Cellular and molecular mechanisms of asthma and COPD
ATP may enhance the release of mast cell mediators via P2Y2 receptors and activation of the inflammasome via P2X7 receptors. ATP is a potent activator of airway afferent nerves via P2X2/3 receptors and an antagonist of P2X3 receptors is effective as an anti-tussive agent [127]. ................
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