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Luliconazole 1% Cream (LuzuTM)
National Drug Monograph
June 2014
VA Pharmacy Benefits Management Services,
Medical Advisory Panel, and VISN Pharmacist Executives
The purpose of VA PBM Services drug monographs is to provide a comprehensive drug review for making formulary decisions. These documents will be updated when new clinical data warrant additional formulary discussion. Documents will be placed in the Archive section when the information is deemed to be no longer current.
Executive Summary:
• Luliconazole 1% cream is a topical antifungal agent and belongs to the azole class of antifungals.
• Luliconazole is indicated in patients 18 years or older for treatment of tinea pedis (athlete’s foot), tinea cruris (jock itch, affecting tissue surrounding and/or including the groin), and tinea corporis (ringworm).
• Luliconazole is applied once daily with duration of treatment of 2 weeks for tinea pedis and 1 week for tinea cruris and tinea corporis.
• In the tinea cruris pivotal clinical trial, 21.2% of luliconazole treated subjects with tinea cruris achieved complete mycologic and clinical clearance compared to 4.4% of subjects treated with vehicle cream (p ................
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