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Dose Escalation Schedule Dose Level Dose of [IND Agent]* Level 1 – Starting Dose Level 2 Level 3 Level 4 Level 5 *Doses are stated as exact dose in units (e.g., mg/m2, mcg/kg, etc.) rather than as a percentage. Examples for phase 1 combination protocols: Dose Escalation Schedule Dose Level Dose* [Agent X] (units) [Agent Y] ................
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