Jaber, Samir</author></authors></contributors><auth-address>Department of Anesthesiology and Critical Care Lapeyronie (DAR A), Montpellier I University and Montpellier University Lapeyronie Hospital, Institut National de la Santé et de la Recherche Médicale (INSERM), Equipe soutenue par la Région et l'Inserm (ERI) -25, Route de Ganges, 34295 Montpellier, Cedex 5, France.</auth-address><titles><title>Long-term sedation in intensive care unit: a randomized comparison between inhaled sevoflurane and intravenous propofol or midazolam</title><secondary-title>Intensive Care Med.</secondary-title></titles><periodical><full-title>Intensive Care Med.</full-title></periodical><pages>933-941</pages><volume>37</volume><number>6</number><dates><year>2011</year><pub-dates><date>2011/6</date></pub-dates></dates><isbn>0342-4642</isbn><urls><related-urls><url> Papers/M/Mesnil et al. 2011 - Long-term sedation in intensive care unit - a rand ... ison between inhaled sevoflurane and intravenous propofol or midazolam.pdf</url></pdf-urls></urls><electronic-resource-num>10.1007/s00134-011-2187-3</electronic-resource-num></record></Cite></EndNote>[26], Srivastava PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5Tcml2YXN0YXZhPC9BdXRob3I+PFllYXI+MjAxNDwvWWVh
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ADDIN EN.CITE.DATA [28]Propofol vs. Benzodiazepine –NON Cardiac SurgeryCarson ADDIN EN.CITE <EndNote><Cite><Author>Carson</Author><Year>2006</Year><RecNum>1728</RecNum><DisplayText>[29]</DisplayText><record><rec-number>1728</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232803">1728</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Carson, Shannon S.</author><author>Kress, John P.</author><author>Rodgers, Jo Ellen</author><author>Vinayak, Ajeet</author><author>Campbell-Bright, Stacy</author><author>Levitt, Joseph</author><author>Bourdet, Sharya</author><author>Ivanova, Anastasia</author><author>Henderson, Ashley G.</author><author>Pohlman, Anne</author><author>Chang, Lydia</author><author>Rich, Preston B.</author><author>Hall, Jesse</author></authors></contributors><auth-address>Division of Pulmonary and Critical Care, Department of Medicine, University of North Carolina at Chapel Hill, 4134 Bioinformatics Building, Chapel Hill, NC 27599-7020, USA. scarson@med.unc.edu</auth-address><titles><title>A randomized trial of intermittent lorazepam versus propofol with daily interruption in mechanically ventilated patients</title><secondary-title>Crit. Care Med.</secondary-title></titles><periodical><full-title>Crit. Care Med.</full-title></periodical><pages>1326-1332</pages><volume>34</volume><number>5</number><keywords><keyword>PAD-ES Agitation/Sedation Manuscript</keyword></keywords><dates><year>2006</year><pub-dates><date>2006/5</date></pub-dates></dates><publisher>journals.</publisher><isbn>0090-3493</isbn><urls><related-urls><url>;[29], Zhou PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaG91PC9BdXRob3I+PFllYXI+MjAxNDwvWWVhcj48UmVj
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ADDIN EN.CITE.DATA [28]Propofol vs. Benzodiazepine – NON Cardiac SurgeryCarrasco ADDIN EN.CITE <EndNote><Cite><Author>Carrasco</Author><Year>1993</Year><RecNum>1941</RecNum><DisplayText>[22]</DisplayText><record><rec-number>1941</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232814">1941</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Carrasco, G.</author><author>Molina, R.</author><author>Costa, J.</author><author>Soler, J. M.</author><author>Cabré, L.</author></authors></contributors><auth-address>Intensive Care Service, SCIAS-Hospital de Barcelona, Spain.</auth-address><titles><title>Propofol vs midazolam in short-, medium-, and long-term sedation of critically ill patients. A cost-benefit analysis</title><secondary-title>Chest</secondary-title></titles><periodical><full-title>Chest</full-title></periodical><pages>557-564</pages><volume>103</volume><number>2</number><dates><year>1993</year><pub-dates><date>1993/2</date></pub-dates></dates><isbn>0012-3692</isbn><urls><related-urls><url>(15)41482-5</url><url> Papers/C/Carrasco et al. 1993 - Propofol vs midazolam in short-, medium-, and long-term sedation of critically ill patients. A cost-benefit analysis.pdf</url></pdf-urls></urls></record></Cite></EndNote>[22], Chamorro ADDIN EN.CITE <EndNote><Cite><Author>Chamorro</Author><Year>1996</Year><RecNum>1942</RecNum><DisplayText>[30]</DisplayText><record><rec-number>1942</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232814">1942</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Chamorro, C.</author><author>de Latorre, F. J.</author><author>Montero, A.</author><author>Sánchez-Izquierdo, J. A.</author><author>Jare?o, A.</author><author>Moreno, J. A.</author><author>Gonzalez, E.</author><author>Barrios, M.</author><author>Carpintero, J. L.</author><author>Martín-Santos, F.</author><author>Otero, B.</author><author>Ginestal, R.</author></authors></contributors><auth-address>Intensive Care Units, Clínica Puerta de Hierro, Madrid, Spain.</auth-address><titles><title>Comparative study of propofol versus midazolam in the sedation of critically ill patients: results of a prospective, randomized, multicenter trial</title><secondary-title>Crit. Care Med.</secondary-title></titles><periodical><full-title>Crit. Care Med.</full-title></periodical><pages>932-939</pages><volume>24</volume><number>6</number><dates><year>1996</year><pub-dates><date>1996/6</date></pub-dates></dates><isbn>0090-3493</isbn><urls><related-urls><url>;[30], Weinbroum ADDIN EN.CITE <EndNote><Cite><Author>Weinbroum</Author><Year>1997</Year><RecNum>1943</RecNum><DisplayText>[31]</DisplayText><record><rec-number>1943</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232814">1943</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Weinbroum, A. 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A.</author><author>Caballero-Cubedo, R. E.</author><author>Perez-Vela, J. L.</author><author>Ambros-Checa, A.</author><author>Cantalapiedra-Santiago, J. A.</author><author>Alted-Lopez, E.</author></authors></contributors><auth-address>Department of Intensive Care Medicine, Hospital Universitario 12 de Octubre, Madrid, Spain.</auth-address><titles><title>Propofol versus midazolam: safety and efficacy for sedating the severe trauma patient</title><secondary-title>Anesth. Analg.</secondary-title></titles><periodical><full-title>Anesth. Analg.</full-title></periodical><pages>1219-1224</pages><volume>86</volume><number>6</number><dates><year>1998</year><pub-dates><date>1998/6</date></pub-dates></dates><isbn>0003-2999</isbn><urls><related-urls><url> Papers/S/Sanchez-Izquierdo-Riera et al. 1998 - Propofol versus midazolam - safety and efficacy for sedating the severe trauma patient.pdf</url></pdf-urls></urls></record></Cite></EndNote>[32], Sandiumenge-Camps ADDIN EN.CITE <EndNote><Cite><Author>Sandiumenge Camps</Author><Year>2000</Year><RecNum>1944</RecNum><DisplayText>[33]</DisplayText><record><rec-number>1944</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232814">1944</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Sandiumenge Camps, A.</author><author>Sanchez-Izquierdo Riera, J. A.</author><author>Toral Vazquez, D.</author><author>Sa Borges, M.</author><author>Peinado Rodriguez, J.</author><author>Alted Lopez, E.</author></authors></contributors><auth-address>Department of Intensive Care Medicine, 12 de Octubre University Hospital, Madrid, Spain.</auth-address><titles><title>Midazolam and 2% propofol in long-term sedation of traumatized critically ill patients: efficacy and safety comparison</title><secondary-title>Crit. Care Med.</secondary-title></titles><periodical><full-title>Crit. Care Med.</full-title></periodical><pages>3612-3619</pages><volume>28</volume><number>11</number><dates><year>2000</year><pub-dates><date>2000/11</date></pub-dates></dates><isbn>0090-3493</isbn><urls><related-urls><url>;[33], Mesnil ADDIN EN.CITE <EndNote><Cite><Author>Mesnil</Author><Year>2011</Year><RecNum>1945</RecNum><DisplayText>[26]</DisplayText><record><rec-number>1945</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232814">1945</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Mesnil, Malcie</author><author>Capdevila, Xavier</author><author>Bringuier, Sophie</author><author>Trine, Pierre-Olivier</author><author>Falquet, Yoan</author><author>Charbit, Jonathan</author><author>Roustan, Jean-Paul</author><author>Chanques, Gerald</author><author>Jaber, Samir</author></authors></contributors><auth-address>Department of Anesthesiology and Critical Care Lapeyronie (DAR A), Montpellier I University and Montpellier University Lapeyronie Hospital, Institut National de la Santé et de la Recherche Médicale (INSERM), Equipe soutenue par la Région et l'Inserm (ERI) -25, Route de Ganges, 34295 Montpellier, Cedex 5, France.</auth-address><titles><title>Long-term sedation in intensive care unit: a randomized comparison between inhaled sevoflurane and intravenous propofol or midazolam</title><secondary-title>Intensive Care Med.</secondary-title></titles><periodical><full-title>Intensive Care Med.</full-title></periodical><pages>933-941</pages><volume>37</volume><number>6</number><dates><year>2011</year><pub-dates><date>2011/6</date></pub-dates></dates><isbn>0342-4642</isbn><urls><related-urls><url> Papers/M/Mesnil et al. 2011 - Long-term sedation in intensive care unit - a rand ... ison between inhaled sevoflurane and intravenous propofol or midazolam.pdf</url></pdf-urls></urls><electronic-resource-num>10.1007/s00134-011-2187-3</electronic-resource-num></record></Cite></EndNote>[26], Zhou PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaG91PC9BdXRob3I+PFllYXI+MjAxNDwvWWVhcj48UmVj
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ADDIN EN.CITE.DATA [28]Propofol vs. Benzodiazepine – NON Cardiac SurgeryMesnil 2011 ADDIN EN.CITE <EndNote><Cite><Author>Mesnil</Author><Year>2011</Year><RecNum>1945</RecNum><DisplayText>[26]</DisplayText><record><rec-number>1945</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232814">1945</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Mesnil, Malcie</author><author>Capdevila, Xavier</author><author>Bringuier, Sophie</author><author>Trine, Pierre-Olivier</author><author>Falquet, Yoan</author><author>Charbit, Jonathan</author><author>Roustan, Jean-Paul</author><author>Chanques, Gerald</author><author>Jaber, Samir</author></authors></contributors><auth-address>Department of Anesthesiology and Critical Care Lapeyronie (DAR A), Montpellier I University and Montpellier University Lapeyronie Hospital, Institut National de la Santé et de la Recherche Médicale (INSERM), Equipe soutenue par la Région et l'Inserm (ERI) -25, Route de Ganges, 34295 Montpellier, Cedex 5, France.</auth-address><titles><title>Long-term sedation in intensive care unit: a randomized comparison between inhaled sevoflurane and intravenous propofol or midazolam</title><secondary-title>Intensive Care Med.</secondary-title></titles><periodical><full-title>Intensive Care Med.</full-title></periodical><pages>933-941</pages><volume>37</volume><number>6</number><dates><year>2011</year><pub-dates><date>2011/6</date></pub-dates></dates><isbn>0342-4642</isbn><urls><related-urls><url> Papers/M/Mesnil et al. 2011 - Long-term sedation in intensive care unit - a rand ... ison between inhaled sevoflurane and intravenous propofol or midazolam.pdf</url></pdf-urls></urls><electronic-resource-num>10.1007/s00134-011-2187-3</electronic-resource-num></record></Cite></EndNote>[26] Dexmedetomidine vs. Benzodiazepine Riker ADDIN EN.CITE <EndNote><Cite><Author>Riker</Author><Year>2009</Year><RecNum>327</RecNum><DisplayText>[34]</DisplayText><record><rec-number>327</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232717">327</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Riker, Richard R.</author><author>Shehabi, Yahya</author><author>Bokesch, Paula M.</author><author>Ceraso, Daniel</author><author>Wisemandle, Wayne</author><author>Koura, Firas</author><author>Whitten, Patrick</author><author>Margolis, Benjamin D.</author><author>Byrne, Daniel W.</author><author>Ely, E. Wesley</author><author>Rocha, Marcelo G.</author><author>Sedcom Study Group</author></authors></contributors><titles><title>Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>489-499</pages><volume>301</volume><number>5</number><keywords><keyword>ICU Rehab 2016</keyword></keywords><dates><year>2009</year><pub-dates><date>2009/2/4</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url>;[34], Srivastava PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5Tcml2YXN0YXZhPC9BdXRob3I+PFllYXI+MjAxNDwvWWVh
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ADDIN EN.CITE.DATA [27], Pandharipande ADDIN EN.CITE <EndNote><Cite><Author>Pandharipande</Author><Year>2007</Year><RecNum>380</RecNum><DisplayText>[8]</DisplayText><record><rec-number>380</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232720">380</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Pandharipande, Pratik P.</author><author>Pun, Brenda T.</author><author>Herr, Daniel L.</author><author>Maze, Mervyn</author><author>Girard, Timothy D.</author><author>Miller, Russell R.</author><author>Shintani, Ayumi K.</author><author>Thompson, Jennifer L.</author><author>Jackson, James C.</author><author>Deppen, Stephen A.</author><author>Stiles, Renee A.</author><author>Dittus, Robert S.</author><author>Bernard, Gordon R.</author><author>Ely, E. Wesley</author></authors></contributors><titles><title>Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>2644-2653</pages><volume>298</volume><number>22</number><keywords><keyword>ICU Rehab 2016</keyword></keywords><dates><year>2007</year><pub-dates><date>2007/12/12</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url>;[8], Maclaren ADDIN EN.CITE <EndNote><Cite><Author>MacLaren</Author><Year>2013</Year><RecNum>2499</RecNum><DisplayText>[35]</DisplayText><record><rec-number>2499</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1508272294">2499</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>MacLaren, Robert</author><author>Krisl, Jill C</author><author>Cochrane, Rebecca E</author><author>Mueller, Scott W</author></authors></contributors><titles><title>A Case‐Based Approach to the Practical Application of Dexmedetomidine in Critically Ill Adults</title><secondary-title>Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy</secondary-title></titles><periodical><full-title>Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy</full-title></periodical><pages>165-186</pages><volume>33</volume><number>2</number><dates><year>2013</year></dates><isbn>1875-9114</isbn><urls></urls></record></Cite></EndNote>[35], Jakob ADDIN EN.CITE <EndNote><Cite><Author>Jakob</Author><Year>2012</Year><RecNum>1950</RecNum><DisplayText>[36]</DisplayText><record><rec-number>1950</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232815">1950</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Jakob, Stephan M.</author><author>Ruokonen, Esko</author><author>Grounds, R. Michael</author><author>Sarapohja, Toni</author><author>Garratt, Chris</author><author>Pocock, Stuart J.</author><author>Bratty, J. Raymond</author><author>Takala, Jukka</author><author>Dexmedetomidine for Long-Term Sedation, Investigators</author></authors></contributors><auth-address>Department of Intensive Care Medicine, Bern University Hospital and University of Bern, Bern, Switzerland.</auth-address><titles><title>Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>1151-1160</pages><volume>307</volume><number>11</number><dates><year>2012</year><pub-dates><date>2012/3/21</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url> Papers/J/Jakob et al. 2012 - Dexmedetomidine vs midazolam or propofol for sedati ... ng prolonged mechanical ventilation - two randomized controlled trials.pdf</url></pdf-urls></urls><electronic-resource-num>10.1001/jama.2012.304</electronic-resource-num></record></Cite></EndNote>[36]Dexmedetomidine vs. Benzodiazepine Pandharipande ADDIN EN.CITE <EndNote><Cite><Author>Pandharipande</Author><Year>2007</Year><RecNum>380</RecNum><DisplayText>[8]</DisplayText><record><rec-number>380</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232720">380</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Pandharipande, Pratik P.</author><author>Pun, Brenda T.</author><author>Herr, Daniel L.</author><author>Maze, Mervyn</author><author>Girard, Timothy D.</author><author>Miller, Russell R.</author><author>Shintani, Ayumi K.</author><author>Thompson, Jennifer L.</author><author>Jackson, James C.</author><author>Deppen, Stephen A.</author><author>Stiles, Renee A.</author><author>Dittus, Robert S.</author><author>Bernard, Gordon R.</author><author>Ely, E. Wesley</author></authors></contributors><titles><title>Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>2644-2653</pages><volume>298</volume><number>22</number><keywords><keyword>ICU Rehab 2016</keyword></keywords><dates><year>2007</year><pub-dates><date>2007/12/12</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url>;[8], Jakob ADDIN EN.CITE <EndNote><Cite><Author>Jakob</Author><Year>2012</Year><RecNum>1950</RecNum><DisplayText>[36]</DisplayText><record><rec-number>1950</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232815">1950</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Jakob, Stephan M.</author><author>Ruokonen, Esko</author><author>Grounds, R. Michael</author><author>Sarapohja, Toni</author><author>Garratt, Chris</author><author>Pocock, Stuart J.</author><author>Bratty, J. Raymond</author><author>Takala, Jukka</author><author>Dexmedetomidine for Long-Term Sedation, Investigators</author></authors></contributors><auth-address>Department of Intensive Care Medicine, Bern University Hospital and University of Bern, Bern, Switzerland.</auth-address><titles><title>Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>1151-1160</pages><volume>307</volume><number>11</number><dates><year>2012</year><pub-dates><date>2012/3/21</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url> Papers/J/Jakob et al. 2012 - Dexmedetomidine vs midazolam or propofol for sedati ... ng prolonged mechanical ventilation - two randomized controlled trials.pdf</url></pdf-urls></urls><electronic-resource-num>10.1001/jama.2012.304</electronic-resource-num></record></Cite></EndNote>[36], Riker ADDIN EN.CITE <EndNote><Cite><Author>Riker</Author><Year>2009</Year><RecNum>327</RecNum><DisplayText>[34]</DisplayText><record><rec-number>327</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232717">327</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Riker, Richard R.</author><author>Shehabi, Yahya</author><author>Bokesch, Paula M.</author><author>Ceraso, Daniel</author><author>Wisemandle, Wayne</author><author>Koura, Firas</author><author>Whitten, Patrick</author><author>Margolis, Benjamin D.</author><author>Byrne, Daniel W.</author><author>Ely, E. Wesley</author><author>Rocha, Marcelo G.</author><author>Sedcom Study Group</author></authors></contributors><titles><title>Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>489-499</pages><volume>301</volume><number>5</number><keywords><keyword>ICU Rehab 2016</keyword></keywords><dates><year>2009</year><pub-dates><date>2009/2/4</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url>;[34]Dexmedetomidine vs. Benzodiazepine Jakob ADDIN EN.CITE <EndNote><Cite><Author>Jakob</Author><Year>2012</Year><RecNum>1950</RecNum><DisplayText>[36]</DisplayText><record><rec-number>1950</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232815">1950</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Jakob, Stephan M.</author><author>Ruokonen, Esko</author><author>Grounds, R. Michael</author><author>Sarapohja, Toni</author><author>Garratt, Chris</author><author>Pocock, Stuart J.</author><author>Bratty, J. Raymond</author><author>Takala, Jukka</author><author>Dexmedetomidine for Long-Term Sedation, Investigators</author></authors></contributors><auth-address>Department of Intensive Care Medicine, Bern University Hospital and University of Bern, Bern, Switzerland.</auth-address><titles><title>Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>1151-1160</pages><volume>307</volume><number>11</number><dates><year>2012</year><pub-dates><date>2012/3/21</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url> Papers/J/Jakob et al. 2012 - Dexmedetomidine vs midazolam or propofol for sedati ... ng prolonged mechanical ventilation - two randomized controlled trials.pdf</url></pdf-urls></urls><electronic-resource-num>10.1001/jama.2012.304</electronic-resource-num></record></Cite></EndNote>[36], Xu ADDIN EN.CITE <EndNote><Cite><Author>Xu</Author><Year>2012</Year><RecNum>2139</RecNum><DisplayText>[37]</DisplayText><record><rec-number>2139</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232826">2139</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Xu, J. B.</author><author>Wang, Y. Z.</author><author>Shi, Q. S.</author></authors></contributors><titles><title>A combined protocol for dexmedetomidine used in prolonged sedation in intensive care unit</title><secondary-title>Modern Medicine Journal of China</secondary-title></titles><periodical><full-title>Modern Medicine Journal of China</full-title></periodical><pages>20-22</pages><volume>14</volume><number>12</number><dates><year>2012</year><pub-dates><date>2012</date></pub-dates></dates><urls></urls></record></Cite></EndNote>[37], Pandharipande ADDIN EN.CITE <EndNote><Cite><Author>Pandharipande</Author><Year>2007</Year><RecNum>380</RecNum><DisplayText>[8]</DisplayText><record><rec-number>380</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232720">380</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Pandharipande, Pratik P.</author><author>Pun, Brenda T.</author><author>Herr, Daniel L.</author><author>Maze, Mervyn</author><author>Girard, Timothy D.</author><author>Miller, Russell R.</author><author>Shintani, Ayumi K.</author><author>Thompson, Jennifer L.</author><author>Jackson, James C.</author><author>Deppen, Stephen A.</author><author>Stiles, Renee A.</author><author>Dittus, Robert S.</author><author>Bernard, Gordon R.</author><author>Ely, E. Wesley</author></authors></contributors><titles><title>Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>2644-2653</pages><volume>298</volume><number>22</number><keywords><keyword>ICU Rehab 2016</keyword></keywords><dates><year>2007</year><pub-dates><date>2007/12/12</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url>;[8], Riker ADDIN EN.CITE <EndNote><Cite><Author>Riker</Author><Year>2009</Year><RecNum>327</RecNum><DisplayText>[34]</DisplayText><record><rec-number>327</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232717">327</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Riker, Richard R.</author><author>Shehabi, Yahya</author><author>Bokesch, Paula M.</author><author>Ceraso, Daniel</author><author>Wisemandle, Wayne</author><author>Koura, Firas</author><author>Whitten, Patrick</author><author>Margolis, Benjamin D.</author><author>Byrne, Daniel W.</author><author>Ely, E. Wesley</author><author>Rocha, Marcelo G.</author><author>Sedcom Study Group</author></authors></contributors><titles><title>Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>489-499</pages><volume>301</volume><number>5</number><keywords><keyword>ICU Rehab 2016</keyword></keywords><dates><year>2009</year><pub-dates><date>2009/2/4</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url>;[34]Dexmedetomidine vs. Benzodiazepine Esmaoglu ADDIN EN.CITE <EndNote><Cite><Author>Esmaoglu</Author><Year>2009</Year><RecNum>2498</RecNum><DisplayText>[38]</DisplayText><record><rec-number>2498</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1508271733">2498</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Esmaoglu, Aliye</author><author>Ulgey, Ay?e</author><author>Akin, Aynur</author><author>Boyaci, Adem</author></authors></contributors><titles><title>Comparison between dexmedetomidine and midazolam for sedation of eclampsia patients in the intensive care unit</title><secondary-title>Journal of critical care</secondary-title></titles><periodical><full-title>Journal of critical care</full-title></periodical><pages>551-555</pages><volume>24</volume><number>4</number><dates><year>2009</year></dates><isbn>0883-9441</isbn><urls></urls></record></Cite></EndNote>[38], Jakob ADDIN EN.CITE <EndNote><Cite><Author>Jakob</Author><Year>2012</Year><RecNum>1950</RecNum><DisplayText>[36]</DisplayText><record><rec-number>1950</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232815">1950</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Jakob, Stephan M.</author><author>Ruokonen, Esko</author><author>Grounds, R. Michael</author><author>Sarapohja, Toni</author><author>Garratt, Chris</author><author>Pocock, Stuart J.</author><author>Bratty, J. Raymond</author><author>Takala, Jukka</author><author>Dexmedetomidine for Long-Term Sedation, Investigators</author></authors></contributors><auth-address>Department of Intensive Care Medicine, Bern University Hospital and University of Bern, Bern, Switzerland.</auth-address><titles><title>Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>1151-1160</pages><volume>307</volume><number>11</number><dates><year>2012</year><pub-dates><date>2012/3/21</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url> Papers/J/Jakob et al. 2012 - Dexmedetomidine vs midazolam or propofol for sedati ... ng prolonged mechanical ventilation - two randomized controlled trials.pdf</url></pdf-urls></urls><electronic-resource-num>10.1001/jama.2012.304</electronic-resource-num></record></Cite></EndNote>[36], Riker ADDIN EN.CITE <EndNote><Cite><Author>Riker</Author><Year>2009</Year><RecNum>327</RecNum><DisplayText>[34]</DisplayText><record><rec-number>327</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232717">327</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Riker, Richard R.</author><author>Shehabi, Yahya</author><author>Bokesch, Paula M.</author><author>Ceraso, Daniel</author><author>Wisemandle, Wayne</author><author>Koura, Firas</author><author>Whitten, Patrick</author><author>Margolis, Benjamin D.</author><author>Byrne, Daniel W.</author><author>Ely, E. Wesley</author><author>Rocha, Marcelo G.</author><author>Sedcom Study Group</author></authors></contributors><titles><title>Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>489-499</pages><volume>301</volume><number>5</number><keywords><keyword>ICU Rehab 2016</keyword></keywords><dates><year>2009</year><pub-dates><date>2009/2/4</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url>;[34], Pandharipande ADDIN EN.CITE <EndNote><Cite><Author>Pandharipande</Author><Year>2007</Year><RecNum>380</RecNum><DisplayText>[8]</DisplayText><record><rec-number>380</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232720">380</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Pandharipande, Pratik P.</author><author>Pun, Brenda T.</author><author>Herr, Daniel L.</author><author>Maze, Mervyn</author><author>Girard, Timothy D.</author><author>Miller, Russell R.</author><author>Shintani, Ayumi K.</author><author>Thompson, Jennifer L.</author><author>Jackson, James C.</author><author>Deppen, Stephen A.</author><author>Stiles, Renee A.</author><author>Dittus, Robert S.</author><author>Bernard, Gordon R.</author><author>Ely, E. Wesley</author></authors></contributors><titles><title>Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>2644-2653</pages><volume>298</volume><number>22</number><keywords><keyword>ICU Rehab 2016</keyword></keywords><dates><year>2007</year><pub-dates><date>2007/12/12</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url>;[8], Xu ADDIN EN.CITE <EndNote><Cite><Author>Xu</Author><Year>2012</Year><RecNum>2139</RecNum><DisplayText>[37]</DisplayText><record><rec-number>2139</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232826">2139</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Xu, J. B.</author><author>Wang, Y. Z.</author><author>Shi, Q. S.</author></authors></contributors><titles><title>A combined protocol for dexmedetomidine used in prolonged sedation in intensive care unit</title><secondary-title>Modern Medicine Journal of China</secondary-title></titles><periodical><full-title>Modern Medicine Journal of China</full-title></periodical><pages>20-22</pages><volume>14</volume><number>12</number><dates><year>2012</year><pub-dates><date>2012</date></pub-dates></dates><urls></urls></record></Cite></EndNote>[37]Dexmedetomidine vs. Benzodiazepine Esmaoglu ADDIN EN.CITE <EndNote><Cite><Author>Esmaoglu</Author><Year>2009</Year><RecNum>2498</RecNum><DisplayText>[38]</DisplayText><record><rec-number>2498</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1508271733">2498</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Esmaoglu, Aliye</author><author>Ulgey, Ay?e</author><author>Akin, Aynur</author><author>Boyaci, Adem</author></authors></contributors><titles><title>Comparison between dexmedetomidine and midazolam for sedation of eclampsia patients in the intensive care unit</title><secondary-title>Journal of critical care</secondary-title></titles><periodical><full-title>Journal of critical care</full-title></periodical><pages>551-555</pages><volume>24</volume><number>4</number><dates><year>2009</year></dates><isbn>0883-9441</isbn><urls></urls></record></Cite></EndNote>[38], Jakob ADDIN EN.CITE <EndNote><Cite><Author>Jakob</Author><Year>2012</Year><RecNum>1950</RecNum><DisplayText>[36]</DisplayText><record><rec-number>1950</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232815">1950</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Jakob, Stephan M.</author><author>Ruokonen, Esko</author><author>Grounds, R. Michael</author><author>Sarapohja, Toni</author><author>Garratt, Chris</author><author>Pocock, Stuart J.</author><author>Bratty, J. Raymond</author><author>Takala, Jukka</author><author>Dexmedetomidine for Long-Term Sedation, Investigators</author></authors></contributors><auth-address>Department of Intensive Care Medicine, Bern University Hospital and University of Bern, Bern, Switzerland.</auth-address><titles><title>Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>1151-1160</pages><volume>307</volume><number>11</number><dates><year>2012</year><pub-dates><date>2012/3/21</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url> Papers/J/Jakob et al. 2012 - Dexmedetomidine vs midazolam or propofol for sedati ... ng prolonged mechanical ventilation - two randomized controlled trials.pdf</url></pdf-urls></urls><electronic-resource-num>10.1001/jama.2012.304</electronic-resource-num></record></Cite></EndNote>[36], Riker ADDIN EN.CITE <EndNote><Cite><Author>Riker</Author><Year>2009</Year><RecNum>327</RecNum><DisplayText>[34]</DisplayText><record><rec-number>327</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232717">327</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Riker, Richard R.</author><author>Shehabi, Yahya</author><author>Bokesch, Paula M.</author><author>Ceraso, Daniel</author><author>Wisemandle, Wayne</author><author>Koura, Firas</author><author>Whitten, Patrick</author><author>Margolis, Benjamin D.</author><author>Byrne, Daniel W.</author><author>Ely, E. Wesley</author><author>Rocha, Marcelo G.</author><author>Sedcom Study Group</author></authors></contributors><titles><title>Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>489-499</pages><volume>301</volume><number>5</number><keywords><keyword>ICU Rehab 2016</keyword></keywords><dates><year>2009</year><pub-dates><date>2009/2/4</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url>;[34], Xu ADDIN EN.CITE <EndNote><Cite><Author>Xu</Author><Year>2012</Year><RecNum>2139</RecNum><DisplayText>[37]</DisplayText><record><rec-number>2139</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232826">2139</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Xu, J. B.</author><author>Wang, Y. Z.</author><author>Shi, Q. S.</author></authors></contributors><titles><title>A combined protocol for dexmedetomidine used in prolonged sedation in intensive care unit</title><secondary-title>Modern Medicine Journal of China</secondary-title></titles><periodical><full-title>Modern Medicine Journal of China</full-title></periodical><pages>20-22</pages><volume>14</volume><number>12</number><dates><year>2012</year><pub-dates><date>2012</date></pub-dates></dates><urls></urls></record></Cite></EndNote>[37]Dexmedetomidine vs. PropofolJakob ADDIN EN.CITE <EndNote><Cite><Author>Jakob</Author><Year>2012</Year><RecNum>1950</RecNum><DisplayText>[36]</DisplayText><record><rec-number>1950</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232815">1950</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Jakob, Stephan M.</author><author>Ruokonen, Esko</author><author>Grounds, R. Michael</author><author>Sarapohja, Toni</author><author>Garratt, Chris</author><author>Pocock, Stuart J.</author><author>Bratty, J. Raymond</author><author>Takala, Jukka</author><author>Dexmedetomidine for Long-Term Sedation, Investigators</author></authors></contributors><auth-address>Department of Intensive Care Medicine, Bern University Hospital and University of Bern, Bern, Switzerland.</auth-address><titles><title>Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>1151-1160</pages><volume>307</volume><number>11</number><dates><year>2012</year><pub-dates><date>2012/3/21</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url> Papers/J/Jakob et al. 2012 - Dexmedetomidine vs midazolam or propofol for sedati ... ng prolonged mechanical ventilation - two randomized controlled trials.pdf</url></pdf-urls></urls><electronic-resource-num>10.1001/jama.2012.304</electronic-resource-num></record></Cite></EndNote>[36], Herr ADDIN EN.CITE <EndNote><Cite><Author>Herr</Author><Year>2003</Year><RecNum>1953</RecNum><DisplayText>[39]</DisplayText><record><rec-number>1953</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232815">1953</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Herr, Daniel L.</author><author>Sum-Ping, S. T. John</author><author>England, Michael</author></authors></contributors><auth-address>Washington Hospital Center, Washington, DC 2010, USA. Daniel.L.Herr@</auth-address><titles><title>ICU sedation after coronary artery bypass graft surgery: dexmedetomidine-based versus propofol-based sedation regimens</title><secondary-title>J. Cardiothorac. Vasc. Anesth.</secondary-title></titles><periodical><full-title>J. Cardiothorac. Vasc. Anesth.</full-title></periodical><pages>576-584</pages><volume>17</volume><number>5</number><dates><year>2003</year><pub-dates><date>2003/10</date></pub-dates></dates><isbn>1053-0770</isbn><urls><related-urls><url> Papers/H/Herr et al. 2003 - ICU sedation after coronary artery bypass graft surgery - dexmedetomidine-based versus propofol-based sedation regimens.pdf</url></pdf-urls></urls></record></Cite></EndNote>[39], Srivastava PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5Tcml2YXN0YXZhPC9BdXRob3I+PFllYXI+MjAxNDwvWWVh
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ADDIN EN.CITE.DATA [27]Dexmedetomidine vs. PropofolJakob ADDIN EN.CITE <EndNote><Cite><Author>Jakob</Author><Year>2012</Year><RecNum>1950</RecNum><DisplayText>[36]</DisplayText><record><rec-number>1950</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232815">1950</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Jakob, Stephan M.</author><author>Ruokonen, Esko</author><author>Grounds, R. Michael</author><author>Sarapohja, Toni</author><author>Garratt, Chris</author><author>Pocock, Stuart J.</author><author>Bratty, J. Raymond</author><author>Takala, Jukka</author><author>Dexmedetomidine for Long-Term Sedation, Investigators</author></authors></contributors><auth-address>Department of Intensive Care Medicine, Bern University Hospital and University of Bern, Bern, Switzerland.</auth-address><titles><title>Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>1151-1160</pages><volume>307</volume><number>11</number><dates><year>2012</year><pub-dates><date>2012/3/21</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url> Papers/J/Jakob et al. 2012 - Dexmedetomidine vs midazolam or propofol for sedati ... ng prolonged mechanical ventilation - two randomized controlled trials.pdf</url></pdf-urls></urls><electronic-resource-num>10.1001/jama.2012.304</electronic-resource-num></record></Cite></EndNote>[36]Dexmedetomidine vs. PropofolJakob ADDIN EN.CITE <EndNote><Cite><Author>Jakob</Author><Year>2012</Year><RecNum>1950</RecNum><DisplayText>[36]</DisplayText><record><rec-number>1950</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232815">1950</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Jakob, Stephan M.</author><author>Ruokonen, Esko</author><author>Grounds, R. Michael</author><author>Sarapohja, Toni</author><author>Garratt, Chris</author><author>Pocock, Stuart J.</author><author>Bratty, J. Raymond</author><author>Takala, Jukka</author><author>Dexmedetomidine for Long-Term Sedation, Investigators</author></authors></contributors><auth-address>Department of Intensive Care Medicine, Bern University Hospital and University of Bern, Bern, Switzerland.</auth-address><titles><title>Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>1151-1160</pages><volume>307</volume><number>11</number><dates><year>2012</year><pub-dates><date>2012/3/21</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url> Papers/J/Jakob et al. 2012 - Dexmedetomidine vs midazolam or propofol for sedati ... ng prolonged mechanical ventilation - two randomized controlled trials.pdf</url></pdf-urls></urls><electronic-resource-num>10.1001/jama.2012.304</electronic-resource-num></record></Cite></EndNote>[36]Dexmedetomidine vs. PropofolJakob ADDIN EN.CITE <EndNote><Cite><Author>Jakob</Author><Year>2012</Year><RecNum>1950</RecNum><DisplayText>[36]</DisplayText><record><rec-number>1950</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232815">1950</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Jakob, Stephan M.</author><author>Ruokonen, Esko</author><author>Grounds, R. Michael</author><author>Sarapohja, Toni</author><author>Garratt, Chris</author><author>Pocock, Stuart J.</author><author>Bratty, J. Raymond</author><author>Takala, Jukka</author><author>Dexmedetomidine for Long-Term Sedation, Investigators</author></authors></contributors><auth-address>Department of Intensive Care Medicine, Bern University Hospital and University of Bern, Bern, Switzerland.</auth-address><titles><title>Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>1151-1160</pages><volume>307</volume><number>11</number><dates><year>2012</year><pub-dates><date>2012/3/21</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url> Papers/J/Jakob et al. 2012 - Dexmedetomidine vs midazolam or propofol for sedati ... ng prolonged mechanical ventilation - two randomized controlled trials.pdf</url></pdf-urls></urls><electronic-resource-num>10.1001/jama.2012.304</electronic-resource-num></record></Cite></EndNote>[36]Dexmedetomidine vs. PropofolJakob ADDIN EN.CITE <EndNote><Cite><Author>Jakob</Author><Year>2012</Year><RecNum>1950</RecNum><DisplayText>[36]</DisplayText><record><rec-number>1950</rec-number><foreign-keys><key app="EN" db-id="v9razzrwmtv29zeet5tvadzm9d5dffdd0s55" timestamp="1507232815">1950</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Jakob, Stephan M.</author><author>Ruokonen, Esko</author><author>Grounds, R. Michael</author><author>Sarapohja, Toni</author><author>Garratt, Chris</author><author>Pocock, Stuart J.</author><author>Bratty, J. Raymond</author><author>Takala, Jukka</author><author>Dexmedetomidine for Long-Term Sedation, Investigators</author></authors></contributors><auth-address>Department of Intensive Care Medicine, Bern University Hospital and University of Bern, Bern, Switzerland.</auth-address><titles><title>Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>JAMA</full-title></periodical><pages>1151-1160</pages><volume>307</volume><number>11</number><dates><year>2012</year><pub-dates><date>2012/3/21</date></pub-dates></dates><isbn>0098-7484</isbn><urls><related-urls><url> Papers/J/Jakob et al. 2012 - Dexmedetomidine vs midazolam or propofol for sedati ... ng prolonged mechanical ventilation - two randomized controlled trials.pdf</url></pdf-urls></urls><electronic-resource-num>10.1001/jama.2012.304</electronic-resource-num></record></Cite></EndNote>[36]References ADDIN EN.REFLIST 1.Bugedo G, Tobar E, Aguirre M, Gonzalez H, Godoy J, Lira MT, Lora P, Encalada E, Hernandez A, Tomicic V et al: The implementation of an analgesia-based sedation protocol reduced deep sedation and proved to be safe and feasible in patients on mechanical ventilation. 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