Oral Opioid Dosing Equivalents and Conversions - Wicha Lab
Due to its function through NMDA receptors in addition to mu-receptors as well as its accumulation and excretion into the circulation from the liver, the relative potency of methadone to morphine increases considerably as morphine doses increase. Approximate equivalencies: Morphine PO 30-90 mg 90-300 mg 300-500 mg > 500 mg ................
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